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MOBP Gene

protein-coding   GIFtS: 49
GCID: GC03P039508

Myelin-Associated Oligodendrocyte Basic Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Myelin-Associated Oligodendrocyte Basic Protein1 2

External Ids:    HGNC: 71891   Entrez Gene: 43362   Ensembl: ENSG000001683147   OMIM: 6009485   UniProtKB: Q138753   

Export aliases for MOBP gene to outside databases

Previous GC identifers: GC03U990052 GC03P038742 GC03P039322 GC03P039504 GC03P039469 GC03P039484


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MOBP Gene:
MOBP (myelin-associated oligodendrocyte basic protein) is a protein-coding gene. Diseases associated with MOBP include cocaine abuse, and substance abuse. GO annotations related to this gene include Rab GTPase binding and structural constituent of myelin sheath.

UniProtKB/Swiss-Prot: MOBP_HUMAN, Q13875
Function: May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively
charged acidic phospholipids of the cytoplasmic membrane (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the MOBP gene promoter:
         GR   TBP   GR-beta   POU2F1   POU2F1a   FOXO4   FOXO1a   GR-alpha   Zic3   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMOBP promoter sequence
   Search Chromatin IP Primers for MOBP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MOBP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.1   Ensembl cytogenetic band:  3p22.1   HGNC cytogenetic band: 3p21.33

MOBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MOBP gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P039508:  view genomic region     (about GC identifiers)

Start:
39,508,689 bp from pter      End:
39,570,970 bp from pter
Size:
62,282 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MOBP_HUMAN, Q13875 (See protein sequence)
Recommended Name: Myelin-associated oligodendrocyte basic protein  
Size: 183 amino acids; 20959 Da
Secondary accessions: A8K2C2 Q13874 Q6DHZ6 Q8TBJ1
Alternative splicing: 3 isoforms:  Q13875-1   Q13875-2   Q13875-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MOBP: NX_Q13875

Explore proteomics data for MOBP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MOBP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001265251.1  NP_001265252.1  NP_891980.1  

    ENSEMBL proteins: 
     ENSP00000410720   ENSP00000401312   ENSP00000400491   ENSP00000388148   ENSP00000409730  
     ENSP00000373261   ENSP00000409071   ENSP00000388827   ENSP00000312293   ENSP00000405549  
     ENSP00000389055   ENSP00000413771   ENSP00000379530   ENSP00000346695  

    MOBP Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for MOBP
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    Novus Biologicals MOBP Protein
    Novus Biologicals MOBP Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MOBP

    MOBP Antibody Products:

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    LSBio Antibodies in human, mouse, rat for MOBP

    MOBP Assay Products:

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    Cloud-Clone Corp. CLIAs for MOBP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR010911 Znf_FYVE-typ
     IPR026666 Mobp

    Graphical View of Domain Structure for InterPro Entry Q13875

    ProtoNet protein and cluster: Q13875


    MOBP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOBP_HUMAN, Q13875
    Function: May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively
    charged acidic phospholipids of the cytoplasmic membrane (By similarity)

         Genatlas biochemistry entry for MOBP:
    myelin-associated oligodendrocytic basic protein,with two isoforms

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017137Rab GTPase binding IEA--
    GO:0019911structural constituent of myelin sheath IEA--
         
    MOBP for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Mobp):
     behavior/neurological  nervous system 

    MOBP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for MOBP: Mobptm1Irg Mobptm1Sak

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MOBP
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MOBP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MOBP

    miRNA
    Products:
        
    miRTarBase miRNAs that target MOBP:
    hsa-mir-124-3p (MIRT022298), hsa-mir-1 (MIRT023529)

    Block miRNA regulation of human, mouse, rat MOBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MOBP (see all 13):
    hsa-miR-4291 hsa-miR-3934 hsa-miR-3688-3p hsa-miR-1288 hsa-miR-922 hsa-miR-520a-5p hsa-miR-1291 hsa-miR-455-3p
    SwitchGear 3'UTR luciferase reporter plasmidMOBP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MOBP
    Predesigned siRNA for gene silencing in human, mouse, rat MOBP

    Gene Editing
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    OriGene clones in human, mouse for MOBP (see all 7)
    OriGene ORF clones in mouse, rat for MOBP
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    GenScript: all cDNA clones in your preferred vector: MOBP (NM_182935)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MOBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOBP

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for MOBP
    Browse ESI BIO Cell Lines and PureStem Progenitors for MOBP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOBP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MOBP_HUMAN, Q13875: Cytoplasm, perinuclear region. Note=Present in the major dense line of CNS myelin (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol3
    extracellular2
    mitochondrion2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus ----
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--
    GO:0043231intracellular membrane-bounded organelle ----

    MOBP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MOBP
    Interactions:

        Search GeneGlobe Interaction Network for MOBP

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--
    GO:0007399nervous system development TAS7989345

    MOBP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MOBP

    2 Novoseek inferred chemical compound relationships for MOBP gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    2',3'-cyclic nucleotide 82.4 2 17510237 (1), 17964117 (1)
    cocaine 39.4 3 15849025 (1), 18357522 (1), 17291372 (1)



    MOBP for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MOBP gene (3 alternative transcripts): 
    NM_001278322.1  NM_001278323.1  NM_182935.3  

    Unigene Cluster for MOBP:

    Myelin-associated oligodendrocyte basic protein
    Hs.121333  [show with all ESTs]
    Unigene Representative Sequence: AK124766
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000451925 ENST00000428261 ENST00000420739 ENST00000415443 ENST00000447324
    ENST00000383754(uc003cju.3) ENST00000436143 ENST00000441980 ENST00000311042(uc003cjv.3 uc010hht.3)
    ENST00000452959(uc003cjw.3 uc003cjx.3 uc003cjy.3 uc003cjz.3)
    ENST00000424090 ENST00000442631 ENST00000479860 ENST00000396228 ENST00000354668

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MOBP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MOBP (see all 13):
    hsa-miR-4291 hsa-miR-3934 hsa-miR-3688-3p hsa-miR-1288 hsa-miR-922 hsa-miR-520a-5p hsa-miR-1291 hsa-miR-455-3p
    SwitchGear 3'UTR luciferase reporter plasmidMOBP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MOBP
    Predesigned siRNA for gene silencing in human, mouse, rat MOBP
    Clone
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    OriGene clones in human, mouse for MOBP (see all 7)
    OriGene ORF clones in mouse, rat for MOBP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MOBP (NM_182935)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MOBP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOBP
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MOBP
    OriGene qSTAR qPCR primer pairs in human, mouse for MOBP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MOBP
      QuantiTect SYBR Green Assays in human, mouse, rat MOBP
      QuantiFast Probe-based Assays in human, mouse, rat MOBP

    Additional mRNA sequence: 

    AK094745.1 AK124766.1 AK127034.1 AK290187.1 BC022471.1 BC075796.1 BC119694.1 BC119695.1 
    NR_003090.1 

    Selected DOTS entries (see all 25):

    DT.107411  DT.120921361  DT.91705049  DT.120921380  DT.120921391  DT.100776017  DT.120921532  DT.91692180 
    DT.97819503  DT.120921381  DT.120921333  DT.100661334  DT.40310649  DT.120921323  DT.75102667  DT.120921412 
    DT.95174802  DT.120921485  DT.120921520  DT.101983334  DT.120921355  DT.120921519  DT.40124703  DT.453858 

    Selected AceView cDNA sequences (see all 93):

    AA348428 AI569689 CF456481 AK095180 AI198080 BX951999 AA348427 AW873575 
    AI187940 AI243678 CR610306 AA774720 AI918199 AW594298 AV721963 BF511176 
    AI928659 BX951594 CF454837 AK127034 N59889 AK094745 AW445178 BC035141 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MOBP (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g
    SP1:                                      -     -           -           -                             -                                             
    SP2:                                            -           -                                                                                       
    SP3:                                            -           -     -     -     -     -     -     -     -                                             
    SP4:                                      -     -                                               -     -                                             
    SP5:                                      -     -           -                                         -                                             


    ECgene alternative splicing isoforms for MOBP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MOBP expression in normal human tissues (normalized intensities)      MOBP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MOBP Expression
    About this image


    MOBP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 22 entries
             Myelinating Oligodendrocyte Cells Forebrain White Matter
             Cerebral Cortex
             Oligodendrocyte-like cells
             Caudate nucleus   
     
     Spinal Cord (Nervous System)
             Oligodendrocyte-like cells
     
     Gonad
             Primordial Germ Cells Allantois
     
     Placenta (Extraembryonic Tissues)
             Primordial Germ Cells Allantois
     
     Oligodendrocytes (Nervous System)
             Oligodendrocyte-like cells
    MOBP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MOBP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.121333
        Custom PCR Arrays for MOBP
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    QuantiFast Probe-based Assays in human, mouse, rat MOBP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOBP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for MOBP gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mobp1 , 5 myelin-associated oligodendrocytic basic protein1, 5 83.83(n)1
    84.62(a)1
      9 (71.41 cM)5
    174331  NM_001039365.21  NP_001034454.11 
     1201497425 


    ENSEMBL Gene Tree for MOBP (if available)
    TreeFam Gene Tree for MOBP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MOBP gene
    1 SIMAP similar gene for MOBP using alignment to 4 protein entries:     MOBP_HUMAN (see all proteins):
    MYRIP

    MOBP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MOBP (see all 1398)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1844129301,2
    C--39507074(+) TCTATA/GTATGG 2 -- us2k10--------
    rs738264301,2
    C,F--39507207(+) TTGTAT/ATTTTT 2 -- us2k12Minor allele frequency- A:0.19WA 120
    rs1165477141,2
    F--39507278(+) ACCCAC/ACCCTG 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs17681581,2
    C,F,A,H--39507361(-) TTCACT/CGGTGG 2 -- us2k127Minor allele frequency- C:0.36NS EA NA WA CSA 2778
    rs17681491,2
    C,F,A--39507580(-) AGTTAA/GTTAAA 2 -- us2k1 tfbs311Minor allele frequency- G:0.41NA WA CSA EA 374
    rs1891673801,2
    --39507708(+) CATGGC/TGAAAC 2 -- us2k10--------
    rs1383844451,2
    --39507844(+) AGAGCA/GCCACT 2 -- us2k10--------
    rs1118251991,2
    C,F--39507876(+) AACCAG/CATTCC 2 -- us2k13Minor allele frequency- C:0.02NA WA 240
    rs17681261,2
    C,F--39507882(-) TGAGAC/TGGAAT 2 -- us2k14Minor allele frequency- T:0.28WA CSA EA 242
    rs1429622551,2
    C--39507937(+) AGTCAA/GTGTTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MOBP (39508689 - 39570970 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for MOBP:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2425951CNV Deletion19546169
    esv2725179CNV Deletion23290073
    esv1680226CNV Insertion17803354
    esv1395867CNV Insertion17803354
    nsv236980CNV Loss16902084
    nsv520957CNV Loss19592680
    dgv1450e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MOBP
    DNA2.0 Custom Variant and Variant Library Synthesis for MOBP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600948    OMIM disorders: --

    12 diseases for MOBP:    About MalaCards
    cocaine abuse    substance abuse    progressive supranuclear palsy    tauopathy
    major depressive disorder    mood disorder    multiple sclerosis    hypothyroidism
    schizophrenia    cerebritis    alzheimer's disease    neuronitis


    MOBP for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for MOBP gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cocaine abuse 71 1 17291372 (1)
    multiple sclerosis 46.4 3 10623862 (2), 19683076 (1)
    schizophrenia 44 4 16213148 (2), 17964117 (2)

    Genetic Association Database (GAD): MOBP
    Human Genome Epidemiology (HuGE) Navigator: MOBP (1 document)

    Export disorders for MOBP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MOBP gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with MOBP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and expression of myelin-associated oligodendrocytic basic protein. A novel basic protein constituting the central nervous system myelin. (PubMed id 7989345)1, 2, 3, 9 Yamamoto Y.... Sakoda S. (J. Biol. Chem. 1994)
    2. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. (PubMed id 21685912)1, 4 HAPglinger G.U....Schellenberg G.D. (Nat. Genet. 2011)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PubMed id 19734545)1, 4 Need A.C....Goldstein D.B. (Hum. Mol. Genet. 2009)
    5. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PubMed id 18839057)1, 4 Lesch K.P....Jacob C. (J Neural Transm 2008)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia. (PubMed id 17964117)1, 9 Mitkus S.N....Lipska B.K. (Schizophr. Res. 2008)
    9. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. (PubMed id 15009677)1, 9 Albertson D.N....Bannon M.J. (J. Neurochem. 2004)
    10. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)1 Sherva R....Green R.C. (amp 2014)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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    Free Text  

      Query String
    PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4336 HGNC: 7189 AceView: MOBP Ensembl:ENSG00000168314 euGenes: HUgn4336
    ECgene: MOBP H-InvDB: MOBP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MOBP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MOBP gene:
    Search GeneIP for patents involving MOBP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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