Aliases for MPHOSPH8 Gene
Aliases for MPHOSPH8 Gene
External Ids for MPHOSPH8 Gene
- HGNC: 29810
- Entrez Gene: 54737
- Ensembl: ENSG00000196199
- OMIM: 611626
- UniProtKB: Q99549
Previous GeneCards Identifiers for MPHOSPH8 Gene
- GC13P019107
- GC13P020208
- GC13P001012
Summaries for MPHOSPH8 Gene
GeneCards Summary for MPHOSPH8 Gene
MPHOSPH8 (M-Phase Phosphoprotein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include methylated histone binding.
UniProtKB/Swiss-Prot for MPHOSPH8 Gene
-
Heterochromatin component that specifically recognizes and binds methylated Lys-9 of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3 (PubMed:26022416). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592).
Additional gene information for MPHOSPH8 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPHOSPH8 Gene
Genomics for MPHOSPH8 Gene
GeneHancer (GH) Regulatory Elements for MPHOSPH8 Gene
Regulatory Element Products
Genomic Locations for MPHOSPH8 Gene
- chr13:19,633,647-19,673,459
- (GRCh38/hg38)
- Size:
- 39,813 bases
- Orientation:
- Plus strand
- chr13:20,207,788-20,247,599
- (GRCh37/hg19)
Genomic View for MPHOSPH8 Gene
- Cytogenetic band:
-
- 13q12.11 by Ensembl
- 13q12.11 by Entrez Gene
- 13q12.11 by HGNC


RefSeq DNA sequence for MPHOSPH8 Gene
Proteins for MPHOSPH8 Gene
-
Protein details for MPHOSPH8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99549-MPP8_HUMAN
- Recommended name:
- M-phase phosphoprotein 8
- Protein Accession:
- Q99549
- B7Z6F9
- Q5JPE5
- Q5JTQ0
- Q86TK3
- Q96MK4
- Q9BTP1
Protein attributes for MPHOSPH8 Gene
- Size:
- 860 amino acids
- Molecular mass:
- 97182 Da
- Quaternary structure:
-
- Homodimer (PubMed:21419134, PubMed:22022377, PubMed:22086334). Interacts (via chromo domain) with histone H3K9me3 (PubMed:20871592). Has the highest affinity for H3K9me3, and lesser affinity for H3K9me2 and H3K9me1 (PubMed:20871592). Component of the HUSH complex; at least composed of FAM208A/TASOR, PPHLN1 and MPHOSPH8 (PubMed:26022416). Interacts with DNMT3, EHMT1 and SETDB1 (PubMed:20871592, PubMed:22086334).
- SequenceCaution:
-
- Sequence=AAH46214.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB71284.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI46172.1; Type=Frameshift; Positions=248, 255, 731; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for MPHOSPH8 Gene
Protein Expression for MPHOSPH8 Gene
Post-translational modifications for MPHOSPH8 Gene
- Phosphorylated in M (mitotic) phase. Phosphorylation by CDK1 promotes dissociation from chromatin.
- Ubiquitination at Lys708
Other Protein References for MPHOSPH8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MPHOSPH8
-
Abcam antibodies for MPHOSPH8
- Invitrogen Antibodies for MPHOSPH8
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-
Santa Cruz Biotechnology (SCBT) Antibodies for MPHOSPH8
Protein Products
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OriGene Purified Proteins for MPHOSPH8
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- Compare Top MPHOSPH8 Proteins
-
Quality Products:
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-
Abcam proteins for MPHOSPH8
Assay Products
No data available for DME Specific Peptides for MPHOSPH8 Gene
Domains & Families for MPHOSPH8 Gene
Gene Families for MPHOSPH8 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MPHOSPH8 Gene
Suggested Antigen Peptide Sequences for MPHOSPH8 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q99549UniProtKB/Swiss-Prot:
MPP8_HUMAN :- The chromo domain mediates interaction with methylated Lys-9 of histone H3 (H3K9me), with the highest affinity for the trimethylated form (H3K9me3).
- Domain:
-
- The chromo domain mediates interaction with methylated Lys-9 of histone H3 (H3K9me), with the highest affinity for the trimethylated form (H3K9me3).
Function for MPHOSPH8 Gene
Molecular function for MPHOSPH8 Gene
- UniProtKB/Swiss-Prot Function:
- Heterochromatin component that specifically recognizes and binds methylated Lys-9 of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3 (PubMed:26022416). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592).
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004842 | ubiquitin-protein transferase activity | IBA | -- |
GO:0005515 | protein binding | IPI | 20871592 |
GO:0031625 | ubiquitin protein ligase binding | IBA | -- |
GO:0035064 | methylated histone binding | IDA | 20871592 |
Phenotypes for MPHOSPH8 Gene
Animal Model Products
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-
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CRISPR Products
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miRNA for MPHOSPH8 Gene
- miRTarBase miRNAs that target MPHOSPH8
-
- hsa-mir-26b-5p (MIRT030337)
- hsa-mir-20a-5p (MIRT050509)
- hsa-mir-545-3p (MIRT646309)
- hsa-mir-216b-3p (MIRT646310)
- hsa-mir-7843-5p (MIRT646311)
- hsa-mir-6879-5p (MIRT646312)
- hsa-mir-6735-5p (MIRT646313)
- hsa-mir-4632-5p (MIRT646314)
- hsa-mir-4436b-3p (MIRT646315)
- hsa-mir-1273e (MIRT663229)
- hsa-mir-6516-5p (MIRT663230)
- hsa-mir-455-3p (MIRT663231)
- hsa-mir-650 (MIRT663232)
- hsa-mir-3612 (MIRT663233)
- hsa-mir-4327 (MIRT663234)
- hsa-mir-6499-3p (MIRT663235)
- hsa-mir-4722-5p (MIRT663236)
- hsa-mir-1827 (MIRT663237)
- hsa-mir-4649-3p (MIRT663238)
- hsa-mir-6840-3p (MIRT663239)
- hsa-mir-665 (MIRT663240)
- hsa-mir-4459 (MIRT663241)
- hsa-mir-4768-3p (MIRT663242)
- hsa-mir-6500-3p (MIRT663243)
- hsa-mir-3614-5p (MIRT663244)
- hsa-mir-940 (MIRT663245)
- hsa-mir-6893-5p (MIRT663246)
- hsa-mir-6808-5p (MIRT663247)
- hsa-mir-6511a-5p (MIRT663248)
- hsa-mir-4695-5p (MIRT663249)
- hsa-mir-34b-3p (MIRT663250)
- hsa-mir-4503 (MIRT786026)
- hsa-mir-6792-5p (MIRT788755)
- hsa-mir-7856-5p (MIRT789612)
miRNA Products
- Search ViGene Biosciences for MPHOSPH8
Inhibitory RNA Products
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for MPHOSPH8
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MPHOSPH8 Gene
Localization for MPHOSPH8 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MPHOSPH8 Gene
- Nucleus. Chromosome. Note=Detected on heterochromatin (PubMed:20871592, PubMed:26022416). Dissociates from chromatin during interphase and early mitosis (PubMed:23416073). Detected on nucleosomes (PubMed:20871592). {ECO:0000269 PubMed:20871592, ECO:0000269 PubMed:23416073, ECO:0000269 PubMed:26022416}.
- Nucleus (3)
- Cytosol (1)
- Plasma membrane (1)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000151 | ubiquitin ligase complex | IBA | -- |
GO:0000788 | nuclear nucleosome | IDA | 20871592 |
GO:0005634 | nucleus | IDA | 8885239 |
GO:0005694 | chromosome | IEA | -- |
GO:0005720 | nuclear heterochromatin | IDA | 20871592 |
Pathways & Interactions for MPHOSPH8 Gene
Interacting Proteins for MPHOSPH8 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0016567 | protein ubiquitination | IEA | -- |
GO:0044030 | regulation of DNA methylation | IMP | 20871592 |
GO:0045892 | negative regulation of transcription, DNA-templated | IMP | 20871592 |
No data available for Pathways by source and SIGNOR curated interactions for MPHOSPH8 Gene
Transcripts for MPHOSPH8 Gene
mRNA/cDNA for MPHOSPH8 Gene
- (2) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (246) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MPHOSPH8 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MPHOSPH8
- genomics-online: gRNA clones - Search results for available MPHOSPH8 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPHOSPH8
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miRNA Products
- Search ViGene Biosciences for MPHOSPH8
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for MPHOSPH8
- Browse OriGene Inhibitory RNA Products For MPHOSPH8
- genomics-online: shRNA clones - Search results for available MPHOSPH8 gene related products
-
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Clone Products
-
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- VectorBuilder custom plasmid, inducible vectors for MPHOSPH8
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MPHOSPH8
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MPHOSPH8
- genomics-online: cdna clones - Search results for available MPHOSPH8 gene related products
- orf clones - Search results for available MPHOSPH8 gene related products
- Applied Biological Materials Clones for MPHOSPH8
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
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SP5: |
Expression for MPHOSPH8 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MPHOSPH8 Gene
NURSA nuclear receptor signaling pathways regulating expression of MPHOSPH8 Gene:
MPHOSPH8SOURCE GeneReport for Unigene cluster for MPHOSPH8 Gene:
Hs.269654Evidence on tissue expression from TISSUES for MPHOSPH8 Gene
- Nervous system(4.6)
- Liver(4.3)
- Lymph node(4.3)
- Pancreas(4.3)
- Blood(4.2)
- Intestine(3.6)
- Spleen(2.1)
Primer Products
-
OriGene qPCR primer pairs for MPHOSPH8
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MPHOSPH8 Gene
Orthologs for MPHOSPH8 Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | MPHOSPH8 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | MPHOSPH8 33 |
|
||
cow (Bos Taurus) |
Mammalia | MPHOSPH8 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Mphosph8 33 |
|
||
mouse (Mus musculus) |
Mammalia | Mphosph8 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | MPHOSPH8 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | MPHOSPH8 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | MPHOSPH8 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | MPHOSPH8 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | mphosph8 33 |
|
||
Str.2500 33 |
|
||||
zebrafish (Danio rerio) |
Actinopterygii | mphosph8 34 |
|
OneToOne | |
wufc38d04 33 |
|
||||
rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4384 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany |
- Species where no ortholog for MPHOSPH8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for MPHOSPH8 Gene
(3) SIMAP similar genes for MPHOSPH8 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for MPHOSPH8 Gene
No data available for Paralogs for MPHOSPH8 Gene
Variants for MPHOSPH8 Gene
SNP ID | Clin | Chr 13 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000077422 | -- | 19,672,533(+) | T/C | 3_prime_UTR_variant, genic_downstream_transcript_variant, non_coding_transcript_variant | |
rs1000197650 | -- | 19,646,752(+) | T/C | coding_sequence_variant, non_coding_transcript_variant, synonymous_variant | |
rs1000457086 | -- | 19,649,917(+) | T/C | intron_variant | |
rs1000509589 | -- | 19,656,373(+) | A/C | intron_variant | |
rs1000580413 | -- | 19,655,045(+) | A/T | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1607n100 | CNV | gain | 25217958 |
dgv1608n100 | CNV | gain | 25217958 |
dgv334e199 | CNV | deletion | 23128226 |
esv2747051 | CNV | deletion | 23290073 |
esv2761244 | CNV | gain | 21179565 |
esv3582126 | CNV | gain | 25503493 |
esv3582138 | CNV | gain | 25503493 |
esv3631393 | CNV | gain | 21293372 |
esv3631396 | CNV | gain | 21293372 |
esv3631398 | CNV | gain | 21293372 |
esv3892298 | CNV | gain | 25118596 |
esv3892299 | CNV | gain | 25118596 |
nsv1041042 | CNV | gain | 25217958 |
nsv1047555 | CNV | loss | 25217958 |
nsv1051666 | CNV | gain | 25217958 |
nsv1054226 | CNV | gain | 25217958 |
nsv1078303 | OTHER | inversion | 25765185 |
nsv1115628 | CNV | deletion | 24896259 |
nsv1140246 | OTHER | inversion | 24896259 |
nsv1148310 | CNV | deletion | 26484159 |
nsv1151909 | OTHER | inversion | 26484159 |
nsv516945 | CNV | gain+loss | 19592680 |
nsv977201 | CNV | duplication | 23825009 |
Additional Variant Information for MPHOSPH8 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MPHOSPH8 Gene
Disorders for MPHOSPH8 Gene
Additional Disease Information for MPHOSPH8
No disorders were found for MPHOSPH8 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MPHOSPH8 Gene
Publications for MPHOSPH8 Gene
- Identification of novel M phase phosphoproteins by expression cloning. (PMID: 8885239) Matsumoto-Taniura N … Westendorf JM (Molecular biology of the cell 1996) 2 3 4 58
- GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. (PMID: 26022416) Tchasovnikarova IA … Lehner PJ (Science (New York, N.Y.) 2015) 3 4 58
- Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation. (PMID: 23416073) Nishigaki M … Nakanishi M (Biochemical and biophysical research communications 2013) 3 4 58
- MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. (PMID: 22086334) Chang Y … Cheng X (Nature communications 2011) 3 4 58
- Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9. (PMID: 22022377) Li J … Zang J (PloS one 2011) 3 4 58
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- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for MPHOSPH8
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for MPHOSPH8
- VectorBuilder custom plasmid, inducible vectors for MPHOSPH8
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MPHOSPH8
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MPHOSPH8
- antibodies-online: Search results for 18 available MPHOSPH8 Antibodies ranked by validation data
- Compare Top MPHOSPH8 Antibodies
- antibodies-online: Search results for available MPHOSPH8 related products ranked by validation data
- antibodies-online: Search results for 4 available MPHOSPH8 Proteins ranked by validation data
- Compare Top MPHOSPH8 Proteins
- Quality Products:
- Search GeneTex for Antibodies for MPHOSPH8
- Search GeneTex for Proteins for MPHOSPH8
- ViGene Biosciences adenoviral particle packaged cDNA for MPHOSPH8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for MPHOSPH8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
- Search ViGene Biosciences for MPHOSPH8
- Santa Cruz Biotechnology (SCBT) Antibodies for MPHOSPH8
- Search Santa Cruz Biotechnology (SCBT) for MPHOSPH8 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MPHOSPH8
- Horizon Cell Lines for MPHOSPH8
- genomics-online: cdna clones - Search results for available MPHOSPH8 gene related products
- orf clones - Search results for available MPHOSPH8 gene related products
- genomics-online: gRNA clones - Search results for available MPHOSPH8 gene related products
- genomics-online: primer clones - Search results for available MPHOSPH8 gene related products
- genomics-online: shRNA clones - Search results for available MPHOSPH8 gene related products
Sources for MPHOSPH8 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew