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Aliases for MOSPD1 Gene

Aliases for MOSPD1 Gene

  • Motile Sperm Domain Containing 1 2 3
  • Motile Sperm Domain-Containing Protein 1 3
  • DJ473B4 3

External Ids for MOSPD1 Gene

Previous GeneCards Identifiers for MOSPD1 Gene

  • GC0XM132728
  • GC0XM133747
  • GC0XM133849
  • GC0XM134021
  • GC0XM123419

Summaries for MOSPD1 Gene

GeneCards Summary for MOSPD1 Gene

MOSPD1 (Motile Sperm Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include structural molecule activity. An important paralog of this gene is MOSPD3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOSPD1 Gene

Genomics for MOSPD1 Gene

Regulatory Elements for MOSPD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MOSPD1 Gene

Start:
134,887,626 bp from pter
End:
134,915,267 bp from pter
Size:
27,642 bases
Orientation:
Minus strand

Genomic View for MOSPD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOSPD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOSPD1 Gene

Proteins for MOSPD1 Gene

  • Protein details for MOSPD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJG1-MSPD1_HUMAN
    Recommended name:
    Motile sperm domain-containing protein 1
    Protein Accession:
    Q9UJG1
    Secondary Accessions:
    • B2RE62
    • D3DTG5
    • Q5H9C5
    • Q5H9C7

    Protein attributes for MOSPD1 Gene

    Size:
    213 amino acids
    Molecular mass:
    24086 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MOSPD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MOSPD1 Gene

Proteomics data for MOSPD1 Gene at MOPED

Post-translational modifications for MOSPD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MOSPD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MOSPD1 Gene

Domains for MOSPD1 Gene

Protein Domains for MOSPD1 Gene

Suggested Antigen Peptide Sequences for MOSPD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UJG1

UniProtKB/Swiss-Prot:

MSPD1_HUMAN :
  • Q9UJG1
Domain:
  • Contains 1 MSP domain.
genes like me logo Genes that share domains with MOSPD1: view

No data available for Gene Families for MOSPD1 Gene

Function for MOSPD1 Gene

Gene Ontology (GO) - Molecular Function for MOSPD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005198 structural molecule activity --
genes like me logo Genes that share ontologies with MOSPD1: view

Phenotypes for MOSPD1 Gene

GenomeRNAi human phenotypes for MOSPD1:
genes like me logo Genes that share phenotypes with MOSPD1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOSPD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MOSPD1 Gene

Localization for MOSPD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MOSPD1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MOSPD1 Gene COMPARTMENTS Subcellular localization image for MOSPD1 gene
Compartment Confidence
nucleus 3
plasma membrane 2
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for MOSPD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005737 cytoplasm ISS --
GO:0016021 integral component of membrane IEA --
GO:0048471 perinuclear region of cytoplasm ISS --
genes like me logo Genes that share ontologies with MOSPD1: view

Pathways for MOSPD1 Gene

SuperPathways for MOSPD1 Gene

No Data Available

Interacting Proteins for MOSPD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359819%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000359819 for MOSPD1 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for MOSPD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS --
GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS --
genes like me logo Genes that share ontologies with MOSPD1: view

No data available for Pathways by source for MOSPD1 Gene

Transcripts for MOSPD1 Gene

Unigene Clusters for MOSPD1 Gene

Motile sperm domain containing 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOSPD1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MOSPD1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - - - -
SP2: - -
SP3: - - - - - -
SP4: - - - - - -
SP5: -
SP6: - -
SP7: - - -
SP8: - - - - -

Relevant External Links for MOSPD1 Gene

GeneLoc Exon Structure for
MOSPD1
ECgene alternative splicing isoforms for
MOSPD1

Expression for MOSPD1 Gene

mRNA expression in normal human tissues for MOSPD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MOSPD1 Gene

SOURCE GeneReport for Unigene cluster for MOSPD1 Gene Hs.590789

genes like me logo Genes that share expressions with MOSPD1: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MOSPD1 Gene

Orthologs for MOSPD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for MOSPD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MOSPD1 35
  • 100 (n)
  • 100 (a)
MOSPD1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MOSPD1 35
  • 93.58 (n)
  • 97.18 (a)
MOSPD1 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC481058 35
  • 93.58 (n)
  • 97.18 (a)
MOSPD1 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mospd1 35
  • 91.71 (n)
  • 97.18 (a)
Mospd1 16
Mospd1 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia MOSPD1 36
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mospd1 35
  • 92.64 (n)
  • 97.18 (a)
chicken
(Gallus gallus)
Aves MOSPD1 35
  • 84.35 (n)
  • 90.14 (a)
MOSPD1 36
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MOSPD1 36
  • 85 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia dj473b4-prov 35
tropical clawed frog
(Silurana tropicalis)
Amphibia mospd1 35
  • 79.03 (n)
  • 85.45 (a)
Str.17325 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5949 35
zebrafish
(Danio rerio)
Actinopterygii Dr.1753 35
mospd1 35
  • 67.45 (n)
  • 77.83 (a)
mospd1 36
  • 75 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C34D10.1 35
  • 47.08 (n)
  • 39.18 (a)
C34D10.1 36
  • 34 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
OneToMany
Species with no ortholog for MOSPD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOSPD1 Gene

ENSEMBL:
Gene Tree for MOSPD1 (if available)
TreeFam:
Gene Tree for MOSPD1 (if available)

Paralogs for MOSPD1 Gene

Paralogs for MOSPD1 Gene

Selected SIMAP similar genes for MOSPD1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MOSPD1: view

Variants for MOSPD1 Gene

Sequence variations from dbSNP and Humsavar for MOSPD1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1894517 -- 134,901,095(+) TCAAA(C/T)AGGAG intron-variant
rs1984391 -- 134,895,957(+) GAAAT(A/G)AACAT intron-variant
rs2354497 -- 134,917,194(-) gtgga(A/T)cacat upstream-variant-2KB
rs2354498 -- 134,895,338(-) ATTTT(A/G)TTTT intron-variant
rs3795183 -- 134,909,033(+) AAGGC(C/T)GAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MOSPD1 Gene

Variant ID Type Subtype PubMed ID
nsv507997 CNV Insertion 20534489

Relevant External Links for MOSPD1 Gene

HapMap Linkage Disequilibrium report
MOSPD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MOSPD1 Gene

Disorders for MOSPD1 Gene

Relevant External Links for MOSPD1

Genetic Association Database (GAD)
MOSPD1
genes like me logo Genes that share disorders with MOSPD1: view

No data available for UniProtKB/Swiss-Prot for MOSPD1 Gene

Publications for MOSPD1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. (PMID: 15533722) Pall G.S. … Forrester L.M. (Genomics 2004) 2 3
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PMID: 18781797) Meierhofer D. … Kaiser P. (J. Proteome Res. 2008) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for MOSPD1 Gene

Sources for MOSPD1 Gene

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