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Aliases for MOB3A Gene

Aliases for MOB3A Gene

  • MOB Kinase Activator 3A 2 3
  • Mps One Binder Kinase Activator-Like 2A 3 4
  • Mob1 Homolog 2A 3 4
  • MOB LAK 2 3
  • MOBKL2A 3 4
  • MOB-LAK 3 4
  • MOB1, Mps One Binder Kinase Activator-Like 2A (Yeast) 2
  • MOB1, Mps One Binder Kinase Activator-Like 2A 3
  • Moblak 3
  • MOB1C 3

External Ids for MOB3A Gene

Previous HGNC Symbols for MOB3A Gene

  • MOBKL2A

Summaries for MOB3A Gene

GeneCards Summary for MOB3A Gene

MOB3A (MOB Kinase Activator 3A) is a Protein Coding gene. An important paralog of this gene is MOB1A.

UniProtKB/Swiss-Prot for MOB3A Gene

  • May regulate the activity of kinases.

Gene Wiki entry for MOB3A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOB3A Gene

Genomics for MOB3A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MOB3A Gene

Start:
2,071,036 bp from pter
End:
2,096,673 bp from pter
Size:
25,638 bases
Orientation:
Minus strand

Genomic View for MOB3A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOB3A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOB3A Gene

No data available for Regulatory Elements for MOB3A Gene

Proteins for MOB3A Gene

  • Protein details for MOB3A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BX8-MOB3A_HUMAN
    Recommended name:
    MOB kinase activator 3A
    Protein Accession:
    Q96BX8
    Secondary Accessions:
    • B3KTF1
    • O75249
    • Q8TF69

    Protein attributes for MOB3A Gene

    Size:
    217 amino acids
    Molecular mass:
    25464 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC27672.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB84554.1; Type=Miscellaneous discrepancy; Note=Chimera. There is an inclusion of DNA from another gene in position 141.; Evidence={ECO:0000305};

neXtProt entry for MOB3A Gene

Proteomics data for MOB3A Gene at MOPED

Post-translational modifications for MOB3A Gene

  • Ubiquitination at Lys7
  • Modification sites at PhosphoSitePlus

Antibody Products

No data available for DME Specific Peptides for MOB3A Gene

Domains for MOB3A Gene

Gene Families for MOB3A Gene

HGNC:
  • MOB :MOB kinase activators

Protein Domains for MOB3A Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96BX8

UniProtKB/Swiss-Prot:

MOB3A_HUMAN :
  • Q96BX8
Family:
  • Belongs to the MOB1/phocein family.
genes like me logo Genes that share domains with MOB3A: view

No data available for Suggested Antigen Peptide Sequences for MOB3A Gene

Function for MOB3A Gene

Molecular function for MOB3A Gene

UniProtKB/Swiss-Prot Function: May regulate the activity of kinases.

Gene Ontology (GO) - Molecular Function for MOB3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MOB3A: view

Phenotypes for MOB3A Gene

GenomeRNAi human phenotypes for MOB3A:
genes like me logo Genes that share phenotypes with MOB3A: view

Animal Model Products

CRISPR Products

miRNA for MOB3A Gene

miRTarBase miRNAs that target MOB3A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3A

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MOB3A Gene

Localization for MOB3A Gene

Gene Ontology (GO) - Cellular Components for MOB3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with MOB3A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for MOB3A Gene

Pathways for MOB3A Gene

SuperPathways for MOB3A Gene

No Data Available

Interacting Proteins for MOB3A Gene

Gene Ontology (GO) - Biological Process for MOB3A Gene

None

No data available for Pathways by source for MOB3A Gene

Transcripts for MOB3A Gene

Unigene Clusters for MOB3A Gene

MOB kinase activator 3A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MOB3A Gene

No ASD Table

Relevant External Links for MOB3A Gene

GeneLoc Exon Structure for
MOB3A
ECgene alternative splicing isoforms for
MOB3A

Expression for MOB3A Gene

mRNA expression in normal human tissues for MOB3A Gene

mRNA differential expression in normal tissues according to GTEx for MOB3A Gene

This gene is overexpressed in Whole Blood (14.4).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for MOB3A Gene

SOURCE GeneReport for Unigene cluster for MOB3A Gene Hs.744938

genes like me logo Genes that share expressions with MOB3A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MOB3A Gene

Orthologs for MOB3A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MOB3A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MOB3A 35
  • 99.23 (n)
  • 100 (a)
MOB3A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MOB3A 35
  • 89.79 (n)
  • 93.78 (a)
MOB3A 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MOB3A 35
  • 92.17 (n)
  • 95.85 (a)
MOB3A 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mob3a 35
  • 85.41 (n)
  • 94.47 (a)
Mob3a 16
Mob3a 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MOB3A 36
  • 92 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MOB3A 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mob3a 35
  • 88.02 (n)
  • 94.93 (a)
chicken
(Gallus gallus)
Aves LOC100857182 35
  • 87.26 (n)
  • 91.04 (a)
MOB3A 36
  • 90 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mob3a 35
  • 75.15 (n)
  • 89.35 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3035 35
zebrafish
(Danio rerio)
Actinopterygii mob3a 35
  • 80.19 (n)
  • 84.91 (a)
mob3a 36
  • 85 (a)
OneToOne
wufc69e01 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007872 35
  • 65.41 (n)
  • 64.79 (a)
fruit fly
(Drosophila melanogaster)
Insecta Mob3 35
  • 63.38 (n)
  • 66.67 (a)
Mob3 36
  • 64 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T12B3.4 35
  • 60.81 (n)
  • 63.9 (a)
T12B3.4 36
  • 46 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOB1 36
  • 26 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2077 36
  • 69 (a)
OneToMany
Species with no ortholog for MOB3A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOB3A Gene

ENSEMBL:
Gene Tree for MOB3A (if available)
TreeFam:
Gene Tree for MOB3A (if available)

Paralogs for MOB3A Gene

Paralogs for MOB3A Gene

Selected SIMAP similar genes for MOB3A Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with MOB3A: view

Variants for MOB3A Gene

Sequence variations from dbSNP and Humsavar for MOB3A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs13597 -- 2,071,232(-) AAGAT(G/T)AAGCC utr-variant-3-prime
rs758144 -- 2,078,828(+) ATCAC(A/G)GCTCA intron-variant
rs758145 -- 2,073,467(+) ACTCC(C/T)AAAAG intron-variant
rs1000393 -- 2,075,667(+) CCGAG(A/T)CACAA intron-variant
rs1004320 -- 2,082,679(-) GCAGC(A/G)CTGGC intron-variant

Relevant External Links for MOB3A Gene

HapMap Linkage Disequilibrium report
MOB3A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MOB3A Gene

Disorders for MOB3A Gene

No disorders were found for MOB3A Gene.

No data available for UniProtKB/Swiss-Prot for MOB3A Gene

Publications for MOB3A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for MOB3A Gene

Sources for MOB3A Gene

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