Aliases for MOV10 Gene
External Ids for MOV10 Gene
GeneCards Summary for MOV10 Gene
MOV10 (Mov10 RISC Complex RNA Helicase) is a Protein Coding gene. Diseases associated with MOV10 include leukemia. Among its related pathways are PI-3K cascade and PI-3K cascade. GO annotations related to this gene include RNA binding and helicase activity. An important paralog of this gene is UPF1.
UniProtKB/Swiss-Prot for MOV10 Gene
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.