Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MOB3A Gene

Aliases for MOB3A Gene

  • MOB Kinase Activator 3A 2 3
  • Mps One Binder Kinase Activator-Like 2A 3 4
  • Mob1 Homolog 2A 3 4
  • MOB LAK 2 3
  • MOBKL2A 3 4
  • MOB-LAK 3 4
  • MOB1, Mps One Binder Kinase Activator-Like 2A (Yeast) 2
  • MOB1, Mps One Binder Kinase Activator-Like 2A 3
  • Moblak 3
  • MOB1C 3

External Ids for MOB3A Gene

Previous HGNC Symbols for MOB3A Gene

  • MOBKL2A

Summaries for MOB3A Gene

GeneCards Summary for MOB3A Gene

MOB3A (MOB Kinase Activator 3A) is a Protein Coding gene. An important paralog of this gene is MOB1A.

UniProtKB/Swiss-Prot for MOB3A Gene

  • May regulate the activity of kinases.

Gene Wiki entry for MOB3A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOB3A Gene

Genomics for MOB3A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MOB3A Gene

Chromosome:
19
Start:
2,071,032 bp from pter
End:
2,096,673 bp from pter
Size:
25,642 bases
Orientation:
Minus strand

Genomic View for MOB3A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MOB3A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOB3A Gene

No data available for Regulatory Elements for MOB3A Gene

Proteins for MOB3A Gene

  • Protein details for MOB3A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BX8-MOB3A_HUMAN
    Recommended name:
    MOB kinase activator 3A
    Protein Accession:
    Q96BX8
    Secondary Accessions:
    • B3KTF1
    • O75249
    • Q8TF69

    Protein attributes for MOB3A Gene

    Size:
    217 amino acids
    Molecular mass:
    25464 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC27672.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB84554.1; Type=Miscellaneous discrepancy; Note=Chimera. There is an inclusion of DNA from another gene in position 141.; Evidence={ECO:0000305};

neXtProt entry for MOB3A Gene

Proteomics data for MOB3A Gene at MOPED

Post-translational modifications for MOB3A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MOB3A Gene

Domains & Families for MOB3A Gene

Gene Families for MOB3A Gene

Protein Domains for MOB3A Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for MOB3A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96BX8

UniProtKB/Swiss-Prot:

MOB3A_HUMAN :
  • Belongs to the MOB1/phocein family.
Family:
  • Belongs to the MOB1/phocein family.
genes like me logo Genes that share domains with MOB3A: view

Function for MOB3A Gene

Molecular function for MOB3A Gene

UniProtKB/Swiss-Prot Function:
May regulate the activity of kinases.

Gene Ontology (GO) - Molecular Function for MOB3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MOB3A: view
genes like me logo Genes that share phenotypes with MOB3A: view

Animal Model Products

miRNA for MOB3A Gene

miRTarBase miRNAs that target MOB3A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3A

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for MOB3A Gene

Localization for MOB3A Gene

Gene Ontology (GO) - Cellular Components for MOB3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with MOB3A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for MOB3A Gene

Pathways & Interactions for MOB3A Gene

SuperPathways for MOB3A Gene

No Data Available

Interacting Proteins for MOB3A Gene

Gene Ontology (GO) - Biological Process for MOB3A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MOB3A Gene

Drugs & Compounds for MOB3A Gene

No Compound Related Data Available

Transcripts for MOB3A Gene

Unigene Clusters for MOB3A Gene

MOB kinase activator 3A:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MOB3A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MOB3A Gene

No ASD Table

Relevant External Links for MOB3A Gene

GeneLoc Exon Structure for
MOB3A
ECgene alternative splicing isoforms for
MOB3A

Expression for MOB3A Gene

mRNA expression in normal human tissues for MOB3A Gene

mRNA differential expression in normal tissues according to GTEx for MOB3A Gene

This gene is overexpressed in Whole Blood (x14.4).

Protein differential expression in normal tissues from HIPED for MOB3A Gene

This gene is overexpressed in Tlymphocyte (13.2), Lymph node (8.6), and Bone (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for MOB3A Gene



SOURCE GeneReport for Unigene cluster for MOB3A Gene Hs.744938

genes like me logo Genes that share expression patterns with MOB3A: view

Protein tissue co-expression partners for MOB3A Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MOB3A Gene

Orthologs for MOB3A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MOB3A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MOB3A 35
  • 89.79 (n)
  • 93.78 (a)
MOB3A 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MOB3A 35
  • 92.17 (n)
  • 95.85 (a)
MOB3A 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mob3a 35
  • 85.41 (n)
  • 94.47 (a)
Mob3a 16
Mob3a 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MOB3A 35
  • 99.23 (n)
  • 100 (a)
MOB3A 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mob3a 35
  • 88.02 (n)
  • 94.93 (a)
oppossum
(Monodelphis domestica)
Mammalia MOB3A 36
  • 92 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MOB3A 36
  • 81 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC100857182 35
  • 87.26 (n)
  • 91.04 (a)
MOB3A 36
  • 90 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mob3a 35
  • 75.15 (n)
  • 89.35 (a)
zebrafish
(Danio rerio)
Actinopterygii mob3a 35
  • 80.19 (n)
  • 84.91 (a)
wufc69e01 35
mob3a 36
  • 85 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3035 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007872 35
  • 65.41 (n)
  • 64.79 (a)
fruit fly
(Drosophila melanogaster)
Insecta Mob3 35
  • 63.38 (n)
  • 66.67 (a)
Mob3 36
  • 64 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T12B3.4 35
  • 60.81 (n)
  • 63.9 (a)
T12B3.4 36
  • 46 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOB1 36
  • 26 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2077 36
  • 69 (a)
OneToMany
Species with no ortholog for MOB3A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MOB3A Gene

ENSEMBL:
Gene Tree for MOB3A (if available)
TreeFam:
Gene Tree for MOB3A (if available)

Paralogs for MOB3A Gene

Paralogs for MOB3A Gene

genes like me logo Genes that share paralogs with MOB3A: view

Variants for MOB3A Gene

Sequence variations from dbSNP and Humsavar for MOB3A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs13597 -- 2,071,232(-) AAGAT(G/T)AAGCC utr-variant-3-prime
rs758144 -- 2,078,828(+) ATCAC(A/G/T)GCTCA intron-variant
rs758145 -- 2,073,467(+) ACTCC(C/T)AAAAG intron-variant
rs1000393 -- 2,075,667(+) CCGAG(A/T)CACAA intron-variant
rs1004320 -- 2,082,679(-) GCAGC(A/G)CTGGC intron-variant

Variation tolerance for MOB3A Gene

Residual Variation Intolerance Score: 53.32% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.46; 28.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MOB3A Gene

HapMap Linkage Disequilibrium report
MOB3A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MOB3A Gene

Disorders for MOB3A Gene

Relevant External Links for MOB3A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MOB3A
genes like me logo Genes that share disorders with MOB3A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MOB3A Gene

Publications for MOB3A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. N-terminome analysis of the human mitochondrial proteome. (PMID: 25944712) Vaca Jacome A.S. … Carapito C. (Proteomics 2015) 67
  3. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67
  5. Molecular characterization of human homologs of yeast MOB1. (PMID: 19739119) Chow A. … Yang X. (Int. J. Cancer 2010) 67

Products for MOB3A Gene

Sources for MOB3A Gene

Back to Top

Content