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Aliases for MON1B Gene

Aliases for MON1B Gene

  • MON1 Secretory Trafficking Family Member B 2 3
  • HSV-1 Stimulation-Related Gene 1 Protein 3 4
  • HSV-I Stimulating-Related Protein 3 4
  • KIAA0872 4 6
  • HSRG1 3 4
  • SAND2 3 4
  • SRG1 3 6
  • Vacuolar Fusion Protein MON1 Homolog B 3
  • MON1 Homolog B (Yeast) 2
  • MON1 Homolog B 3

External Ids for MON1B Gene

Previous GeneCards Identifiers for MON1B Gene

  • GC16P075783
  • GC16P062981

Summaries for MON1B Gene

GeneCards Summary for MON1B Gene

MON1B (MON1 Secretory Trafficking Family Member B) is a Protein Coding gene. An important paralog of this gene is MON1A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MON1B Gene

Genomics for MON1B Gene

Regulatory Elements for MON1B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MON1B Gene

77,190,835 bp from pter
77,202,405 bp from pter
11,571 bases
Plus strand

Genomic View for MON1B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MON1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MON1B Gene

Proteins for MON1B Gene

  • Protein details for MON1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Vacuolar fusion protein MON1 homolog B
    Protein Accession:
    Secondary Accessions:
    • B4DDZ0
    • O94949

    Protein attributes for MON1B Gene

    547 amino acids
    Molecular mass:
    59217 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MON1B Gene


neXtProt entry for MON1B Gene

Proteomics data for MON1B Gene at MOPED

Post-translational modifications for MON1B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MON1B Gene

Domains for MON1B Gene

Suggested Antigen Peptide Sequences for MON1B Gene

Graphical View of Domain Structure for InterPro Entry



  • Q7L1V2
  • Belongs to the MON1/SAND family.
genes like me logo Genes that share domains with MON1B: view

No data available for Gene Families for MON1B Gene

Function for MON1B Gene

Molecular function for MON1B Gene

UniProtKB/Swiss-Prot Induction:
Induced in fibroblast KMB17 cells by HSV-1.

Gene Ontology (GO) - Molecular Function for MON1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20434987
genes like me logo Genes that share ontologies with MON1B: view

Animal Model Products

miRNA for MON1B Gene

miRTarBase miRNAs that target MON1B

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MON1B Gene

Localization for MON1B Gene

Subcellular locations from

Jensen Localization Image for MON1B Gene COMPARTMENTS Subcellular localization image for MON1B gene
Compartment Confidence
nucleus 3
cytosol 2
endosome 1
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for MON1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0012505 endomembrane system IBA --
genes like me logo Genes that share ontologies with MON1B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MON1B Gene

Pathways for MON1B Gene

SuperPathways for MON1B Gene

No Data Available

Gene Ontology (GO) - Biological Process for MON1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016192 vesicle-mediated transport IBA --
genes like me logo Genes that share ontologies with MON1B: view

No data available for Pathways by source for MON1B Gene

Transcripts for MON1B Gene

Unigene Clusters for MON1B Gene

MON1 homolog B (yeast):
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MON1B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MON1B Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - -
SP2: - - - - - - -
SP3: -
SP4: - -
SP5: -
SP6: - -
SP7: - -
SP9: -

Relevant External Links for MON1B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MON1B Gene

mRNA expression in normal human tissues for MON1B Gene

Protein differential expression in normal tissues for MON1B Gene

This gene is overexpressed in Breast (33.0) and Peripheral blood mononuclear cells (9.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MON1B Gene

SOURCE GeneReport for Unigene cluster for MON1B Gene Hs.513743

genes like me logo Genes that share expressions with MON1B: view

Expression partners for MON1B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MON1B Gene

Orthologs for MON1B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MON1B Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia MON1B 35
  • 88.34 (n)
  • 90.29 (a)
MON1B 36
  • 89 (a)
(Mus musculus)
Mammalia Mon1b 35
  • 85.04 (n)
  • 88.46 (a)
Mon1b 16
Mon1b 36
  • 88 (a)
(Pan troglodytes)
Mammalia MON1B 35
  • 99.45 (n)
  • 99.63 (a)
MON1B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Mon1b 35
  • 85.46 (n)
  • 90.64 (a)
(Bos Taurus)
Mammalia MON1B 36
  • 77 (a)
(Monodelphis domestica)
Mammalia MON1B 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia MON1B 36
  • 48 (a)
(Anolis carolinensis)
Reptilia MON1B 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11528 35
(Danio rerio)
Actinopterygii Dr.26940 35
wu:fc54b10 35
  • 63.14 (n)
  • 62.07 (a)
MON1B (1 of 2) 36
  • 51 (a)
MON1B (2 of 2) 36
  • 46 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11926 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea sand-1 36
  • 26 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MON1 36
  • 18 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G28390 35
  • 44.72 (n)
  • 34.88 (a)
(Oryza sativa)
Liliopsida Os01g0976000 35
  • 43.6 (n)
  • 33.1 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
Species with no ortholog for MON1B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MON1B Gene

Gene Tree for MON1B (if available)
Gene Tree for MON1B (if available)

Paralogs for MON1B Gene

Paralogs for MON1B Gene

Selected SIMAP similar genes for MON1B Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with MON1B: view

Variants for MON1B Gene

Sequence variations from dbSNP and Humsavar for MON1B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs2017197 -- 77,195,772(+) TCCAC(C/G)AAACA intron-variant
rs2161715 -- 77,190,683(+) GGACT(G/T)ACGCT upstream-variant-2KB
rs2232492 -- 77,190,641(+) TCTGG(C/G)AGAGC upstream-variant-2KB
rs2232493 -- 77,190,788(+) CAACG(C/T)ACAGT upstream-variant-2KB
rs2232494 -- 77,190,812(+) TGGCG(A/G)GGGGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MON1B Gene

Variant ID Type Subtype PubMed ID
dgv2918n71 CNV Gain 21882294
nsv827756 CNV Gain 20364138
esv25858 CNV Loss 19812545
nsv523187 CNV Loss 19592680

Relevant External Links for MON1B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MON1B Gene

Disorders for MON1B Gene

Relevant External Links for MON1B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for MON1B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MON1B Gene

Publications for MON1B Gene

  1. Identification of a novel human MON1/SAND family protein in human fibroblasts induced by herpes simplex virus 1 binding. (PMID: 12828340) Dong S.Z. … Li Q.H. (Acta Virol. 2003) 3 4 23
  2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PMID: 19844255) Dastani Z. … Genest J. (Eur. J. Hum. Genet. 2010) 3 48
  5. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M. … Yamada Y. (Am. J. Hypertens. 2010) 3 48

Products for MON1B Gene

Sources for MON1B Gene

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