Aliases for MOGAT3 Gene
External Ids for MOGAT3 Gene
Previous GeneCards Identifiers for MOGAT3 Gene
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 18.104.22.168) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
GeneCards Summary for MOGAT3 Gene
MOGAT3 (Monoacylglycerol O-Acyltransferase 3) is a Protein Coding gene. Among its related pathways are Fat digestion and absorption and Metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and diacylglycerol O-acyltransferase activity. An important paralog of this gene is DGAT2.
UniProtKB/Swiss-Prot for MOGAT3 Gene
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.