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Aliases for MORN5 Gene

Aliases for MORN5 Gene

  • MORN Repeat Containing 5 2 3 5
  • C9orf113 3 4
  • C9orf18 3 4
  • Chromosome 9 Open Reading Frame 113 2
  • Chromosome 9 Open Reading Frame 18 2
  • MORN Repeat-Containing Protein 5 3

External Ids for MORN5 Gene

Previous HGNC Symbols for MORN5 Gene

  • C9orf113
  • C9orf18

Previous GeneCards Identifiers for MORN5 Gene

  • GC09P123963
  • GC09P124922
  • GC09P094536

Summaries for MORN5 Gene

GeneCards Summary for MORN5 Gene

MORN5 (MORN Repeat Containing 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MORN5 Gene

Genomics for MORN5 Gene

Regulatory Elements for MORN5 Gene

Enhancers for MORN5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G122826 1.4 ENCODE dbSUPER 5 +667.8 667794 3.2 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 MORN5 STRBP PDCL GC09M122816
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MORN5 on UCSC Golden Path with GeneCards custom track

Genomic Location for MORN5 Gene

Chromosome:
9
Start:
122,159,858 bp from pter
End:
122,200,088 bp from pter
Size:
40,231 bases
Orientation:
Plus strand

Genomic View for MORN5 Gene

Genes around MORN5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MORN5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MORN5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MORN5 Gene

Proteins for MORN5 Gene

  • Protein details for MORN5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VZ52-MORN5_HUMAN
    Recommended name:
    MORN repeat-containing protein 5
    Protein Accession:
    Q5VZ52
    Secondary Accessions:
    • B7Z7I5
    • Q6ZQN1

    Protein attributes for MORN5 Gene

    Size:
    161 amino acids
    Molecular mass:
    18731 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MORN5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MORN5 Gene

Post-translational modifications for MORN5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MORN5 Gene

Domains & Families for MORN5 Gene

Protein Domains for MORN5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MORN5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MORN5: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MORN5 Gene

Function for MORN5 Gene

genes like me logo Genes that share phenotypes with MORN5: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MORN5 Gene

Localization for MORN5 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MORN5 gene
Compartment Confidence
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MORN5 Gene

Pathways & Interactions for MORN5 Gene

SuperPathways for MORN5 Gene

No Data Available

Interacting Proteins for MORN5 Gene

Gene Ontology (GO) - Biological Process for MORN5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MORN5 Gene

Transcripts for MORN5 Gene

Unigene Clusters for MORN5 Gene

MORN repeat containing 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MORN5 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5
SP1:
SP2: -

Relevant External Links for MORN5 Gene

GeneLoc Exon Structure for
MORN5
ECgene alternative splicing isoforms for
MORN5

Expression for MORN5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MORN5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MORN5 Gene

This gene is overexpressed in Testis (x17.5) and Colon - Sigmoid (x8.2).

Protein differential expression in normal tissues from HIPED for MORN5 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MORN5 Gene



Protein tissue co-expression partners for MORN5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MORN5 Gene:

MORN5

SOURCE GeneReport for Unigene cluster for MORN5 Gene:

Hs.71428
genes like me logo Genes that share expression patterns with MORN5: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MORN5 Gene

Orthologs for MORN5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MORN5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MORN5 34 35
  • 98.96 (n)
dog
(Canis familiaris)
Mammalia MORN5 34 35
  • 85.3 (n)
cow
(Bos Taurus)
Mammalia MORN5 34 35
  • 83.23 (n)
mouse
(Mus musculus)
Mammalia Morn5 34 16 35
  • 80.75 (n)
rat
(Rattus norvegicus)
Mammalia Morn5 34
  • 80.66 (n)
oppossum
(Monodelphis domestica)
Mammalia MORN5 35
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MORN5 35
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves MORN5 34 35
  • 63.54 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia morn5 34
  • 69.36 (n)
Str.15464 34
zebrafish
(Danio rerio)
Actinopterygii morn5 34 35
  • 65.62 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 28 (a)
OneToOne
Species where no ortholog for MORN5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MORN5 Gene

ENSEMBL:
Gene Tree for MORN5 (if available)
TreeFam:
Gene Tree for MORN5 (if available)

Paralogs for MORN5 Gene

(2) SIMAP similar genes for MORN5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with MORN5: view

No data available for Paralogs for MORN5 Gene

Variants for MORN5 Gene

Sequence variations from dbSNP and Humsavar for MORN5 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000009326 -- 122,163,490(+) ATAGT(A/G)TTTGA intron-variant, upstream-variant-2KB
rs1000038008 -- 122,169,919(+) GGCCA(C/G)TCCTC intron-variant
rs1000278827 -- 122,159,820(+) CAACC(A/C)CGAGC upstream-variant-2KB, reference, missense
rs1000479076 -- 122,168,252(+) GTTAG(C/G)TCTTA intron-variant
rs1000638754 -- 122,172,667(+) TGGAT(C/T)GTGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MORN5 Gene

Variant ID Type Subtype PubMed ID
esv3545418 CNV deletion 23714750
nsv1115229 CNV deletion 24896259
nsv472422 CNV novel sequence insertion 20440878
nsv6702 CNV insertion 18451855
nsv831715 CNV gain 17160897

Variation tolerance for MORN5 Gene

Residual Variation Intolerance Score: 65.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.44; 28.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MORN5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MORN5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MORN5 Gene

Disorders for MORN5 Gene

Relevant External Links for MORN5

Genetic Association Database (GAD)
MORN5
Human Genome Epidemiology (HuGE) Navigator
MORN5
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MORN5

No disorders were found for MORN5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MORN5 Gene

Publications for MORN5 Gene

  1. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PMID: 20583170) Letra A. … Vieira A.R. (Am. J. Med. Genet. A 2010) 3 46 64
  2. Genome-wide association study of smoking behaviours among Bangladeshi adults. (PMID: 24665060) Argos M. … Ahsan H. (J. Med. Genet. 2014) 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for MORN5 Gene

Sources for MORN5 Gene

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