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Aliases for MOXD2P Gene

Aliases for MOXD2P Gene

  • Monooxygenase, DBH-Like 2, Pseudogene 2 3 5
  • MOXD2 3 4
  • DBH-Like Monooxygenase Protein 2 Pseudogene 4
  • Dopamine-Beta-Hydroxylase-Like Pseudogene 3
  • Monooxygenase, DBH-Like 2 Pseudogene 2
  • DBH-Like Monooxygenase Protein 2 3
  • EC 1.14.17.- 4

External Ids for MOXD2P Gene

Previous HGNC Symbols for MOXD2P Gene

  • MOXD2

Previous GeneCards Identifiers for MOXD2P Gene

  • GC07M141942

Summaries for MOXD2P Gene

GeneCards Summary for MOXD2P Gene

MOXD2P (Monooxygenase, DBH-Like 2, Pseudogene) is a Pseudogene. GO annotations related to this gene include copper ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOXD2P Gene

Genomics for MOXD2P Gene

Regulatory Elements for MOXD2P Gene

Enhancers for MOXD2P Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MOXD2P on UCSC Golden Path with GeneCards custom track

Genomic Location for MOXD2P Gene

Chromosome:
7
Start:
142,240,737 bp from pter
End:
142,247,067 bp from pter
Size:
6,331 bases
Orientation:
Minus strand

Genomic View for MOXD2P Gene

Genes around MOXD2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MOXD2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MOXD2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOXD2P Gene

Proteins for MOXD2P Gene

  • Protein details for MOXD2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NHM9-MOXD2_HUMAN
    Recommended name:
    Putative DBH-like monooxygenase protein 2
    Protein Accession:
    A6NHM9

    Protein attributes for MOXD2P Gene

    Size:
    499 amino acids
    Molecular mass:
    56320 Da
    Cofactor:
    Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
    Quaternary structure:
    No Data Available

neXtProt entry for MOXD2P Gene

Proteomics data for MOXD2P Gene at MOPED

Post-translational modifications for MOXD2P Gene

  • Glycosylation at Asn 236, Asn 250, Asn 404, and Asn 476

No data available for DME Specific Peptides for MOXD2P Gene

Domains & Families for MOXD2P Gene

Suggested Antigen Peptide Sequences for MOXD2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NHM9

UniProtKB/Swiss-Prot:

MOXD2_HUMAN :
  • Contains 1 DOMON domain.
  • Belongs to the copper type II ascorbate-dependent monooxygenase family.
Domain:
  • Contains 1 DOMON domain.
Family:
  • Belongs to the copper type II ascorbate-dependent monooxygenase family.
genes like me logo Genes that share domains with MOXD2P: view

No data available for Gene Families for MOXD2P Gene

Function for MOXD2P Gene

Enzyme Numbers (IUBMB) for MOXD2P Gene

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MOXD2P Gene

Localization for MOXD2P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MOXD2P Gene

Pathways & Interactions for MOXD2P Gene

SuperPathways for MOXD2P Gene

No Data Available

Interacting Proteins for MOXD2P Gene

Gene Ontology (GO) - Biological Process for MOXD2P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MOXD2P Gene

Drugs & Compounds for MOXD2P Gene

(2) Drugs for MOXD2P Gene - From: ApexBio and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Nepicastat (SYN-117) HCl Pharma Dopamine-β-hydroxylase inhibitor 0
Copper Pharma 161

(1) ApexBio Compounds for MOXD2P Gene

Compound Action Cas Number
Nepicastat (SYN-117) HCl Dopamine-β-hydroxylase inhibitor 170151-24-3
genes like me logo Genes that share compounds with MOXD2P: view

Transcripts for MOXD2P Gene

mRNA/cDNA for MOXD2P Gene

(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MOXD2P Gene

Monooxygenase, DBH-like 2, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MOXD2P Gene

No ASD Table

Relevant External Links for MOXD2P Gene

GeneLoc Exon Structure for
MOXD2P
ECgene alternative splicing isoforms for
MOXD2P

Expression for MOXD2P Gene

mRNA expression in normal human tissues for MOXD2P Gene

mRNA differential expression in normal tissues according to GTEx for MOXD2P Gene

This gene is overexpressed in Testis (x34.6) and Whole Blood (x6.7).

SOURCE GeneReport for Unigene cluster for MOXD2P Gene Hs.641504

genes like me logo Genes that share expression patterns with MOXD2P: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MOXD2P Gene

Orthologs for MOXD2P Gene

Evolution for MOXD2P Gene

ENSEMBL:
Gene Tree for MOXD2P (if available)
TreeFam:
Gene Tree for MOXD2P (if available)

No data available for Orthologs for MOXD2P Gene

Paralogs for MOXD2P Gene

(2) SIMAP similar genes for MOXD2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MOXD2P: view

No data available for Paralogs for MOXD2P Gene

Variants for MOXD2P Gene

Sequence variations from dbSNP and Humsavar for MOXD2P Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs916010 -- 142,247,242(+) GAGAG(A/G)TGCCC upstream-variant-2KB
rs916011 -- 142,247,263(+) CAGGG(A/C)AGGTT upstream-variant-2KB
rs916012 -- 142,247,765(+) AAGAG(A/G)GAGGA upstream-variant-2KB
rs916013 -- 142,247,866(+) ATTAA(C/T)TTAAT upstream-variant-2KB
rs916014 -- 142,248,194(+) AGAAT(C/T)TAGTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MOXD2P Gene

Variant ID Type Subtype PubMed ID
esv33962 CNV Gain+Loss 17666407

Relevant External Links for MOXD2P Gene

HapMap Linkage Disequilibrium report
MOXD2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MOXD2P Gene

Disorders for MOXD2P Gene

Relevant External Links for MOXD2P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MOXD2P

No disorders were found for MOXD2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MOXD2P Gene

Publications for MOXD2P Gene

  1. Inactivation of MOXD2 and S100A15A by exon deletion during human evolution. (PMID: 17642472) Hahn Y. … Lee B. (Mol. Biol. Evol. 2007) 3 4 67
  2. Autoreactive T-cell receptor (Vbeta/D/Jbeta) sequences in diabetes are homologous to insulin, glucagon, the insulin receptor, and the glucagon receptor. (PMID: 19051206) Root-Bernstein R. (J. Mol. Recognit. 2009) 3
  3. An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells. (PMID: 19056690) Van de Walle I. … Taghon T. (Blood 2009) 3
  4. Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire. (PMID: 19380806) Carpenter A.C. … Bassing C.H. (J. Immunol. 2009) 3
  5. Different allelic distribution of a single SNP between sexes in humans. (PMID: 18777093) Tripputi P. … Fedele L. (Biochem. Genet. 2008) 3

Products for MOXD2P Gene

Sources for MOXD2P Gene

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