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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MORF4L2 Gene

protein-coding   GIFtS: 53
GCID: GC0XM102930

mortality factor 4 like 2

 Explore 6 diseases affiliated with
MORF4L2 via our new
 Human Malady Compendium 
Biological research products
for MORF4L2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Mortality Factor 4 Like 21 2     MORF-Related Gene X Protein2 3
MRGX1 2 3 5     MORFL22 5
KIAA00261 3 5     Mortality Factor 4-Like Protein 22
Protein MSL3-22 3     MSL3-2 Protein2
Transcription Factor-Like Protein MRGX2 3     

External Ids:    HGNC: 168491   Entrez Gene: 96432   Ensembl: ENSG000001235627   OMIM: 3004095   UniProtKB: Q150143   

Export aliases for MORF4L2 gene to outside databases

Previous GC identifers: GC0XM099839 GC0XM100963 GC0XM101702 GC0XM102736 GC0XM102817 GC0XM092587


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MO4L2_HUMAN, Q15014
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of
select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome
- DNA interactions and promote interaction of the modified histones with other proteins which positively regulate
transcription. This complex may be required for the activation of transcriptional programs associated with oncogene
and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence,
apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed
by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly
recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by
deacetylation of nucleosomal histones

Gene Wiki entry for MORF4L2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MORF4L2 gene promoter:
         NF-1   CBF-B   CBF-A   SRF (504 AA)   CBF(2)   CBF-C   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MORF4L2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MORF4L2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MORF4L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22   Ensembl cytogenetic band:  Xq22.2   HGNC cytogenetic band: Xq22

MORF4L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MORF4L2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM102930:  view genomic region     (about GC identifiers)

Start:
102,930,424 bp from pter      End:
102,943,086 bp from pter
Size:
12,663 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MO4L2_HUMAN, Q15014 (See protein sequence)
Recommended Name: Mortality factor 4-like protein 2  
Size: 288 amino acids; 32308 Da
Subunit: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and
the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A,
MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus
E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60
catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase
complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1.
May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of
transcriptional repressors
Subcellular location: Nucleus
Secondary accessions: B3KP92 D3DXA5 Q567V0 Q8J026

Explore the universe of human proteins at neXtProt for MORF4L2: NX_Q15014

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15014

  • MORF4L2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (16 alternative transcripts): 
    NP_001135890.1  NP_001135891.1  NP_001135892.1  NP_001135893.1  NP_001135894.1  NP_001135895.1  NP_001135896.1  NP_001135897.1  
    NP_001135898.1  NP_001135899.1  NP_001135900.1  NP_001135901.1  NP_001135902.1  NP_001135903.1  NP_001135904.1  NP_036418.1  

    ENSEMBL proteins: 
     ENSP00000353643   ENSP00000361703   ENSP00000391969   ENSP00000413664   ENSP00000393283  
     ENSP00000400938   ENSP00000408607   ENSP00000415476   ENSP00000394417   ENSP00000410532  
     ENSP00000416120  

    Human Recombinant Protein Products: 
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    Novus Biologicals MORF4L2 Proteins
    Novus Biologicals MORF4L2 Lysate
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    ProSpec Recombinant Protein for MORF4L2
    Uscn Proteins for MORF4L2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus IDA10942595


    MORF4L2 for ontologies           About GeneDecksing



    MORF4L2 Antibody Products: 
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    Uscn Antibodies for MORF4L2
    ThermoFisher Antibodies for MORF4L2

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    Uscn ELISAs and CLIAs for MORF4L2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MORF4L2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR008676 MRG
     IPR026541 MRG_dom

    Graphical View of Domain Structure for InterPro Entry Q15014

    ProtoNet protein and cluster: Q15014

    1 Blocks protein family: IPB008676 MRG

    UniProtKB/Swiss-Prot: MO4L2_HUMAN, Q15014
    Similarity: Contains 1 MRG domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MO4L2_HUMAN, Q15014
    Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of
    select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome
    - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate
    transcription. This complex may be required for the activation of transcriptional programs associated with oncogene
    and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence,
    apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed
    by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly
    recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by
    deacetylation of nucleosomal histones

    miRNA
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    8/55 QIAGEN miScript miRNA Assays for microRNAs that regulate MORF4L2 (see all 55):
    hsa-miR-4317 hsa-miR-3678-3p hsa-miR-323-3p hsa-miR-29a hsa-miR-105 hsa-miR-1276 hsa-miR-3658 hsa-miR-629
    SwitchGear 3'UTR luciferase reporter plasmidMORF4L2 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORF4L2

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11988016


    MORF4L2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MORF4L2:
     Synthetic lethal with c-Myc af 

    Animal Models:
         Mouse knock-out Morf4l2tm1.1Kto for MORF4L2
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Morf4l2):
     embryogenesis  growth/size  mortality/aging  normal 

    MORF4L2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MORF4L2

    5/602 Interacting proteins for MORF4L2 (Q150141, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 602)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MORF4L1Q9UBU82, 3MINT-7945693 MINT-8076071 I2D: score=1 
    RUVBL1Q9Y2652, 3MINT-7945693 MINT-8076071 I2D: score=1 
    RUVBL2Q9Y2302, 3MINT-7945693 MINT-8076071 I2D: score=1 
    HDAC1Q135472, 3MINT-7945693 I2D: score=4 
    ACTL6AO960192, 3MINT-7945693 I2D: score=3 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001558regulation of cell growth NAS--
    GO:0006281DNA repair IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0016568chromatin modification IEA--


    MORF4L2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MORF4L2
    Search CenterWatch for drugs/clinical trials and news about MORF4L2 / MO4L2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MORF4L2 gene (16 alternative transcripts): 
    NM_001142418.1  NM_001142419.1  NM_001142420.1  NM_001142421.1  NM_001142422.1  NM_001142423.1  NM_001142424.1  NM_001142425.1  
    NM_001142426.1  NM_001142427.1  NM_001142428.1  NM_001142429.1  NM_001142430.1  NM_001142431.1  NM_001142432.1  NM_012286.2  

    Unigene Clusters for MORF4L2:

    Mortality factor 4 like 2
    Hs.326387  [show with all ESTs], Hs.597035  [show with all ESTs]
    Unigene Representative Sequences: BC035249, BU189645
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360458 ENST00000372620 ENST00000441076 ENST00000434230 ENST00000418819
    ENST00000442614 ENST00000492116 ENST00000422355 ENST00000474653 ENST00000467755
    ENST00000498064 ENST00000488331 ENST00000433176(uc004elc.3 uc004ele.3 uc004elf.3 uc011msa.2 uc011msb.2 uc011msc.2 uc011msd.2 uc004eld.3)
    ENST00000422154(uc004elb.3 uc004ekx.3 uc004eky.3 uc010nos.3 uc004ekz.3 uc011mry.2 uc011mrz.2)
    ENST00000451301(uc004ela.3) ENST00000423833(uc004ekw.3)

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    8/55 QIAGEN miScript miRNA Assays for microRNAs that regulate MORF4L2 (see all 55):
    hsa-miR-4317 hsa-miR-3678-3p hsa-miR-323-3p hsa-miR-29a hsa-miR-105 hsa-miR-1276 hsa-miR-3658 hsa-miR-629
    SwitchGear 3'UTR luciferase reporter plasmidMORF4L2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: AB050779.1 

    24/49 DOTS entries (see all 49):

    DT.87017524  DT.100888283  DT.100888281  DT.91831219  DT.101985584  DT.97794474  DT.92463009  DT.100888287 
    DT.100888302  DT.102837771  DT.92463014  DT.95105395  DT.121281302  DT.100888303  DT.100888289  DT.97855549 
    DT.95079818  DT.40116312  DT.95338171  DT.95105332  DT.40209820  DT.92463016  DT.121281189  DT.121281242 

    24/1092 AceView cDNA sequences (see all 1092):

    AA580303 CA868263 CA952438 BU619597 BQ636354 CF141661 BG032050 AI610630 
    AA363189 BX509541 CR599214 AV704600 AA878284 AA206628 AI202482 CR599829 
    AA309095 BQ889460 BM469132 BQ420320 BQ878235 BU508252 BU950421 CR623631 

    GeneLoc Exon Structure

    5/24 Alternative Splicing Database (ASD) splice patterns (SP) for MORF4L2 (see all 24)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4a · 4b · 4c · 4d · 4e ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b ·
    SP1:                          -     -     -     -     -     -     -     -     -     -     -           -     -                                                   
    SP2:                          -     -     -     -     -     -     -     -     -     -     -           -     -           -     -                                 
    SP3:                                                                          -     -     -           -     -           -     -                                 
    SP4:                                                                          -     -     -           -     -                                                   
    SP5:                                                                          -     -     -           -     -           -                                       

    ExUns: 7c · 7d · 7e · 7f · 7g · 7h · 7i · 7j · 7k · 7l · 7m · 7n · 7o · 7p
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for MORF4L2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MORF4L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATAGAGGCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MORF4L2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MORF4L2

    SOURCE GeneReport for Unigene clusters: Hs.326387 Hs.597035
        SABiosciences Custom PCR Arrays for MORF4L2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORF4L2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MORF4L2 gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves MORF4L16
    mortality factor 4 like 1 isoform 1
    57(a)
    1 → many
    10(21826523-21842564)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    70(a)
    69(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    GL343835.1(85398-90372)
    GL343392.1(127921-131583)
    zebrafish
    (Danio rerio)
    Actinopterygii morf4l16
    mortality factor 4 like 1
    62(a)
    1 → many
    18(19814734-19826018)
    fruit fly
    (Drosophila melanogaster)
    Insecta MRG156
    MRG15
    24(a)
    1 → many
    3R(11102162-11103831)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G372806
    AT1G027406
    mortality factor 4-like protein 1
    22(a)
    19(a)
    many ↔ many
    many ↔ many
    4(17546584-17549424)
    1(599416-602038)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 3)
    chromatin modification-related protein EAF3, putat...
    chromatin modification-related protein EAF3, putat...
    (see all 3)
    24(a)
    18(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    11(19631877-19640628)
    4(88024-96924)


    ENSEMBL Gene Tree for MORF4L2 (if available)
    TreeFam Gene Tree for MORF4L2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MORF4L2 gene
    MSL32  MORF4L12  
    1 SIMAP similar gene for MORF4L2 using alignment to 6 protein entries:     MO4L2_HUMAN (see all proteins):
    MORF4L1

    MORF4L2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MORF4L2
    PGOHUM00000245911


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/187 NCBI SNPs in MORF4L2 are shown (see all 187    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs173425881,2
    C,F,H,--102930301(+) TACATC/GATTCT 16 -- int113Minor allele frequency- N:0.00NA EA NS WA 1054
    rs1847334431,2
    --102930309(+) TCTTAC/TTTGCA 16 -- int10--------
    rs31791291,2
    C--102930429(-) TCAAAG/ACAAGT 16 -- ut311Minor allele frequency- A:0.00NA 2
    rs10645531,2
    C--102930667(-) TATGGT/GGCTTG 16 -- ut312Minor allele frequency- G:0.41MN NA 186
    rs589982501,2
    C--102930672(+) ACCAT-/AAAAAA 16 -- ut311Minor allele frequency- A:0.00CSA 2
    rs8741,2
    C,F,H,--102930960(-) TGTTTT/CCCGTT 16 -- ut31 ese317Minor allele frequency- C:0.31MN NS EA NA 2328
    rs1891546781,2
    --102931006(+) TTAAAA/GAACAT 16 -- ut310--------
    rs1480094141,2
    F--102931304(+) CATTGG/CAGCAT 32 /P /A mis11Minor allele frequency- C:0.00NA 4550
    rs2012178371,2
    --102931563(+) AGCCAC/TGGTTT 32 P syn10--------
    rs1424853741,2
    C,F,--102931606(+) TTCTAT/CTCTTA 32 /N /S mis11Minor allele frequency- C:0.00NA 4320

    HapMap Linkage Disequilibrium report for MORF4L2 (102930424 - 102943086 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MORF4L2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MORF4L2 for disorders           About GeneDecksing

    OMIM gene information: 300409    OMIM disorders: --

    6 diseases for MORF4L2:    About MalaCards
    cervix uteri carcinoma in situ    paraneoplastic cerebellar degeneration    cerebellar degeneration    eaf
    neuronitis    carcinoma

    1 disease from the University of Copenhagen DISEASES database for MORF4L2:
    Cervix uteri carcinoma in situ

    Export disorders for MORF4L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MORF4L2 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with MORF4L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. (PubMed id 9891081)1, 2, 3 Bertram M.J.... Pereira-Smith O.M. (1999)
    2. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2, 3 Nomura N.... Tabata S. (1994)
    3. MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. (PubMed id 14506250)1, 2, 9 Tominaga K....Pereira-Smith O.M. (2003)
    4. Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and transducin-like enhancer of Split. (PubMed id 12391155)1, 2, 9 Yochum G.S. and Ayer D.E. (2002)
    5. Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. (PubMed id 12963728)1, 2, 9 Cai Y.... Conaway J.W. (2003)
    6. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    10. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9643 HGNC: 16849 AceView: MORF4L2 Ensembl:ENSG00000123562 euGenes: HUgn9643
    ECgene: MORF4L2 H-InvDB: MORF4L2

    (According to HUGE)
    About This Section
    HUGE: KIAA0026

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MORF4L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MORF4L2 gene:
    Search GeneIP for patents involving MORF4L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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