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Aliases for MPC1L Gene

Aliases for MPC1L Gene

  • Mitochondrial Pyruvate Carrier 1-Like 2 3 5

External Ids for MPC1L Gene

Previous GeneCards Identifiers for MPC1L Gene

  • GC0XP040485

Summaries for MPC1L Gene

GeneCards Summary for MPC1L Gene

MPC1L (Mitochondrial Pyruvate Carrier 1-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPC1L Gene

Genomics for MPC1L Gene

Genomic Location for MPC1L Gene

Chromosome:
X
Start:
40,617,505 bp from pter
End:
40,624,139 bp from pter
Size:
6,635 bases
Orientation:
Plus strand

Genomic View for MPC1L Gene

Genes around MPC1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MPC1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MPC1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MPC1L Gene

No data available for Regulatory Elements for MPC1L Gene

Proteins for MPC1L Gene

  • Protein details for MPC1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0DKB6-MPC1L_HUMAN
    Recommended name:
    Mitochondrial pyruvate carrier 1-like protein
    Protein Accession:
    P0DKB6

    Protein attributes for MPC1L Gene

    Size:
    136 amino acids
    Molecular mass:
    15138 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MPC1L Gene

Proteomics data for MPC1L Gene at MOPED

Post-translational modifications for MPC1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MPC1L Gene

REFSEQ proteins:

No data available for DME Specific Peptides for MPC1L Gene

Domains & Families for MPC1L Gene

Protein Domains for MPC1L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P0DKB6

UniProtKB/Swiss-Prot:

MPC1L_HUMAN :
  • Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
Family:
  • Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
genes like me logo Genes that share domains with MPC1L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for MPC1L Gene

Function for MPC1L Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MPC1L Gene

Localization for MPC1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MPC1L Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MPC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
genes like me logo Genes that share ontologies with MPC1L: view

No data available for Subcellular locations from COMPARTMENTS for MPC1L Gene

Pathways & Interactions for MPC1L Gene

SuperPathways for MPC1L Gene

No Data Available

Interacting Proteins for MPC1L Gene

Gene Ontology (GO) - Biological Process for MPC1L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MPC1L Gene

Drugs & Compounds for MPC1L Gene

No Compound Related Data Available

Transcripts for MPC1L Gene

mRNA/cDNA for MPC1L Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MPC1L Gene

Mitochondrial pyruvate carrier 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MPC1L Gene

No ASD Table

Relevant External Links for MPC1L Gene

GeneLoc Exon Structure for
MPC1L
ECgene alternative splicing isoforms for
MPC1L

Expression for MPC1L Gene

mRNA expression in normal human tissues for MPC1L Gene

mRNA differential expression in normal tissues according to GTEx for MPC1L Gene

This gene is overexpressed in Testis (x52.0).

SOURCE GeneReport for Unigene cluster for MPC1L Gene Hs.128084

genes like me logo Genes that share expression patterns with MPC1L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MPC1L Gene

Orthologs for MPC1L Gene

This gene was present in the common ancestor of mammals.

Orthologs for MPC1L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC520682 35
  • 79.01 (n)
  • 71.3 (a)
dog
(Canis familiaris)
Mammalia MPC1L 35
  • 78.95 (n)
  • 70.18 (a)
rat
(Rattus norvegicus)
Mammalia RGD1563528 35
  • 77.1 (n)
  • 74.75 (a)
Species with no ortholog for MPC1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MPC1L Gene

ENSEMBL:
Gene Tree for MPC1L (if available)
TreeFam:
Gene Tree for MPC1L (if available)

Paralogs for MPC1L Gene

(2) SIMAP similar genes for MPC1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MPC1L: view

No data available for Paralogs for MPC1L Gene

Variants for MPC1L Gene

Sequence variations from dbSNP and Humsavar for MPC1L Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs4261019 -- 40,619,477(+) aaaaa(A/G)gaaac intron-variant
rs2968911 -- 40,621,364(+) CCACC(A/G)CACCC intron-variant
rs2971594 -- 40,621,704(+) TAAGC(A/C)AACAG intron-variant, upstream-variant-2KB
rs2971595 -- 40,621,914(+) CCCTC(C/T)GCAAG intron-variant, upstream-variant-2KB
rs4335278 -- 40,619,556(+) actgt(A/C)caatg intron-variant

Relevant External Links for MPC1L Gene

HapMap Linkage Disequilibrium report
MPC1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MPC1L Gene

Disorders for MPC1L Gene

Relevant External Links for MPC1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MPC1L

No disorders were found for MPC1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MPC1L Gene

Publications for MPC1L Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 67

Products for MPC1L Gene

Sources for MPC1L Gene

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