Aliases for MPP3 Gene
External Ids for MPP3 Gene
Previous HGNC Symbols for MPP3 Gene
Previous GeneCards Identifiers for MPP3 Gene
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for MPP3 Gene
MPP3 (Membrane Palmitoylated Protein 3) is a Protein Coding gene. Diseases associated with MPP3 include chromosome 3q29 microdeletion syndrome and allan-herndon-dudley syndrome. Among its related pathways are Transmission across Chemical Synapses and Developmental Biology. GO annotations related to this gene include PDZ domain binding and guanylate kinase activity. An important paralog of this gene is MPP6.