Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MON2 Gene

protein-coding   GIFtS: 51
GCID: GC12P062860

MON2 Homolog (S. Cerevisiae)

(Previous name: MON2 homolog (yeast))
Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
MON2 Homolog (S. Cerevisiae)1 2
MON2 Homolog (Yeast)1
Protein MON2 Homolog2
KIAA10403
SF213
Protein SF213

External Ids:    HGNC: 291771   Entrez Gene: 230412   Ensembl: ENSG000000619877   UniProtKB: Q7Z3U73   

Export aliases for MON2 gene to outside databases

Previous GC identifers: GC12P061147 GC12P059911


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MON2 Gene: 
MON2 (MON2 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with MON2 include leishmaniasis, and cutaneous leishmaniasis. GO annotations related to this gene include ARF guanyl-nucleotide exchange factor activity.

UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7
Function: May be required for traffic between late Golgi and early endosomes (By similarity)

Gene Wiki entry for MON2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MON2 gene promoter:
         p53   MAZR   p300   Arnt   AREB6   POU2F1   POU2F1a   STAT3   TGIF   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMON2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MON2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MON2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.1   Ensembl cytogenetic band:  12q14.1   HGNC cytogenetic band: 12q14.1

MON2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MON2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P062860:  view genomic region     (about GC identifiers)

Start:
62,860,597 bp from pter      End:
62,991,363 bp from pter
Size:
130,767 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7 (See protein sequence)
Recommended Name: Protein MON2 homolog  
Size: 1718 amino acids; 190487 Da
Sequence caution: Sequence=BAA82992.3; Type=Erroneous initiation;
Secondary accessions: A5D8U7 A7E2Y0 Q86TA2 Q8N3I5 Q8NAI0 Q8NHE2 Q9UPW1
Alternative splicing: 4 isoforms:  Q7Z3U7-1   Q7Z3U7-2   Q7Z3U7-3   Q7Z3U7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MON2: NX_Q7Z3U7

Explore proteomics data for MON2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z3U7

  • MON2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MON2 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001265398.1  NP_001265399.1  NP_001265400.1  NP_001265401.1  NP_055841.2  

    ENSEMBL proteins: 
     ENSP00000377252   ENSP00000447407   ENSP00000446626   ENSP00000449215   ENSP00000377249  
     ENSP00000446635   ENSP00000450136   ENSP00000446802   ENSP00000377250   ENSP00000280379  

    Human Recombinant Protein Products for MON2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MON2
    GenScript Custom Purified and Recombinant Proteins Services for MON2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MON2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005802trans-Golgi network IBA--

    MON2 for ontologies           About GeneDecksing



    MON2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MON2
    GenScript Custom Superior Antibodies Services for MON2
    Novus Biologicals MON2 Antibody
    Abcam antibodies for MON2
    Cloud-Clone Corp. Antibodies for MON2 
    Search ThermoFisher Antibodies for MON2
    LSBio Antibodies in human, mouse, rat for MON2 

    Assay Products for MON2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MON2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MON2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MON2 
    Cloud-Clone Corp. CLIAs for MON2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR011989 ARM-like
     IPR026829 MON2
     IPR016024 ARM-type_fold
     IPR015403 DUF1981_SEC7_assoc

    Graphical View of Domain Structure for InterPro Entry Q7Z3U7

    ProtoNet protein and cluster: Q7Z3U7

    1 Blocks protein domain: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: MON2_HUMAN, Q7Z3U7
    Similarity: Belongs to the MON2 family


    MON2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MON2_HUMAN, Q7Z3U7
    Function: May be required for traffic between late Golgi and early endosomes (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005086ARF guanyl-nucleotide exchange factor activity IBA--
    GO:0005488binding ----
    GO:0005515protein binding IPI18418388
         
    MON2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MON2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MON2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MON2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MON2 

    miRNA
    Products:
        
    miRTarBase miRNAs that target MON2:
    hsa-mir-1 (MIRT005278)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MON2
    8/118 QIAGEN miScript miRNA Assays for microRNAs that regulate MON2 (see all 118):
    hsa-miR-124* hsa-miR-323-3p hsa-miR-199a-3p hsa-miR-374a hsa-miR-3074-3p hsa-miR-409-5p hsa-miR-4325 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidMON2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MON2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MON2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MON2
    Sirion Biotech Customized adenovirus for overexpression of MON2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MON2 (see all 7)
    OriGene ORF clones in mouse, rat for MON2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MON2 (NM_015026)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MON2
    Search LifeMap BioReagents cell lines for MON2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MON2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/85 Interacting proteins for MON2 (Q7Z3U72, 3 ENSP000003772524) via UniProtKB, MINT, STRING, and/or I2D (see all 85)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006895Golgi to endosome transport ISS--
    GO:0015031protein transport IEA--
    GO:0016192vesicle-mediated transport IBA--
    GO:0030036actin cytoskeleton organization IBA--

    MON2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MON2

    Search CenterWatch for drugs/clinical trials and news about MON2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MON2 gene (5 alternative transcripts): 
    NM_001278469.1  NM_001278470.1  NM_001278471.1  NM_001278472.1  NM_015026.2  

    Unigene Cluster for MON2:

    MON2 homolog (S. cerevisiae)
    Hs.389378  [show with all ESTs]
    Unigene Representative Sequence: NM_015026
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393632 ENST00000546600 ENST00000549378(uc001srd.1) ENST00000547095
    ENST00000552738 ENST00000393629 ENST00000552115 ENST00000549286 ENST00000551307
    ENST00000547287 ENST00000549539 ENST00000546751 ENST00000551397 ENST00000393630(uc001sre.3 uc009zqj.3 uc010ssl.2 uc010ssm.2 uc010ssn.2 uc001srf.3 uc001srg.3)
    ENST00000280379

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MON2
    8/118 QIAGEN miScript miRNA Assays for microRNAs that regulate MON2 (see all 118):
    hsa-miR-124* hsa-miR-323-3p hsa-miR-199a-3p hsa-miR-374a hsa-miR-3074-3p hsa-miR-409-5p hsa-miR-4325 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidMON2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MON2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MON2
    Clone
    Products:
         
    OriGene clones in human, mouse for MON2 (see all 7)
    OriGene ORF clones in mouse, rat for MON2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MON2 (NM_015026)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MON2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MON2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MON2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MON2

    Additional mRNA sequence: 

    AB017814.1 AB028963.3 AK022671.1 AK092646.1 AK123842.1 AL833066.2 AL834320.1 BC136621.1 
    BC141817.1 BC142710.1 BC144309.1 BC144324.1 BC151241.1 BX537415.1 

    13 DOTS entries:

    DT.455450  DT.100877882  DT.102827076  DT.100000058  DT.100023787  DT.100023784  DT.100668041  DT.121108118 
    DT.451855  DT.40199707  DT.92017820  DT.101967858  DT.70102778 

    24/196 AceView cDNA sequences (see all 196):

    BQ953738 AI167922 AA505920 AL596487 BF445643 AA504489 AL542196 CK429660 
    AA808267 BU581677 BI492129 AA284865 AK123842 CA313672 AA420431 AW273428 
    AA257953 AI472063 AI612940 AA227378 AB028963 BU739072 AA227158 AK092646 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MON2 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22a ·
    SP1:                    -           -                                                                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                    -     -     -     -     -                                                                                                               
    SP5:                                                                                                                                                            

    ExUns: 22b · 22c ^ 23a · 23b ^ 24a · 24b · 24c ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32a · 32b
    SP1:                                                                                                                                    
    SP2:                                            -                                                           -     -                     
    SP3:                                                                    -     -                             -     -                     
    SP4:                                                                                                                                    
    SP5:        -                                                                                                                           


    ECgene alternative splicing isoforms for MON2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MON2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAACACAGC
    MON2 Expression
    About this image


    See MON2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MON2

    SOURCE GeneReport for Unigene cluster: Hs.389378
        SABiosciences Custom PCR Arrays for MON2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for MON2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MON2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MON2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MON2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MON2 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mon21 , 5 MON2 homolog (yeast)1, 5 86.23(n)1
    95.15(a)1
      10 (72.15 cM)5
    670741  NM_001163024.11  NP_001156496.11 
     1229920615 
    chicken
    (Gallus gallus)
    Aves MON21 MON2 homolog (S. cerevisiae) 83.53(n)
    93.88(a)
      417818  NM_001199605.1  NP_001186534.1 
    lizard
    (Anolis carolinensis)
    Reptilia MON26
    Uncharacterized protein
    92(a)
    1 ↔ 1
    5(51082174-51134587)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ068287.12   -- 81.44(n)    BJ068287.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc16c072 Transcribed sequences 70.9(n)    57047103 
    fruit fly
    (Drosophila melanogaster)
    Insecta mon21 CG8683-PB 54.68(n)
    51.56(a)
      326157  NM_001038795.2  NP_001033884.2 
    worm
    (Caenorhabditis elegans)
    Secernentea mon-21 Protein MON-2 48.33(n)
    35.97(a)
      178153  NM_069894.3  NP_502295.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MON2(YNL297C)4 Peripheral membrane protein with a role in endocytosis more   --   14(76583-71673) 855420  NP_014102.1 


    ENSEMBL Gene Tree for MON2 (if available)
    TreeFam Gene Tree for MON2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2425 SNPs in MON2 are shown (see all 2425)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345919451,2
    C--59936118(+) GTTGATTT/-TAATA 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs105548531,2
    C--59969864(+) CATGG-/CA    
       T
    /TCA
    TTGGA
    2 -- int1 cds11CSA 2
    rs1443441961,2
    --62858616(+) AGAAGC/TATTGT 1 -- us2k10--------
    rs1833159371,2
    --62858642(+) TCCAAC/TTGCAT 1 -- us2k10--------
    rs1478230111,2
    --62858832(+) TGCCTA/GTAATC 1 -- us2k10--------
    rs1879543311,2
    --62858837(+) GTAATC/GCCAGC 1 -- us2k10--------
    rs1130394991,2
    C,F--62858856(+) AGGTCG/AAGGTG 1 -- us2k12Minor allele frequency- A:0.03CSA WA 120
    rs1162143901,2
    C,F--62858963(+) GCCTGC/TGGTGT 1 -- us2k11Minor allele frequency- T:0.18WA 118
    rs1413746091,2
    --62859027(+) CTGAGC/TTCAGT 1 -- us2k10--------
    rs1914645161,2
    --62859050(+) GCCTGA/GGCAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MON2 (62860597 - 62991363 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for MON2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2658375CNV Deletion23128226
    esv2745966CNV Deletion23290073
    esv274602CNV Insertion20981092
    esv268651CNV Insertion20981092
    nsv739CNV Insertion18451855
    nsv740CNV Insertion18451855
    dgv1433n71CNV Loss21882294
    nsv821671CNV Loss15273396
    nsv469418CNV Loss19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MON2
    DNA2.0 Custom Variant and Variant Library Synthesis for MON2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for MON2:    About MalaCards
    leishmaniasis    cutaneous leishmaniasis    visceral leishmaniasis

    2 diseases from the University of Copenhagen DISEASES database for MON2:
    Visceral leishmaniasis     Cutaneous leishmaniasis

    MON2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

    Export disorders for MON2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MON2 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with MON2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. (PubMed id 16301316)1, 2, 3 Gillingham A.K.... Munro S. (2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
    4. Loci associated with N-glycosylation of human immunogl obulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (2013)
    5. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    6. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PubMed id 22678362)1 Stehling O....Lill R. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles. (PubMed id 21450827)1 Tomita Y....Kawaoka Y. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23041 HGNC: 29177 AceView: KIAA1040 Ensembl:ENSG00000061987 euGenes: HUgn23041
    ECgene: MON2 H-InvDB: MON2

    (According to HUGE)
    About This Section
    HUGE: KIAA1040

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MON2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MON2 gene:
    Search GeneIP for patents involving MON2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MON2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MON2  
     OriGene qSTAR qPCR primer pairs in human, mouse for MON2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for MON2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MON2   OriGene Custom Protein Services for MON2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MON2
     QIAGEN SeqTarget long-range PCR primers for resequencing MON2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MON2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MON2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MON2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MON2
     GenScript Custom Purified and Recombinant Proteins Services for MON2 GenScript cDNA clones with any tag delivered in your preferred vector for MON2
     GenScript Custom Assay Services for MON2 GenScript Custom Superior Antibodies Services for MON2
     GenScript Custom overexpressing Cell Line Services for MON2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MON2 promoter
     Search Chromatin IP Primers for MON2
     RT2 qPCR Primer Assay in human, mouse, rat MON2
     Search GNC Networks for MON2
     SABiosciences Custom PCR Arrays for MON2
     Search Tocris compounds for MON2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MON2 antibodies
     Antibodies for MON2
     See all of Abcam's Antibodies, Kits and Proteins for MON2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for MON2
     Antibodies for MON2
     ELISAs for MON2
     CLIAs for MON2
     Search LifeMap BioReagents cell lines for MON2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON2
     SwitchGear 3'UTR luciferase reporter plasmids for MON2
     SwitchGear Promoter luciferase reporter plasmids for MON2
     Search ThermoFisher Antibodies for MON2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for MON2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MON2
    Customized:
     lentivirus for stable overexpression
     lentivirus expression plasmids for stable overexpression
     adenovirus for overexpression of MON2
     LSBio Antibodies in human, mouse, rat for MON2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MON2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4