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Aliases for MPHOSPH9 Gene

Aliases for MPHOSPH9 Gene

  • M-Phase Phosphoprotein 9 2 3
  • MPP9 3 4 6
  • MPP-9 3

External Ids for MPHOSPH9 Gene

Summaries for MPHOSPH9 Gene

GeneCards Summary for MPHOSPH9 Gene

MPHOSPH9 (M-Phase Phosphoprotein 9) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPHOSPH9 Gene

Genomics for MPHOSPH9 Gene

Genomic Location for MPHOSPH9 Gene

Start:
123,152,320 bp from pter
End:
123,244,014 bp from pter
Size:
91,695 bases
Orientation:
Minus strand

Genomic View for MPHOSPH9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MPHOSPH9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MPHOSPH9 Gene

Regulatory Elements for MPHOSPH9 Gene

Proteins for MPHOSPH9 Gene

  • Protein details for MPHOSPH9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q99550-MPP9_HUMAN
    Recommended name:
    M-phase phosphoprotein 9
    Protein Accession:
    Q99550
    Secondary Accessions:
    • A1L486
    • A6NEE2
    • B3KR87
    • Q9H976
    • U3KQ28

    Protein attributes for MPHOSPH9 Gene

    Size:
    1183 amino acids
    Molecular mass:
    133024 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14359.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG52299.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=EAW98394.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for MPHOSPH9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MPHOSPH9 Gene

Proteomics data for MPHOSPH9 Gene at MOPED

Post-translational modifications for MPHOSPH9 Gene

No data available for DME Specific Peptides for MPHOSPH9 Gene

Domains for MPHOSPH9 Gene

Protein Domains for MPHOSPH9 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with MPHOSPH9: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MPHOSPH9 Gene

Function for MPHOSPH9 Gene

Phenotypes for MPHOSPH9 Gene

genes like me logo Genes that share phenotypes with MPHOSPH9: view

miRNA for MPHOSPH9 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for MPHOSPH9 Gene

Localization for MPHOSPH9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MPHOSPH9 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus membrane; Peripheral membrane protein. Note=Localizes to the distal and proximal end of centriole pairs in duplicated centrosomes. In ciliated cells, localizes to the distal and proximal end of daughter centriole and proximal of the mother centriole but not in the distal end of the mother centriole.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MPHOSPH9 Gene COMPARTMENTS Subcellular localization image for MPHOSPH9 gene
Compartment Confidence
cytoskeleton 5
golgi apparatus 5
nucleus 4
plasma membrane 4
cytosol 3

Gene Ontology (GO) - Cellular Components for MPHOSPH9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005737 cytoplasm IDA --
GO:0005794 Golgi apparatus IDA 8885239
GO:0005813 centrosome IDA --
GO:0005814 centriole IDA 23644468
genes like me logo Genes that share ontologies with MPHOSPH9: view

Pathways for MPHOSPH9 Gene

SuperPathways for MPHOSPH9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MPHOSPH9 Gene

None

No data available for Pathways by source for MPHOSPH9 Gene

Transcripts for MPHOSPH9 Gene

Unigene Clusters for MPHOSPH9 Gene

M-phase phosphoprotein 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MPHOSPH9 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^
SP1: -
SP2: -
SP3: -
SP4: - -
SP5: - - -
SP6: - - -
SP7: - - - -
SP8:
SP9: -
SP10: -
SP11: -
SP12: - - - -
SP13:
SP14:

ExUns: 19 ^ 20a · 20b ^ 21a · 21b ^ 22 ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28
SP1: - - -
SP2: - - -
SP3: - - - -
SP4: - - -
SP5:
SP6:
SP7:
SP8: - - -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:

Relevant External Links for MPHOSPH9 Gene

GeneLoc Exon Structure for
MPHOSPH9
ECgene alternative splicing isoforms for
MPHOSPH9

Expression for MPHOSPH9 Gene

mRNA expression in normal human tissues for MPHOSPH9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MPHOSPH9 Gene

SOURCE GeneReport for Unigene cluster for MPHOSPH9 Gene Hs.577404

genes like me logo Genes that share expressions with MPHOSPH9: view

Orthologs for MPHOSPH9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MPHOSPH9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MPHOSPH9 36
  • 99.71 (n)
  • 99.32 (a)
MPHOSPH9 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MPHOSPH9 36
  • 87.5 (n)
  • 83.46 (a)
MPHOSPH9 37
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MPHOSPH9 36
  • 88.5 (n)
  • 86.27 (a)
MPHOSPH9 37
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mphosph9 36
  • 79.16 (n)
  • 75.81 (a)
Mphosph9 16
Mphosph9 37
  • 67 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MPHOSPH9 37
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 68 (a)
OneToMany
-- 37
  • 44 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Mphosph9 36
  • 79.76 (n)
  • 77.43 (a)
chicken
(Gallus gallus)
Aves MPHOSPH9 36
  • 68.57 (n)
  • 60.19 (a)
MPHOSPH9 37
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MPHOSPH9 37
  • 47 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mphosph9 36
  • 55.65 (n)
  • 43.4 (a)
zebrafish
(Danio rerio)
Actinopterygii MPHOSPH9 37
  • 38 (a)
OneToOne
Species with no ortholog for MPHOSPH9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MPHOSPH9 Gene

ENSEMBL:
Gene Tree for MPHOSPH9 (if available)
TreeFam:
Gene Tree for MPHOSPH9 (if available)

Paralogs for MPHOSPH9 Gene

Pseudogenes.org Pseudogenes for MPHOSPH9 Gene

genes like me logo Genes that share paralogs with MPHOSPH9: view

No data available for Paralogs for MPHOSPH9 Gene

Variants for MPHOSPH9 Gene

Sequence variations from dbSNP and Humsavar for MPHOSPH9 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs941305 -- 123,230,719(-) CTATG(A/G)ATATG intron-variant
rs941306 -- 123,230,566(-) GCTTT(A/G)GTGGC intron-variant
rs1047158 -- 123,159,509(-) TGTAT(G/T)TTTGG intron-variant, downstream-variant-500B
rs1051431 -- 123,161,256(-) AGCTA(C/T)GAACA reference, synonymous-codon, nc-transcript-variant
rs1051434 -- 123,156,653(+) GTGGC(C/T)ATTTG utr-variant-3-prime, nc-transcript-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MPHOSPH9 Gene

Variant ID Type Subtype PubMed ID
nsv517200 CNV Loss 19592680

Relevant External Links for MPHOSPH9 Gene

HapMap Linkage Disequilibrium report
MPHOSPH9

Disorders for MPHOSPH9 Gene

Relevant External Links for MPHOSPH9

Genetic Association Database (GAD)
MPHOSPH9
Human Genome Epidemiology (HuGE) Navigator
MPHOSPH9
genes like me logo Genes that share disorders with MPHOSPH9: view

No data available for UniProtKB/Swiss-Prot for MPHOSPH9 Gene

Publications for MPHOSPH9 Gene

  1. Identification of novel M phase phosphoproteins by expression cloning. (PMID: 8885239) Matsumoto-Taniura N. … Westendorf J.M. (Mol. Biol. Cell 1996) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score. (PMID: 19879194) De Jager P.L. … Karlson E.W. (Lancet Neurol 2009) 3 49
  4. An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings. (PMID: 20546594) Goldstein B.A. … Barcellos L.F. (BMC Genet. 2010) 3 49
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49

Products for MPHOSPH9 Gene

Sources for MPHOSPH9 Gene

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