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Aliases for MOB3C Gene

Aliases for MOB3C Gene

  • MOB Kinase Activator 3C 2 3
  • Mob1 Homolog 2C 3 4
  • MOBKL2C 3 4
  • MOB1, Mps One Binder Kinase Activator-Like 2C (Yeast) 2
  • MOB1, Mps One Binder Kinase Activator-Like 2C 3
  • Mps One Binder Kinase Activator-Like 2C 4
  • MOB1E 3

External Ids for MOB3C Gene

Previous HGNC Symbols for MOB3C Gene


Previous GeneCards Identifiers for MOB3C Gene

  • GC01M046443
  • GC01M047075

Summaries for MOB3C Gene

Entrez Gene Summary for MOB3C Gene

  • The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

GeneCards Summary for MOB3C Gene

MOB3C (MOB Kinase Activator 3C) is a Protein Coding gene. An important paralog of this gene is MOB3A.

UniProtKB/Swiss-Prot for MOB3C Gene

  • May regulate the activity of kinases.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOB3C Gene

Genomics for MOB3C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MOB3C Gene

46,607,715 bp from pter
46,616,891 bp from pter
9,177 bases
Minus strand

Genomic View for MOB3C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOB3C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOB3C Gene

No data available for Regulatory Elements for MOB3C Gene

Proteins for MOB3C Gene

  • Protein details for MOB3C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    MOB kinase activator 3C
    Protein Accession:
    Secondary Accessions:
    • D3DQ22
    • Q0VA98
    • Q5TC10
    • Q5TC11
    • Q8NAZ2
    • Q8NF28

    Protein attributes for MOB3C Gene

    216 amino acids
    Molecular mass:
    25623 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC03434.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAC03752.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI14766.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for MOB3C Gene

Proteomics data for MOB3C Gene at MOPED

Post-translational modifications for MOB3C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MOB3C Gene

Antibody Products

No data available for DME Specific Peptides for MOB3C Gene

Domains for MOB3C Gene

Gene Families for MOB3C Gene

Protein Domains for MOB3C Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MOB1/phocein family.
  • Belongs to the MOB1/phocein family.
genes like me logo Genes that share domains with MOB3C: view

No data available for Suggested Antigen Peptide Sequences for MOB3C Gene

Function for MOB3C Gene

Molecular function for MOB3C Gene

UniProtKB/Swiss-Prot Function:
May regulate the activity of kinases.

Gene Ontology (GO) - Molecular Function for MOB3C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MOB3C: view

Animal Model Products

miRNA for MOB3C Gene

miRTarBase miRNAs that target MOB3C

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3C

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for MOB3C Gene

Localization for MOB3C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MOB3C Gene

Pathways for MOB3C Gene

SuperPathways for MOB3C Gene

No Data Available

Gene Ontology (GO) - Biological Process for MOB3C Gene


No data available for Pathways by source for MOB3C Gene

Transcripts for MOB3C Gene

Unigene Clusters for MOB3C Gene

MOB kinase activator 3C:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MOB3C Gene

No ASD Table

Relevant External Links for MOB3C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MOB3C Gene

mRNA expression in normal human tissues for MOB3C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for MOB3C Gene

This gene is overexpressed in Peripheral blood mononuclear cells (28.6), Liver, secretome (23.3), and Platelet (14.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MOB3C Gene

SOURCE GeneReport for Unigene cluster for MOB3C Gene Hs.632401

genes like me logo Genes that share expressions with MOB3C: view

Expression partners for MOB3C Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MOB3C Gene

Orthologs for MOB3C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MOB3C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MOB3C 35
  • 92.13 (n)
  • 98.61 (a)
MOB3C 36
  • 99 (a)
(Canis familiaris)
Mammalia MOB3C 35
  • 89.63 (n)
  • 92.12 (a)
MOB3C 36
  • 85 (a)
(Mus musculus)
Mammalia Mob3c 35
  • 90.12 (n)
  • 97.69 (a)
Mob3c 16
Mob3c 36
  • 98 (a)
(Pan troglodytes)
Mammalia MOBKL2C 35
  • 99.69 (n)
  • 100 (a)
MOB3C 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Mob3c 35
  • 89.37 (n)
  • 97.58 (a)
(Monodelphis domestica)
Mammalia MOB3C 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia MOB3C 36
  • 90 (a)
(Gallus gallus)
Aves MOBKL2C 35
  • 80.86 (n)
  • 84.26 (a)
MOB3C 36
  • 84 (a)
(Anolis carolinensis)
Reptilia MOB3C 36
  • 82 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mob3c 35
  • 72.84 (n)
  • 82.87 (a)
(Danio rerio)
Actinopterygii mob3c 35
  • 73.15 (n)
  • 80.56 (a)
mob3c 36
  • 81 (a)
fruit fly
(Drosophila melanogaster)
Insecta Mob3 36
  • 65 (a)
(Caenorhabditis elegans)
Secernentea T12B3.4 36
  • 48 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOB1 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2077 36
  • 66 (a)
Species with no ortholog for MOB3C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOB3C Gene

Gene Tree for MOB3C (if available)
Gene Tree for MOB3C (if available)

Paralogs for MOB3C Gene

Paralogs for MOB3C Gene

(7) SIMAP similar genes for MOB3C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MOB3C: view

Variants for MOB3C Gene

Sequence variations from dbSNP and Humsavar for MOB3C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs942083 -- 46,611,309(-) TAATA(C/G)TTATG intron-variant
rs1052301 -- 46,608,175(-) TGCTA(C/G)ATAGA utr-variant-3-prime
rs1258016 -- 46,618,034(-) TCCAC(C/T)CCCAA upstream-variant-2KB
rs1313388 -- 46,608,949(-) GGGAA(C/G)GTAGG utr-variant-3-prime
rs1767598 -- 46,614,635(+) TAGCC(C/T)TACCC intron-variant, utr-variant-5-prime

Relevant External Links for MOB3C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MOB3C Gene

Disorders for MOB3C Gene

No disorders were found for MOB3C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MOB3C Gene

Publications for MOB3C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Molecular characterization of human homologs of yeast MOB1. (PMID: 19739119) Chow A. … Yang X. (Int. J. Cancer 2010) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for MOB3C Gene

Sources for MOB3C Gene

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