Aliases for MON1A Gene
External Ids for MON1A Gene
Previous GeneCards Identifiers for MON1A Gene
GeneCards Summary for MON1A Gene
MON1A (MON1 Homolog A, Secretory Trafficking Associated) is a Protein Coding gene. Diseases associated with MON1A include Extrahepatic Bile Duct Adenocarcinoma and Space Motion Sickness. Among its related pathways are RAB GEFs exchange GTP for GDP on RABs and Vesicle-mediated transport. An important paralog of this gene is MON1B.
UniProtKB/Swiss-Prot for MON1A Gene
Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).