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MPZL2 Gene

protein-coding   GIFtS: 49
GCID: GC11M118124

Myelin Protein Zero-Like 2

(Previous name: epithelial V-like antigen 1)
(Previous symbol: EVA1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Myelin Protein Zero-Like 21 2
EVA11 2 3 5
Epithelial V-Like Antigen 11 2 3
EVA2 3 5
Myelin Protein Zero-Like Protein 22

External Ids:    HGNC: 34961   Entrez Gene: 102052   Ensembl: ENSG000001495737   OMIM: 6048735   UniProtKB: O604873   

Export aliases for MPZL2 gene to outside databases

Previous GC identifers: GC11M117630 GC11M114057


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MPZL2 Gene:
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the
organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte
developmental progression. This gene is expressed in the thymus and in several epithelial structures early in
embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines,
is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to
mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might
imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic
V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine
phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants
encoding the same protein have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for MPZL2 Gene:
MPZL2 (myelin protein zero-like 2) is a protein-coding gene. Diseases associated with MPZL2 include enlarged vestibular aqueduct, and carotid stenosis. An important paralog of this gene is SCN2B.

UniProtKB/Swiss-Prot: MPZL2_HUMAN, O60487
Function: Mediates homophilic cell-cell adhesion




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NC_018922.2  NT_033899.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the MPZL2 gene promoter:
         GR   AhR   GCNF   LCR-F1   Arnt   PPAR-gamma1   GCNF-1   c-Myb   PPAR-gamma2   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMPZL2 promoter sequence
   Search Chromatin IP Primers for MPZL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MPZL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q24

MPZL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MPZL2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M118124:  view genomic region     (about GC identifiers)

Start:
118,124,118 bp from pter      End:
118,135,251 bp from pter
Size:
11,134 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MPZL2_HUMAN, O60487 (See protein sequence)
Recommended Name: Myelin protein zero-like protein 2 precursor  
Size: 215 amino acids; 24484 Da
Secondary accessions: A8K2R1

Explore the universe of human proteins at neXtProt for MPZL2: NX_O60487

Explore proteomics data for MPZL2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn39, Asn118
  • Modification sites at PhosphoSitePlus

  • See MPZL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_005788.1  NP_658911.1  

    ENSEMBL proteins: 
     ENSP00000278937   ENSP00000408362  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    VSET: Immunoglobulin superfamily / V-set domain containing

    5 InterPro protein domains:
     IPR003596 Ig_V-set_subgr
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR000920 Myelin_P0

    Graphical View of Domain Structure for InterPro Entry O60487

    ProtoNet protein and cluster: O60487

    2 Blocks protein domains:
    IPB003596 Immunoglobulin V-type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: MPZL2_HUMAN, O60487
    Similarity: Belongs to the myelin P0 protein family
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    MPZL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MPZL2_HUMAN, O60487
    Function: Mediates homophilic cell-cell adhesion

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    MPZL2 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mpzl2):
     hematopoietic system  immune system 

    MPZL2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Mpzl2tm1Lex for MPZL2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MPZL2
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    hsa-miR-338-5p hsa-miR-145 hsa-miR-556-3p hsa-miR-578 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidMPZL2 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MPZL2_HUMAN, O60487: Membrane; Single-pass type I membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    plasma membrane3
    endoplasmic reticulum1
    extracellular1
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton TAS9585423
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    MPZL2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MPZL2
    Interactions:

        Search GeneGlobe Interaction Network for MPZL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for MPZL2 (O604871 ENSP000002789374) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MPZL3Q6UWV21, ENSP000002789494EBI-3906725,EBI-4314854 STRING: ENSP00000278949
    TAPBPLENSP000002665564STRING: ENSP00000266556
    NCR3LG1ENSP000003416374STRING: ENSP00000341637
    ATF4ENSP000003367904STRING: ENSP00000336790
    MESTENSP000002232154STRING: ENSP00000223215
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion TAS9585423
    GO:0009653anatomical structure morphogenesis TAS9585423
    GO:0016337cell-cell adhesion ----
    GO:0033077T cell differentiation in thymus IEA--

    MPZL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for MPZL2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MPZL2 gene (2 alternative transcripts): 
    NM_005797.3  NM_144765.2  

    Unigene Cluster for MPZL2:

    Myelin protein zero-like 2
    Hs.116651  [show with all ESTs]
    Unigene Representative Sequence: NM_005797
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000278937(uc001psn.3) ENST00000534175 ENST00000528554 ENST00000438295(uc001pso.3)
    ENST00000529376 ENST00000527282 ENST00000525647
    miRNA
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    hsa-miR-338-5p hsa-miR-145 hsa-miR-556-3p hsa-miR-578 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidMPZL2 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MPZL2
      QuantiTect SYBR Green Assays in human, mouse, rat MPZL2
      QuantiFast Probe-based Assays in human, mouse, rat MPZL2

    Additional mRNA sequence: 

    AF030455.1 AF275945.1 AF304447.1 AK290326.1 AY359061.1 BC017774.1 

    6 DOTS entries:

    DT.305093  DT.92415865  DT.70102502  DT.100021078  DT.100760907  DT.40113953 

    Selected AceView cDNA sequences (see all 169):

    BU192146 CB306409 AA700901 BE047319 AI470281 AL602699 AI003314 AW167185 
    BQ272389 NM_005797 AA928214 BX503380 BQ719162 CA448496 AI564587 AI370660 
    AI961901 AA860685 AW614869 AI628927 AA668897 CR626217 BM353656 AI220250 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MPZL2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b
    SP1:                                -                 -                                   -     -           -               
    SP2:                                -                 -                                   -     -                           
    SP3:                                -                 -                                                                     
    SP4:                                -                 -                                                                     
    SP5:                                -                                                                                       


    ECgene alternative splicing isoforms for MPZL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MPZL2 expression in normal human tissues (normalized intensities)      MPZL2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCAGTGACG
    MPZL2 Expression
    About this image


    MPZL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 14) fully expand
     
     Kidney (Urinary System)    fully expand to see all 4 entries
             Ureteric Bud Cells Ureteric Bud
             Renal Collecting Duct System
     
     Epiblast (Early Embryonic Tissues)    fully expand to see all 2 entries
             Epiblast Cells Epiblast
             Epiblast Stem Cell line 5
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Thoracic Perivascular Adipose
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Monocytes Peripheral Blood
     
     Inner Cell Mass (Early Embryonic Tissues)
             Blimp1- mVenus and stella-ECFP genetically modified stem cells
    MPZL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MPZL2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.116651

    UniProtKB/Swiss-Prot: MPZL2_HUMAN, O60487
    Tissue specificity: Expressed in thymocytes and thymic stromal cells; expression elevated in some T-cell leukemias

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPZL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MPZL2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mpzl21 , 5 myelin protein zero-like 21, 5 84.34(n)1
    81.4(a)1
      9 (24.84 cM)5
    140121  NM_007962.41  NP_031988.21 
     450424255 
    chicken
    (Gallus gallus)
    Aves MPZL21 myelin protein zero-like 2 64.48(n)
    59.02(a)
      419779  NM_001252284.1  NP_001239213.1 
    lizard
    (Anolis carolinensis)
    Reptilia MPZL26
    myelin protein zero-like 2
    52(a)
    1 ↔ 1
    GL343767.1(114910-119351)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia 1377325612   -- 72.48(n)    137732561 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005346821 myelin protein zero-like protein 2-like 51.99(n)
    44.56(a)
      100534682  XM_003200105.2  XP_003200153.2 


    ENSEMBL Gene Tree for MPZL2 (if available)
    TreeFam Gene Tree for MPZL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MPZL2 gene
    SCN2B2  MPZ2  MPZL32  MPZL12  SCN4B2  
    5 SIMAP similar genes for MPZL2 using alignment to 1 protein entry:     MPZL2_HUMAN:
    MPZL1    SCN2B    MPZ    P0    MPZL3

    MPZL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MPZL2 (see all 276)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17154541,2
    C,F,O,H--118125044(-) AAAATT/CCAGGG 1 -- ut31 ese314Minor allele frequency- C:0.08MN NA NS EA WA CSA 736
    rs17154531,2
    C,F,O,A,H--118125077(-) AAAAAG/AATTGT 1 -- ut3116Minor allele frequency- A:0.41MN NA NS WA CSA EA 911
    rs355126381,2
    C,F--118125183(+) CTATCC/TGTCAC 1 -- ut314Minor allele frequency- T:0.16WA NA 126
    rs30183661,2
    C,F,O,H--118125322(-) CACAAC/TGCTAA 1 -- ut3115Minor allele frequency- T:0.12NA NS EA CSA WA 1424
    rs1162193371,2
    F--118125330(+) GTGCTA/GTTGTA 1 -- ut311Minor allele frequency- G:0.01WA 118
    rs17931521,2
    C,F,H--118125359(-) TTTGTT/CGTTTT 1 -- ut319Minor allele frequency- C:0.10NS EA NA WA CSA 428
    rs1808153611,2
    --118125383(+) GAATAC/TTGAAA 1 -- ut310--------
    rs1454063241,2
    C--118125402(+) GTAAAA/GCAAGA 1 -- ut310--------
    rs10565621,2
    C,F,A,H--118125625(-) TCAAAG/AGGGAT 1 -- ut31 ese3110Minor allele frequency- A:0.41MN NS NA EA PA EU CA WA CSA 6699
    rs1852627581,2
    --118125627(+) CCCTTC/TTGATA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MPZL2 (118124118 - 118135251 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MPZL2: --
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604873    OMIM disorders: --

    8 diseases for MPZL2:    About MalaCards
    enlarged vestibular aqueduct    carotid stenosis    choroiditis    t-cell leukemia
    lung cancer    esophagitis    leukemia    endotheliitis


    MPZL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MPZL2

    Export disorders for MPZL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MPZL2 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with MPZL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. (PubMed id 9585423)1, 2, 3 Guttinger M.... Grassi F. (J. Cell Biol. 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. A secreted protein microarray platform for extracellular protein interaction discovery. (PubMed id 21982860)1 Ramani S.R....Gonzalez L.C. (Anal. Biochem. 2012)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. Characterization of epithelial V-like antigen in human choroid plexus epithelial cells: potential role in CNS immune surveillance. (PubMed id 21440040)1 Wojcik E....Carrithers M.D. (Neurosci. Lett. 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. Genome-wide association study of acute post-surgical pain in humans. (PubMed id 19207018)4 Kim H....Dionne R.A. (Pharmacogenomics 2009)
    9. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10205 HGNC: 3496 AceView: EVA1 Ensembl:ENSG00000149573 euGenes: HUgn10205
    ECgene: MPZL2 H-InvDB: MPZL2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MPZL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MPZL2 gene:
    Search GeneIP for patents involving MPZL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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