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Aliases for MOSPD1 Gene

Aliases for MOSPD1 Gene

  • Motile Sperm Domain Containing 1 2 3 5
  • DJ473B4 3

External Ids for MOSPD1 Gene

Previous GeneCards Identifiers for MOSPD1 Gene

  • GC0XM132728
  • GC0XM133747
  • GC0XM133849
  • GC0XM134021
  • GC0XM123419

Summaries for MOSPD1 Gene

GeneCards Summary for MOSPD1 Gene

MOSPD1 (Motile Sperm Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is MOSPD3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOSPD1 Gene

Genomics for MOSPD1 Gene

Regulatory Elements for MOSPD1 Gene

Enhancers for MOSPD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MOSPD1 on UCSC Golden Path with GeneCards custom track

Promoters for MOSPD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MOSPD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MOSPD1 Gene

134,887,626 bp from pter
134,915,267 bp from pter
27,642 bases
Minus strand

Genomic View for MOSPD1 Gene

Genes around MOSPD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MOSPD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MOSPD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOSPD1 Gene

Proteins for MOSPD1 Gene

  • Protein details for MOSPD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Motile sperm domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RE62
    • D3DTG5
    • Q5H9C5
    • Q5H9C7

    Protein attributes for MOSPD1 Gene

    213 amino acids
    Molecular mass:
    24086 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MOSPD1 Gene


neXtProt entry for MOSPD1 Gene

Proteomics data for MOSPD1 Gene at MOPED

Post-translational modifications for MOSPD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MOSPD1 Gene

Antibody Products

No data available for DME Specific Peptides for MOSPD1 Gene

Domains & Families for MOSPD1 Gene

Protein Domains for MOSPD1 Gene

Suggested Antigen Peptide Sequences for MOSPD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MSP domain.
  • Contains 1 MSP domain.
genes like me logo Genes that share domains with MOSPD1: view

No data available for Gene Families for MOSPD1 Gene

Function for MOSPD1 Gene

Phenotypes for MOSPD1 Gene

MGI mutant phenotypes for MOSPD1:
inferred from 1 alleles
GenomeRNAi human phenotypes for MOSPD1:
genes like me logo Genes that share phenotypes with MOSPD1: view

Animal Models for MOSPD1 Gene

MGI Knock Outs for MOSPD1:

Animal Model Products

miRNA for MOSPD1 Gene

miRTarBase miRNAs that target MOSPD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MOSPD1 Gene

Localization for MOSPD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MOSPD1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MOSPD1 Gene COMPARTMENTS Subcellular localization image for MOSPD1 gene
Compartment Confidence
nucleus 4
plasma membrane 2
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for MOSPD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0048471 perinuclear region of cytoplasm ISS --
genes like me logo Genes that share ontologies with MOSPD1: view

Pathways & Interactions for MOSPD1 Gene

SuperPathways for MOSPD1 Gene

No Data Available

Interacting Proteins for MOSPD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000359819 for MOSPD1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for MOSPD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MOSPD1 Gene

Drugs & Compounds for MOSPD1 Gene

No Compound Related Data Available

Transcripts for MOSPD1 Gene

Unigene Clusters for MOSPD1 Gene

Motile sperm domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MOSPD1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - - - -
SP2: - -
SP3: - - - - - -
SP4: - - - - - -
SP5: -
SP6: - -
SP7: - - -
SP8: - - - - -

Relevant External Links for MOSPD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MOSPD1 Gene

mRNA expression in normal human tissues for MOSPD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MOSPD1 Gene

This gene is overexpressed in Bone (54.3) and Pancreatic juice (8.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for MOSPD1 Gene

SOURCE GeneReport for Unigene cluster for MOSPD1 Gene Hs.590789

genes like me logo Genes that share expression patterns with MOSPD1: view

Protein tissue co-expression partners for MOSPD1 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MOSPD1 Gene

Orthologs for MOSPD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for MOSPD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MOSPD1 35
  • 93.58 (n)
  • 97.18 (a)
  • 97 (a)
(Canis familiaris)
Mammalia LOC481058 35
  • 93.58 (n)
  • 97.18 (a)
  • 97 (a)
(Mus musculus)
Mammalia Mospd1 35
  • 91.71 (n)
  • 97.18 (a)
Mospd1 16
Mospd1 36
  • 97 (a)
(Pan troglodytes)
Mammalia MOSPD1 35
  • 100 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Mospd1 35
  • 92.64 (n)
  • 97.18 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
-- 36
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia MOSPD1 36
  • 88 (a)
(Gallus gallus)
Aves MOSPD1 35
  • 84.35 (n)
  • 90.14 (a)
  • 85 (a)
(Anolis carolinensis)
Reptilia MOSPD1 36
  • 85 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mospd1 35
  • 79.03 (n)
  • 85.45 (a)
Str.17325 35
African clawed frog
(Xenopus laevis)
Amphibia dj473b4-prov 35
(Danio rerio)
Actinopterygii Dr.1753 35
mospd1 35
  • 67.45 (n)
  • 77.83 (a)
mospd1 36
  • 75 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5949 35
(Caenorhabditis elegans)
Secernentea C34D10.1 35
  • 47.08 (n)
  • 39.18 (a)
C34D10.1 36
  • 34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
Species with no ortholog for MOSPD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOSPD1 Gene

Gene Tree for MOSPD1 (if available)
Gene Tree for MOSPD1 (if available)

Paralogs for MOSPD1 Gene

Paralogs for MOSPD1 Gene

(1) SIMAP similar genes for MOSPD1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MOSPD1: view

Variants for MOSPD1 Gene

Sequence variations from dbSNP and Humsavar for MOSPD1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
VAR_036601 A breast cancer sample
rs747723561 -- 134,899,079(+) ATTGA(C/T)CTTGA intron-variant
rs747728859 -- 134,907,452(+) TTCCT(C/G)ATGAT intron-variant
rs747904059 -- 134,896,828(+) GAAAC(A/G)ACTGC reference, missense
rs747920976 -- 134,913,288(+) GAGAT(C/T)GCTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MOSPD1 Gene

Variant ID Type Subtype PubMed ID
nsv507997 CNV Insertion 20534489

Variation tolerance for MOSPD1 Gene

Residual Variation Intolerance Score: 29.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.54; 55.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MOSPD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MOSPD1 Gene

Disorders for MOSPD1 Gene

Relevant External Links for MOSPD1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MOSPD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MOSPD1 Gene

Publications for MOSPD1 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. (PMID: 15533722) Pall G.S. … Forrester L.M. (Genomics 2004) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MOSPD1 Gene

Sources for MOSPD1 Gene