Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MOB2 Gene

protein-coding   GIFtS: 46
GCID: GC11M001490

MOB Kinase Activator 2

  Search for MOB2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
MOB Kinase Activator 21 2
HCCA22 3 5
Mob2 Homolog2 3
Mps One Binder Kinase Activator-Like 22 3
MOB2 Mps One Binder Homolog (Yeast)1
MOB2 Mps One Binder Homolog2

External Ids:    HGNC: 249041   Entrez Gene: 815322   Ensembl: ENSG000001822087   OMIM: 6119695   UniProtKB: Q70IA63   

Export aliases for MOB2 gene to outside databases

Previous GC identifer: GC11M001278


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MOB2 Gene: 
MOB2 (MOB kinase activator 2) is a protein-coding gene. GO annotations related to this gene include metal ion binding. An important paralog of this gene is MOB3C.

UniProtKB/Swiss-Prot: MOB2_HUMAN, Q70IA6
Function: Stimulates the autophosphorylation and kinase activity of STK38 and STK38L




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_009237.18  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for MOB2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMOB2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MOB2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

MOB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MOB2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M001490:  view genomic region     (about GC identifiers)

Start:
1,490,685 bp from pter      End:
1,522,477 bp from pter
Size:
31,793 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MOB2_HUMAN, Q70IA6 (See protein sequence)
Recommended Name: MOB kinase activator 2  
Size: 237 amino acids; 26927 Da
Subunit: Binds STK38 and STK38L
Subcellular location: Nucleus. Cytoplasm, perinuclear region
Secondary accessions: B4DKP3 Q96M67
Alternative splicing: 3 isoforms:  Q70IA6-1   Q70IA6-2   Q70IA6-3   (Ref.2 (BAG59255) sequence is in conflict in position: 19:L->P)

Explore the universe of human proteins at neXtProt for MOB2: NX_Q70IA6

Explore proteomics data for MOB2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q70IA6

  • MOB2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MOB2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001165694.1  NP_443731.2  

    ENSEMBL proteins: 
     ENSP00000328694  

    Human Recombinant Protein Products for MOB2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for MOB2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MOB2
    GenScript Custom Purified and Recombinant Proteins Services for MOB2
    Novus Biologicals MOB2 Protein
    Novus Biologicals MOB2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0048471perinuclear region of cytoplasm IEA--

    MOB2 for ontologies           About GeneDecksing



    MOB2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MOB2
    GenScript Custom Superior Antibodies Services for MOB2
    Novus Biologicals MOB2 Antibodies
    Abcam antibodies for MOB2
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibody for MOB2
    LSBio Antibodies in human, mouse, rat for MOB2 

    Assay Products for MOB2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MOB2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MOB2
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MOB: MOB kinase activators

    1 InterPro protein domain:
     IPR005301 Mob1_phocein

    Graphical View of Domain Structure for InterPro Entry Q70IA6

    ProtoNet protein and cluster: Q70IA6

    1 Blocks protein domain: IPB005301 Mob1/phocein family

    UniProtKB/Swiss-Prot: MOB2_HUMAN, Q70IA6
    Similarity: Belongs to the MOB1/phocein family


    MOB2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOB2_HUMAN, Q70IA6
    Function: Stimulates the autophosphorylation and kinase activity of STK38 and STK38L

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    MOB2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MOB2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MOB2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MOB2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MOB2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MOB2
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MOB2:
    hsa-miR-4324 hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidMOB2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MOB2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MOB2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MOB2
    Sirion Biotech Customized adenovirus for overexpression of MOB2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MOB2 (see all 12)
    OriGene ORF clones in mouse, rat for MOB2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MOB2 (NM_053005)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MOB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB2
    Sirion Biotech Customized lentivirus for stable overexpression of MOB2 
                         Customized lentivirus expression plasmids for stable overexpression of MOB2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MOB2
    Search LifeMap BioReagents cell lines for MOB2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MOB2

    2 Interacting proteins for MOB2 (Q70IA63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDRG2Q9UN363I2D: score=1 
    STK38Q152083I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MOB2

    Search CenterWatch for drugs/clinical trials and news about MOB2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MOB2 gene (2 alternative transcripts): 
    NM_001172223.1  NM_053005.4  

    Unigene Cluster for MOB2:

    MOB kinase activator 2
    Hs.370360  [show with all ESTs]
    Unigene Representative Sequence: BX537373
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000531976(uc001lto.2 uc001ltp.1 uc001ltq.2) ENST00000329957(uc010qwz.2)
    ENST00000526462 ENST00000526698 ENST00000529380 ENST00000529897
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MOB2
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MOB2:
    hsa-miR-4324 hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidMOB2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MOB2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MOB2
    Clone
    Products:
         
    OriGene clones in human, mouse for MOB2 (see all 12)
    OriGene ORF clones in mouse, rat for MOB2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MOB2 (NM_053005)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MOB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB2
    Sirion Biotech Customized lentivirus for stable overexpression of MOB2 
                         Customized lentivirus expression plasmids for stable overexpression of MOB2 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MOB2
    OriGene qSTAR qPCR primer pairs in human, mouse for MOB2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MOB2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOB2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOB2

    Additional mRNA sequence: 

    AB066564.1 AJ580639.1 AK057350.1 AK296658.1 AK300235.1 BC035317.1 BC047291.1 BC058934.1 
    BC067785.1 BX537373.1 

    8 DOTS entries:

    DT.113456  DT.40192510  DT.97844783  DT.95134020  DT.95134015  DT.75102016  DT.100028270  DT.95134018 

    24/181 AceView cDNA sequences (see all 181):

    CR623644 CA946949 AA358209 AI673640 BM015956 CR591411 CR592866 CD108611 
    CD365072 BG055686 BQ694944 BM993205 AI380671 BM663806 BQ230053 AA670391 
    BU737994 CR607171 BQ883981 BI458068 BE906058 CA446283 BM480305 T30370 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MOB2 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e
    SP1:              -           -                                             
    SP2:        -     -           -                                             
    SP3:        -     -           -                                             
    SP4:              -           -                                             
    SP5:              -           -                                             


    ECgene alternative splicing isoforms for MOB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MOB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGCAGTCCT
    MOB2 Expression
    About this image


    See MOB2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MOB2

    SOURCE GeneReport for Unigene cluster: Hs.370360
        SABiosciences Custom PCR Arrays for MOB2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MOB2
    OriGene qSTAR qPCR primer pairs in human, mouse for MOB2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MOB2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOB2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOB2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MOB2 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mob21 , 5 MOB kinase activator 21, 5 86.93(n)1
    91.38(a)1
      7 (87.50 cM)5
    1015131  NM_028308.21  NP_082584.11 
     1420085535 
    chicken
    (Gallus gallus)
    Aves MOB21 MOB kinase activator 2 78.57(n)
    82.71(a)
      423097  XM_421030.3  XP_421030.1 
    lizard
    (Anolis carolinensis)
    Reptilia MOB26
    MOB kinase activator 2
    78(a)
    1 ↔ 1
    1(71126131-71259959)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC760422 hypothetical protein MGC76042 87.98(n)    BC061432.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mob2b1 MOB kinase activator 2b 77.34(n)
    77.34(a)
      724012  NM_001045317.1  NP_001038782.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mob26
    Mob2
    16(a)
    1 ↔ 1
    3L(11515857-11555333)
    worm
    (Caenorhabditis elegans)
    Secernentea F38H4.106
    F09A5.46
    Protein F09A5.4, isoform c
    33(a)
    19(a)
    possible ortholog
    1 ↔ 1
    IV(11860555-11862499)
    X(13152835-13170075)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MOB16
    Component of the mitotic exit network; associates ...
    23(a)
    1 → many
    IX(166415-167444)


    ENSEMBL Gene Tree for MOB2 (if available)
    TreeFam Gene Tree for MOB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MOB2 gene
    MOB3C2  MOB3B2  MOB3A2  MOB1B2  MOB1A2  
    7 SIMAP similar genes for MOB2 using alignment to 1 protein entry:     MOB2_HUMAN:
    MOB1B    MOB4A    MOBKL1A    MOB1A    MOB3A    MOB3B
    MOB3C

    MOB2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1479 SNPs in MOB2 are shown (see all 1479)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs127865041,2
    C,F--1278201(+) TTCCCG/ACTTCT 1 -- int110Minor allele frequency- A:0.20NA CSA WA EA 492
    rs1911998641,2
    --1278249(+) TTAGGA/GCCCCT 1 -- int10--------
    rs592329731,2
    --1278255(+) CCCCTC/GTCCCT 1 -- int10--------
    rs71296621,2
    C,F--1278384(+) CCTTCG/AGAGAA 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1825679481,2
    --1278440(+) AGCACC/GGGGAG 1 -- int10--------
    rs1876945541,2
    --1278488(+) ACAGGA/GTATGT 1 -- int10--------
    rs1923681751,2
    --1278505(+) CCCACA/GGCACC 1 -- int10--------
    rs1458477691,2
    --1278662(+) CGAGAC/TGCTGA 1 -- int10--------
    rs1387595341,2
    --1278716(+) GTGAAA/CAGATG 1 -- ut310--------
    rs1831446601,2
    --1279037(+) CTCCCC/GCCACG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MOB2 (1490685 - 1522477 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/93 variations for MOB2 (see all 93):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2743948CNV Deletion23290073
    esv2743944CNV Deletion23290073
    esv2743954CNV Deletion23290073
    esv2743949CNV Deletion23290073
    esv2743955CNV Deletion23290073
    esv2403037CNV Deletion18987734
    esv2743938CNV Deletion23290073
    esv2665572CNV Deletion23128226
    esv2743941CNV Deletion23290073
    dgv185e199CNV Deletion23128226

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MOB2
    DNA2.0 Custom Variant and Variant Library Synthesis for MOB2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MOB2 for disorders           About MalaCards
    OMIM gene information: 611969    OMIM disorders: --


    MOB2 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: MOB2 (2 documents)

    Export disorders for MOB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MOB2 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with MOB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. (PubMed id 15067004)1, 2, 3, 9 Devroe E.... Silver P.A. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Gene expression profile in Alzheimer's brain screened by molecular indexing. (PubMed id 11223154)1, 3 Doyu M.... Kato K. (2001)
    5. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. (PubMed id 23084401)1 Singh G....Moore M.J. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    8. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    9. Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR ki nases. (PubMed id 20624913)1 Kohler R.S....Hergovich A. (2010)
    10. Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide pol ymorphisms. (PubMed id 20889853)1 de Miguel-Yanes J.M....Meigs J.B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81532 HGNC: 24904 AceView: HCCA2 Ensembl:ENSG00000182208 euGenes: HUgn81532
    ECgene: MOB2 H-InvDB: MOB2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MOB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MOB2 gene:
    Search GeneIP for patents involving MOB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MOB2  
     OriGene qPCR primer pairs and template standards for MOB2   OriGene Protein Over-expression Lysate for MOB2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MOB2  
     OriGene qSTAR qPCR primer pairs in human, mouse for MOB2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for MOB2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MOB2   OriGene Custom Protein Services for MOB2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MOB2
     QIAGEN SeqTarget long-range PCR primers for resequencing MOB2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOB2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MOB2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOB2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOB2
     GenScript Custom Purified and Recombinant Proteins Services for MOB2 GenScript cDNA clones with any tag delivered in your preferred vector for MOB2
     GenScript Custom Assay Services for MOB2 GenScript Custom Superior Antibodies Services for MOB2
     GenScript Custom overexpressing Cell Line Services for MOB2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for MOB2
     Search Chromatin IP Primers for MOB2
     RT2 qPCR Primer Assay in human, mouse, rat MOB2
     Search GNC Networks for MOB2
     SABiosciences Custom PCR Arrays for MOB2
     Search Tocris compounds for MOB2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MOB2 antibodies
     MOB2 proteins
     MOB2 lysates
     Antibodies for MOB2
     See all of Abcam's Antibodies, Kits and Proteins for MOB2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for MOB2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB2
     SwitchGear 3'UTR luciferase reporter plasmids for MOB2
     SwitchGear Promoter luciferase reporter plasmids for MOB2
     ThermoFisher Antibody for MOB2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for MOB2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MOB2
    Customized:
     lentivirus for stable overexpression of MOB2
     lentivirus expression plasmids for stable overexpression of MOB2
     adenovirus for overexpression of MOB2
     LSBio Antibodies in human, mouse, rat for MOB2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MOB2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4