MOG Gene
protein-coding GIFtS: 61
GCID: GC06P029624
|
|
myelin oligodendrocyte glycoprotein
| |
Aliases
for MOG gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myelin Oligodendrocyte Glycoprotein1 2 | | MOGIG22 | | NRCLP72 | | MOG Alpha-52 | | MOG Ig-AluB2 | | Myelin-Oligodendrocyte Glycoprotein2 |
Export aliases for MOG gene to outside databasesPrevious GC identifers: GC06P029682 GC06P029395 GC06P029732 GC06P029431 |
Summaries
for MOG gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MOG:
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surfaceof myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination.This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication.Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653Function: Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involvedin completion and/or maintenance of the myelin sheath and in cell-cell communication
Gene Wiki entry for MOG (Myelin oligodendrocyte glycoprotein)
|
Genomic Views
for MOG gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1
- NT_167248.1 NT_167249.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MOG gene promoter:
CREB deltaCREB MRF-2 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for MOG
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOG |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p22-p21.3MOG Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P029624: view genomic region
(about GC identifiers)
Start:
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29,624,758 bp from pter |
End:
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29,640,149 bp from pter |
Size:
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15,392 bases |
Orientation:
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plus strand |
6/7 alternative locations (see all 7):
| Chr6+,ALT_REF_LOCI_4 29,547,377-29,562,765 | Chr6+,ALT_REF_LOCI_1 29,624,887-29,648,577 | Chr6+,ALT_REF_LOCI_5 29,539,370-29,554,754 | | Chr6+,ALT_REF_LOCI_3 29,624,714-29,651,144 | Chr6+,ALT_REF_LOCI_2 29,621,355-29,675,935 | Chr6+,ALT_REF_LOCI_6 29,624,680-29,675,653 | |
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Proteins
for MOG gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653 (See
protein sequence)Recommended Name: Myelin-oligodendrocyte glycoprotein precursor Size: 247 amino acids; 28193 Da
Subunit: Homodimer (By similarity). May form heterodimers between the different isoforms
Subcellular location: Isoform 1: Cell membrane; Multi-pass membrane protein (Potential)
Subcellular location: Isoform 5: Cell membrane; Multi-pass membrane protein (Potential)
Subcellular location: Isoform 2: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 3: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 4: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 6: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 7: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 8: Cell membrane; Single-pass type I membrane protein (Potential)
Subcellular location: Isoform 9: Cell membrane; Single-pass type I membrane protein (Potential)
Caution: Do not confuse myelin-oligodendrocyte glycoprotein (MOG) with oligodendrocyte-myelin glycoprotein (OMG)
1 PDB 3D structure from  and Proteopedia  for MOG:1Q70 (3D)
Secondary accessions: A6NDR4 A8MY31 B0UZR9 O00713 O00714 O00715 Q13054 Q13055 Q14855 Q5JNY1 Q5JNY4Q5SSB5 Q5SSB6 Q5STM0 Q5STM5 Q5SUK7 Q5SUK8 Q5SUK9 Q5SUL0 Q5SUL1 Q92891 Q92892 Q92893 Q92894 Q92895Q93053 Q96KU9 Q96KV0 Q96KV1 Q99605Alternative splicing: 10 isoforms: Q16653-1 Q16653-2 Q16653-3 Q16653-4 Q16653-5 Q16653-6 Q16653-7 Q16653-8 Q16653-9 Q16653-10 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)Explore the universe of human proteins at neXtProt for MOG: NX_Q16653
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16653
MOG Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (9 alternative transcripts):
NP_001008229.1 NP_001008230.1 NP_001163889.1 NP_002424.3 NP_996532.2 NP_996533.2 NP_996534.2 NP_996535.2 NP_996537.3
ENSEMBL proteins: ENSP00000366115 ENSP00000366101 ENSP00000366085 ENSP00000366091 ENSP00000418090 ENSP00000420350 ENSP00000409394 ENSP00000366088 ENSP00000366095 ENSP00000410866 ENSP00000379929 ENSP00000417405 ENSP00000379932 ENSP00000418872 ENSP00000366086 ENSP00000366100 ENSP00000431709
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
MOG for ontologies About GeneDecksing
MOG Antibody Products:
Assay Products for MOG: |
Protein
Domains /
Families
for MOG gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MOG for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16653ProtoNet protein and cluster: Q16653 1 Blocks protein family: IPB003596 Immunoglobulin V-type
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG familySimilarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain |
Function
for MOG gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653Function: Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involvedin completion and/or maintenance of the myelin sheath and in cell-cell communication Genatlas biochemistry entry for MOG:myelin oligodendrocyte glycoprotein,26-28kDa,associated with multiple sclerosis susceptibility
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOG (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOG (see all 11)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 9): MOG (NM_002433) | |  | Sino Biological Human cDNA Clone for MOG | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MOG | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOG |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOG |
1 GenomeRNAi human phenotype for MOG:
Animal Models:
Mouse knock-out Mogtm1Reid for MOG
8 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Mog):
MOG for phenotypes About GeneDecksing
|
Pathways & Interactions
for MOG gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MOG
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/7 Interacting proteins for MOG (Q166533 ENSP000003660954) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007155 | cell adhesion |
IEA | -- | | GO:0007417 | central nervous system development |
TAS | 1373175 | | GO:0034126 | positive regulation of MyD88-dependent toll-like receptor signaling pathway |
ISS | -- |
MOG for ontologies About GeneDecksing
|
Drugs & Compounds
for MOG gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MOG for compounds About GeneDecksing
 Compounds for MOG available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| MOG (35-55) | Encephalitogenic myelin oligodendrocyte glycoprotein fragment | [149635-73-4] |
10/15 Novoseek chemical compound relationships for MOG gene (see all 15) About this table
Search CenterWatch for drugs/clinical trials and news about MOG
|
Transcripts
for MOG gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MOG gene (10 alternative transcripts): NM_001008228.2 NM_001008229.2 NM_001170418.1 NM_002433.4 NM_206809.3 NM_206810.3 NM_206811.3 NM_206812.3 NM_206814.5 NM_206813.4 Unigene Cluster for MOG: Myelin oligodendrocyte glycoprotein Hs.141308 [show with all ESTs]Unigene Representative Sequence: NM_20680918/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000376917(uc003nna.3 uc011dlt.2 uc011dlv.2 uc011dlu.2 uc003nne.3 uc003nnf.3 uc003nng.3 uc003nni.3 uc003nnh.3 uc003nnj.3 uc003nnk.3)
ENST00000376903 ENST00000376888 ENST00000376894(uc003nmy.2) ENST00000469353
ENST00000483013 ENST00000490427 ENST00000416766 ENST00000376891 ENST00000376898
ENST00000431798 ENST00000396701 ENST00000494692 ENST00000396704 ENST00000476244
ENST00000469603 ENST00000485211 ENST00000376889
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOG (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOG (see all 11)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 9): MOG (NM_002433) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MOG | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOG |
Additional cDNA sequence: AB209815.1 AK295213.1 AK308949.1 AK312892.1 AY566846.1 AY566847.1 AY566848.1 AY566851.1 AY566852.1 AY566853.1 AY566854.1 U18798.1 U18799.1 U18800.2 U18801.1 U18803.1 U18840.1 U18843.1 U64564.1 U64565.1 U64566.1 U64567.1 U64568.1 U64569.1 U64570.1 U64571.1 X74511.1 17 DOTS entries: DT.100021881 DT.97776718 DT.100758942 DT.86852541 DT.95374215 DT.92423560 DT.451713 DT.101957614 DT.92423563 DT.121305358 DT.121305379 DT.95374216 DT.100758944 DT.100038778 DT.100890108 DT.95115608 DT.99947945 24/29 AceView cDNA sequences (see all 29): U18803 U64565 NM_206811 NM_002433 U64570 U64568 U18798 NM_206809 NM_206810 NM_206812 CR598447 BC035938 U18843 NM_206814 CR623648 U64569 U64571 U64566 U18840 U64567 NM_206813 X74511 U18801 U18799
GeneLoc Exon Structure
|
Expression
for MOG gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MOG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGCTTTAG
About this image
See MOG Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MOG
SOURCE GeneReport for Unigene cluster: Hs.141308
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653Tissue specificity: Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocytecytoplasmic membranes
SABiosciences Custom PCR Arrays for MOG
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MOG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOG | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOG |
Orthologs
for MOG gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MOG gene from 2/9 species (see all 9) About this table
ENSEMBL Gene Tree for MOG (if available)
TreeFam Gene Tree for MOG (if available) |
Paralogs
for MOG gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MOG gene
- BTN3A22 BTN2A12 BTNL82 ERMAP2 BTN3A32 BTN2A22 HHLA22 CD2762
- BTNL102 BTNL22 BTN3A12 VTCN12 BTN1A12 BTNL92 BTNL32
14 SIMAP similar genes for MOG using alignment to 27 protein entries: MOG_HUMAN (see all proteins):BTN1A1 BTNL8 SKINT1 BTN2A2 BTN3A1 BTN3A2
BTNL9 BTN3A3 BTN2A1 BTNL2 BTNL3 FAM221A
BTNL10 CD276
MOG for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MOG
PGOHUM00000244015
|
Genomic Variants
for MOG gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MOG (29624758 - 29640149 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MOG
1 CNV: 3598
Human Gene Mutation Database (HGMD): MOG
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MOG |
|
Disorders
/ Diseases
for MOG gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MOG for disorders About GeneDecksing
OMIM gene information: 159465
OMIM disorders: --
UniProtKB/Swiss-Prot: MOG_HUMAN, Q16653
Defects in MOG are the cause of narcolepsy type 7 (NRCLP7) [MIM:614250]. Neurological disabling sleepdisorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement(REM) sleep, cataplexy, hypnagogic hallucinations, and sleep paralysis. Cataplexy is a sudden loss of muscle tonetriggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy. Human narcolepsy isprimarily a sporadically occurring disorder but familial clustering has been observed
20/38  diseases for MOG (see all 38): About MalaCardssubacute sclerosing panencephalitis guillain-barre syndrome relapsing-remitting multiple sclerosis obsessive-compulsive disorder
hypersensitivity reaction type ii disease attention deficit hyperactivity disorder neuromyelitis optica optic neuritis
central nervous system disease multiple sclerosis temporal lobe epilepsy nervous system disease
acute disseminated encephalomyelitis pediatric multiple sclerosis neuritis viral encephalitis
encephalomyelitis allergic encephalomyelitis systemic lupus erythematosus adrenoleukodystrophy
5 diseases from the University of Copenhagen DISEASES database for MOG:Multiple sclerosis Optic neuritis Acute disseminated encephalomyelitis Hypersensitivity reaction type II disease
Neuromyelitis optica 10/30 Novoseek disease relationships for MOG gene (see all 30) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| multiple sclerosis |
88.7 |
104 |
12149493 (3), 7593547 (3), 9394837 (2), 10545390 (2) (see all 77) |
| encephalomyelitis |
86.1 |
32 |
11128602 (2), 1991822 (1), 8367453 (1), 12667650 (1) (see all 30) |
| demyelination |
84.4 |
50 |
11536329 (3), 1695240 (2), 15259003 (2), 11128602 (2) (see all 39) |
| demyelinating diseases |
77.4 |
14 |
8220243 (2), 20033986 (1), 12355425 (1), 17294606 (1) (see all 9) |
| autoimmune response |
66.7 |
15 |
9394837 (3), 8965116 (1), 11128602 (1), 11403222 (1) (see all 5) |
| multiple sclerosis relapsing-remitting |
58.2 |
1 |
17628700 (1) |
| autoimmune diseases |
58 |
4 |
11724443 (1), 20033986 (1), 9210466 (1), 11428934 (1) |
| neurological disorders |
54.2 |
14 |
9083925 (2), 8965116 (1), 9394837 (1), 12911279 (1) (see all 10) |
| optic neuritis |
53.1 |
2 |
12732654 (2) |
| mimicry |
49.3 |
6 |
11536329 (2), 14688379 (2), 14597104 (1), 14978022 (1) |
Genetic Association Database (GAD): MOG
Human Genome Epidemiology (HuGE) Navigator: MOG (27 documents)
Export disorders for MOG gene to outside databases
|
Publications
for MOG gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MOG gene, integrated from 9 sources (see all 259):
(articles sorted by number of sources associating them with MOG) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Myelin/oligodendrocyte glycoprotein is alternatively spliced in humans but not mice. (PubMed id 8915905)1, 2, 9 Ballenthin P.A. and Gardinier M.V. (1996)
- Genetic study of the myelin oligodendrocyte glycoprotein (MOG) gene in schizophrenia. (PubMed id 15660663)1, 4, 9 Zai G....Kennedy J.L. (2005)
- Myelin oligodendrocyte gene polymorphisms and childhood multiple sclerosis. (PubMed id 12149493)1, 4, 9 Ohlenbusch A....Hanefeld F. (2002)
- Characterization of cDNA and genomic clones encoding human myelin oligodendrocyte glycoprotein. (PubMed id 7790876)1, 2, 9 Hilton A.A.... Bernard C.C.A. (1995)
- Characterization and expression of the cDNA coding for the human myelin/oligodendrocyte glycoprotein. (PubMed id 7964757)1, 2, 9 Pham-Dinh D.... Dautigny A. (1994)
- Structure of the human myelin/oligodendrocyte glycoprotein gene and multiple alternative spliced isoforms. (PubMed id 8666381)1, 2, 9 Pham-Dinh D.... Dautigny A. (1995)
- The human myelin oligodendrocyte glycoprotein (MOG) gene: complete nucleotide sequence and structural characterization. (PubMed id 8530032)1, 2, 9 Roth M.-P.... Coppin H. (1995)
- A conformational study of the human and rat encephalitogenic myelin oligodendrocyte glycoprotein peptides 35-55. (PubMed id 9210466)1, 2, 9 Albouz-Abo S.... von Itzstein M. (1997)
- A missense mutation in myelin oligodendrocyte glycoprotein as a cause of familial narcolepsy with cataplexy. (PubMed id 21907016)1, 2 Hor H....Peraita-Adrados R. (2011)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
|
External Searches for MOG gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MOG gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MOG gene
(According to HUGE)
About This Section
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Specialized Databases showing MOG gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for MOG | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Myelin_oligodendrocyte_glycoprotein |
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About This Section
| Patent Information for MOG gene:
Search GeneIP for patents involving MOG
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MOG gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for MOG | | OriGene shRNA RFP for MOG | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MOG | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for MOG | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MOG | | OriGene 3'-UTR Clone for MOG | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOG | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOG | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MOG | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MOG | | OriGene Custom Protein Services for MOG | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MOG | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MOG | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOG | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MOG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOG |
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| | | | Tocris compounds for MOG |
| |  |  |  |  | | | | | | Recombinant Protein for MOG |
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 | | | MOG Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOG |
|  |  |  | | | | ThermoFisher Antibodies for MOG |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOG |
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