MORF4L1 Gene
protein-coding GIFtS: 53
GCID: GC15P079102
|
|
mortality factor 4 like 1
| |
Aliases
for MORF4L1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mortality Factor 4 Like 11 2 | | Transcription Factor-Like Protein MRG152 3 | | MRG151 2 3 5 | | MORF-Related Gene 15 Protein2 3 | | Eaf31 2 | | S863-62 | | HsT177251 2 | | Esa1p-Associated Factor 3 Homolog2 | | MEAF31 2 | | MORF-Related Gene On Chromosome 152 | | MORFRG151 2 | | Mortality Factor 4-Like Protein 12 | | Protein MSL3-12 3 | | |
Export aliases for MORF4L1 gene to outside databasesPrevious GC identifers: GC15P072322 GC15P076678 GC15P076881 GC15P076952 GC15P079132 |
Summaries
for MORF4L1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MO4L1_HUMAN, Q9UBU8Function: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activationof select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alternucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positivelyregulate transcription. This complex may be required for the activation of transcriptional programs associated withoncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicativesenescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part,contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair whendirectly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription bydeacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycinC (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci
Gene Wiki entry for MORF4L1
|
Genomic Views
for MORF4L1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MORF4L1 gene promoter:
Spz1 p53 Ik-3 FOXC1 POU2F1 POU2F1a Zic1 ARP-1 ATF Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for MORF4L1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MORF4L1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q24 Ensembl cytogenetic band: 15q25.1 HGNC cytogenetic band: 15q25.1MORF4L1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P079102: view genomic region
(about GC identifiers)
Start:
|
79,102,829 bp from pter |
End:
|
79,190,475 bp from pter |
Size:
|
87,647 bases |
Orientation:
|
plus strand |
|
Proteins
for MORF4L1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MO4L1_HUMAN, Q9UBU8 (See
protein sequence)Recommended Name: Mortality factor 4-like protein 1 Size: 362 amino acids; 41474 Da
Subunit: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 andthe subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A,MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. The NuA4 complex interacts with MYC and theadenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack theKAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the mSin3A histonedeacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with RB1and KAT8. May also interact with PHF12 and one or more as yet undefined members of the TLE (transducin-like enhancerof split) family of transcriptional repressors. Interacts with the N-terminus of MRFAP1. Found in a complex composedof MORF4L1, MRFAP1 and RB1. Interacts with the entire BRCA complex, which contains BRCA1, PALB2, BRCA2 and RAD51.Interacts with PALB2. Forms a complex with MSL1 and NUPR1
Subcellular location: Nucleus
Sequence caution: Sequence=AAG17253.1; Type=Frameshift; Positions=348, 360;
5 PDB 3D structures from  and Proteopedia  for MORF4L1:2AQL (3D)
2EFI (3D)
2F5J (3D)
2F5K (3D)
2LKM (3D)
Secondary accessions: B4DKN6 B7Z6R1 D3DW88 O95899 Q5QTS1 Q6NVX8 Q86YT7 Q9HBP6 Q9NSW5Alternative splicing: 3 isoforms: Q9UBU8-1 Q9UBU8-2 Q9UBU8-3 Explore the universe of human proteins at neXtProt for MORF4L1: NX_Q9UBU8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UBU8
MORF4L1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001252532.1 NP_001252533.1 NP_001252534.1 NP_006782.1 NP_996670.1
ENSEMBL proteins: ENSP00000368850 ENSP00000408880 ENSP00000331310 ENSP00000454191 ENSP00000453231 ENSP00000453738 ENSP00000452717 ENSP00000452808 ENSP00000453351 ENSP00000453432 ENSP00000453625 ENSP00000454030 ENSP00000453972
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MORF4L1 for ontologies About GeneDecksing
MORF4L1 Antibody Products:
Assay Products for MORF4L1: |
Protein
Domains /
Families
for MORF4L1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MORF4L1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UBU8ProtoNet protein and cluster: Q9UBU8 2 Blocks protein families: IPB000953 Chromo domain IPB008676 MRG
UniProtKB/Swiss-Prot: MO4L1_HUMAN, Q9UBU8Similarity: Contains 1 MRG domain |
Function
for MORF4L1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MO4L1_HUMAN, Q9UBU8Function: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activationof select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alternucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positivelyregulate transcription. This complex may be required for the activation of transcriptional programs associated withoncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicativesenescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part,contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair whendirectly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription bydeacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycinC (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): MORF4L1 (NM_006791) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MORF4L1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MORF4L1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORF4L1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
MORF4L1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MORF4L1:
Animal Models:
Mouse knock-out Morf4l1tm1Kto for MORF4L1
11 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Morf4l1):
MORF4L1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MORF4L1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for MORF4L1
MORF4L1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MORF4L1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/741 Interacting proteins for MORF4L1 (Q9UBU82, 3 ENSP000003313104) via UniProtKB, MINT, STRING, and/or I2D (see all 741)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000724 | double-strand break repair via homologous recombination |
IDA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0016575 | histone deacetylation |
IDA | 14966270 | | GO:0040008 | regulation of growth |
IEA | -- |
MORF4L1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MORF4L1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MORF4L1 for compounds About GeneDecksing
 Browse Tocris compounds for MORF4L1
1 Novoseek chemical compound relationship for MORF4L1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leucine |
26.1 |
4 |
11500496 (2), 12397079 (1) |
Search CenterWatch for drugs/clinical trials and news about MORF4L1 / MO4L1
|
Transcripts
for MORF4L1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MORF4L1 gene (5 alternative transcripts): NM_001265603.1 NM_001265604.1 NM_001265605.1 NM_006791.3 NM_206839.2 Unigene Cluster for MORF4L1: Mortality factor 4 like 1 Hs.374503 [show with all ESTs]Unigene Representative Sequence: NM_20683918/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000379535 ENST00000559697 ENST00000426013(uc002bem.3 uc010une.2)
ENST00000331268(uc002bel.3) ENST00000557961 ENST00000559930 ENST00000558746
ENST00000558893(uc010blj.1) ENST00000558830 ENST00000558522(uc010bli.1)
ENST00000559619 ENST00000559345 ENST00000561171 ENST00000558502 ENST00000559258
ENST00000559690 ENST00000559158 ENST00000560422
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MORF4L1 (NM_006791) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MORF4L1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MORF4L1 |
Additional cDNA sequence: AF070664.1 AF100615.1 AF109188.1 AF131847.1 AF161546.1 AF167173.1 AF218011.1 AK098485.1 AK296650.1 AK300789.1 AK310702.1 AL137697.1 AY148481.1 BC002936.2 BC022845.2 BC067826.1 BC121092.1 BC121093.1 BC141840.1 24/56 DOTS entries (see all 56): DT.100891602 DT.100722399 DT.100891590 DT.100891587 DT.100891561 DT.91784109 DT.100891566 DT.102838436 DT.95341884 DT.100891585 DT.121068697 DT.95164056 DT.100891599 DT.100891605 DT.95164037 DT.97809450 DT.100891606 DT.121336510 DT.100891578 DT.100891595 DT.121336540 DT.95294104 DT.100891584 DT.100891592 24/1004 AceView cDNA sequences (see all 1004): BM923800 BE513480 CB069604 BM263012 BQ654089 CB127836 AW408255 CK431121 BU179044 AW273394 CR625082 BQ423707 AI299238 CR606633 CB215353 BG027607 BE275562 BQ069274 AA809076 AA738286 BQ130442 BM550693 CR622863 BX378329
GeneLoc Exon Structure
|
Expression
for MORF4L1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MORF4L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAGACGCAA
About this image
See MORF4L1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MORF4L1
SOURCE GeneReport for Unigene cluster: Hs.374503
SABiosciences Custom PCR Arrays for MORF4L1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MORF4L1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MORF4L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MORF4L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MORF4L1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORF4L1 |
Orthologs
for MORF4L1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MORF4L1 gene from 9/29 species (see all 29) About this table
ENSEMBL Gene Tree for MORF4L1 (if available)
TreeFam Gene Tree for MORF4L1 (if available) |
Paralogs
for MORF4L1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MORF4L1 gene
- MSL32 MORF4L22
1 SIMAP similar gene for MORF4L1 using alignment to 12 protein entries: MO4L1_HUMAN (see all proteins):MORF4L2
MORF4L1 for paralogs About GeneDecksing
5/9 Pseudogenes.org Pseudogenes for MORF4L1 (see all 9)
PGOHUM00000242175 PGOHUM00000239350 PGOHUM00000248380 PGOHUM00000244349 PGOHUM00000245210
|
Genomic Variants
for MORF4L1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MORF4L1 (79102829 - 79190475 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MORF4L1
1 CNV: 7073 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MORF4L1 |
|
Disorders
/ Diseases
for MORF4L1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MORF4L1 for disorders About GeneDecksing
OMIM gene information: 607303
OMIM disorders: --
5  diseases for MORF4L1: About MalaCardseaf paraneoplastic cerebellar degeneration cerebellar degeneration retinoblastoma
breast cancer
2 Novoseek disease relationships for MORF4L1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| retinoblastoma |
46 |
3 |
11500496 (2), 17008723 (1) |
| tumors |
0 |
2 |
17008723 (1), 11500496 (1) |
Human Genome Epidemiology (HuGE) Navigator: MORF4L1 (2 documents)
Export disorders for MORF4L1 gene to outside databases
|
Publications
for MORF4L1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MORF4L1 gene, integrated from 9 sources (see all 63):
(articles sorted by number of sources associating them with MORF4L1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation. (PubMed id 12397079)1, 2, 9 Pardo P.S.... Pereira-Smith O.M. (2002)
- MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. (PubMed id 11500496)1, 2, 9 Leung J.K....Pereira-Smith O.M. (2001)
- Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and transducin-like enhancer of Split. (PubMed id 12391155)1, 2, 9 Yochum G.S. and Ayer D.E. (2002)
- The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14. (PubMed id 17008723)1, 2, 9 Zhang P.... Ding J. (2006)
- MRG15 binds directly to PALB2 and stimulates homology -directed repair of chromosomal breaks. (PubMed id 20332121)1, 2, 9 Hayakawa T....Andreassen P.R. (2010)
- Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain. (PubMed id 16407074)1, 2, 9 Bowman B.R.... Quiocho F.A. (2006)
- Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. (PubMed id 12963728)1, 2, 9 Cai Y.... Conaway J.W. (2003)
- The highly conserved and multifunctional NuA4 HAT complex. (PubMed id 15196461)1, 2 Doyon Y. and Cote J. (2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for MORF4L1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MORF4L1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MORF4L1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MORF4L1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MORF4L1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MORF4L1 gene:
Search GeneIP for patents involving MORF4L1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MORF4L1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MORF4L1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MORF4L1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MORF4L1 | | | OriGene Protein Over-expression Lysate for MORF4L1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MORF4L1 | | OriGene 3'-UTR Clone for MORF4L1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MORF4L1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MORF4L1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MORF4L1 | | OriGene Custom Protein Services for MORF4L1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MORF4L1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MORF4L1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MORF4L1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MORF4L1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MORF4L1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MORF4L1 |
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| | | | Search Tocris compounds for MORF4L1 |
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 | | | MORF4L1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MORF4L1 |
|  |  |  | | | | ThermoFisher Antibodies for MORF4L1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MORF4L1 |
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