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MRGPRF Gene

protein-coding   GIFtS: 48
GCID: GC11M068771

MAS-Related GPR, Member F

(Previous names: G protein-coupled receptor 168, G protein-coupled receptor...)
(Previous symbols: GPR168, GPR140)
  See MRGPRF-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MAS-Related GPR, Member F1 2     G-Protein Coupled Receptor 1402 3
GPR1401 2 3     G-Protein Coupled Receptor 1682 3
GPR1681 2 3     RTA2 5
MRGF2 3 5     G Protein-Coupled Receptor MrgF2
G Protein-Coupled Receptor 1401 2     Mas-Related G Protein-Coupled MRGF2
G Protein-Coupled Receptor 1681 2     Mas-Related G-Protein Coupled Receptor Member F2
Mas-Related Gene F Protein2 3     Seven Transmembrane Helix Receptor2

External Ids:    HGNC: 248281   Entrez Gene: 1165352   Ensembl: ENSG000001729357   OMIM: 6072335   UniProtKB: Q96AM13   

Export aliases for MRGPRF gene to outside databases

Previous GC identifers: GC11M068548 GC11M068528 GC11M065111


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MRGPRF Gene:
MRGPRF (MAS-related GPR, member F) is a protein-coding gene. Diseases associated with MRGPRF include intestinal schistosomiasis. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX3.

UniProtKB/Swiss-Prot: MRGRF_HUMAN, Q96AM1
Function: Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development,
including the sensation or modulation of pain (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRGPRF gene promoter:
         E2F-3a   E2F-4   E2F-5   AP-4   E2F-2   LCR-F1   Ik-3   E2F-1   E2F   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRGPRF promoter sequence
   Search Chromatin IP Primers for MRGPRF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRGPRF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.3   Ensembl cytogenetic band:  11q13.3   HGNC cytogenetic band: 11q13.1

MRGPRF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRGPRF gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M068771:  view genomic region     (about GC identifiers)

Start:
68,771,862 bp from pter      End:
68,780,877 bp from pter
Size:
9,016 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MRGRF_HUMAN, Q96AM1 (See protein sequence)
Recommended Name: Mas-related G-protein coupled receptor member F  
Size: 343 amino acids; 38171 Da
Secondary accessions: B3KV43 Q8NBK8

Explore the universe of human proteins at neXtProt for MRGPRF: NX_Q96AM1

Explore proteomics data for MRGPRF at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn4

  • See MRGPRF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001091985.1  NP_659452.3  

    ENSEMBL proteins: 
     ENSP00000309782   ENSP00000323414   ENSP00000403660  

    MRGPRF Human Recombinant Protein Products:

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    Novus Biologicals MRGPRF Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRGPRF

     
    Search eBioscience for Proteins for MRGPRF 

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    Cloud-Clone Corp. CLIAs for MRGPRF
    Search eBioscience for ELISAs for MRGPRF 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPCRAO: GPCR / Class A : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: MRGPRF
    Class A Orphans

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR026228 MRGPCRF
     IPR026234 MRGPCRFAMILY
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q96AM1

    ProtoNet protein and cluster: Q96AM1

    UniProtKB/Swiss-Prot: MRGRF_HUMAN, Q96AM1
    Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily


    Find genes that share domains with MRGPRF           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MRGRF_HUMAN, Q96AM1
    Function: Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development,
    including the sensation or modulation of pain (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
         
    Find genes that share ontologies with MRGPRF           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for MRGPRF:
     Cell cycle / mitosis defect  Decreased homologous recombina  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRGPRF
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRGPRF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRGPRF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRGPRF

    miRNA
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    Block miRNA regulation of human, mouse, rat MRGPRF using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate MRGPRF:
    hsa-miR-33a* hsa-miR-3163 hsa-miR-548a-3p hsa-miR-548e hsa-miR-1182
    SwitchGear 3'UTR luciferase reporter plasmidMRGPRF 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MRGPRF

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    GenScript: all cDNA clones in your preferred vector (see all 2): MRGPRF (NM_001098515)
    Sino Biological Human cDNA Clone for MRGPRF
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRGPRF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRGPRF

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRGPRF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MRGRF_HUMAN, Q96AM1: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with MRGPRF           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including MRGPRF: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for MRGPRF

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----

    Find genes that share ontologies with MRGPRF           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRGPRF (MRGRF)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MRGPRF gene (2 alternative transcripts): 
    NM_001098515.1  NM_145015.4  

    Unigene Cluster for MRGPRF:

    MAS-related GPR, member F
    Hs.118513  [show with all ESTs]
    Unigene Representative Sequence: NM_001098515
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000309099 ENST00000320913 ENST00000441623(uc001ooo.4 uc001oop.4)

    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate MRGPRF:
    hsa-miR-33a* hsa-miR-3163 hsa-miR-548a-3p hsa-miR-548e hsa-miR-1182
    SwitchGear 3'UTR luciferase reporter plasmidMRGPRF 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRGPRF
    Predesigned siRNA for gene silencing in human, mouse, rat MRGPRF
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRGPRF
      QuantiTect SYBR Green Assays in human, mouse, rat MRGPRF
      QuantiFast Probe-based Assays in human, mouse, rat MRGPRF

    Additional mRNA sequence: 

    AK075450.1 AK075492.1 AK098317.1 AK122669.1 AK131068.1 AK293469.1 AL049451.1 BC016964.1 

    6 DOTS entries:

    DT.85105428  DT.100023984  DT.120683122  DT.120683126  DT.95223250  DT.99948386 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MRGPRF    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d
    SP1:                                -                           
    SP2:                          -     -     -                     
    SP3:                                -                           
    SP4:                                                            


    ECgene alternative splicing isoforms for MRGPRF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRGPRF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGACCCACT
    MRGPRF Expression
    About this image


    MRGPRF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Line H9 (Naive)
     
     Neural Crest (Gastrulation Derivatives)
             PureStem MEL2, NCr-fac Progenitor
    MRGPRF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRGPRF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.118513
        Pathway & Disease-focused RT2 Profiler PCR Array including MRGPRF: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRGPRF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MRGPRF gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrgprf1 , 5 MAS-related GPR, member F1, 5 83.97(n)1
    86.01(a)1
      7 (89.05 cM)5
    2115771  NM_145379.21  NP_663354.11 
     1453008285 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    24(a)
    1 → many
    JH376180.1(56001-57008)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 16)
    Uncharacterized protein
    (see all 16)
    32(a)
    30(a)
    (see all 16)
    many ↔ many
    many ↔ many
    (see all 16)
    4(16488532-16489341)
    4(16394563-16395360)


    ENSEMBL Gene Tree for MRGPRF (if available)
    TreeFam Gene Tree for MRGPRF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRGPRF gene
    MRGPRX32  MRGPRD2  MRGPRG2  MAS12  MAS1L2  MRGPRX42  MRGPRX12  MRGPRE2  
    MRGPRX22  
    8 SIMAP similar genes for MRGPRF using alignment to 2 protein entries:     MRGRF_HUMAN (see all proteins):
    MRGPRX2    MRGPRX1    MRGPRX4    MRGPRD    MAS1    MRGPRX3
    MRGPRE    MRGPRG

    Find genes that share paralogs with MRGPRF           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRGPRF (see all 255)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3756333641,2
    C--68696163(+) GGGGG-/GGTCCCA 2 -- int11Minor allele frequency- GG:0.00NA 2
    rs1116626791,2
    F--68771542(+) CCCAGA/GGCCTG 2 -- int12Minor allele frequency- G:0.02CSA WA 120
    rs1906983801,2
    C--68771651(+) CACGGC/TTCCCT 2 -- int10--------
    rs1841931241,2
    C--68771730(+) CCTGAA/GAGCAG 2 -- int10--------
    rs1887447681,2
    --68771741(+) AGGCAA/GAGAGC 2 -- int10--------
    rs128036421,2
    C,F,H--68771755(+) GTGTGC/AGGGAG 2 -- int118Minor allele frequency- A:0.13NS EA NA WA 2342
    rs1412173771,2
    --68771767(+) GCTGGC/TGGGGG 2 -- int10--------
    rs1456020321,2
    --68771781(+) CCACCC/TGTCCC 2 -- int10--------
    rs1510834831,2
    --68771782(+) CACCCA/GTCCCG 2 -- int10--------
    rs1411173511,2
    --68771950(+) ACAGTA/GCCAGT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for MRGPRF (68771862 - 68780877 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MRGPRF:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv468619CNV Loss19166990
    nsv832196CNV Loss17160897
    nsv527120CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRGPRF
    DNA2.0 Custom Variant and Variant Library Synthesis for MRGPRF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607233    OMIM disorders: --

    1 disease for MRGPRF:    
    About MalaCards
    intestinal schistosomiasis

    1 disease from the University of Copenhagen DISEASES database for MRGPRF:
    Intestinal schistosomiasis

    Find genes that share disorders with MRGPRF           About GenesLikeMe


    Export disorders for MRGPRF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRGPRF gene integrated from 10 sources:
    (articles sorted by number of sources associating them with MRGPRF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    6. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. (PubMed id 11551509)1 Dong X.... Anderson D.J. (Cell 2001)
    7. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (Science 2001)
    8. RTA, a candidate G protein-coupled receptor: cloning, sequencing, and tissue distribution. (PubMed id 2109324)1 Ross P.C....Lynch K.R. (Proc. Natl. Acad. Sci. U.S.A. 1990)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 116535 HGNC: 24828 Ensembl:ENSG00000172935 euGenes: HUgn116535 ECgene: MRGPRF
    H-InvDB: MRGPRF

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRGPRF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRGPRF gene:
    Search GeneIP for patents involving MRGPRF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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