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Mucosal Pentraxin 1 (Pseudogene)
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Aliases
for MPTX1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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| Aliases |
|---|
| Mucosal Pentraxin 1 (Pseudogene)1 2 | | MPTX2 3 |
Export aliases for MPTX1 gene to outside databases |
Summaries
for MPTX1 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
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GeneCards Summary for MPTX1 Gene:
MPTX1 (mucosal pentraxin 1 (pseudogene)) is a pseudogene.
|
Genomic Views
for MPTX1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | Regulatory elements:
 Search for regulatory transcription factor binding sites for MPTX1
Other transcription factors
Search Chromatin IP Primers for MPTX1
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MPTX1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q23.2 Ensembl cytogenetic band: 1q23.2 HGNC cytogenetic band: 1q23.2MPTX1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P159247: view genomic region
(about GC identifiers)
Start:
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159,246,293 bp from pter |
End:
|
159,247,282 bp from pter |
Size:
|
990 bases |
Orientation:
|
plus strand |
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Proteins
for MPTX1 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MPTX_HUMAN, A8MV57 (See
protein sequence)Recommended Name: Putative mucosal pentraxin homolog Size: 137 amino acids; 15138 Da
Caution: Could be the product of a pseudogene. Much shorter in N-terminus than its rodent counterparts due to a
stop codon insertion. However, proteomics data suggest the existence of the proteinExplore the universe of human proteins at neXtProt for MPTX1: NX_A8MV57
MPTX1 Human Recombinant
Protein Products:MPTX1 Antibody
Products:MPTX1 Assay Products: |
Domains /
Families
for MPTX1 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | 3 InterPro protein domains:Graphical View of Domain Structure for InterPro Entry A8MV57 ProtoNet protein and cluster: A8MV57 UniProtKB/Swiss-Prot: MPTX_HUMAN, A8MV57Similarity: Belongs to the pentaxin family
MPTX1 for domains About GeneDecksing
|
Function
for MPTX1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Animal Models:
Inhib. RNA
Products: |  | Browse OriGene RNAi
| | | Predesigned siRNA for gene silencing in human, mouse, rat MPTX1 |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for MPTX1 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for MPTX1  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPTX1 |
Localization
for MPTX1 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Pathways & Interactions
for MPTX1 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MPTX1
Interactions:
Search GeneGlobe Interaction Network for MPTX1
|
Drugs & Compounds
for MPTX1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
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 Browse compounds at ApexBio
 Browse Tocris compounds for MPTX1 (MPTX)
|
Transcripts
for MPTX1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
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2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000480235 ENST00000536945
Inhib. RNA
Products: | | Browse OriGene RNAi
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat MPTX1 |
GeneLoc Exon Structure
|
Expression
for MPTX1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
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See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
MPTX1 Protein expression data from MOPED1, PaxDb2 and
MaxQB3:  --
UniProtKB/Swiss-Prot: MPTX_HUMAN, A8MV57Tissue specificity: Not expressed in the intestinal tract including ascending colon, descending colon and rectum.
Not expressed in the human colon cancer cell lines HT-29 and CaCo-2
Custom PCR Arrays for MPTX1
Primer
Products: | | Browse OriGene qPCR
| | | Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat MPTX1 | | | QuantiTect SYBR Green Assays in human, mouse, rat MPTX1 | | | QuantiFast Probe-based Assays in human, mouse, rat MPTX1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPTX1 |
Orthologs
for MPTX1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
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This gene was present in the common ancestor of human and mouse.
Orthologs for MPTX1 gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mptx15 |
RIKEN cDNA 1810030J14 gene |
-- |
|
1 (81.01 cM) 174330518 |
ENSEMBL Gene Tree for MPTX1 (if available)
TreeFam Gene Tree for MPTX1 (if available) |
Paralogs
for MPTX1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for MPTX1 gene
2 SIMAP similar genes for MPTX1 using alignment to 1 protein entry: MPTX_HUMAN:CRP APCS
MPTX1 for paralogs About GeneDecksing
|
Genomic Variants
for MPTX1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section
TryGeneCards Plus | | | Site Specific Mutation Identification with PCR Assays |
|
Disorders
/ Diseases
for MPTX1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
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Publications
for MPTX1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for MPTX1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with MPTX1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)1 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)
- Dietary modulation and structure prediction of rat mucosal pentraxin (Mptx) protein and loss of function in humans. (PubMed id 18850182)2 van der Meer-van Kraaij C.... Keijer J. (Genes Nutr. 2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
|
External Searches for MPTX1 gene (in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing MPTX1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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|
Other Databases showing MPTX1 gene
(According to HUGE)
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Specialized Databases showing MPTX1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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TryGeneCards Plus | Patent Information for MPTX1 gene:
Search GeneIP for patents involving MPTX1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MPTX1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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 | |
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| | | | |
 |
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|  | Block miRNA regulation of human, mouse, rat MPTX1 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing MPTX1 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MPTX1 | | Predesigned siRNA for gene silencing in human, mouse, rat MPTX1 | | | QuantiFast Probe-based Assays in human, mouse, rat MPTX1 | | QuantiTect SYBR Green Assays in human, mouse, rat MPTX1 | | | Custom PCR Arrays for MPTX1 | | Search Chromatin IP Primers for MPTX1 | | | Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MPTX1 | | Search GeneGlobe Interaction Network for MPTX1 | | | Search Regulatory tfbs for MPTX1 |
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 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPTX1 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for MPTX1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MPTX1 |
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