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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MPP6 Gene

protein-coding   GIFtS: 56
GCID: GC07P024612

Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member...

Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6)1 2     MAGUK P55 Subfamily Member 62
VAM12 3 5     MAGUK Protein P55T2
Veli-Associated MAGUK 12 3     p55T2
VAM-12 3     Protein Associated With Lin7 22
PALS22 5     

External Ids:    HGNC: 181671   Entrez Gene: 516782   Ensembl: ENSG000001059267   OMIM: 6069595   UniProtKB: Q9NZW53   

Export aliases for MPP6 gene to outside databases

Previous GC identifers: GC07P024255 GC07P024355 GC07P024386 GC07P024579 GC07P024544


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MPP6 Gene:
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and
receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal,
and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies,
DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like
(see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the
p55-like MAGUK subfamily (Tseng et al., 2001 (PubMed 11311936)).(supplied by OMIM, Mar 2008)

GeneCards Summary for MPP6 Gene: 
MPP6 (membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)) is a protein-coding gene. Diseases associated with MPP6 include pneumonia, and tuberculosis, and among its related super-pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include protein binding. An important paralog of this gene is MPP7.

Gene Wiki entry for MPP6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MPP6 gene promoter:
         GATA-3   Tal-1beta   c-Ets-1   C/EBPalpha   E47   GATA-1   GATA-2   FOXO1a   Ik-1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMPP6 promoter sequence
   Search SABiosciences Chromatin IP Primers for MPP6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MPP6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15   Ensembl cytogenetic band:  7p15.3   HGNC cytogenetic band: 7p15

MPP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MPP6 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P024612:  view genomic region     (about GC identifiers)

Start:
24,612,887 bp from pter      End:
24,729,159 bp from pter
Size:
116,273 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 24,664,991-24,779,052     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MPP6_HUMAN, Q9NZW5 (See protein sequence)
Recommended Name: MAGUK p55 subfamily member 6  
Size: 540 amino acids; 61117 Da
Subunit: Interacts with CADM1 (By similarity). Interacts with the LIN7 proteins
Subcellular location: Membrane; Peripheral membrane protein (By similarity)
Secondary accessions: A4D157 Q9H0E1

Explore the universe of human proteins at neXtProt for MPP6: NX_Q9NZW5

Explore proteomics data for MPP6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NZW5

  • MPP6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MPP6 Protein Expression
    REFSEQ proteins: NP_057531.2  
    ENSEMBL proteins: 
     ENSP00000395859   ENSP00000222644   ENSP00000386262   ENSP00000379737   ENSP00000391020  
     ENSP00000400515   ENSP00000473560  

    Human Recombinant Protein Products for MPP6: 
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    Novus Biologicals MPP6 Protein
    Novus Biologicals MPP6 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MPP6 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane NAS11311936

    MPP6 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for MPP6 
    Cloud-Clone Corp. CLIAs for MPP6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/9 InterPro protein domains (see all 9):
     IPR008144 Guanylate_kin
     IPR008145 Guanylate_kin/L-typ_Ca_channel
     IPR014775 L27_C
     IPR001452 SH3_domain
     IPR011511 SH3_2

    Graphical View of Domain Structure for InterPro Entry Q9NZW5

    ProtoNet protein and cluster: Q9NZW5

    5 Blocks protein domains:
    IPB001452 SH3 domain signature
    IPB001478 PDZ/DHR/GLGF domain
    IPB004172 L27 domain
    IPB008144 Guanylate kinase
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: MPP6_HUMAN, Q9NZW5
    Similarity: Belongs to the MAGUK family
    Similarity: Contains 1 guanylate kinase-like domain
    Similarity: Contains 2 L27 domains
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 SH3 domain


    MPP6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11311936
         
    MPP6 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for MPP6:
     Decreased CYP1A1 activity afte  Decreased mitotic index  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MPP6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MPP6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MPP6 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MPP6
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate MPP6:
    hsa-miR-3689b hsa-miR-3689e hsa-miR-3163 hsa-miR-3689a-5p hsa-miR-3912
    SwitchGear 3'UTR luciferase reporter plasmidMPP6 3' UTR sequence
    Inhib. RNA
    Products:
        
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPP6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MPP6 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Sertoli-Sertoli Cell Junction Dynamics0.38
    Epithelial Tight Junctions0.36

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MPP6
        Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MPP6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/38 Interacting proteins for MPP6 (Q9NZW53 ENSP000002226444) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AATFQ9NY613, ENSP000002254024I2D: score=2 STRING: ENSP00000225402
    DNM2P505703, ENSP000003527214I2D: score=2 STRING: ENSP00000352721
    EXOSC7Q150243, ENSP000002655644I2D: score=2 STRING: ENSP00000265564
    FTLP027923, ENSP000003665254I2D: score=2 STRING: ENSP00000366525
    LIN7AO149103, ENSP000002612034I2D: score=2 STRING: ENSP00000261203
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006461protein complex assembly NAS11311936

    MPP6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MPP6

    Search CenterWatch for drugs/clinical trials and news about MPP6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MPP6 gene: 
    NM_016447.2  

    Unigene Cluster for MPP6:

    Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
    Hs.533355  [show with all ESTs]
    Unigene Representative Sequence: NM_016447
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432190 ENST00000222644(uc003swy.3) ENST00000409761 ENST00000396475(uc003swx.3)
    ENST00000430180 ENST00000426450 ENST00000472674 ENST00000464384
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MPP6
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate MPP6:
    hsa-miR-3689b hsa-miR-3689e hsa-miR-3163 hsa-miR-3689a-5p hsa-miR-3912
    SwitchGear 3'UTR luciferase reporter plasmidMPP6 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MPP6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MPP6
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MPP6 (NM_016447)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MPP6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MPP6
    Sirion Biotech Customized lentivirus for stable overexpression of MPP6 
                         Customized lentivirus expression plasmids for stable overexpression of MPP6 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MPP6
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MPP6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MPP6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MPP6

    Additional mRNA sequence: 

    AF162130.2 AL136836.1 BC012034.1 BC023638.2 

    5 DOTS entries:

    DT.100777461  DT.110143  DT.92052862  DT.92421919  DT.92421920 

    24/88 AceView cDNA sequences (see all 88):

    BU616523 NM_016447 BQ478257 BM792853 BX445375 BM797518 BQ778013 BF513365 
    BC023638 BC012034 BU686533 CR605092 AL136836 AA811162 BX433120 CD627913 
    BU508031 CB146395 BP340282 CB159113 BG291778 CD627911 AI917302 CA434215 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MPP6 expression in normal human tissues (normalized intensities)      MPP6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAAGGCTG
    MPP6 Expression
    About this image


    MPP6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Adult Dopaminergic Neurons Substantia Nigra pars Compacta
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Leydig Cells Testis Interstitium
             testis ; cells in seminiferus ducts   
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Presumptive Podocytes Podocyte Layer
             kidney ; cells in tubules   
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Islets of Langerhans
             pancreas ; exocrine glandular cells   
     
     Stomach (Gastrointestinal Tract)    fully expand to see all 2 entries
             stomach, upper ; glandular cells   

    See MPP6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MPP6

    SOURCE GeneReport for Unigene cluster: Hs.533355

    UniProtKB/Swiss-Prot: MPP6_HUMAN, Q9NZW5
    Tissue specificity: Abundant in testis, brain, and kidney with lower levels detectable in other tissues

        SABiosciences Expression via Pathway-Focused PCR Array including MPP6: 
              Tight Junctions in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPP6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MPP6 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mpp61 , 5 membrane protein, palmitoylated 6 (MAGUK p55 subfamily more1, 5 90.6(n)1
    98.33(a)1
      6 (24.13 cM)5
    565241  NM_001164733.11  NP_001158205.11 
     501102415 
    chicken
    (Gallus gallus)
    Aves MPP61 membrane protein, palmitoylated 6 (MAGUK p55 subfamily more 84.37(n)
    95.5(a)
      420622  XM_418721.3  XP_418721.2 
    lizard
    (Anolis carolinensis)
    Reptilia MPP66
    Uncharacterized protein
    94(a)
    1 ↔ 1
    6(31032228-31083417)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480242112   -- 81.11(n)    48024211 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556622 similar to membrane protein, palmitoylated 6 (MAGUK more 76.74(n)   394134  BC045417.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG93263
    vari1
    guanylate kinase3
    varicose1
    39(a)
    (best of 2)3
    48.06(n)1
    43.62(a)1
      353431  NM_165342.31  NP_724288.31 


    ENSEMBL Gene Tree for MPP6 (if available)
    TreeFam Gene Tree for MPP6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MPP6 gene
    MPP72  DLG32  MPP52  DLG22  MPP22  MPP42  DLG42  DLG12  
    CASK2  MPP12  MPP32  
    12 SIMAP similar genes for MPP6 using alignment to 6 protein entries:     MPP6_HUMAN (see all proteins):
    MPP2    MPP1    DKFZp666F1010    MPP5    CASK    MPP7
    DKFZp666D023    GUK1    MPP3    DKFZp761P0818    MPP4    DLG2

    MPP6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2554 SNPs in MPP6 are shown (see all 2554)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2001507431,2
    C--24611191(-) TCTTAA/CCCTTA 1 -- us2k10--------
    rs775619451,2
    C--24662991(+) CTATTA/TAGGAT 1 -- us2k10--------
    rs1898086211,2
    --24663062(+) CAGGGC/TAAGTA 1 -- us2k10--------
    rs1178907291,2
    C,F--24663077(+) AGTGGC/TTGGGT 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs38421761,2
    C--24663095(-) TTAAC-/CTTAAC
            
    ACATC
    1 -- us2k10--------
    rs1474878431,2
    --24663143(+) TACAGC/TAGGGA 1 -- us2k10--------
    rs1399476661,2
    --24663192(+) GGCAGA/CAAGAA 1 -- us2k10--------
    rs1820705271,2
    --24663300(+) CAGCCA/GTCCTG 1 -- us2k10--------
    rs1160156071,2
    F--24663329(+) CTACTC/ATGTGC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs761264641,2
    C,F--24663402(+) GGAAAG/AAAGGT 1 -- us2k11Minor allele frequency- A:0.05EA 120

    HapMap Linkage Disequilibrium report for MPP6 (24612887 - 24729159 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for MPP6 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2434979CNV Deletion19546169
    esv1546433CNV Deletion17803354
    esv998133CNV Deletion20482838
    esv4910CNV Deletion18987735
    esv996504CNV Deletion20482838
    esv2734136CNV Deletion23290073
    esv2168364CNV Deletion18987734
    esv8712CNV Loss19470904
    nsv518495CNV Loss19592680
    nsv526721CNV Loss19592680


    Human Gene Mutation Database (HGMD): MPP6
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606959    OMIM disorders: --

    4 diseases for MPP6:    About MalaCards
    pneumonia    tuberculosis    rheumatoid arthritis    arthritis


    MPP6 for disorders           About GeneDecksing


    Export disorders for MPP6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MPP6 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with MPP6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain. (PubMed id 11311936)1, 2, 3, 9 Tseng T.-C.... Chishti A.H. (2001)
    2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    5. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    7. Molecular cloning and characterization of Pals, proteins associated with mLin-7. (PubMed id 10753959)1, 3 Kamberov E....Margolis B. (2000)
    8. Identification of risk loci with shared effects on fiv e major psychiatric disorders: a genome-wide analysis. (PubMed id 23453885)1  ....Sullivan P.F. (2013)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    10. Comprehensive analysis of interactions between the Src -associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PubMed id 22745667)1 Asbach B....Wagner R. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51678 HGNC: 18167 AceView: MPP6 Ensembl:ENSG00000105926 euGenes: HUgn51678
    ECgene: MPP6 H-InvDB: MPP6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MPP6 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MPP6 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MPP6 gene:
    Search GeneIP for patents involving MPP6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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