Aliases for MPZL1 Gene
External Ids for MPZL1 Gene
Previous GeneCards Identifiers for MPZL1 Gene
GeneCards Summary for MPZL1 Gene
MPZL1 (Myelin Protein Zero-Like 1) is a Protein Coding gene. Among its related pathways are Tyrosine Kinases / Adaptors and Adhesion. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is SCN2B.
UniProtKB/Swiss-Prot for MPZL1 Gene
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.