Aliases for MPZL1 Gene
External Ids for MPZL1 Gene
Previous GeneCards Identifiers for MPZL1 Gene
GeneCards Summary for MPZL1 Gene
MPZL1 (Myelin Protein Zero Like 1) is a Protein Coding gene. Diseases associated with MPZL1 include Noonan Syndrome 1. Among its related pathways are Cell adhesion molecules (CAMs) and Adhesion. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is SCN2B.
UniProtKB/Swiss-Prot for MPZL1 Gene
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.