Aliases for MPP4 Gene
External Ids for MPP4 Gene
Previous HGNC Symbols for MPP4 Gene
Previous GeneCards Identifiers for MPP4 Gene
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for MPP4 Gene
MPP4 (Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4)) is a Protein Coding gene. Diseases associated with MPP4 include lateral sclerosis and retinitis pigmentosa. An important paralog of this gene is MPP6.
UniProtKB/Swiss-Prot for MPP4 Gene
May play a role in retinal photoreceptors development.