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Aliases for MOSPD2 Gene

Aliases for MOSPD2 Gene

  • Motile Sperm Domain Containing 2 2 3

External Ids for MOSPD2 Gene

Previous GeneCards Identifiers for MOSPD2 Gene

  • GC0XP014253
  • GC0XP014651
  • GC0XP014801
  • GC0XP012649

Summaries for MOSPD2 Gene

GeneCards Summary for MOSPD2 Gene

MOSPD2 (Motile Sperm Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include structural molecule activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOSPD2 Gene

Genomics for MOSPD2 Gene

Regulatory Elements for MOSPD2 Gene

Transcription factor binding sites by QIAGEN in the MOSPD2 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MOSPD2 Gene

Start:
14,873,405 bp from pter
End:
14,922,327 bp from pter
Size:
48,923 bases
Orientation:
Plus strand

Genomic View for MOSPD2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOSPD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOSPD2 Gene

Proteins for MOSPD2 Gene

  • Protein details for MOSPD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHP6-MSPD2_HUMAN
    Recommended name:
    Motile sperm domain-containing protein 2
    Protein Accession:
    Q8NHP6
    Secondary Accessions:
    • Q8N3H2
    • Q8NA83

    Protein attributes for MOSPD2 Gene

    Size:
    518 amino acids
    Molecular mass:
    59746 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MOSPD2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MOSPD2 Gene

Proteomics data for MOSPD2 Gene at MOPED

Post-translational modifications for MOSPD2 Gene

  • Ubiquitination at Lys127
  • Modification sites at PhosphoSitePlus

Other Protein References for MOSPD2 Gene

No data available for DME Specific Peptides for MOSPD2 Gene

Domains for MOSPD2 Gene

Suggested Antigen Peptide Sequences for MOSPD2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NHP6

UniProtKB/Swiss-Prot:

MSPD2_HUMAN :
  • Q8NHP6
Domain:
  • Contains 1 CRAL-TRIO domain.
  • Contains 1 MSP domain.
genes like me logo Genes that share domains with MOSPD2: view

No data available for Gene Families for MOSPD2 Gene

Function for MOSPD2 Gene

Gene Ontology (GO) - Molecular Function for MOSPD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005198 structural molecule activity --
genes like me logo Genes that share ontologies with MOSPD2: view

Animal Model Products

miRNA for MOSPD2 Gene

miRTarBase miRNAs that target MOSPD2

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOSPD2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MOSPD2 Gene

Localization for MOSPD2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MOSPD2 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MOSPD2 Gene COMPARTMENTS Subcellular localization image for MOSPD2 gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for MOSPD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MOSPD2: view

Pathways for MOSPD2 Gene

SuperPathways for MOSPD2 Gene

No Data Available

Interacting Proteins for MOSPD2 Gene

Gene Ontology (GO) - Biological Process for MOSPD2 Gene

None

No data available for Pathways by source for MOSPD2 Gene

Transcripts for MOSPD2 Gene

Unigene Clusters for MOSPD2 Gene

Motile sperm domain containing 2:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOSPD2

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MOSPD2 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b
SP1: - - -
SP2: - -
SP3: - - - - - -
SP4: - -
SP5: -

Relevant External Links for MOSPD2 Gene

GeneLoc Exon Structure for
MOSPD2
ECgene alternative splicing isoforms for
MOSPD2

Expression for MOSPD2 Gene

mRNA expression in normal human tissues for MOSPD2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MOSPD2 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (4.9) and Whole Blood (4.1).

Protein differential expression in normal tissues for MOSPD2 Gene

This gene is overexpressed in Bone (22.6) and Spinal cord (9.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MOSPD2 Gene

SOURCE GeneReport for Unigene cluster for MOSPD2 Gene Hs.744919

genes like me logo Genes that share expressions with MOSPD2: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Expression partners for MOSPD2 Gene

Orthologs for MOSPD2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MOSPD2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MOSPD2 35
  • 89.68 (n)
  • 89.68 (a)
-- 36
  • 79 (a)
OneToMany
MOSPD2 36
  • 87 (a)
OneToMany
dog
(Canis familiaris)
Mammalia MOSPD2 35
  • 92.34 (n)
  • 94.4 (a)
MOSPD2 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mospd2 35
  • 86.94 (n)
  • 89.96 (a)
Mospd2 16
Mospd2 36
  • 90 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MOSPD2 35
  • 99.55 (n)
  • 99.42 (a)
MOSPD2 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mospd2 35
  • 86.79 (n)
  • 89.73 (a)
oppossum
(Monodelphis domestica)
Mammalia MOSPD2 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MOSPD2 36
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves MOSPD2 35
  • 72.42 (n)
  • 71.37 (a)
MOSPD2 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MOSPD2 36
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mospd2 35
  • 67.73 (n)
  • 65.34 (a)
Str.3865 35
zebrafish
(Danio rerio)
Actinopterygii mospd2 35
  • 61.37 (n)
  • 63.81 (a)
wufc48a06 35
mospd2 36
  • 60 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9762 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005556 35
  • 44.57 (n)
  • 33.26 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33523 35
  • 44.99 (n)
  • 30.33 (a)
CG32407 36
  • 28 (a)
OneToMany
CG33523 36
  • 26 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea hpo-28 35
  • 46.03 (n)
  • 31.2 (a)
hpo-28 36
  • 22 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CSR1 38
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
OneToMany
CSA.3857 36
  • 18 (a)
OneToMany
CSA.9460 36
  • 31 (a)
OneToMany
Species with no ortholog for MOSPD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOSPD2 Gene

ENSEMBL:
Gene Tree for MOSPD2 (if available)
TreeFam:
Gene Tree for MOSPD2 (if available)

Paralogs for MOSPD2 Gene

Selected SIMAP similar genes for MOSPD2 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with MOSPD2: view

No data available for Paralogs for MOSPD2 Gene

Variants for MOSPD2 Gene

Sequence variations from dbSNP and Humsavar for MOSPD2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1048685 -- 14,920,005(+) TGATT(A/T)TAAGA utr-variant-3-prime, intron-variant
rs1548385 -- 14,888,192(+) AGAAT(A/G)TATAC intron-variant
rs1858882 -- 14,895,696(+) AACTC(A/G)TCTTA intron-variant
rs1972499 -- 14,888,435(+) CTGGT(C/G)GTTTT intron-variant
rs1989813 -- 14,915,323(+) TAGGT(C/T)GAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MOSPD2 Gene

Variant ID Type Subtype PubMed ID
nsv9934 CNV Loss 18304495
esv272861 CNV Insertion 20981092
esv268644 CNV Insertion 20981092

Relevant External Links for MOSPD2 Gene

HapMap Linkage Disequilibrium report
MOSPD2
Locus Specific Mutation Databases (LSDB)
MOSPD2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MOSPD2 Gene

Disorders for MOSPD2 Gene

Relevant External Links for MOSPD2

Genetic Association Database (GAD)
MOSPD2

No disorders were found for MOSPD2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MOSPD2 Gene

Publications for MOSPD2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for MOSPD2 Gene

Sources for MOSPD2 Gene

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