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MPHOSPH9 Gene

protein-coding   GIFtS: 52
GCID: GC12M123637

M-Phase Phosphoprotein 9

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
M-Phase Phosphoprotein 91 2
MPP92 3 5
MPP-92

External Ids:    HGNC: 72151   Entrez Gene: 101982   Ensembl: ENSG000000518257   OMIM: 6055015   UniProtKB: Q995503   

Export aliases for MPHOSPH9 gene to outside databases

Previous GC identifers: GC12P122405 GC12M123338 GC12M123445 GC12M122074 GC12M122152 GC12M120601


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MPHOSPH9 Gene:
MPHOSPH9 (M-phase phosphoprotein 9) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MPHOSPH9 gene promoter:
         HFH-3   Elk-1   GATA-3   Lmo2   FOXD3   GATA-1   FOXI1   GATA-6   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MPHOSPH9 promoter sequence
   Search Chromatin IP Primers for MPHOSPH9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MPHOSPH9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24

MPHOSPH9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MPHOSPH9 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M123637:  view genomic region     (about GC identifiers)

Start:
123,636,867 bp from pter      End:
123,728,561 bp from pter
Size:
91,695 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MPP9_HUMAN, Q99550 (See protein sequence)
Recommended Name: M-phase phosphoprotein 9  
Size: 1031 amino acids; 116134 Da
Sequence caution: Sequence=BAB14359.1; Type=Erroneous initiation;
Secondary accessions: A1L486 A6NEE2 B3KR87 Q9H976
Alternative splicing: 2 isoforms:  Q99550-1   Q99550-2   (Incomplete sequence. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MPHOSPH9: NX_Q99550

Explore proteomics data for MPHOSPH9 at MOPED

Post-translational modifications: 

  • Phosphorylated in M (mitotic) phase1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MPHOSPH9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073619.3  
    ENSEMBL proteins: 
     ENSP00000446362   ENSP00000445859   ENSP00000475489   ENSP00000304096   ENSP00000446249  
     ENSP00000475578   ENSP00000441764   ENSP00000475923   ENSP00000475785   ENSP00000440007  
     ENSP00000440664   ENSP00000441298   ENSP00000442663   ENSP00000446334   ENSP00000303597  
     ENSP00000376220  

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    Cloud-Clone Corp. Proteins for MPHOSPH9

     
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    Search eBioscience for ELISAs for MPHOSPH9 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026636 MPHOSPH9

    Graphical View of Domain Structure for InterPro Entry Q99550

    ProtoNet protein and cluster: Q99550


    Find genes that share domains with MPHOSPH9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         3 GenomeRNAi human phenotypes for MPHOSPH9:
     G0/1 arrest  Increased G1 DNA content  Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MPHOSPH9
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    miRNA
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    miRTarBase miRNAs that target MPHOSPH9:
    hsa-mir-130b-3p (MIRT020231), hsa-mir-19b-3p (MIRT031174), hsa-mir-15b-5p (MIRT046416), hsa-mir-340-5p (MIRT019557), hsa-mir-124-3p (MIRT002676)

    Block miRNA regulation of human, mouse, rat MPHOSPH9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MPHOSPH9 (see all 17):
    hsa-miR-3163 hsa-miR-301b hsa-miR-495 hsa-miR-300 hsa-miR-7-2* hsa-miR-381 hsa-miR-301a hsa-miR-3666
    SwitchGear 3'UTR luciferase reporter plasmidMPHOSPH9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MPHOSPH9

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPHOSPH9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MPP9_HUMAN, Q99550: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi
    apparatus membrane; Peripheral membrane protein (Probable). Note=Localizes to the distal and proximal end of
    centriole pairs in duplicated centrosomes. In ciliated cells, localizes to the distal and proximal end of
    daughter centriole and proximal of the mother centriole but not in the distal end of the mother centriole
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    golgi apparatus5
    nucleus4
    plasma membrane4
    cytosol3

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus TAS8885239
    GO:0005813centrosome IDA--

    Find genes that share ontologies with MPHOSPH9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MPHOSPH9
    Interactions:

        Search GeneGlobe Interaction Network for MPHOSPH9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for MPHOSPH9 (Q995502, 3 ENSP000003040964) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAGP619813, ENSP000003063304I2D: score=3 STRING: ENSP00000306330
    USP11P517843, ENSP000002183484I2D: score=2 STRING: ENSP00000218348
    SVILO954253, ENSP000003481284I2D: score=1 STRING: ENSP00000348128
    YWHAZP631043, ENSP000003095034I2D: score=2 STRING: ENSP00000309503
    WNK1Q9H4A33, ENSP000003130594I2D: score=1 STRING: ENSP00000313059
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087mitotic M phase TAS8885239

    Find genes that share ontologies with MPHOSPH9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MPHOSPH9 (MPP9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MPHOSPH9 gene: 
    NM_022782.3  

    Unigene Cluster for MPHOSPH9:

    M-phase phosphoprotein 9
    Hs.577404  [show with all ESTs]
    Unigene Representative Sequence: AK096541
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000544217 ENST00000541603 ENST00000541076(uc001uel.3 uc010tam.2)
    ENST00000606320 ENST00000545974 ENST00000302373 ENST00000545556(uc010tal.2 uc001uem.3)
    ENST00000606704 ENST00000539024 ENST00000536198 ENST00000538250 ENST00000607619
    ENST00000606321 ENST00000541823 ENST00000606326 ENST00000539336 ENST00000537854
    ENST00000539639
    miRNA
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    Block miRNA regulation of human, mouse, rat MPHOSPH9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MPHOSPH9 (see all 17):
    hsa-miR-3163 hsa-miR-301b hsa-miR-495 hsa-miR-300 hsa-miR-7-2* hsa-miR-381 hsa-miR-301a hsa-miR-3666
    SwitchGear 3'UTR luciferase reporter plasmidMPHOSPH9 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MPHOSPH9
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    OriGene ORF clones in mouse, rat for MPHOSPH9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MPHOSPH9 (NM_022782)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MPHOSPH9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MPHOSPH9
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MPHOSPH9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MPHOSPH9
      QuantiTect SYBR Green Assays in human, mouse, rat MPHOSPH9
      QuantiFast Probe-based Assays in human, mouse, rat MPHOSPH9

    Additional mRNA sequence: 

    AK091181.1 AK096541.1 AL096751.1 BC032906.1 BC036600.2 BC130440.1 BC144016.1 BC144017.1 
    X98258.1 

    17 DOTS entries:

    DT.80102030  DT.100024605  DT.91987006  DT.314335  DT.95138518  DT.100024600  DT.40207556  DT.100806639 
    DT.409940  DT.75135112  DT.121108957  DT.121109033  DT.314333  DT.422789  DT.87009098  DT.92421644 
    DT.95331363 

    Selected AceView cDNA sequences (see all 154):

    AW451882 AJ705724 BM802001 BF916900 AL698737 CR610469 AI867901 BM703221 
    X98258 BU783478 AA830355 BM693504 BM314005 AL578631 AA490603 BQ776295 
    BU608455 AK091181 NM_022782 AA306650 AI174329 AI650373 BU070777 AI656864 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MPHOSPH9 (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^
    SP1:                                                                                                                    -                                       
    SP2:                                                                                                              -                                             
    SP3:                                                                                                              -                                             
    SP4:                                                                                                        -     -                                             
    SP5:                                            -     -     -                                                                                                   

    ExUns: 19 ^ 20a · 20b ^ 21a · 21b ^ 22 ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28
    SP1:              -     -                                                     -                     
    SP2:              -     -                                                     -                     
    SP3:              -     -                                   -                 -                     
    SP4:              -     -                             -                                             
    SP5:                                                                                                


    ECgene alternative splicing isoforms for MPHOSPH9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MPHOSPH9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCATCTCTAT
    MPHOSPH9 Expression
    About this image


    MPHOSPH9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Brain (Nervous System)
             Cerebellum
    MPHOSPH9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MPHOSPH9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.577404
        Custom PCR Arrays for MPHOSPH9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MPHOSPH9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MPHOSPH9 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mphosph91 , 5 M-phase phosphoprotein 91, 5 79.16(n)1
    75.81(a)1
      5 (63.47 cM)5
    2697021  NM_001277867.11  NP_001264796.11 
     1242509595 
    chicken
    (Gallus gallus)
    Aves MPHOSPH91 M-phase phosphoprotein 9 68.57(n)
    60.19(a)
      416829  XM_004945538.1  XP_004945595.1 
    lizard
    (Anolis carolinensis)
    Reptilia MPHOSPH96
    M-phase phosphoprotein 9
    47(a)
    1 ↔ 1
    LGb(1877079-1903016)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mphosph91 M-phase phosphoprotein 9 55.65(n)
    43.4(a)
      100037862  XM_004910521.1  XP_004910578.1 
    zebrafish
    (Danio rerio)
    Actinopterygii MPHOSPH96
    M-phase phosphoprotein 9
    38(a)
    1 ↔ 1
    Zv9_NA556(32-3897) ENSDARG00000079091


    ENSEMBL Gene Tree for MPHOSPH9 (if available)
    TreeFam Gene Tree for MPHOSPH9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MPHOSPH9 gene

    Find genes that share paralogs with MPHOSPH9           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for MPHOSPH9
    PGOHUM00000248496


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MPHOSPH9 (see all 1351)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17161631,2
    C,F,H--123640522(-) TGCATG/AGCTTC 1 -- int15Minor allele frequency- A:0.00MN NS EA 600
    rs17273141,2
    C,F,A,H--123640664(-) GGAGGT/GCTCTC 1 -- int110Minor allele frequency- G:0.38NA CSA WA EA 371
    rs1920235491,2
    --123640728(+) TACAAC/TCTCTC 1 -- int10--------
    rs1846244921,2
    --123640843(+) GACACA/GTTTCA 1 -- int10--------
    rs17273131,2
    C,F,A,H--123640853(-) AATTCC/GTATTT 1 -- int129Minor allele frequency- G:0.11NS EA NA WA CSA 2772
    rs563157221,2
    C,F--123640870(+) TCATTG/TTTTAA 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1391766521,2
    --123640943(+) GTCTAC/TCATTA 1 -- int10--------
    rs1903699421,2
    --123641076(+) TCCTCC/TGTTTA 1 -- ut310--------
    rs10514341,2
    C,F,A,H--123641200(+) GTGGCT/CATTTG 1 -- ut31 ese315Minor allele frequency- C:0.38MN NS EA NA 1726
    rs1440694231,2
    C--123641239(+) CATGAC/TTGTAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MPHOSPH9 (123636867 - 123728561 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MPHOSPH9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv517200CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MPHOSPH9
    DNA2.0 Custom Variant and Variant Library Synthesis for MPHOSPH9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605501    OMIM disorders: --


    Find genes that share disorders with MPHOSPH9           About GenesLikeMe

    Genetic Association Database (GAD): MPHOSPH9
    Human Genome Epidemiology (HuGE) Navigator: MPHOSPH9 (6 documents)

    Export disorders for MPHOSPH9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MPHOSPH9 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with MPHOSPH9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel M phase phosphoproteins by expression cloning. (PubMed id 8885239)1, 2, 3 Matsumoto-Taniura N....Westendorf J.M. (Mol. Biol. Cell 1996)
    2. An application of Random Forests to a genome-wide association dataset: methodological considerations &amp; new findings. (PubMed id 20546594)1, 4 Goldstein B.A....Barcellos L.F. (BMC Genet. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score. (PubMed id 19879194)1, 4 De Jager P.L....Karlson E.W. (Lancet Neurol 2009)
    5. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. (PubMed id 19525953)1, 4 De Jager P.L....Oksenberg J.R. (Nat. Genet. 2009)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    8. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    9. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PubMed id 21399614)2 Jakobsen L.... Andersen J.S. (EMBO J. 2011)
    10. Aggregation of multiple sclerosis genetic risk variants in multiple and single case families. (PubMed id 21280076)4 Gourraud P.A....Oksenberg J.R. (Ann. Neurol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10198 HGNC: 7215 AceView: MPHOSPH9 Ensembl:ENSG00000051825 euGenes: HUgn10198
    ECgene: MPHOSPH9 H-InvDB: MPHOSPH9

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MPHOSPH9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MPHOSPH9 gene:
    Search GeneIP for patents involving MPHOSPH9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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