 |
 | Services
| |
 |
Aliases & Descriptions for MOS
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| EC 2.7.11.1 3 | | MGC119962 2 | | MGC119963 2 | | MSV 2 | | c-mos 3 |
| | | Descriptions |
|---|
| Oocyte maturation factor mos 2, 3 | | oncogene MOS, Moloney murine sarcoma virus 2 | | v-mos Moloney murine sarcoma viral oncogene homolog 2 |
|
| | Search outside databases for aliases for MOS genePrevious GC identifers: GC08M056208 GC08M056964 GC08M056748 GC08M057075 |
Summaries for MOS(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Gene Wiki entry for MOS |
Genomic Location for MOS
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the MOS gene 
Entrez Gene cytogenetic band: 8q11 Ensembl cytogenetic band: 8q12.1 HGNC cytogenetic band: 8q11MOS Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M057188:
(about GC identifiers)
Start:
|
57,188,055 bp from pter |
End:
|
57,189,095 bp from pter |
Size:
|
1,041 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000008.9 NT_008183.18
| Proteins for MOS
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MOS_HUMAN, P00540 (See
protein sequence)Recommended Name: Proto-oncogene serine/threonine-protein kinase mos Size: 346 amino acids; 37820 Da
Secondary accessions: Q3KPG9 Q3KPH0Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_005363.1
ENSEMBL proteins: ENSP00000310722
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for MOS: Assays for MOS: | Protein
Domains/ Families for MOS(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P00540
ProtoNet protein and cluster: P00540 UniProtKB/Swiss-Prot: MOS_HUMAN, P00540Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase familySimilarity: Contains 1 protein kinase domain | Gene Function for MOS
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005372
Applied Biosystems Silencer® siRNAs for MOS
Sigma-Aldrich siRNA and siRNA Panels for MOS  Sigma-Aldrich shRNA Panels and shRNA for MOS  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005372                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_005372                                  untagged cDNA clone in CMV expression vector: NM_005372 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_005372
UniProtKB/Swiss-Prot: MOS_HUMAN, P00540Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme Number (IUBMB): EC 2.7.11.1 Genatlas biochemistry entry for MOS:Moloney murine sarcoma viral (v-mos) oncogene homolog (cytostatic factor blocking cells at metaphase)3 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Mos):
5 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for MOS
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| 1 Sigma-Aldrich "Your Favorite Gene" Pathway for MOS (Your Favorite Gene powered by Ingenuity) 
Gene Network CentralTM Interacting Genes and Proteins Network for MOS 
5/21 Interacting proteins for MOS (P005401 ENSP000003107223) via UniProtKB, MINT, and/or STRING (see all 21
)About this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006468 | protein amino acid phosphorylation |
IEA | -- | About this table
|
Drugs & Compounds for MOS(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for MOS 4 Novoseek chemical compound relationships for MOS gene
About this table
|
Transcripts for MOS(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005372
Sigma-Aldrich siRNA and siRNA Panels for MOS  Sigma-Aldrich shRNA Panels and shRNA for MOS  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_005372 REFSEQ mRNAs for MOS gene: NM_005372.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_005372               OriGene GFP tagged cDNA clone in CMV expression vector: NM_005372                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_005372                                  untagged cDNA clone in CMV expression vector: NM_005372  Additional cDNA sequence: BC069569.1 BC069590.1 BC106737.1 BC106738.1 1 DOTS entry: DT.91811430 4 AceView cDNA sequences:NM_005372 BC069569 BC069590 AY279177
highest scoring ESTs for MOS:BC069569 BC069590 NM_005372 AY279177 BC106737 BC106738 HG1733-HT1748 Unigene Cluster for MOS: V-mos Moloney murine sarcoma viral oncogene homolog Hs.533432 Unigene Representative Sequence: NM_005372
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000311923
|
Expression for MOS
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MOS expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MOS
1 / 2 / 3 3 probe-sets matching MOS gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GAGTTCGGTG
SOURCE GeneReport for Unigene cluster: Hs.533432 UniProtKB/Swiss-Prot: MOS_HUMAN, P00540Tissue specificity: Expressed specifically in testis during spermatogenesis |
Orthologs for MOS
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for MOS gene from 5/10 species (see all 10
)
About this table Species with no ortholog for MOS
ENSEMBL Gene Tree for MOS | Paralogs for MOS(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for MOS gene
- TNNI3K2 ILK2
|
SNPs/Variants for MOS(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for MOS (up to first 250kb)
|
Disorders & Mutations for MOS
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 190060
1 Novoseek disease relationship for MOS gene
| Disease |
Score |
Articles |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0.00 |
2 |
1836123 (1), 8549590 (1) |
About this table
Tumor Gene Database: MOS
|
Medical News for MOS(Possibly Related Articles in
Doctor's Guide)
About This Section
| |
Publications for MOS (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/88 PubMed articles for MOS gene (see all 88
): |
Search for MOS
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MOS
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MOS
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MOS(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for MOS(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for MOS:

 | |
 | | | | |
|
 |  |  |
| | Recombinant Proteins (MOS) | | Antibodies (MOS) |
| | | Search Tocris compounds for MOS |
|
 |
 | | | Antibodies for MOS |
| |
GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
|