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MON2 Gene

protein-coding   GIFtS: 51
GCID: GC12P062860

MON2 Homolog (S. Cerevisiae)

(Previous name: MON2 homolog (yeast))
Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MON2 Homolog (S. Cerevisiae)1 2
MON2 Homolog (Yeast)1
Protein MON2 Homolog2
KIAA10403
SF213
Protein SF213

External Ids:    HGNC: 291771   Entrez Gene: 230412   Ensembl: ENSG000000619877   UniProtKB: Q7Z3U73   

Export aliases for MON2 gene to outside databases

Previous GC identifers: GC12P061147 GC12P059911


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MON2 Gene:
MON2 (MON2 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with MON2 include leishmaniasis, and cutaneous leishmaniasis. GO annotations related to this gene include ARF guanyl-nucleotide exchange factor activity.

UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7
Function: May be required for traffic between late Golgi and early endosomes (By similarity)

Gene Wiki entry for MON2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MON2 gene promoter:
         p53   MAZR   p300   Arnt   AREB6   POU2F1   POU2F1a   STAT3   TGIF   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMON2 promoter sequence
   Search Chromatin IP Primers for MON2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MON2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.1   Ensembl cytogenetic band:  12q14.1   HGNC cytogenetic band: 12q14.1

MON2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MON2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P062860:  view genomic region     (about GC identifiers)

Start:
62,860,597 bp from pter      End:
62,991,363 bp from pter
Size:
130,767 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7 (See protein sequence)
Recommended Name: Protein MON2 homolog  
Size: 1718 amino acids; 190487 Da
Sequence caution: Sequence=BAA82992.3; Type=Erroneous initiation;
Secondary accessions: A5D8U7 A7E2Y0 Q86TA2 Q8N3I5 Q8NAI0 Q8NHE2 Q9UPW1
Alternative splicing: 4 isoforms:  Q7Z3U7-1   Q7Z3U7-2   Q7Z3U7-3   Q7Z3U7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MON2: NX_Q7Z3U7

Explore proteomics data for MON2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys281, Lys288
  • Modification sites at PhosphoSitePlus

  • See MON2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001265398.1  NP_001265399.1  NP_001265400.1  NP_001265401.1  NP_055841.2  

    ENSEMBL proteins: 
     ENSP00000377252   ENSP00000447407   ENSP00000446626   ENSP00000449215   ENSP00000377249  
     ENSP00000446635   ENSP00000450136   ENSP00000446802   ENSP00000377250   ENSP00000280379  

    MON2 Human Recombinant Protein Products:

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    OriGene Custom Protein Services for MON2
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for MON2

    MON2 Antibody Products:

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    Novus Biologicals MON2 Antibody
    Abcam antibodies for MON2
    Cloud-Clone Corp. Antibodies for MON2
    Search ThermoFisher Antibodies for MON2
    LSBio Antibodies in human, mouse, rat for MON2

    MON2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MON2
    Cloud-Clone Corp. CLIAs for MON2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011989 ARM-like
     IPR026829 Mon2
     IPR016024 ARM-type_fold
     IPR015403 DUF1981_Sec7_assoc

    Graphical View of Domain Structure for InterPro Entry Q7Z3U7

    ProtoNet protein and cluster: Q7Z3U7

    1 Blocks protein domain: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7
    Similarity: Belongs to the MON2 family


    MON2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MON2_HUMAN, Q7Z3U7
    Function: May be required for traffic between late Golgi and early endosomes (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005086ARF guanyl-nucleotide exchange factor activity IBA--
    GO:0005488binding ----
    GO:0005515protein binding IPI18418388
         
    MON2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MON2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MON2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MON2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MON2

    miRNA
    Products:
        
    miRTarBase miRNAs that target MON2:
    hsa-mir-1 (MIRT005278), hsa-mir-21-5p (MIRT030763)

    Block miRNA regulation of human, mouse, rat MON2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MON2 (see all 118):
    hsa-miR-124* hsa-miR-323-3p hsa-miR-199a-3p hsa-miR-374a hsa-miR-3074-3p hsa-miR-409-5p hsa-miR-4325 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidMON2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MON2
    Predesigned siRNA for gene silencing in human, mouse, rat MON2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MON2

    Clone
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    OriGene clones in human, mouse for MON2 (see all 7)
    OriGene ORF clones in mouse, rat for MON2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MON2 (NM_015026)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON2

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for MON2
    Browse ESI BIO Cell Lines and PureStem Progenitors for MON2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005802trans-Golgi network IBA--

    MON2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MON2
    Interactions:

        Search GeneGlobe Interaction Network for MON2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MON2 (Q7Z3U71, 2, 3 ENSP000003772524) via UniProtKB, MINT, STRING, and/or I2D (see all 147)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006895Golgi to endosome transport ISS--
    GO:0015031protein transport IEA--
    GO:0016192vesicle-mediated transport IBA--
    GO:0030036actin cytoskeleton organization IBA--
    GO:0043087regulation of GTPase activity IBA--

    MON2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MON2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MON2 gene (5 alternative transcripts): 
    NM_001278469.1  NM_001278470.1  NM_001278471.1  NM_001278472.1  NM_015026.2  

    Unigene Cluster for MON2:

    MON2 homolog (S. cerevisiae)
    Hs.389378  [show with all ESTs]
    Unigene Representative Sequence: NM_015026
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393632 ENST00000546600 ENST00000549378(uc001srd.1) ENST00000547095
    ENST00000552738 ENST00000393629 ENST00000552115 ENST00000549286 ENST00000551307
    ENST00000547287 ENST00000549539 ENST00000546751 ENST00000551397 ENST00000393630(uc001sre.3 uc009zqj.3 uc010ssl.2 uc010ssm.2 uc010ssn.2 uc001srf.3 uc001srg.3)
    ENST00000280379

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MON2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MON2 (see all 118):
    hsa-miR-124* hsa-miR-323-3p hsa-miR-199a-3p hsa-miR-374a hsa-miR-3074-3p hsa-miR-409-5p hsa-miR-4325 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidMON2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MON2
    Predesigned siRNA for gene silencing in human, mouse, rat MON2
    Clone
    Products:
         
    OriGene clones in human, mouse for MON2 (see all 7)
    OriGene ORF clones in mouse, rat for MON2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MON2 (NM_015026)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MON2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MON2
      QuantiTect SYBR Green Assays in human, mouse, rat MON2
      QuantiFast Probe-based Assays in human, mouse, rat MON2

    Additional mRNA sequence: 

    AB017814.1 AB028963.3 AK022671.1 AK092646.1 AK123842.1 AL833066.2 AL834320.1 BC136621.1 
    BC141817.1 BC142710.1 BC144309.1 BC144324.1 BC151241.1 BX537415.1 

    13 DOTS entries:

    DT.455450  DT.100877882  DT.102827076  DT.100000058  DT.100023787  DT.100023784  DT.100668041  DT.121108118 
    DT.451855  DT.40199707  DT.92017820  DT.101967858  DT.70102778 

    Selected AceView cDNA sequences (see all 196):

    BU581677 AL118962 AA480553 AL596488 AA258132 AX747651 BI438902 AI167922 
    AA420431 AK092646 AB028963 BQ953738 CR590768 AA808267 BF445643 AA504489 
    AA227378 BG035276 BM842765 AW473753 AA257953 CA313672 AW273428 AI539093 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MON2 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22a ·
    SP1:                    -           -                                                                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                    -     -     -     -     -                                                                                                               
    SP5:                                                                                                                                                            

    ExUns: 22b · 22c ^ 23a · 23b ^ 24a · 24b · 24c ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32a · 32b
    SP1:                                                                                                                                    
    SP2:                                            -                                                           -     -                     
    SP3:                                                                    -     -                             -     -                     
    SP4:                                                                                                                                    
    SP5:        -                                                                                                                           


    ECgene alternative splicing isoforms for MON2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MON2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAACACAGC
    MON2 Expression
    About this image

    MON2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MON2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.389378
        Custom PCR Arrays for MON2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MON2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MON2
    QuantiTect SYBR Green Assays in human, mouse, rat MON2
    QuantiFast Probe-based Assays in human, mouse, rat MON2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MON2 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mon21 , 5 MON2 homolog (yeast)1, 5 85.96(n)1
    94.8(a)1
      10 (72.15 cM)5
    670741  NM_001163024.11  NP_001156496.11 
     1229920615 
    chicken
    (Gallus gallus)
    Aves MON21 MON2 homolog (S. cerevisiae) 83.53(n)
    93.88(a)
      417818  NM_001199605.1  NP_001186534.1 
    lizard
    (Anolis carolinensis)
    Reptilia MON26
    MON2 homolog (S. cerevisiae)
    92(a)
    1 ↔ 1
    5(51082174-51134587)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ068287.12   -- 81.44(n)    BJ068287.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc16c072 Transcribed sequences 70.9(n)    57047103 
    fruit fly
    (Drosophila melanogaster)
    Insecta mon21 mon2 54.82(n)
    51.31(a)
      326157  NM_001038795.2  NP_001033884.2 
    worm
    (Caenorhabditis elegans)
    Secernentea mon-21 mon-2 48.28(n)
    35.82(a)
      178153  NM_001268693.1  NP_001255622.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MON2(YNL297C)4 Peripheral membrane protein with a role in endocytosis more   --   14(76583-71673) 855420  NP_014102.1 


    ENSEMBL Gene Tree for MON2 (if available)
    TreeFam Gene Tree for MON2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MON2 (see all 2425)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345919451,2
    C--59936118(+) GTTGATTT/-TAATA 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs105548531,2
    C--59969864(+) CATGG-/CA    
       T
    /TCA
    TTGGA
    2 -- int1 cds11CSA 2
    rs1443441961,2
    --62858616(+) AGAAGC/TATTGT 1 -- us2k10--------
    rs1833159371,2
    --62858642(+) TCCAAC/TTGCAT 1 -- us2k10--------
    rs1478230111,2
    --62858832(+) TGCCTA/GTAATC 1 -- us2k10--------
    rs1879543311,2
    --62858837(+) GTAATC/GCCAGC 1 -- us2k10--------
    rs1130394991,2
    C,F--62858856(+) AGGTCG/AAGGTG 1 -- us2k12Minor allele frequency- A:0.03CSA WA 120
    rs1162143901,2
    C,F--62858963(+) GCCTGC/TGGTGT 1 -- us2k11Minor allele frequency- T:0.18WA 118
    rs1413746091,2
    --62859027(+) CTGAGC/TTCAGT 1 -- us2k10--------
    rs1914645161,2
    --62859050(+) GCCTGA/GGCAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MON2 (62860597 - 62991363 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for MON2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658375CNV Deletion23128226
    esv2745966CNV Deletion23290073
    esv274602CNV Insertion20981092
    esv268651CNV Insertion20981092
    nsv739CNV Insertion18451855
    nsv740CNV Insertion18451855
    dgv1433n71CNV Loss21882294
    nsv821671CNV Loss15273396
    nsv469418CNV Loss19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for MON2:    
    About MalaCards
    leishmaniasis    cutaneous leishmaniasis    visceral leishmaniasis    hiv-1
    malaria

    2 diseases from the University of Copenhagen DISEASES database for MON2:
    Visceral leishmaniasis     Cutaneous leishmaniasis

    MON2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

    Export disorders for MON2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MON2 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with MON2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. (PubMed id 16301316)1, 2, 3 Gillingham A.K.... Munro S. (J. Biol. Chem. 2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R.... Ohara O. (DNA Res. 1999)
    4. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (PLoS Genet. 2013)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. (PubMed id 23956138)1 Foerster S....Ritter C.A. (Proteomics 2013)
    7. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PubMed id 22678362)1 Stehling O.... Lill R. (Science 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23041 HGNC: 29177 AceView: KIAA1040 Ensembl:ENSG00000061987 euGenes: HUgn23041
    ECgene: MON2 H-InvDB: MON2

    (According to HUGE)
    About This Section

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    HUGE: KIAA1040

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MON2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MON2 gene:
    Search GeneIP for patents involving MON2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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