Aliases for MON1A Gene
External Ids for MON1A Gene
Previous GeneCards Identifiers for MON1A Gene
GeneCards Summary for MON1A Gene
MON1A (MON1 Homolog A, Secretory Trafficking Associated) is a Protein Coding gene. Diseases associated with MON1A include Extrahepatic Bile Duct Adenocarcinoma and Space Motion Sickness. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. An important paralog of this gene is MON1B.
UniProtKB/Swiss-Prot for MON1A Gene
Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).