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Aliases for MOB3B Gene

Aliases for MOB3B Gene

  • MOB Kinase Activator 3B 2 3
  • Mps One Binder Kinase Activator-Like 2B 3 4
  • Mob1 Homolog 2b 3 4
  • MOBKL2B 3 4
  • MOB1, Mps One Binder Kinase Activator-Like 2B (Yeast) 2
  • Monopolar Spindle 1 Binding, MOB1, Domain Containing 3
  • MOB1, Mps One Binder Kinase Activator-Like 2B 3
  • Chromosome 9 Open Reading Frame 35 2
  • Monopolar Spindle 1 Binding 2
  • Domain Containing 2
  • C9orf35 3
  • MOB1D 3
  • MOB1 2

External Ids for MOB3B Gene

Previous HGNC Symbols for MOB3B Gene

  • MOBKL2B
  • C9orf35

Summaries for MOB3B Gene

Entrez Gene Summary for MOB3B Gene

  • The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for MOB3B Gene

MOB3B (MOB Kinase Activator 3B) is a Protein Coding gene. An important paralog of this gene is MOB3A.

UniProtKB/Swiss-Prot for MOB3B Gene

  • May regulate the activity of kinases.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOB3B Gene

Genomics for MOB3B Gene

Genomic Location for MOB3B Gene

Start:
27,325,209 bp from pter
End:
27,529,852 bp from pter
Size:
204,644 bases
Orientation:
Minus strand

Genomic View for MOB3B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOB3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOB3B Gene

No data available for Regulatory Elements for MOB3B Gene

Proteins for MOB3B Gene

  • Protein details for MOB3B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86TA1-MOB3B_HUMAN
    Recommended name:
    MOB kinase activator 3B
    Protein Accession:
    Q86TA1
    Secondary Accessions:
    • Q8NEB4
    • Q9H8V4

    Protein attributes for MOB3B Gene

    Size:
    216 amino acids
    Molecular mass:
    25464 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MOB3B Gene

Proteomics data for MOB3B Gene at MOPED

Post-translational modifications for MOB3B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MOB3B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MOB3B Gene

Domains for MOB3B Gene

Gene Families for MOB3B Gene

HGNC:
  • MOB :MOB kinase activators

Protein Domains for MOB3B Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q86TA1

UniProtKB/Swiss-Prot:

MOB3B_HUMAN :
  • Q86TA1
Family:
  • Belongs to the MOB1/phocein family.
genes like me logo Genes that share domains with MOB3B: view

No data available for Suggested Antigen Peptide Sequences for MOB3B Gene

Function for MOB3B Gene

Molecular function for MOB3B Gene

UniProtKB/Swiss-Prot Function: May regulate the activity of kinases.

Gene Ontology (GO) - Molecular Function for MOB3B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MOB3B: view

miRNA for MOB3B Gene

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MOB3B Gene

Localization for MOB3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MOB3B Gene

Pathways for MOB3B Gene

SuperPathways for MOB3B Gene

No Data Available

Gene Ontology (GO) - Biological Process for MOB3B Gene

None

No data available for Pathways by source for MOB3B Gene

Compounds for MOB3B Gene

(1) PharmGKB related drug/compound annotations for MOB3B Gene

genes like me logo Genes that share compounds with MOB3B: view

Transcripts for MOB3B Gene

mRNA/cDNA for MOB3B Gene

(4) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MOB3B Gene

No ASD Table

Relevant External Links for MOB3B Gene

GeneLoc Exon Structure for
MOB3B
ECgene alternative splicing isoforms for
MOB3B

Expression for MOB3B Gene

mRNA expression in normal human tissues for MOB3B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MOB3B Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (4.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MOB3B Gene

SOURCE GeneReport for Unigene cluster for MOB3B Gene Hs.369022

genes like me logo Genes that share expressions with MOB3B: view

No data available for mRNA Expression by UniProt/SwissProt for MOB3B Gene

Orthologs for MOB3B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MOB3B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MOB3B 36
  • 100 (a)
OneToOne
MOBKL2B 35
  • 99.85 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia MOB3B 35
  • 92.28 (n)
  • 99.54 (a)
MOB3B 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MOB3B 35
  • 95.52 (n)
  • 99.07 (a)
MOB3B 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mob3b 35
  • 90.59 (n)
  • 98.15 (a)
Mob3b 16
Mob3b 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MOB3B 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MOB3B 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mob3b 35
  • 91.51 (n)
  • 98.61 (a)
chicken
(Gallus gallus)
Aves MOB3B 36
  • 94 (a)
OneToOne
MOBKL2B 35
  • 82.87 (n)
  • 93.98 (a)
lizard
(Anolis carolinensis)
Reptilia MOB3B 36
  • 96 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.14298 35
zebrafish
(Danio rerio)
Actinopterygii mob1bb 36
  • 53 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta Mob3 36
  • 66 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T12B3.4 36
  • 48 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOB1 36
  • 26 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.9757 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2077 36
  • 68 (a)
OneToMany
Species with no ortholog for MOB3B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MOB3B Gene

ENSEMBL:
Gene Tree for MOB3B (if available)
TreeFam:
Gene Tree for MOB3B (if available)

Paralogs for MOB3B Gene

Paralogs for MOB3B Gene

Selected SIMAP similar genes for MOB3B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MOB3B: view

Variants for MOB3B Gene

Sequence variations from dbSNP and Humsavar for MOB3B Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs3409 -- 27,326,090(+) CGATT(A/C)AAATA utr-variant-3-prime
rs3410 -- 27,326,062(+) ATTGA(A/G)TATGA utr-variant-3-prime
rs700793 -- 27,521,531(-) AAAAA(C/T)AGATA intron-variant
rs700794 -- 27,521,255(-) ATATT(A/G)TATTC intron-variant
rs700795 -- 27,520,510(-) ATGTA(C/T)CTCAA intron-variant

Relevant External Links for MOB3B Gene

HapMap Linkage Disequilibrium report
MOB3B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MOB3B Gene

Disorders for MOB3B Gene

No disorders were found for MOB3B Gene.

No data available for UniProtKB/Swiss-Prot for MOB3B Gene

Publications for MOB3B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for MOB3B Gene

Sources for MOB3B Gene

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