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Aliases for MPC1L Gene

Aliases for MPC1L Gene

  • Mitochondrial Pyruvate Carrier 1-Like 2 3

External Ids for MPC1L Gene

Previous GeneCards Identifiers for MPC1L Gene

  • GC0XP040485

Summaries for MPC1L Gene

GeneCards Summary for MPC1L Gene

MPC1L (Mitochondrial Pyruvate Carrier 1-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPC1L Gene

Genomics for MPC1L Gene

Genomic Location for MPC1L Gene

40,623,566 bp from pter
40,624,139 bp from pter
574 bases
Plus strand

Genomic View for MPC1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MPC1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MPC1L Gene

No data available for Regulatory Elements for MPC1L Gene

Proteins for MPC1L Gene

  • Protein details for MPC1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Mitochondrial pyruvate carrier 1-like protein
    Protein Accession:
    Secondary Accessions:

    Protein attributes for MPC1L Gene

    136 amino acids
    Molecular mass:
    15138 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MPC1L Gene

Proteomics data for MPC1L Gene at MOPED

Post-translational modifications for MPC1L Gene

No Post-translational modifications

Other Protein References for MPC1L Gene

REFSEQ proteins:

No data available for DME Specific Peptides for MPC1L Gene

Domains for MPC1L Gene

Protein Domains for MPC1L Gene


Graphical View of Domain Structure for InterPro Entry



  • P0DKB6
  • Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
genes like me logo Genes that share domains with MPC1L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for MPC1L Gene

Function for MPC1L Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MPC1L Gene

Localization for MPC1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MPC1L Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MPC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MPC1L: view

No data available for Subcellular locations from COMPARTMENTS for MPC1L Gene

Pathways for MPC1L Gene

SuperPathways for MPC1L Gene

No Data Available

Interacting Proteins for MPC1L Gene

Gene Ontology (GO) - Biological Process for MPC1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006850 mitochondrial pyruvate transport IEA --
genes like me logo Genes that share ontologies with MPC1L: view

No data available for Pathways by source for MPC1L Gene

Transcripts for MPC1L Gene

mRNA/cDNA for MPC1L Gene

(2) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MPC1L Gene

Mitochondrial pyruvate carrier 1-like:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MPC1L

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MPC1L Gene

No ASD Table

Relevant External Links for MPC1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MPC1L Gene

mRNA expression in normal human tissues for MPC1L Gene

mRNA differential expression in normal tissues according to GTEx for MPC1L Gene

This gene is overexpressed in Testis (52.0).

SOURCE GeneReport for Unigene cluster for MPC1L Gene Hs.128084

genes like me logo Genes that share expressions with MPC1L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MPC1L Gene

Orthologs for MPC1L Gene

This gene was present in the common ancestor of mammals.

Orthologs for MPC1L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC520682 35
  • 79.01 (n)
  • 71.3 (a)
(Canis familiaris)
Mammalia MPC1L 35
  • 78.95 (n)
  • 70.18 (a)
(Rattus norvegicus)
Mammalia RGD1563528 35
  • 77.1 (n)
  • 74.75 (a)
Species with no ortholog for MPC1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MPC1L Gene

Gene Tree for MPC1L (if available)
Gene Tree for MPC1L (if available)

Paralogs for MPC1L Gene

Selected SIMAP similar genes for MPC1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MPC1L: view

No data available for Paralogs for MPC1L Gene

Variants for MPC1L Gene

Sequence variations from dbSNP and Humsavar for MPC1L Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2971594 -- 40,621,704(+) TAAGC(A/C)AACAG upstream-variant-2KB
rs5918013 -- 40,621,923(+) AGGTA(A/G)GGAGG upstream-variant-2KB
rs5963823 -- 40,622,142(+) aacaa(A/G)gtgac upstream-variant-2KB
rs6610444 -- 40,621,566(+) TTAAA(A/C)CCTGA upstream-variant-2KB
rs6610445 -- 40,623,047(+) GCAAG(A/G)ATGAG upstream-variant-2KB

Relevant External Links for MPC1L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MPC1L Gene

Disorders for MPC1L Gene

No disorders were found for MPC1L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MPC1L Gene

Publications for MPC1L Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4

Products for MPC1L Gene

Sources for MPC1L Gene

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