Aliases for MOV10 Gene
External Ids for MOV10 Gene
Previous GeneCards Identifiers for MOV10 Gene
GeneCards Summary for MOV10 Gene
MOV10 (Mov10 RISC Complex RNA Helicase) is a Protein Coding gene. Among its related pathways are Gene Expression and Signaling by GPCR. GO annotations related to this gene include poly(A) RNA binding and helicase activity. An important paralog of this gene is UPF1.
UniProtKB/Swiss-Prot for MOV10 Gene
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.