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Aliases for MORN2 Gene

Aliases for MORN2 Gene

  • MORN Repeat Containing 2 2 3 5
  • MORN Motif Protein In Testis 3 4
  • MOPT 3 4
  • Protein Containing Single MORN Motif In Testis 3
  • MORN Repeat-Containing Protein 2 3
  • BLOCK27 3

External Ids for MORN2 Gene

Previous GeneCards Identifiers for MORN2 Gene

  • GC02P039015
  • GC02P038956
  • GC02P039103
  • GC02P038841

Summaries for MORN2 Gene

GeneCards Summary for MORN2 Gene

MORN2 (MORN Repeat Containing 2) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MORN2 Gene

  • Might have a role in spermatogenesis.

Additional gene information for MORN2 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MORN2 Gene

Genomics for MORN2 Gene

GeneHancer (GH) Regulatory Elements for MORN2 Gene

Promoters and enhancers for MORN2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I038874 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.1 -96 1.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 POLR2B ZNF766 E2F8 DHX57 MORN2 ENSG00000225284
GH02I038540 Enhancer 1.5 FANTOM5 Ensembl ENCODE 9.6 -333.5 -333522 3.4 PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B FEZF1 DMAP1 CBX5 E2F8 SRSF7 SOS1 DHX57 ENSG00000235586 HNRNPLL ENSG00000232518 GALM MAP4K3 ENSG00000252473 CYP1B1
GH02I039215 Enhancer 1.3 FANTOM5 Ensembl ENCODE 9.7 +341.3 341307 2.8 HDAC1 FOXA2 ARNT RARA SIRT6 RUNX3 CREM ZC3H11A ZNF518A ZNF781 SOS1 SRSF7 THUMPD2 ARHGEF33 ENSG00000202309 ENSG00000252473 DHX57 MORN2 CDKL4 GC02M039185
GH02I038946 Enhancer 1.1 Ensembl ENCODE 10.9 +71.5 71497 1.1 ELF3 FOXA2 RB1 ARID4B SIN3A DNMT3B ZNF48 RAD21 RARA RFX5 SRSF7 MORN2 DHX57 ENSG00000225284 LOC105374471 RN7SL96P ARHGEF33
GH02I038959 Promoter/Enhancer 1 Ensembl ENCODE 10.9 +84.6 84569 1.3 RING1 POLR2A MAX EZH2 LOC375196 DHX57 ASS1P2 MORN2 THUMPD2 SRSF7 SOS1 SOS1-IT1 ARHGEF33
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MORN2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MORN2 gene promoter:

Genomic Locations for MORN2 Gene

Genomic Locations for MORN2 Gene
53,111 bases
Plus strand

Genomic View for MORN2 Gene

Genes around MORN2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MORN2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MORN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MORN2 Gene

Proteins for MORN2 Gene

  • Protein details for MORN2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    MORN repeat-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • Q6UL00

    Protein attributes for MORN2 Gene

    79 amino acids
    Molecular mass:
    8939 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MORN2 Gene

Post-translational modifications for MORN2 Gene

No Post-translational modifications

Other Protein References for MORN2 Gene

No data available for DME Specific Peptides for MORN2 Gene

Domains & Families for MORN2 Gene

Gene Families for MORN2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MORN2 Gene


Suggested Antigen Peptide Sequences for MORN2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MORN2: view

No data available for UniProtKB/Swiss-Prot for MORN2 Gene

Function for MORN2 Gene

Molecular function for MORN2 Gene

UniProtKB/Swiss-Prot Function:
Might have a role in spermatogenesis.

Phenotypes From GWAS Catalog for MORN2 Gene

Gene Ontology (GO) - Molecular Function for MORN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with MORN2: view

Phenotypes for MORN2 Gene

GenomeRNAi human phenotypes for MORN2:
genes like me logo Genes that share phenotypes with MORN2: view

Animal Model Products

miRNA for MORN2 Gene

miRTarBase miRNAs that target MORN2

Clone Products

  • Addgene plasmids for MORN2

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MORN2 Gene

Localization for MORN2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MORN2 Gene

Cytoplasmic vesicle, secretory vesicle, acrosome. Nucleus. Note=Associated with the acrosome during post-meiotic stages of spermatogenesis. Appears to migrate to the nucleus during the final step of spermiogenesis. {ECO:0000250 UniProtKB:Q6UL01}.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MORN2 gene
Compartment Confidence
nucleus 4
cytosol 3
extracellular 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for MORN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001669 acrosomal vesicle IEA --
GO:0005634 nucleus IEA --
GO:0031410 cytoplasmic vesicle IEA --
genes like me logo Genes that share ontologies with MORN2: view

Pathways & Interactions for MORN2 Gene

SuperPathways for MORN2 Gene

No Data Available

Interacting Proteins for MORN2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q502X0-MORN2_HUMAN ENSP00000344551 for MORN2 Gene via IID UniProtKB STRING

Gene Ontology (GO) - Biological Process for MORN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with MORN2: view

No data available for Pathways by source and SIGNOR curated interactions for MORN2 Gene

Drugs & Compounds for MORN2 Gene

No Compound Related Data Available

Transcripts for MORN2 Gene

mRNA/cDNA for MORN2 Gene

(2) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MORN2 Gene

MORN repeat containing 2:
Representative Sequences:

Clone Products

  • Addgene plasmids for MORN2

Alternative Splicing Database (ASD) splice patterns (SP) for MORN2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5
SP1: -

Relevant External Links for MORN2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MORN2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MORN2 Gene

mRNA differential expression in normal tissues according to GTEx for MORN2 Gene

This gene is overexpressed in Testis (x6.5).

NURSA nuclear receptor signaling pathways regulating expression of MORN2 Gene:


SOURCE GeneReport for Unigene cluster for MORN2 Gene:

genes like me logo Genes that share expression patterns with MORN2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MORN2 Gene

Orthologs for MORN2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MORN2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MORN2 33 34
  • 99.58 (n)
(Bos Taurus)
Mammalia MORN2 33 34
  • 92.83 (n)
(Canis familiaris)
Mammalia MORN2 33 34
  • 92.83 (n)
(Rattus norvegicus)
Mammalia Morn2 33
  • 87.34 (n)
(Mus musculus)
Mammalia Morn2 33 16 34
  • 86.92 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 68 (a)
-- 34
  • 58 (a)
(Monodelphis domestica)
Mammalia MORN2 34
  • 42 (a)
(Gallus gallus)
Aves MORN2 33
  • 67.51 (n)
(Anolis carolinensis)
Reptilia MORN2 34
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia morn2 33
  • 71.73 (n)
(Danio rerio)
Actinopterygii morn2 33 34
  • 60.76 (n)
Species where no ortholog for MORN2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MORN2 Gene

Gene Tree for MORN2 (if available)
Gene Tree for MORN2 (if available)

Paralogs for MORN2 Gene

(12) SIMAP similar genes for MORN2 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with MORN2: view

No data available for Paralogs for MORN2 Gene

Variants for MORN2 Gene

Sequence variations from dbSNP and Humsavar for MORN2 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000149694 -- 38,880,036(+) G/T intron_variant
rs1000520205 -- 38,878,372(+) T/C intron_variant
rs1000568303 -- 38,882,240(+) G/T intron_variant
rs1000987807 -- 38,874,064(+) A/T upstream_transcript_variant
rs1001005568 -- 38,880,200(+) G/A 5_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for MORN2 Gene

Variant ID Type Subtype PubMed ID
nsv2692 CNV deletion 18451855

Variation tolerance for MORN2 Gene

Gene Damage Index Score: 4.74; 66.42% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MORN2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MORN2 Gene

Disorders for MORN2 Gene

Additional Disease Information for MORN2

No disorders were found for MORN2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MORN2 Gene

Publications for MORN2 Gene

  1. Identification and characterization of a novel mouse and human MOPT gene containing MORN-motif protein in testis. (PMID: 19913896) Choi YJ … Kim JH (Theriogenology 2010) 3 4 58
  2. Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. (PMID: 19451621) Landers JE … Brown RH (Proceedings of the National Academy of Sciences of the United States of America 2009) 3 44 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for MORN2 Gene

  • Addgene plasmids for MORN2

Sources for MORN2 Gene

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