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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MREG Gene

protein-coding GIFtS: 43
GCID: GC02M216807

melanoregulin

Explore 3 diseases affiliated with
MREG via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Melanoregulin¹
DSU¹ ² ³ ⁵
WDT2¹ ²
Dilute Suppressor Protein Homolog² ³
FLJ10116¹
Whn-Dependent Transcript 2²

External Ids:	HGNC: 25478¹	Entrez Gene: 55686²	Ensembl: ENSG00000118242⁷	OMIM: 609207⁵	UniProtKB: Q8N565³

Export aliases for MREG gene to outside databases

Previous GC identifers: GC02M216516 GC02M208664

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MREG_HUMAN, Q8N565

Function: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the

biogenesis of disk membranes of photoreceptor rod cells (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005403.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MREG gene promoter:
AML1a NF-kappaB NF-AT C/EBPalpha RORalpha1 c-Rel NF-AT4 NF-AT2 NF-AT3 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MREG promoter sequence

Search SABiosciences Chromatin IP Primers for MREG

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MREG

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35 Ensembl cytogenetic band: 2q35 HGNC cytogenetic band: 2q35

MREG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MREG gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M216807: view genomic region (about GC identifiers)

Start:	216,807,314 bp from pter	End:	216,898,819 bp from pter
Size:	91,506 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MREG_HUMAN, Q8N565 (See protein sequence)

Recommended Name: Melanoregulin

Size: 214 amino acids; 24927 Da

Subunit: Interacts with PRPH2 (By similarity)

Subcellular location: Apical cell membrane; Peripheral membrane protein (By similarity). Note=Localizes to the inner

segment and basal outer segment of rods in the retina (By similarity)

Secondary accessions: Q53R89 Q53TC1 Q5XKB6 Q9NWC9 Q9P1S1

Alternative splicing: 2 isoforms: Q8N565-1 Q8N565-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MREG: NX_Q8N565

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N565

MREG Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_060470.2

ENSEMBL proteins:

ENSP00000406782 ENSP00000263268 ENSP00000411076 ENSP00000413302 ENSP00000404470

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	Uscn Proteins for MREG

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016324	apical plasma membrane	IEA	--

MREG for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q8N565

UniProtKB/Swiss-Prot: MREG_HUMAN, Q8N565

Similarity: Belongs to the melanoregulin family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MREG_HUMAN, Q8N565

Function: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the

biogenesis of disk membranes of photoreceptor rod cells (By similarity)

Phenotypes:
7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mreg):

behavior/neurological	integument	muscle	nervous system	normal
pigmentation	vision/eye

MREG for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MREG

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MREG

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MREG

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for MREG (ENSP00000263268⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030318	melanocyte differentiation	IEA	--
GO:0042640	anagen	IEA	--
GO:0043473	pigmentation	--	--
GO:0048066	developmental pigmentation	--	--

MREG for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MREG
Search CenterWatch for drugs/clinical trials and news about MREG

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for MREG gene:

NM_018000.2

Unigene Cluster for MREG:

Melanoregulin

Hs.620391 [show with all ESTs]

Unigene Representative Sequence: NM_018000

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000423087(uc002vfo.3) ENST00000263268 ENST00000439791 ENST00000424992

ENST00000420348

miRNA Products:		OriGene 3'-UTR Clone: MREG Browse OriGene MicroRNA Expression Plasmids
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		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate MREG (see all 28):
		hsa-miR-498 hsa-miR-4254 hsa-miR-3607-3p hsa-miR-944 hsa-miR-138-2* hsa-miR-1205 hsa-miR-1297 hsa-miR-378b

		SwitchGear 3'UTR luciferase reporter plasmid: MREG 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Additional cDNA sequence:

AF068290.1 AK000978.1

8 DOTS entries:

DT.92423943 DT.100812382 DT.120945432 DT.95274384 DT.120945429 DT.92423944 DT.205768 DT.95114238

24/70 AceView cDNA sequences (see all 70):

AI089810 AW182843 CB529033 BC032747 BQ939081 BQ958428 BM692776 BG032393

CR604344 BQ928130 AK000978 BX401402 BG167210 AA621713 AA557145 BE042763

AI564124 NM_018000 BQ214197 BG388147 BI859498 AA364072 CN481592 BU552477

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MREG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATGTAAAA

About this image

MREG expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Ovigerous Cord

Ovarian Somatic Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MREG Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MREG

SOURCE GeneReport for Unigene cluster: Hs.620391

UniProtKB/Swiss-Prot: MREG_HUMAN, Q8N565

Tissue specificity: Expressed in photoreceptor cells (at protein level)

SABiosciences Custom PCR Arrays for MREG

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MREG

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MREG

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MREG gene from 5/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mreg^{1 , 5}	melanoregulin^{1, 5}	84.42(n)¹ 85.98(a)¹		1 (36.39 cM)⁵ 381269¹ NM_001005423.2¹ NP_001005423.1¹ 72159233⁵
chicken (Gallus gallus)	Aves	MREG¹	melanoregulin	73.78(n) 78.65(a)		424013 XM_421870.3 XP_421870.3
lizard (Anolis carolinensis)	Reptilia	MREG⁶	--	80(a)	1 ↔ 1	1(117149487-117176114)
African clawed frog (Xenopus laevis)	Amphibia	Xl.16882²	Xenopus laevis transcribed sequence with weak similarity more	72.47(n)		BJ068712.1
zebrafish (Danio rerio)	Actinopterygii	zgc:91968¹	zgc:91968	50.93(n) 49.44(a)		431714 NM_001002167.1 NP_001002167.1

ENSEMBL Gene Tree for MREG (if available)
TreeFam Gene Tree for MREG (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MREG gene

MREG for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for MREG
PGOHUM00000239393

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs185834351^1,2		--	216806855(+)	`TTTGAA/TCTACT`	1	--	ds500¹		0	--	--	--	--
rs77471135^1,2	F	--	216806886(+)	`GTGCAT/CTTTAA`	1	--	ds500¹		1		WA	118
rs149768949^1,2		--	216806898(+)	`ATAAAA/TATTAA`	1	--	ds500¹		0	--	--	--	--
rs145712727^1,2		--	216806905(+)	`TTAATA/GTAAAA`	1	--	ds500¹		0	--	--	--	--
rs200835217^1,2		--	216806985(+)	`AATAT-/AAAAAA`	1	--	ds500¹		0	--	--	--	--
rs190304531^1,2		--	216807066(+)	`TTCTGG/TGGCTA`	1	--	ds500¹		0	--	--	--	--
rs13030380^1,2	C,F	--	216807127(+)	`CCTGCG/ACCCCT`	1	--	ds500¹		4		NA	126
rs13030243^1,2	C,F,H	--	216807227(+)	`TTCAGC/TCTCTC`	1	--	ds500¹		9		NS EA NA WA	660
rs181092894^1,2		--	216807258(+)	`TTATGA/GAAAGA`	1	--	ds500¹		0	--	--	--	--
rs148521245^1,2		--	216807316(+)	`AAGTAA/CATACA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MREG (216807314 - 216898819 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MREG: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MREG

DNA2.0 Custom Variant and Variant Library Synthesis for MREG

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MREG for disorders           About GeneDecksing

OMIM gene information: 609207    OMIM disorders: --

3 diseases for MREG:    About MalaCards

chronic obstructive pulmonary disease methemoglobinemia pulmonary disease

2 diseases from the University of Copenhagen DISEASES database for MREG:

Ocular albinism Hermansky-Pudlak syndrome

Human Genome Epidemiology (HuGE) Navigator: MREG (1 document)

Export disorders for MREG gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MREG gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with MREG)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Multistudy fine mapping of chromosome 2q identifies X RCC5 as a chronic obstructive pulmonary disease susceptibility gene. (PubMed id 20463177)¹ Hersh C.P....Silverman E.K. (2010)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator. (PubMed id 17260955)² Boesze-Battaglia K.... Damek-Poprawa M. (2007)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)² Hillier L.W....Wilson R.K. (2005)
dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. (PubMed id 15550542)¹ O'Sullivan T.N....Jenkins N.A. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 55686	HGNC: 25478	AceView: FLJ10116	Ensembl:ENSG00000118242	euGenes: HUgn55686
ECgene: MREG	H-InvDB: MREG

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MREG	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MREG gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MREG gene:
Search GeneIP for patents involving MREG

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


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	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for MREG
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MREG		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MREG
	OriGene Protein Over-expression Lysate for MREG		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for MREG		OriGene 3'-UTR Clone for MREG
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MREG		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MREG
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for MREG		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for MREG		OriGene Custom Protein Services for MREG
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MREG
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MREG
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MREG
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MREG
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MREG
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MREG

	GenScript Custom Purified and Recombinant Proteins Services for MREG		GenScript cDNA clones with any tag delivered in your preferred vector for MREG
	GenScript Custom Assay Services for MREG		GenScript Custom Superior Antibodies Services for MREG
	GenScript Custom overexpressing Cell Line Services for MREG		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in MREG promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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MREG Proteins, Antibodies, CLIAs, and ELISAs

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MREG

	SwitchGear 3'UTR luciferase reporter plasmids for MREG
	SwitchGear Promoter luciferase reporter plasmids for MREG

Search ThermoFisher Antibodies for MREG

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MREG

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MREG

Sirion Biotech Customized:

	stable knockdown cell line services for MREG
	inducible knockdown cell line services for MREG
	design and validation of potent shRNA sequences against MREG
	adenovirus for potent knockdown of MREG
	adenovirus for overexpression of MREG
	stable overexpressing cell line services for MREG
	inducible overexpressing cell line services for MREG

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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MREG Gene

melanoregulin

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MREG Gene

melanoregulin

Aliasesfor MREG gene

Summariesfor MREG gene

Genomic Viewsfor MREG gene

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Pathways & Interactionsfor MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

Expression
for MREG gene

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for MREG gene

Genomic Variants
for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene

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for MREG gene