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Aliases for MORN4 Gene

Aliases for MORN4 Gene

  • MORN Repeat Containing 4 2 3 5
  • 44050 Protein 2 3
  • Protein 44050 3 4
  • C10orf83 3 4
  • Chromosome 10 Open Reading Frame 83 2
  • Retinophilin Homolog (Drosophila) 2
  • Retinophilin Homolog 3
  • Retinophilin 3
  • BA548K23.4 3
  • Rtp 3

External Ids for MORN4 Gene

Previous HGNC Symbols for MORN4 Gene

  • C10orf83

Previous GeneCards Identifiers for MORN4 Gene

  • GC10M099365
  • GC10M093000

Summaries for MORN4 Gene

GeneCards Summary for MORN4 Gene

MORN4 (MORN Repeat Containing 4) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MORN4 Gene

Genomics for MORN4 Gene

Regulatory Elements for MORN4 Gene

Promoters for MORN4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MORN4 on UCSC Golden Path with GeneCards custom track

Genomic Location for MORN4 Gene

Chromosome:
10
Start:
97,614,553 bp from pter
End:
97,634,156 bp from pter
Size:
19,604 bases
Orientation:
Minus strand

Genomic View for MORN4 Gene

Genes around MORN4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MORN4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MORN4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MORN4 Gene

Proteins for MORN4 Gene

  • Protein details for MORN4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NDC4-MORN4_HUMAN
    Recommended name:
    MORN repeat-containing protein 4
    Protein Accession:
    Q8NDC4
    Secondary Accessions:
    • Q86Y54

    Protein attributes for MORN4 Gene

    Size:
    146 amino acids
    Molecular mass:
    16236 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MORN4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MORN4 Gene

Proteomics data for MORN4 Gene at MOPED

Post-translational modifications for MORN4 Gene

No Post-translational modifications

Other Protein References for MORN4 Gene

No data available for DME Specific Peptides for MORN4 Gene

Domains & Families for MORN4 Gene

Protein Domains for MORN4 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MORN4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NDC4

UniProtKB/Swiss-Prot:

MORN4_HUMAN :
  • Contains 4 MORN repeats.
Similarity:
  • Contains 4 MORN repeats.
genes like me logo Genes that share domains with MORN4: view

No data available for Gene Families for MORN4 Gene

Function for MORN4 Gene

Phenotypes for MORN4 Gene

genes like me logo Genes that share phenotypes with MORN4: view

Animal Model Products

CRISPR Products

miRNA for MORN4 Gene

miRTarBase miRNAs that target MORN4

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MORN4 Gene

Localization for MORN4 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MORN4 Gene COMPARTMENTS Subcellular localization image for MORN4 gene
Compartment Confidence
cytosol 3
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MORN4 Gene

Pathways & Interactions for MORN4 Gene

SuperPathways for MORN4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MORN4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MORN4 Gene

Drugs & Compounds for MORN4 Gene

No Compound Related Data Available

Transcripts for MORN4 Gene

Unigene Clusters for MORN4 Gene

MORN repeat containing 4:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MORN4 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: - - -
SP2: -
SP3: - - -
SP4:

Relevant External Links for MORN4 Gene

GeneLoc Exon Structure for
MORN4
ECgene alternative splicing isoforms for
MORN4

Expression for MORN4 Gene

mRNA expression in normal human tissues for MORN4 Gene

SOURCE GeneReport for Unigene cluster for MORN4 Gene Hs.217409

genes like me logo Genes that share expression patterns with MORN4: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MORN4 Gene

Orthologs for MORN4 Gene

This gene was present in the common ancestor of animals.

Orthologs for MORN4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MORN4 36
  • 62 (a)
OneToOne
MORN4 35
  • 99.54 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia MORN4 35
  • 92.69 (n)
  • 96.58 (a)
MORN4 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MORN4 36
  • 68 (a)
OneToOne
MORN4 35
  • 94.52 (n)
  • 98.63 (a)
mouse
(Mus musculus)
Mammalia Morn4 16
Morn4 36
  • 98 (a)
OneToOne
Morn4 35
  • 91.78 (n)
  • 97.95 (a)
oppossum
(Monodelphis domestica)
Mammalia MORN4 36
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MORN4 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Morn4 35
  • 91.78 (n)
  • 97.95 (a)
chicken
(Gallus gallus)
Aves MORN4 35
  • 78.54 (n)
  • 85.62 (a)
MORN4 36
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MORN4 36
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia morn4 35
  • 71 (n)
  • 76.03 (a)
Str.13968 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6686 35
zebrafish
(Danio rerio)
Actinopterygii morn4 35
  • 69.41 (n)
  • 76.03 (a)
morn4 36
  • 74 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003547 35
  • 52.72 (n)
  • 48.94 (a)
fruit fly
(Drosophila melanogaster)
Insecta rtp 35
  • 52.58 (n)
  • 49.3 (a)
rtp 36
  • 35 (a)
OneToOne
Species with no ortholog for MORN4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MORN4 Gene

ENSEMBL:
Gene Tree for MORN4 (if available)
TreeFam:
Gene Tree for MORN4 (if available)

Paralogs for MORN4 Gene

(13) SIMAP similar genes for MORN4 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with MORN4: view

No data available for Paralogs for MORN4 Gene

Variants for MORN4 Gene

Sequence variations from dbSNP and Humsavar for MORN4 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1009575 -- 97,614,630(-) AGCCG(C/T)GTGCC utr-variant-3-prime
rs2050321 -- 97,635,193(-) ctttt(A/G)tggtg upstream-variant-2KB
rs2065669 -- 97,615,712(-) ggagt(A/C/G/T)tcgct utr-variant-3-prime
rs3814556 -- 97,616,395(+) CCATC(A/G)GGGAA reference, synonymous-codon
rs3829907 -- 97,616,918(+) GCTCC(A/G)CCTAC intron-variant

Variation tolerance for MORN4 Gene

Residual Variation Intolerance Score: 54.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 27.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MORN4 Gene

HapMap Linkage Disequilibrium report
MORN4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MORN4 Gene

Disorders for MORN4 Gene

Relevant External Links for MORN4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MORN4

No disorders were found for MORN4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MORN4 Gene

Publications for MORN4 Gene

  1. Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins. (PMID: 25822849) Mecklenburg K.L. … O'Tousa J.E. (PLoS ONE 2015) 2 3 67
  2. A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. (PMID: 22496551) Bhattacharya M.R. … DiAntonio A. (J. Neurosci. 2012) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Drosophila retinophilin contains MORN repeats and is conserved in humans. (PMID: 17285308) Mecklenburg K.L. (Mol. Genet. Genomics 2007) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for MORN4 Gene

Sources for MORN4 Gene

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