Aliases for MPHOSPH8 Gene
Aliases for MPHOSPH8 Gene
External Ids for MPHOSPH8 Gene
- HGNC: 29810
- Entrez Gene: 54737
- Ensembl: ENSG00000196199
- OMIM: 611626
- UniProtKB: Q99549
Previous GeneCards Identifiers for MPHOSPH8 Gene
- GC13P019107
- GC13P020208
- GC13P001012
Summaries for MPHOSPH8 Gene
GeneCards Summary for MPHOSPH8 Gene
MPHOSPH8 (M-Phase Phosphoprotein 8) is a Protein Coding gene. GO annotations related to this gene include methylated histone binding.
UniProtKB/Swiss-Prot for MPHOSPH8 Gene
-
Heterochromatin component that specifically recognizes and binds methylated Lys-9 of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3 (PubMed:26022416). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592).
No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPHOSPH8 Gene
Genomics for MPHOSPH8 Gene
Regulatory Elements for MPHOSPH8 Gene
Enhancers for MPHOSPH8 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around MPHOSPH8 on UCSC Golden Path with GeneCards custom track
Promoters for MPHOSPH8 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around MPHOSPH8 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the MPHOSPH8 gene promoter:
Regulatory Element Products
Genomic Location for MPHOSPH8 Gene
- Chromosome:
- 13
- Start:
- 19,633,647 bp from pter
- End:
- 19,673,459 bp from pter
- Size:
- 39,813 bases
- Orientation:
- Plus strand
Genomic View for MPHOSPH8 Gene
Genes around MPHOSPH8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q12.11 by Ensembl
- 13q12.11 by Entrez Gene
- 13q12.11 by HGNC
MPHOSPH8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MPHOSPH8 Gene
Proteins for MPHOSPH8 Gene
-
Protein details for MPHOSPH8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99549-MPP8_HUMAN
- Recommended name:
- M-phase phosphoprotein 8
- Protein Accession:
- Q99549
- B7Z6F9
- Q5JPE5
- Q5JTQ0
- Q86TK3
- Q96MK4
- Q9BTP1
Protein attributes for MPHOSPH8 Gene
- Size:
- 860 amino acids
- Molecular mass:
- 97182 Da
- Quaternary structure:
-
- Homodimer (PubMed:21419134, PubMed:22022377, PubMed:22086334). Interacts (via chromo domain) with histone H3K9me3 (PubMed:20871592). Has the highest affinity for H3K9me3, and lesser affinity for H3K9me2 and H3K9me1 (PubMed:20871592). Component of the HUSH complex; at least composed of FAM208A/TASOR, PPHLN1 and MPHOSPH8 (PubMed:26022416). Interacts with DNMT3, EHMT1 and SETDB1 (PubMed:20871592, PubMed:22086334).
- SequenceCaution:
-
- Sequence=AAH46214.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB71284.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI46172.1; Type=Frameshift; Positions=248, 255, 731; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for MPHOSPH8 Gene
Protein Expression for MPHOSPH8 Gene
Post-translational modifications for MPHOSPH8 Gene
- Phosphorylated in M (mitotic) phase. Phosphorylation by CDK1 promotes dissociation from chromatin.
- Ubiquitination at Lys 708
- Modification sites at PhosphoSitePlus
Other Protein References for MPHOSPH8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for MPHOSPH8
- Novus Biologicals Antibodies for MPHOSPH8
- antibodies-online Antibodies for MPHOSPH8: See all 15
- Search GeneTex for Antibodies for MPHOSPH8
-
Santa Cruz Biotechnology (SCBT) Antibodies for MPHOSPH8
Protein Products
-
OriGene Purified Proteins for MPHOSPH8
- Search Origene for MassSpec and Protein Over-expression Lysates for MPHOSPH8
- Origene Custom Protein Services for MPHOSPH8
- antibodies-online Proteins for MPHOSPH8: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for MPHOSPH8
Assay Products
No data available for DME Specific Peptides for MPHOSPH8 Gene
Domains & Families for MPHOSPH8 Gene
Gene Families for MPHOSPH8 Gene
Protein Domains for MPHOSPH8 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MPHOSPH8 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q99549UniProtKB/Swiss-Prot:
MPP8_HUMAN :- The chromo domain mediates interaction with methylated Lys-9 of histone H3 (H3K9me), with the highest affinity for the trimethylated form (H3K9me3).
- Contains 4 ANK repeats.
- Domain:
-
- The chromo domain mediates interaction with methylated Lys-9 of histone H3 (H3K9me), with the highest affinity for the trimethylated form (H3K9me3).
- Contains 1 chromo domain.
- Similarity:
-
- Contains 4 ANK repeats.
Function for MPHOSPH8 Gene
Molecular function for MPHOSPH8 Gene
- UniProtKB/Swiss-Prot Function:
- Heterochromatin component that specifically recognizes and binds methylated Lys-9 of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416). Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3 (PubMed:26022416). Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592). Mediates down-regulation of CDH1 expression (PubMed:20871592).
Phenotypes for MPHOSPH8 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for MPHOSPH8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
- Search ViGene Biosciences for MPHOSPH8
CRISPR Products
-
OriGene CRISPR knockouts for MPHOSPH8
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPHOSPH8
- GenScript: Design CRISPR guide RNA sequences for MPHOSPH8
miRNA for MPHOSPH8 Gene
- miRTarBase miRNAs that target MPHOSPH8
-
- hsa-mir-26b-5p (MIRT030337)
- hsa-mir-20a-5p (MIRT050509)
- hsa-mir-545-3p (MIRT646309)
- hsa-mir-216b-3p (MIRT646310)
- hsa-mir-7843-5p (MIRT646311)
- hsa-mir-6879-5p (MIRT646312)
- hsa-mir-6735-5p (MIRT646313)
- hsa-mir-4632-5p (MIRT646314)
- hsa-mir-4436b-3p (MIRT646315)
- hsa-mir-1273e (MIRT663229)
- hsa-mir-6516-5p (MIRT663230)
- hsa-mir-455-3p (MIRT663231)
- hsa-mir-650 (MIRT663232)
- hsa-mir-3612 (MIRT663233)
- hsa-mir-4327 (MIRT663234)
- hsa-mir-6499-3p (MIRT663235)
- hsa-mir-4722-5p (MIRT663236)
- hsa-mir-1827 (MIRT663237)
- hsa-mir-4649-3p (MIRT663238)
- hsa-mir-6840-3p (MIRT663239)
- hsa-mir-665 (MIRT663240)
- hsa-mir-4459 (MIRT663241)
- hsa-mir-4768-3p (MIRT663242)
- hsa-mir-6500-3p (MIRT663243)
- hsa-mir-3614-5p (MIRT663244)
- hsa-mir-940 (MIRT663245)
- hsa-mir-6893-5p (MIRT663246)
- hsa-mir-6808-5p (MIRT663247)
- hsa-mir-6511a-5p (MIRT663248)
- hsa-mir-4695-5p (MIRT663249)
- hsa-mir-34b-3p (MIRT663250)
miRNA Products
- Search ViGene Biosciences for MPHOSPH8
Clone Products
- OriGene clones in human for MPHOSPH8
- OriGene ORF clones in human,mouse,rat for MPHOSPH8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for MPHOSPH8
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for MPHOSPH8 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MPHOSPH8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MPHOSPH8 Gene
Localization for MPHOSPH8 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MPHOSPH8 Gene
- Nucleus. Chromosome. Note=Detected on heterochromatin (PubMed:20871592, PubMed:26022416). Dissociates from chromatin during interphase and early mitosis (PubMed:23416073). Detected on nucleosomes (PubMed:20871592). {ECO:0000269 PubMed:20871592, ECO:0000269 PubMed:23416073, ECO:0000269 PubMed:26022416}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| plasma membrane | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000788 | nuclear nucleosome | IDA | 20871592 |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0005737 | cytoplasm | IDA | 8885239 |
| GO:0070062 | extracellular exosome | IDA | 23376485 |
Pathways & Interactions for MPHOSPH8 Gene
More details on SuperPathways for MPHOSPH8
No Data Available
Interacting Proteins for MPHOSPH8 Gene
Selected Interacting proteins:
Q99549-MPP8_HUMAN
ENSP00000355388
for MPHOSPH8 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0044030 | regulation of DNA methylation | IMP | 20871592 |
No data available for Pathways by source and SIGNOR curated interactions for MPHOSPH8 Gene
Transcripts for MPHOSPH8 Gene
mRNA/cDNA for MPHOSPH8 Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (246) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MPHOSPH8 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MPHOSPH8
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPHOSPH8
- GenScript: Design CRISPR guide RNA sequences for MPHOSPH8
miRNA Products
- Search ViGene Biosciences for MPHOSPH8
Clone Products
- OriGene clones in human for MPHOSPH8
- OriGene ORF clones in human,mouse,rat for MPHOSPH8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for MPHOSPH8
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||
| SP5: |
Expression for MPHOSPH8 Gene
This gene is overexpressed in Testis (14.0), Peripheral blood mononuclear cells (12.1), Heart (7.9), and Pancreas (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MPHOSPH8 Gene
SOURCE GeneReport for Unigene cluster for MPHOSPH8 Gene Hs.269654
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for MPHOSPH8
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MPHOSPH8 Gene
Orthologs for MPHOSPH8 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | MPHOSPH8 35 |
|
||
| MPHOSPH8 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | MPHOSPH8 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Mphosph8 35 |
|
||
| Mphosph8 16 |
|
||||
| Mphosph8 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | MPHOSPH8 35 |
|
||
| MPHOSPH8 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Mphosph8 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MPHOSPH8 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MPHOSPH8 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MPHOSPH8 35 |
|
||
| MPHOSPH8 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | MPHOSPH8 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mphosph8 35 |
|
||
| Str.2500 35 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | wufc38d04 35 |
|
||
| mphosph8 36 |
|
OneToOne | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4384 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany | |
| -- 36 |
|
OneToMany |
- Species with no ortholog for MPHOSPH8:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for MPHOSPH8 Gene
(3) SIMAP similar genes for MPHOSPH8 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for MPHOSPH8 Gene
No data available for Paralogs for MPHOSPH8 Gene
Variants for MPHOSPH8 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs167117 | -- | 19,644,165(-) | ATACA(A/C)ACAGA | intron-variant | |
| rs176796 | -- | 19,644,297(-) | ATATA(G/T)AGGGA | intron-variant | |
| rs417674 | -- | 19,634,254(-) | GCTCC(C/T)TTCAC | intron-variant | |
| rs456149 | -- | 19,640,097(+) | tctta(A/T)aaaaa | intron-variant | |
| rs456229 | -- | 19,647,677(+) | CATTA(A/C/G)CCAGT | intron-variant |
Residual Variation Intolerance Score:
22.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.69;
57.28% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for MPHOSPH8 Gene
- Human Gene Mutation Database (HGMD)
- MPHOSPH8
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MPHOSPH8 Gene
Disorders for MPHOSPH8 Gene
Relevant External Links for MPHOSPH8
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- MPHOSPH8
No disorders were found for MPHOSPH8 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MPHOSPH8 Gene
Publications for MPHOSPH8 Gene
- Identification of novel M phase phosphoproteins by expression cloning. (PMID: 8885239) Matsumoto-Taniura N. … Westendorf J.M. (Mol. Biol. Cell 1996) 2 3 4 67
- Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
- Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis. (PMID: 25660450) Murata K. … Shimada M. (Biochem. Biophys. Res. Commun. 2015) 3
- Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. (PMID: 25693804) Diner B.A. … Cristea I.M. (Mol. Cell Proteomics 2015) 3
- MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition. (PMID: 25870236) Sun L. … Fang J. (EMBO Rep. 2015) 3
Products for MPHOSPH8 Gene
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- Browse R&D Systems for biochemical assays
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- Custom Assay Services
- OriGene Purified Proteins for MPHOSPH8
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- Browse OriGene Inhibitory RNA Products For MPHOSPH8
- OriGene qPCR primer pairs for MPHOSPH8
- OriGene CRISPR knockouts for MPHOSPH8
- OriGene clones in human for MPHOSPH8
- OriGene ORF clones in human,mouse,rat for MPHOSPH8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript Custom Purified and Recombinant Proteins Services for MPHOSPH8
- GenScript Custom Assay Services for MPHOSPH8
- GenScript Custom overexpressing Cell Line Services for MPHOSPH8
- GenScript: Design CRISPR guide RNA sequences for MPHOSPH8
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- CloneReady with Over 120,000 Genes
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- GenScript Custom Peptide Services for MPHOSPH8
- Novus Biologicals Antibodies for MPHOSPH8
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for MPHOSPH8
- antibodies-online Antibodies for MPHOSPH8: See all 15
- Search antibodies-online for kits
- antibodies-online Proteins for MPHOSPH8: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for MPHOSPH8
- Search GeneTex for Proteins for MPHOSPH8
- ViGene Biosciences adenoviral particle packaged cDNA for MPHOSPH8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for MPHOSPH8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for MPHOSPH8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MPHOSPH8 gene
- Search ViGene Biosciences for MPHOSPH8
- Search ViGene Biosciences for MPHOSPH8
- Santa Cruz Biotechnology (SCBT) Antibodies for MPHOSPH8
- Search Santa Cruz Biotechnology (SCBT) for MPHOSPH8 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MPHOSPH8
Sources for MPHOSPH8 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
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