Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneAnalytics
- GeneLoc
- GenesLikeMe
- VarElect
- PathCards
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

MON1B Gene

protein-coding GIFtS: 50
GCID: GC16P077224

MON1 Secretory Trafficking Family Member B

(Previous name: MON1 homolog B (yeast))

Try our

MalaCards

disease database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
MON1 Secretory Trafficking Family Member B¹ ²		SRG1² ⁵
HSRG1² ³		KIAA0872³ ⁵
SAND2² ³		MON1 Homolog B (Yeast)¹
HSV-1 Stimulation-Related Gene 1 Protein² ³		MON1 Homolog B²
HSV-I Stimulating-Related Protein² ³		Vacuolar Fusion Protein MON1 Homolog B²

External Ids:	HGNC: 25020¹	Entrez Gene: 22879²	Ensembl: ENSG00000103111⁷	OMIM: 608954⁵	UniProtKB: Q7L1V2³

Export aliases for MON1B gene to outside databases

Previous GC identifers: GC16P075783 GC16P062981

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for MON1B Gene:

MON1B (MON1 secretory trafficking family member B) is a protein-coding gene. An important paralog of this gene is MON1A.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

RefSeq DNA sequence at NCBI GenBank:

NC_000016.9 NC_018927.2 NT_010498.16

Regulatory elements:

Regulatory transcription factor binding sites in the MON1B gene promoter:
AhR NRSF form 1 CUTL1 NRSF form 2 C/EBPalpha Arnt E47 CHOP-10 FOXO1a FOXO1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MON1B promoter sequence

Search Chromatin IP Primers for MON1B

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MON1B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.1 Ensembl cytogenetic band: 16q23.1 HGNC cytogenetic band: 16q23.1

MON1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MON1B gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P077224: view genomic region (about GC identifiers)

Start:	77,224,732 bp from pter	End:	77,236,302 bp from pter
Size:	11,571 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MON1B_HUMAN, Q7L1V2 (See protein sequence)

Recommended Name: Vacuolar fusion protein MON1 homolog B

Size: 547 amino acids; 59217 Da

Secondary accessions: O94949

Explore the universe of human proteins at neXtProt for MON1B: NX_Q7L1V2

Explore proteomics data for MON1B at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See MON1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts):

NP_001273568.1 NP_001273569.1 NP_055755.1

ENSEMBL proteins:

ENSP00000456038 ENSP00000248248 ENSP00000457858 ENSP00000455376 ENSP00000457542

ENSP00000455641 ENSP00000404053 ENSP00000444881 ENSP00000324833

MON1B Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for MON1B OriGene Protein Over-expression Lysate for MON1B OriGene MassSpec for MON1B OriGene Custom Protein Services for MON1B
	GenScript Custom Purified and Recombinant Proteins Services for MON1B
	Novus Biologicals MON1B Proteins Novus Biologicals MON1B Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for MON1B
	Search eBioscience for Proteins for MON1B
	antibodies-online proteins for MON1B (5 products)
	antibodies-online peptides for MON1B

MON1B Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for MON1B
	Novus Biologicals MON1B Antibodies
	Abcam antibodies for MON1B
	Cloud-Clone Corp. Antibodies for MON1B
	Search ThermoFisher Antibodies for MON1B
	antibodies-online antibodies for MON1B (12 products)

MON1B Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for MON1B
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MON1B
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for MON1B Cloud-Clone Corp. CLIAs for MON1B
	Search eBioscience for ELISAs for MON1B
	antibodies-online kits for MON1B (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

1 InterPro protein domain:

IPR004353 Vacuolar_fusion_protein_MON1

Graphical View of Domain Structure for InterPro Entry Q7L1V2

ProtoNet protein and cluster: Q7L1V2

1 Blocks protein domain: IPB004353 Saccharomyces cerevisiae 73.5kDa hypothetical protein signature

UniProtKB/Swiss-Prot: MON1B_HUMAN, Q7L1V2

Similarity: Belongs to the MON1/SAND family

Find genes that share domains with MON1B About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

UniProtKB/Swiss-Prot Summary: MON1B_HUMAN, Q7L1V2

Induction: Induced in fibroblast KMB17 cells by HSV-1

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--

Find genes that share ontologies with MON1B About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for MON1B

miRNA Products:		miRTarBase miRNAs that target MON1B: hsa-mir-99a-5p (MIRT048627), hsa-mir-93-3p (MIRT038816)

		Block miRNA regulation of human, mouse, rat MON1B using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate MON1B (see all 13):
		hsa-miR-4300 hsa-miR-657 hsa-miR-15a hsa-miR-497 hsa-miR-1291 hsa-miR-920 hsa-miR-3142 hsa-miR-424

		SwitchGear 3'UTR luciferase reporter plasmid: MON1B 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MON1B
		Predesigned siRNA for gene silencing in human, mouse, rat MON1B

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MON1B

Clone Products:		OriGene clones in human, mouse for MON1B (see all 8) OriGene ORF clones in mouse, rat for MON1B OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MON1B (NM_014940)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON1B
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON1B

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MON1B
		Browse ESI BIO Cell Lines and PureStem Progenitors for MON1B

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON1B

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	3
cytosol	2
endosome	1
extracellular	1
peroxisome	1

About this image

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for MON1B
Interactions:

Search GeneGlobe Interaction Network for MON1B

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for MON1B (Q7L1V2^{1, 3} ENSP00000248248⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 39)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
VPS18	Q9P253¹^,³, ENSP00000220509⁴	EBI-2655311,EBI-1053363 I2D: score=1 STRING: ENSP00000220509
FYCO1	Q9BQS8³, ENSP00000296137⁴	I2D: score=3 STRING: ENSP00000296137
VPS16	Q9H269³, ENSP00000369810⁴	I2D: score=1 STRING: ENSP00000369810
MON1A	Q86VX9³, ENSP00000296473⁴	I2D: score=1 STRING: ENSP00000296473
VPS33A	Q96AX1³, ENSP00000267199⁴	I2D: score=1 STRING: ENSP00000267199

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for MON1B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for MON1B gene (3 alternative transcripts):

NM_001286639.1 NM_001286640.1 NM_014940.3

Unigene Cluster for MON1B:

MON1 homolog B (yeast)

Hs.513743 [show with all ESTs]

Unigene Representative Sequence: AB020679

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000569610 ENST00000248248(uc002fez.3 uc010vnf.2 uc010vng.2)

ENST00000567291 ENST00000563612 ENST00000563279 ENST00000566963 ENST00000564006

ENST00000439557 ENST00000545553 ENST00000566455(uc002ffa.3) ENST00000320859

miRNA Products:		Block miRNA regulation of human, mouse, rat MON1B using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate MON1B (see all 13):
		hsa-miR-4300 hsa-miR-657 hsa-miR-15a hsa-miR-497 hsa-miR-1291 hsa-miR-920 hsa-miR-3142 hsa-miR-424

		SwitchGear 3'UTR luciferase reporter plasmid: MON1B 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MON1B
		Predesigned siRNA for gene silencing in human, mouse, rat MON1B

Clone Products:		OriGene clones in human, mouse for MON1B (see all 8) OriGene ORF clones in mouse, rat for MON1B OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MON1B (NM_014940)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MON1B
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON1B

Primer Products:		OriGene qPCR primer pairs and template standards for MON1B OriGene qSTAR qPCR primer pairs in human, mouse for MON1B
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MON1B
		QuantiTect SYBR Green Assays in human, mouse, rat MON1B
		QuantiFast Probe-based Assays in human, mouse, rat MON1B

Additional mRNA sequence:

AB020679.1 AF442486.1 AK023374.1 AK023896.1 AK293392.1 AK296467.1 BC024277.1

8 DOTS entries:

DT.454740 DT.97845873 DT.100736117 DT.410177 DT.97837739 DT.120666081 DT.120666109 DT.95375547

Selected AceView cDNA sequences (see all 254):

BQ071055 AW002072 BU185253 BX345691 BX457718 AA258904 BE464728 BM837466

AA411034 NM_014940 BM541667 BQ417312 BU507596 BC024277 CD516480 BM469754

AI298133 BP341212 BQ647666 AI275496 AI422836 AA025370 BU501529 CA488947

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for MON1B (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2a	·	2b	^	3a	·	3b	·	3c	·	3d	·	3e	·	3f	^	4a	·	4b	·	4c	·	4d	^	5a	·	5b	^	6a	·	6b	·	6c
SP1:																	-												-
SP2:																	-										-		-		-		-		-		-
SP3:																													-
SP4:																	-												-
SP5:																	-

ECgene alternative splicing isoforms for MON1B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

MON1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CGTGCTGAAA

About this image

MON1B Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

MON1B Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.513743

Custom PCR Arrays for MON1B

Primer Products:		OriGene qPCR primer pairs and template standards for MON1B OriGene qSTAR qPCR primer pairs in human, mouse for MON1B
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MON1B
		QuantiTect SYBR Green Assays in human, mouse, rat MON1B
		QuantiFast Probe-based Assays in human, mouse, rat MON1B

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON1B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of eukaryotes.

Orthologs for MON1B gene from Selected species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mon1b^{1 , 5}	MON1 homolog b (yeast)^{1, 5}	85.04(n)¹ 88.46(a)¹		8 (59.65 cM)⁵ 270096¹ NM_173015.3¹ NP_766603.1¹ 113635586⁵
lizard (Anolis carolinensis)	Reptilia	MON1B⁶	MON1 secretory trafficking family member B	50(a)	1 ↔ 1	2(69091083-69114383)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.11528²	Transcribed sequence with weak similarity to protein more	74.42(n)		BQ388616.1
zebrafish (Danio rerio)	Actinopterygii	Dr.26940²	Transcribed sequence with weak similarity to protein more	78.3(n)		57081199
fruit fly (Drosophila melanogaster)	Insecta	CG11926⁶	--	33(a)	1 → many	2L(4850641-4852640)
worm (Caenorhabditis elegans)	Secernentea	sand-1⁶	Protein SAND-1 (sand-1) mRNA, complete cds	26(a)	1 → many	IV(5366867-5368866) WBGene00018321
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	MON1⁶	Protein required for fusion of cvt-vesicles and au...	18(a)	1 → many	VII(274780-276714) YGL124C
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G28390¹	AT2G28390	44.72(n) 34.88(a)		817387 NM_128399.3 NP_029426.1
rice (Oryza sativa)	Liliopsida	Os01g0976000¹	Os01g0976000	43.6(n) 33.1(a)		4324304 NM_001052098.1 NP_001045563.2

ENSEMBL Gene Tree for MON1B (if available)
TreeFam Gene Tree for MON1B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

Paralogs for MON1B gene

MON1A²

1 SIMAP similar gene for MON1B using alignment to 9 protein entries: MON1B_HUMAN (see all proteins):

MON1A

Find genes that share paralogs with MON1B About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144293162^1,2		--	77222843(+)	`TCTGCC/TATTTT`	1	--	us2k¹		0	--	--	--	--
rs7185297^1,2	C,F,A,H	--	77222866(+)	`ATCTTC/TAAAGT`	1	--	us2k¹		26		NS EA NA WA CSA	2251
rs191917776^1,2		--	77223008(+)	`GCTGGG/TAACTG`	1	--	us2k¹		0	--	--	--	--
rs9930541^1,2	C,F,A,H	--	77223025(+)	`gcaaaG/Cctgcc`	1	--	us2k¹		12		NA WA CSA EA	379
rs114235673^1,2		--	77223120(+)	`GCTGCA/CAGATC`	1	--	us2k¹		0	--	--	--	--
rs6564405^1,2	C,F,A	--	77223171(+)	`gtaaaC/Ttgata`	1	--	us2k¹		11		NA WA CSA EA	373
rs7185889^1,2	C,F,A	--	77223180(+)	`tagttC/Tatctt`	1	--	us2k¹		11		NA WA CSA EA	373
rs112072615^1,2	C,F	--	77223195(+)	`GGTGCG/CAGACA`	1	--	us2k¹		1		CSA	2
rs184716196^1,2		--	77223314(+)	`ATTCCC/TCTACT`	1	--	us2k¹		0	--	--	--	--
rs187635215^1,2		--	77223323(+)	`CTCCCC/TTGATA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MON1B (77224732 - 77236302 bp)

Structural Variations
Database of Genomic Variants (DGV) 4 variations for MON1B: About this table

Variant ID	Type	Subtype	PubMed ID
esv25858	CNV	Loss	19812545
nsv523187	CNV	Loss	19592680
nsv827756	CNV	Gain	20364138
dgv2918n71	CNV	Gain	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing MON1B

DNA2.0 Custom Variant and Variant Library Synthesis for MON1B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

OMIM gene information: 608954 OMIM disorders: --

Find genes that share disorders with MON1B About GenesLikeMe

Genetic Association Database (GAD): MON1B
Human Genome Epidemiology (HuGE) Navigator: MON1B (3 documents)

Export disorders for MON1B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for MON1B gene, integrated from 10 sources (see all 17):
(articles sorted by number of sources associating them with MON1B)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)^{1, 2, 3} Nagase T.... Ohara O. (DNA Res. 1998)
Identification of a novel human MON1/SAND family protein in human fibroblasts induced by herpes simplex virus 1 binding. (PubMed id 12828340)^{1, 2, 9} Dong S.Z.... Li Q.H. (Acta Virol. 2003)
Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)^{1, 4} Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PubMed id 19844255)^{1, 4} Dastani Z....Genest J. (Eur. J. Hum. Genet. 2010)
Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)^{1, 4} Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (Cell 2012)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)¹ Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)² Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
Network organization of the human autophagy system. (PubMed id 20562859)¹ Behrends C....Harper J.W. (Nature 2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 22879	HGNC: 25020	AceView: HSRG1	Ensembl:ENSG00000103111	euGenes: HUgn22879
ECgene: MON1B	H-InvDB: MON1B

(According to HUGE)
About This Section

TryGeneCards Plus

HUGE: KIAA0872

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for MON1B	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MON1B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for MON1B gene:
Search GeneIP for patents involving MON1B

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for MON1B
	OriGene qPCR primer pairs and template standards for MON1B		OriGene Protein Over-expression Lysate for MON1B
	OriGene MassSpec for MON1B		OriGene clones in human, mouse for MON1B
	OriGene qSTAR qPCR primer pairs in human, mouse for MON1B		OriGene Purified Protein for MON1B
	OriGene ORF clones in mouse, rat for MON1B		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for MON1B		OriGene Custom Protein Services for MON1B

	Block miRNA regulation of human, mouse, rat MON1B using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing MON1B
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MON1B		Predesigned siRNA for gene silencing in human, mouse, rat MON1B
	QuantiFast Probe-based Assays in human, mouse, rat MON1B		QuantiTect SYBR Green Assays in human, mouse, rat MON1B
	Custom PCR Arrays for MON1B		Search Chromatin IP Primers for MON1B
	Pre-validated RT² qPCR Primer Assay in human, mouse, rat MON1B		Search GeneGlobe Interaction Network for MON1B
	Regulatory tfbs in MON1B promoter

	GenScript Custom Purified and Recombinant Proteins Services for MON1B		GenScript cDNA clones with any tag delivered in your preferred vector for MON1B
	GenScript Custom Assay Services for MON1B		GenScript Custom overexpressing Cell Line Services for MON1B
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for MON1B

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	MON1B antibodies
	MON1B proteins
	MON1B lysates

	Antibodies for MON1B
	See all of Abcam's Antibodies, Kits and Proteins for MON1B
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for MON1B
	Antibodies for MON1B
	ELISAs for MON1B
	CLIAs for MON1B

Browse ESI BIO Cell Lines and PureStem Progenitors for MON1B

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MON1B

	SwitchGear 3'UTR luciferase reporter plasmids for MON1B
	SwitchGear Promoter luciferase reporter plasmids for MON1B

Search ThermoFisher Antibodies for MON1B

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MON1B

Browse compounds at ApexBio

Search Addgene for plasmids for MON1B

	Search eBioscience for proteins for MON1B
	Search eBioscience for elisas for MON1B
	eBioscience FlowRNA Probe Sets

genOway: Develop your customized and physiologically relevant rodent model for MON1B

	antibodies-online antibodies for MON1B (12 products)
	antibodies-online kits for MON1B (4 products)
	antibodies-online peptides for MON1B
	antibodies-online proteins for MON1B (5 products)

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MON1B gene at Home site.

Version: 3.12.304 29 Jan 2015
hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

MON1B Gene

MON1 Secretory Trafficking Family Member B

Aliases
for MON1B gene

Summaries
for MON1B gene

Genomic Views
for MON1B gene

Proteins
for MON1B gene

MON1B Human Recombinant Protein Products:

MON1B Antibody Products:

MON1B Assay Products:

Domains /
Families
for MON1B gene

Function
for MON1B gene

Localization
for MON1B gene

Pathways & Interactions
for MON1B gene

Drugs & Compounds
for MON1B gene

Transcripts
for MON1B gene

Expression
for MON1B gene

Orthologs
for MON1B gene

Paralogs
for MON1B gene

Genomic Variants
for MON1B gene

Disorders / Diseases
for MON1B gene

Publications
for MON1B gene

External Searches for MON1B gene

Genome Databases showing MON1B gene

Other Databases showing MON1B gene

Specialized Databases showing MON1B gene

Intellectual Property
for MON1B gene

Products
for MON1B gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

MON1B Gene

MON1 Secretory Trafficking Family Member B

Aliasesfor MON1B gene

Summariesfor MON1B gene

Genomic Viewsfor MON1B gene

Proteinsfor MON1B gene

MON1B Human Recombinant Protein Products:

MON1B Antibody Products:

MON1B Assay Products:

Domains /Familiesfor MON1B gene

Functionfor MON1B gene

Localizationfor MON1B gene

Pathways & Interactionsfor MON1B gene

Drugs & Compoundsfor MON1B gene

Transcriptsfor MON1B gene

Expression for MON1B gene

Orthologsfor MON1B gene

Paralogsfor MON1B gene

Genomic Variantsfor MON1B gene

Disorders / Diseasesfor MON1B gene

Publicationsfor MON1B gene

External Searches for MON1B gene

Genome Databases showing MON1B gene

Other Databases showing MON1B gene

Specialized Databases showing MON1B gene

Intellectual Propertyfor MON1B gene

Productsfor MON1B gene

View Random Gene

Aliases
for MON1B gene

Summaries
for MON1B gene

Genomic Views
for MON1B gene

Proteins
for MON1B gene

Domains /
Families
for MON1B gene

Function
for MON1B gene

Localization
for MON1B gene

Pathways & Interactions
for MON1B gene

Drugs & Compounds
for MON1B gene

Transcripts
for MON1B gene

Expression
for MON1B gene

Orthologs
for MON1B gene

Paralogs
for MON1B gene

Genomic Variants
for MON1B gene

Disorders / Diseases
for MON1B gene

Publications
for MON1B gene

Intellectual Property
for MON1B gene

Products
for MON1B gene