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MOB1B Gene

protein-coding   GIFtS: 49
GCID: GC04P071769

MOB Kinase Activator 1B

(Previous names: MOB1, Mps One Binder kinase activator-like 1A (yeast), MOB1...)
(Previous symbol: MOBKL1A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MOB Kinase Activator 1B1 2     Mob4A Protein1
MOBKL1A1 2 3     MATS22
Mob1 Homolog 1A2 3     MOB1 Mps One Binder Homolog B2
Mps One Binder Kinase Activator-Like 1A2 3     MOB1, Mps One Binder Kinase Activator-Like 1A2
MOB4A2 3     mob1A2
MOB1 Mps One Binder Homolog B (Yeast)1     Mob1A3
MOB1, Mps One Binder Kinase Activator-Like 1A (Yeast)1     Mob1B3

External Ids:    HGNC: 298011   Entrez Gene: 925972   Ensembl: ENSG000001735427   OMIM: 6092825   UniProtKB: Q7L9L43   

Export aliases for MOB1B gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MOB1B Gene:
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase
essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Sep 2011)

GeneCards Summary for MOB1B Gene:
MOB1B (MOB kinase activator 1B) is a protein-coding gene. Diseases associated with MOB1B include thyroiditis, and prostatitis. GO annotations related to this gene include kinase binding and kinase activator activity. An important paralog of this gene is MOB3C.

UniProtKB/Swiss-Prot: MOB1B_HUMAN, Q7L9L4
Function: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and
tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a
kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and
activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1
oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to
regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase
activity of STK38L

Gene Wiki entry for MOB1B (MOBKL1A) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for MOB1B
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMOB1B promoter sequence
   Search Chromatin IP Primers for MOB1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MOB1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

MOB1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MOB1B gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P071769:  view genomic region     (about GC identifiers)

Start:
71,768,043 bp from pter      End:
71,888,166 bp from pter
Size:
120,124 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MOB1B_HUMAN, Q7L9L4 (See protein sequence)
Recommended Name: MOB kinase activator 1B  
Size: 216 amino acids; 25091 Da
Subunit: Binds STK38L. Interacts with LATS1 and LATS2
Secondary accessions: B2R8U6 B4DRY3 Q8IY23
Alternative splicing: 2 isoforms:  Q7L9L4-1   Q7L9L4-2   

Explore the universe of human proteins at neXtProt for MOB1B: NX_Q7L9L4

Explore proteomics data for MOB1B at MOPED

Post-translational modifications: 

  • Phosphorylated by STK3/MST2 and STK4/MST1 and this phosphorylation enhances its binding to LATS11
  • Ubiquitination2 at Lys17, Lys30, Lys104, Lys142
  • Modification sites at PhosphoSitePlus

  • See MOB1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001231695.1  NP_001231696.1  NP_775739.1  

    ENSEMBL proteins: 
     ENSP00000427216   ENSP00000310189   ENSP00000379366  
    Reactome Protein details: Q7L9L4

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MOB: MOB kinase activators

    1 InterPro protein domain:
     IPR005301 Mob1_phocein

    Graphical View of Domain Structure for InterPro Entry Q7L9L4

    ProtoNet protein and cluster: Q7L9L4

    1 Blocks protein domain: IPB005301 Mob1/phocein family

    UniProtKB/Swiss-Prot: MOB1B_HUMAN, Q7L9L4
    Similarity: Belongs to the MOB1/phocein family


    MOB1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOB1B_HUMAN, Q7L9L4
    Function: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and
    tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a
    kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and
    activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1
    oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to
    regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase
    activity of STK38L

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19739119
    GO:0019209kinase activator activity IDA15197186
    GO:0019900kinase binding IPI15197186
    GO:0046872metal ion binding IEA--
         
    MOB1B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MOB1B:
     Decreased number of cells in m 

         14 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mob1b):
     behavior/neurological  cellular  craniofacial  digestive/alimentary  embryogenesis 
     growth/size/body  hearing/vestibular/ear  integument  limbs/digits/tail  mortality/aging 
     nervous system  normal  skeleton  tumorigenesis 

    MOB1B for phenotypes           About GeneDecksing

    Animal Models:
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    miRTarBase miRNAs that target MOB1B:
    hsa-mir-17-5p (MIRT050791), hsa-mir-128-3p (MIRT022073), hsa-mir-181a-5p (MIRT025196), hsa-let-7b-5p (MIRT032390)

    Block miRNA regulation of human, mouse, rat MOB1B using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MOB1B_HUMAN, Q7L9L4: Cytoplasm. Nucleus

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15067004
    GO:0005737cytoplasm IDA15067004
    GO:0005829cytosol TAS--
    GO:0070062extracellular vesicular exosome IDA--

    MOB1B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MOB1B About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling by GPCR
    Signal Transduction0.58
    2Wnt / Hedgehog / Notch
    Wnt / Hedgehog / Notch
    3Signaling by Hippo
    Signaling by Hippo
    4Hippo signaling pathway
    Hippo signaling pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for MOB1B
        Wnt / Hedgehog / Notch


    1 Reactome Pathway for MOB1B
        Signaling by Hippo


    1 Kegg Pathway  (Kegg details for MOB1B):
        Hippo signaling pathway


    MOB1B for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MOB1B
    Interactions:

        Search GeneGlobe Interaction Network for MOB1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MOB1B (Q7L9L41, 2, 3 ENSP000003101894) via UniProtKB, MINT, STRING, and/or I2D (see all 86)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MST1P269272, 3MINT-4787512 I2D: score=1 
    LATS1O958351, 3, ENSP000002533394EBI-2558745,EBI-444209 I2D: score=1 STRING: ENSP00000253339
    LATS2Q9NRM71, 3, ENSP000003720354EBI-2558745,EBI-3506895 I2D: score=1 STRING: ENSP00000372035
    STK38LQ9Y2H13I2D: score=5 
    PTPN11Q061243I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035329hippo signaling TAS--
    GO:0042327positive regulation of phosphorylation IDA15197186
    GO:0046777protein autophosphorylation IDA15197186

    MOB1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MOB1B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MOB1B gene (3 alternative transcripts): 
    NM_001244766.1  NM_001244767.1  NM_173468.3  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000502869 ENST00000309395(uc011cba.2 uc003hfw.3) ENST00000509041(uc003hfv.2)
    ENST00000396051 ENST00000511449
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat MOB1B
      QuantiFast Probe-based Assays in human, mouse, rat MOB1B

    Selected AceView cDNA sequences (see all 124):

    BQ229138 AA862533 BX643132 BM699377 CA441486 BX089615 BF477381 AJ577473 
    AW316585 AK093545 CA407941 AA883510 NM_173468 AW779302 AA043917 AA811686 
    AX748194 CD677669 CA395464 AI096772 AA994125 BF439833 AI421204 CA443020 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MOB1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGACAGTTT
    MOB1B Expression
    About this image

    MOB1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MOB1B Protein Expression

    UniProtKB/Swiss-Prot: MOB1B_HUMAN, Q7L9L4
    Tissue specificity: Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle,
    testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MOB1B gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mob1b1 , 5 MOB kinase activator 1B1, 5 91.63(n)1
    100(a)1
      5 (43.92 cM)5
    684731  NM_026735.21  NP_081011.11 
     887208555 
    chicken
    (Gallus gallus)
    Aves MOBKL1A1 MOB1, Mps One Binder kinase activator-like 1A (yeast) 87.2(n)
    100(a)
      422647  XM_420601.4  XP_420601.2 
    lizard
    (Anolis carolinensis)
    Reptilia MOB1B6
    MOB kinase activator 1B
    98(a)
    1 ↔ 1
    5(147182825-147212810)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mob1b1 MOB kinase activator 1B 81.52(n)
    98.1(a)
      780027  NM_001079104.1  NP_001072572.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC063989.12   -- 80.42(n)   393169  BC063989.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mats1 mob as tumor suppressor 70.79(n)
    88.57(a)
      42634  NM_001275906.1  NP_001262835.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MOB16
    Component of the mitotic exit network; associates ...
    34(a)
    1 → many
    IX(166415-167444) YIL106W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G455501 AT5G45550 64.9(n)
    68.6(a)
      834591  NM_123923.5  NP_199368.1 
    rice
    (Oryza sativa)
    Liliopsida AK098953.12   -- 74.44(n)    AK098953.1 


    ENSEMBL Gene Tree for MOB1B (if available)
    TreeFam Gene Tree for MOB1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MOB1B gene
    MOB3C2  MOB3B2  MOB22  MOB3A2  MOB1A2  
    8 SIMAP similar genes for MOB1B using alignment to 2 protein entries:     MOB1B_HUMAN (see all proteins):
    MOB4A    MOBKL1A    MOB1A    DKFZp686N2312    MOB3A    MOB3B
    MOB3C    MOB2

    MOB1B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MOB1B (see all 1621)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs343035151,2
    C--67572842(+) TTTTT-/TTTTTTTTT
    /TTTTTTTTTT
    ACCAC
    6 -- us2k1 cds11NA 2
    rs1148242521,2
    F--71766059(+) GTAATG/AATAGA 3 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1160223181,2
    C,F--71766195(+) CTGGGA/C/TGTGGT 3 -- us2k11WA 118
    rs287031731,2
    C,F--71766241(+) AAGGCG/AGGCAG 3 -- us2k12Minor allele frequency- A:0.33WA CSA 3
    rs1133170281,2
    C--71766256(+) CGAGGT/ACAGGA 3 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1432967081,2
    --71766436(+) CACTGC/GACTCC 3 -- us2k10--------
    rs100201321,2
    C,F--71766450(+) ctgggC/Tgacag 3 -- us2k12Minor allele frequency- T:0.33WA CSA 3
    rs1899567571,2
    --71766504(+) ACAGTA/CAGTCA 3 -- us2k10--------
    rs104465071,2
    C,F,A,H--71766612(+) AAAAAT/Attttt 3 -- us2k19Minor allele frequency- A:0.33NS NA WA EA 606
    rs1408363671,2
    --71766622(+) TAATTG/TAATTT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for MOB1B (71768043 - 71888166 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MOB1B: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MOB1B
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609282    OMIM disorders: --

    3 diseases for MOB1B:    
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    thyroiditis    prostatitis    malaria


    MOB1B for disorders           About GeneDecksing


    Export disorders for MOB1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MOB1B gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with MOB1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. (PubMed id 15067004)1, 2, 3 Devroe E.... Silver P.A. (J. Biol. Chem. 2004)
    2. Molecular characterization of human homologs of yeast MOB1. (PubMed id 19739119)1, 2 Chow A.... Yang X. (Int. J. Cancer 2010)
    3. MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. (PubMed id 18328708)1, 2 Praskova M.... Avruch J. (Curr. Biol. 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Viral immune modulators perturb the human molecular network by common and unique strategies. (PubMed id 22810585)1 Pichlmair A....Superti-Furga G. (Nature 2012)
    10. Human Mob1 proteins are required for cytokinesis by controlling microtubule stability. (PubMed id 22454515)1 Florindo C....Tavares A.A. (J. Cell. Sci. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 92597 HGNC: 29801 AceView: MOBKL1A Ensembl:ENSG00000173542 euGenes: HUgn92597
    ECgene: MOB1B Kegg: 92597 H-InvDB: MOB1B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MOB1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MOB1B gene:
    Search GeneIP for patents involving MOB1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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