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MOGAT3 Gene

protein-coding   GIFtS: 51
GCID: GC07M100838

Monoacylglycerol O-Acyltransferase 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Monoacylglycerol O-Acyltransferase 31 2 3     DGAT2L72 3
MGAT32 3 5     2-Acylglycerol O-Acyltransferase 32
Acyl-CoA:Monoacylglycerol Acyltransferase 32 3     Acyl Coenzyme A:Monoacylglycerol Acyltransferase 32
Diacylglycerol Acyltransferase 2-Like Protein 72 3     EC 2.3.1.203
Diacylglycerol O-Acyltransferase Candidate 72 3     EC 2.3.1.223
DC72 3     hDC73

External Ids:    HGNC: 232491   Entrez Gene: 3466062   Ensembl: ENSG000001063847   OMIM: 6101845   UniProtKB: Q86VF53   

Export aliases for MOGAT3 gene to outside databases

Previous GC identifers: GC07M100400 GC07M100432 GC07M100625 GC07M095431


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MOGAT3 Gene:
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from
2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 (PubMed 12618427)).(supplied by OMIM, Mar 2008)

GeneCards Summary for MOGAT3 Gene:
MOGAT3 (monoacylglycerol O-acyltransferase 3) is a protein-coding gene. GO annotations related to this gene include diacylglycerol O-acyltransferase activity and 2-acylglycerol O-acyltransferase activity. An important paralog of this gene is DGAT2.

UniProtKB/Swiss-Prot: MOGT3_HUMAN, Q86VF5
Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to
catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates.
Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small
intestine by catalyzing the resynthesis of triacylglycerol in enterocytes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MOGAT3 gene promoter:
         p53   HTF   Olf-1   HNF-4alpha2   NF-kappaB   FOXL1   HNF-4alpha1   NF-kappaB2   Pax-4a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMOGAT3 promoter sequence
   Search Chromatin IP Primers for MOGAT3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MOGAT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

MOGAT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MOGAT3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M100838:  view genomic region     (about GC identifiers)

Start:
100,838,288 bp from pter      End:
100,844,302 bp from pter
Size:
6,015 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 100,197,397-100,202,689     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MOGT3_HUMAN, Q86VF5 (See protein sequence)
Recommended Name: 2-acylglycerol O-acyltransferase 3  
Size: 341 amino acids; 38730 Da
Sequence caution: Sequence=AAD45832.1; Type=Erroneous gene model prediction;
Secondary accessions: Q496A6 Q496A7 Q496A8 Q9UDW7
Alternative splicing: 3 isoforms:  Q86VF5-1   Q86VF5-2   Q86VF5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MOGAT3: NX_Q86VF5

Explore proteomics data for MOGAT3 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn126

  • See MOGAT3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001274076.1  NP_835470.1  

    ENSEMBL proteins: 
     ENSP00000223114   ENSP00000403756   ENSP00000368734  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007130 DAGAT

    Graphical View of Domain Structure for InterPro Entry Q86VF5

    ProtoNet protein and cluster: Q86VF5

    UniProtKB/Swiss-Prot: MOGT3_HUMAN, Q86VF5
    Similarity: Belongs to the diacylglycerol acyltransferase family


    Find genes that share domains with MOGAT3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOGT3_HUMAN, Q86VF5
    Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to
    catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates.
    Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small
    intestine by catalyzing the resynthesis of triacylglycerol in enterocytes
    Catalytic activity: Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol
    Catalytic activity: Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol
    Biophysicochemical properties: Kinetic parameters: Vmax=9.3 nmol/min/mg enzyme with diacylglycerol as substrate;
    Vmax=22.8 nmol/min/mg enzyme with 2-monoacylglycerol as substrate;

         Enzyme Numbers (IUBMB): EC 2.3.1.201 EC 2.3.1.221

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00038462-acylglycerol O-acyltransferase activity IEA--
    GO:0004144diacylglycerol O-acyltransferase activity IEA--
    GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups ----
         
    Find genes that share ontologies with MOGAT3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for MOGAT3:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MOGAT3
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MOGT3_HUMAN, Q86VF5: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with MOGAT3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MOGAT3 About    
    See pathways by source

    SuperPathContained pathways About
    1triacylglycerol biosynthesis
    triacylglycerol biosynthesis0.48
    Triacylglyceride Synthesis0.36
    2Metabolism
    Metabolic pathways0.38
    3Glycerolipid metabolism
    Glycerolipid metabolism
    4Fat digestion and absorption
    Fat digestion and absorption


    Find genes that share SuperPaths with MOGAT3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for MOGAT3
        Triacylglyceride Synthesis
    triacylglycerol biosynthesis


    3 Kegg Pathways  (Kegg details for MOGAT3):
        Glycerolipid metabolism
    Metabolic pathways
    Fat digestion and absorption

    UniProtKB/Swiss-Prot: MOGT3_HUMAN, Q86VF5
    Pathway: Glycerolipid metabolism; triacylglycerol biosynthesis

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MOGAT3
    Interactions:

        Search GeneGlobe Interaction Network for MOGAT3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MOGAT3 (ENSP000002231144) via UniProtKB, MINT, STRING, and/or I2D (see all 42)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBC1D5ENSP000004029354STRING: ENSP00000402935
    CELENSP000003611514STRING: ENSP00000361151
    DGAT2ENSP000002280274STRING: ENSP00000228027
    DGKDENSP000002640574STRING: ENSP00000264057
    DGKHENSP000003375724STRING: ENSP00000337572
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006071glycerol metabolic process IEA--
    GO:0019432triglyceride biosynthetic process IEA--

    Find genes that share ontologies with MOGAT3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for MOGAT3 (MOGT3)

    Selected HMDB Compounds for MOGAT3 (see all 1226)    About this table
    CompoundSynonyms CAS #PubMed Ids
    DG(16:0e/18:0/0:0)2-Octadecanoyl-1-hexadecyl-sn-glycerol (see all 2)--12486725
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Arachidonylglycerol2-Arachidonyl glycerol;(all-Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoic acid (see all 21)53847-30-6--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MOGAT3 gene (2 alternative transcripts): 
    NM_001287147.1  NM_178176.3  

    Unigene Cluster for MOGAT3:

    Monoacylglycerol O-acyltransferase 3
    Hs.512217  [show with all ESTs]
    Unigene Representative Sequence: AY229854
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000223114(uc003uyc.3 uc010lhr.3) ENST00000440203 ENST00000379423

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    Additional mRNA sequence: 

    AY229854.1 AY358200.1 BC100953.1 BC100954.1 BC100955.1 

    2 DOTS entries:

    DT.99941420  DT.40273699 

    6 AceView cDNA sequences:

    AY358200 BE042458 NM_178176 AI207424 AY229854 CA432791 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MOGAT3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:                                    
    SP2:                                    
    SP3:                          -         


    ECgene alternative splicing isoforms for MOGAT3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MOGAT3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCCAATAA
    MOGAT3 Expression
    About this image


    MOGAT3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
    MOGAT3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MOGAT3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.512217

    UniProtKB/Swiss-Prot: MOGT3_HUMAN, Q86VF5
    Tissue specificity: Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower
    level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and
    trachea. Expressed at very low level in liver

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MOGAT3 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia MOGAT31 monoacylglycerol O-acyltransferase 3 79.41(n)
    73.7(a)
      608245  XM_845212.3  XP_850305.2 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    44(a)
    many ↔ many
    4(1197356-1203620)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    38(a)
    many ↔ many
    GL344027.1(35241-39997)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia awat11 acyl-CoA wax alcohol acyltransferase 1 55.35(n)
    50.78(a)
      100127622  NM_001112975.1  NP_001106446.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mogat3b1 monoacylglycerol O-acyltransferase 3b 55.66(n)
    53.77(a)
      494083  NM_001008626.2  NP_001008626.2 


    ENSEMBL Gene Tree for MOGAT3 (if available)
    TreeFam Gene Tree for MOGAT3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MOGAT3 gene
    DGAT22  MOGAT12  DGAT2L62  AWAT22  AWAT12  MOGAT22  
    6 SIMAP similar genes for MOGAT3 using alignment to 1 protein entry:     MOGT3_HUMAN:
    DGAT2    DGAT2L6    AWAT2    AWAT1    MOGAT1    MOGAT2

    Find genes that share paralogs with MOGAT3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MOGAT3 (see all 164)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1930578941,2
    --100838528(+) TCTCGC/TTCTGT 1 -- int10--------
    rs20793341,2
    C,F--100838569(+) CGGCTG/CACTGC 1 -- int12Minor allele frequency- C:0.50NA CSA 4
    rs132408391,2
    C,F,A--100838732(+) CTCAGT/GTGATC 1 -- int14Minor allele frequency- G:0.43NA CSA 7
    rs1855770961,2
    --100838750(+) CTCGGC/GTTCCC 1 -- int10--------
    rs1136466171,2
    C,F--100838798(+) GCCTAG/CTACAG 1 -- int11Minor allele frequency- C:0.50WA 2
    rs604728731,2
    C--100838815(+) TTTTT-/T/T   
       TTTTT
    GAGAT
    2 -- int1 cds12NA 4
    rs1904846311,2
    --100839027(+) TGAAGC/TCTCAC 1 -- ut310--------
    rs1168159111,2
    C,F--100839202(+) CAGGGG/ACTCAG 1 -- ut311Minor allele frequency- A:0.03WA 118
    rs1385320051,2
    C--100839253(+) GGAAGC/TGGGGA 2 T A mis10--------
    rs2010455961,2
    --100839260(+) GGGACC/GCCACA 2 G syn10--------

    HapMap Linkage Disequilibrium report for MOGAT3 (100838288 - 100844302 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for MOGAT3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    esv2422376CNV Duplication17116639
    esv2422326CNV Duplication17116639
    nsv831075CNV Loss17160897
    nsv831076CNV Loss17160897
    dgv7409n71CNV Loss21882294
    dgv7410n71CNV Loss21882294
    esv2752134CNV Gain17911159

    Human Gene Mutation Database (HGMD): MOGAT3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MOGAT3
    DNA2.0 Custom Variant and Variant Library Synthesis for MOGAT3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610184    OMIM disorders: --


    Find genes that share disorders with MOGAT3           About GenesLikeMe


    Export disorders for MOGAT3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MOGAT3 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with MOGAT3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. (PubMed id 12618427)1, 2, 3, 9 Cheng D.... Feder J.N. (J. Biol. Chem. 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals. (PubMed id 14970677)1, 3 Winter A....Fries R. (Cytogenet. Genome Res. 2003)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures. (PubMed id 12486725)6 Kurz M....Kramer W. (Proteins 2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Toward a complete human genome sequence. (PubMed id 9847074)1 Sulston J.E. and Waterston R. (Genome Res. 1998)
    10. Catalytic properties of MGAT3, a putative triacylgycerol synthase. (PubMed id 17170429)9 Cao J....Shi Y. (J. Lipid Res. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 346606 HGNC: 23249 AceView: MOGAT3 Ensembl:ENSG00000106384 euGenes: HUgn346606
    ECgene: MOGAT3 Kegg: 346606 H-InvDB: MOGAT3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MOGAT3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MOGAT3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MOGAT3 gene:
    Search GeneIP for patents involving MOGAT3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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