MRFAP1L1 Gene
protein-coding GIFtS: 41
GCID: GC04M006709
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Morf4 family associated protein 1-like 1
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Aliases
for MRFAP1L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Morf4 Family Associated Protein 1-Like 11 2 | | MGC96511 | | MORF4 Family-Associated Protein 1-Like 12 |
Export aliases for MRFAP1L1 gene to outside databasesPrevious GC identifers: GC04M006828 GC04M006641 |
Summaries
for MRFAP1L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MRFAP1L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006051.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MRFAP1L1 gene promoter:
Max1 NRSF form 1 HTF Olf-1 CUTL1 NRSF form 2 Arnt GATA-1 COMP1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for MRFAP1L1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRFAP1L1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.1 Ensembl cytogenetic band: 4p16.1 HGNC cytogenetic band: 4p16.1MRFAP1L1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M006709: view genomic region
(about GC identifiers)
Start:
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6,709,428 bp from pter |
End:
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6,711,607 bp from pter |
Size:
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2,180 bases |
Orientation:
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minus strand |
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Proteins
for MRFAP1L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MR1L1_HUMAN, Q96HT8 (See
protein sequence)Recommended Name: MORF4 family-associated protein 1-like 1 Size: 127 amino acids; 14808 Da
Sequence caution: Sequence=AAF67011.1; Type=Frameshift; Positions=89;
Secondary accessions: B2R6R0 Q6NXT8 Q9P0J5Explore the universe of human proteins at neXtProt for MRFAP1L1: NX_Q96HT8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96HT8
MRFAP1L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_982287.1
ENSEMBL proteins: ENSP00000318154
Human Recombinant Protein Products for MRFAP1L1:
MRFAP1L1 Antibody Products:
Assay Products for MRFAP1L1: |
Protein
Domains /
Families
for MRFAP1L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96HT8 UniProtKB/Swiss-Prot: MR1L1_HUMAN, Q96HT8Similarity: Belongs to the MORF4 family-associated protein family |
Function
for MRFAP1L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for MRFAP1L1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MRFAP1L1 (NM_203462) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRFAP1L1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRFAP1L1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRFAP1L1 |
|
Pathways & Interactions
for MRFAP1L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRFAP1L1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/11 Interacting proteins for MRFAP1L1 (Q96HT81, 2, 3 ENSP000003181544) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
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Drugs & Compounds
for MRFAP1L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MRFAP1L1
Search CenterWatch for drugs/clinical trials and news about MRFAP1L1 / MR1L1
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Transcripts
for MRFAP1L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MRFAP1L1 gene (2 alternative transcripts): NM_152301.3 NM_203462.2 Unigene Cluster for MRFAP1L1: Morf4 family associated protein 1-like 1 Hs.593159 [show with all ESTs]Unigene Representative Sequence: AF2585912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000500563(uc021xlc.1) ENST00000320848(uc003gjo.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MRFAP1L1 (NM_203462) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRFAP1L1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRFAP1L1 |
Additional cDNA sequence: AF155654.1 AF258591.1 AK312676.1 BC008087.1 BC066897.1 8 DOTS entries: DT.100879320 DT.91742629 DT.454684 DT.121229729 DT.100036426 DT.121229752 DT.91809766 DT.101984837 24/320 AceView cDNA sequences (see all 320): AI886220 BE744496 BX380435 AA601582 CR590278 BM725678 BU735596 BM698198 AA659711 BI092006 AA311957 AA659730 CR603188 BF438937 BM697819 AI360691 BQ672459 CR607295 CR592660 CR595817 CR602726 T48541 AA307201 AI815511
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for MRFAP1L1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 |
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| SP1: | | | | | | | |
| SP2: | | | | | | |
ECgene alternative splicing isoforms for MRFAP1L1
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Expression
for MRFAP1L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MRFAP1L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCAAAGCCC
About this image
See MRFAP1L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRFAP1L1
SOURCE GeneReport for Unigene cluster: Hs.593159
SABiosciences Custom PCR Arrays for MRFAP1L1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRFAP1L1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRFAP1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRFAP1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRFAP1L1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRFAP1L1 |
Orthologs
for MRFAP1L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for MRFAP1L1 (if available)
TreeFam Gene Tree for MRFAP1L1 (if available) |
Paralogs
for MRFAP1L1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MRFAP1L1 gene
- MRFAP12
1 SIMAP similar gene for MRFAP1L1 using alignment to 1 protein entry: MR1L1_HUMAN:MRFAP1
MRFAP1L1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MRFAP1L1
PGOHUM00000245818
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Genomic Variants
for MRFAP1L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MRFAP1L1 (6709428 - 6711607 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MRFAP1L1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRFAP1L1 |
|
Disorders
/ Diseases
for MRFAP1L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for MRFAP1L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MRFAP1L1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MRFAP1L1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)2 Wan D....Gu J. (2004)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)2 Hu R.-M.... Chen J.-L. (2000)
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External Searches for MRFAP1L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing MRFAP1L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MRFAP1L1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MRFAP1L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MRFAP1L1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for MRFAP1L1 gene:
Search GeneIP for patents involving MRFAP1L1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MRFAP1L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MRFAP1L1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRFAP1L1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRFAP1L1 | | | OriGene Protein Over-expression Lysate for MRFAP1L1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MRFAP1L1 | | OriGene 3'-UTR Clone for MRFAP1L1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRFAP1L1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MRFAP1L1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MRFAP1L1 | | OriGene Custom Protein Services for MRFAP1L1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRFAP1L1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRFAP1L1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRFAP1L1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRFAP1L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRFAP1L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRFAP1L1 |
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 | | | MRFAP1L1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRFAP1L1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for MRFAP1L1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRFAP1L1 |
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