MOB1A Gene
protein-coding GIFtS: 52
GCID: GC02M074382
|
|
MOB kinase activator 1A(Previous names: chromosome 2 open reading frame 6, MOB1, Mps One Binder...)
(Previous symbols: C2orf6, MOBK1B, MOBKL1B)
| |
Aliases
for MOB1A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MOB Kinase Activator 1A1 2 | | FLJ115951 | | C2orf61 2 3 | | Mats11 | | MOBK1B1 2 3 | | Chromosome 2 Open Reading Frame 61 | | MOBKL1B1 2 3 | | MOB1 Mps One Binder Homolog A (Yeast)1 | | MOB11 2 | | MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast)1 | | Mob4B1 2 | | MATS12 | | Mob1 Alpha2 3 | | MOB1 Mps One Binder Homolog A2 | | Mob1 Homolog 1B2 3 | | MOB1, Mps One Binder Kinase Activator-Like 1B2 | | Mps One Binder Kinase Activator-Like 1B2 3 | | MOB4B3 | | FLJ107881 | | Mob1A3 |
Export aliases for MOB1A gene to outside databases |
Summaries
for MOB1A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MOB1A_HUMAN, Q9H8S9Function: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control andtumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of akinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates andactivates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulatecellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity ofSTK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38
Gene Wiki entry for MOB1A (MOBKL1B)
|
Genomic Views
for MOB1A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MOB1A
Other transcription factors
Search SABiosciences Chromatin IP Primers for MOB1A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOB1A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13.1 Ensembl cytogenetic band: 2p13.1 HGNC cytogenetic band: 2p13.1MOB1A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M074382: view genomic region
(about GC identifiers)
Start:
|
74,382,165 bp from pter |
End:
|
74,406,025 bp from pter |
Size:
|
23,861 bases |
Orientation:
|
minus strand |
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Proteins
for MOB1A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MOB1A_HUMAN, Q9H8S9 (See
protein sequence)Recommended Name: MOB kinase activator 1A Size: 216 amino acids; 25080 Da
Subunit: Binds STK38 and STK38L. Interacts with LATS1 and LATS2. Forms a tripartite complex with STK38 and STK3/MST2
1 PDB 3D structure from  and Proteopedia  for MOB1A:1PI1 (3D)
Secondary accessions: Q53S34 Q9H3T5 Q9HAI0 Q9NVE2Alternative splicing: 2 isoforms: Q9H8S9-1 Q9H8S9-2 (May be due to an intron retention)Explore the universe of human proteins at neXtProt for MOB1A: NX_Q9H8S9
Post-translational modifications:
Phosphorylated by STK3/MST2 and STK4/MST1 and this phosphorylation enhances its binding to LATS11
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H8S9
MOB1A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060691.2
ENSEMBL proteins: ENSP00000379364 ENSP00000386782 Reactome Protein details: Q9H8S9
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- |
MOB1A for ontologies About GeneDecksing
MOB1A Antibody Products:
Assay Products for MOB1A: |
Protein
Domains /
Families
for MOB1A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MOB1A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H8S9ProtoNet protein and cluster: Q9H8S9 1 Blocks protein family: IPB005301 Mob1/phocein family
UniProtKB/Swiss-Prot: MOB1A_HUMAN, Q9H8S9Similarity: Belongs to the MOB1/phocein family |
Function
for MOB1A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MOB1A_HUMAN, Q9H8S9Function: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control andtumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of akinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates andactivates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulatecellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity ofSTK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MOB1A | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MOB1A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB1A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB1A |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
MOB1A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MOB1A:
|
Pathways & Interactions
for MOB1A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by Hippo | | | 2 | Wnt / Hedgehog / Notch | | | 3 | Signaling by GPCR | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for MOB1A
2 
Reactome Pathways for MOB1A
MOB1A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MOB1A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/58 Interacting proteins for MOB1A (Q9H8S91, 2, 3 ENSP000003793644) via UniProtKB, MINT, STRING, and/or I2D (see all 58)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CCDC85B | Q158342, 3, ENSP000003116954 | MINT-68190 I2D:
score=5 STRING: ENSP00000311695 | | STK38 | Q152081, 3, ENSP000002298124 | EBI-748229,EBI-458376 I2D:
score=2 STRING: ENSP00000229812 | | LATS1 | O958351, 3, ENSP000002533394 | EBI-748229,EBI-444209 I2D:
score=1 STRING: ENSP00000253339 | | LATS2 | Q9NRM71, 3, ENSP000003720354 | EBI-748229,EBI-3506895 I2D:
score=1 STRING: ENSP00000372035 | | KXD1 | Q9BQD32, 3, ENSP000002223074 | MINT-67233 I2D:
score=4 STRING: ENSP00000222307 |
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0035329 | hippo signaling cascade |
TAS | -- |
MOB1A for ontologies About GeneDecksing
|
Drugs & Compounds
for MOB1A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MOB1A
Search CenterWatch for drugs/clinical trials and news about MOB1A
|
Transcripts
for MOB1A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MOB1A gene: NM_018221.3 Unigene Cluster for MOB1A: MOB kinase activator 1A Hs.602092 [show with all ESTs]Unigene Representative Sequence: AK1238657 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396049(uc002skh.4) ENST00000497054 ENST00000495286 ENST00000463975(uc002ski.2)
ENST00000488006 ENST00000494600 ENST00000409969
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MOB1A | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MOB1A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB1A |
Additional cDNA sequence: AB016839.1 AJ577474.1 AK001650.1 AK021657.1 AK023321.1 AK123865.1 AL122062.1 BC003398.1 18 DOTS entries: DT.75147897 DT.95266547 DT.91647641 DT.120938020 DT.100655804 DT.100655806 DT.424949 DT.92452595 DT.120937983 DT.100655803 DT.91665813 DT.95266540 DT.87015892 DT.92452592 DT.92452593 DT.95266554 DT.99953352 DT.87005796 24/461 AceView cDNA sequences (see all 461): AA987966 BQ229025 BM551597 AI393039 BQ000981 BX482184 AI985784 BM728912 BU539055 AW173555 BU152863 BG771348 AA188376 BU608335 AI806922 CB121100 BM767043 CD672806 AI673292 BQ430327 AA604351 AI655298 AI434784 BU681933
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for MOB1A (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MOB1A
|
Expression
for MOB1A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MOB1A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGGTGTACA
About this image
See MOB1A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MOB1A
SOURCE GeneReport for Unigene cluster: Hs.602092
UniProtKB/Swiss-Prot: MOB1A_HUMAN, Q9H8S9Tissue specificity: Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis,thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver
SABiosciences Custom PCR Arrays for MOB1A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MOB1A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MOB1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOB1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOB1A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB1A |
Orthologs
for MOB1A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MOB1A gene from 7/28 species (see all 28) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC4296571 |
mps one binder kinase activator-like 1B-like |
82.87(n)
98.61(a) |
|
429657 XM_427212.3 XP_427212.3 |
African clawed frog
(Xenopus laevis) |
Amphibia |
MOB12 |
MOB1 protein |
81.52(n) |
|
AY319763.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufv69d042 |
wufv69d04 |
79.45(n) |
|
334574 BC045979.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
mats6 |
mob as tumor suppressor |
84(a) |
1 → many |
3R(18246877-18248568) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
MOB11 |
Mob1p |
55.07(n)
51.69(a) |
|
854700 NP_012160.2 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G455506AT4G190456 |
Mob1/phocein family protein |
66(a)65(a) |
many ↔ manymany ↔ many |
5(18462162-18465097) 4(10438024-10439900) |
rice
(Oryza sativa) |
Liliopsida |
Os10g03963001 |
hypothetical protein |
65.09(n)
65.88(a) |
|
4348552 NM_001071066.1 NP_001064531.2 |
ENSEMBL Gene Tree for MOB1A (if available)
TreeFam Gene Tree for MOB1A (if available) |
Paralogs
for MOB1A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MOB1A gene
- MOB3C2 MOB22 MOB3A2 MOB3B2 MOB1B2
8 SIMAP similar genes for MOB1A using alignment to 2 protein entries: MOB1A_HUMAN (see all proteins):MOB4A MOB1B MOBKL1A MOB3A DKFZp686N2312 MOB3C
MOB3B MOB2
MOB1A for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for MOB1A
PGOHUM00000248654 PGOHUM00000241707
|
Genomic Variants
for MOB1A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MOB1A (74382165 - 74406025 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MOB1A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MOB1A |
|
Disorders
/ Diseases
for MOB1A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MOB1A for disorders About GeneDecksing
OMIM gene information: 609281
OMIM disorders: --
3  diseases for MOB1A: About MalaCardscolorectal cancer thyroiditis prostatitis
Export disorders for MOB1A gene to outside databases
|
Publications
for MOB1A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MOB1A gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with MOB1A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR ki nases. (PubMed id 20624913)1, 3 Kohler R.S....Hergovich A. (2010)
- Molecular characterization of human homologs of yeast MOB1. (PubMed id 19739119)1, 2 Chow A....Yang X. (2010)
- Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. (PubMed id 18362890)1, 2 Hirabayashi S....Hata Y. (2008)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein. (PubMed id 15197186)1, 2 Bichsel S.J.... Hemmings B.A. (2004)
- Crystal structure of a human Mob1 protein: toward understanding Mob- regulated cell cycle pathways. (PubMed id 12962634)1, 2 Stavridi E.S.... Luca F.C. (2003)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes. (PubMed id 11319234)1, 3 Moreno C.S....Pallas D.C. (2001)
|
External Searches for MOB1A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MOB1A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MOB1A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MOB1A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MOB1A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MOB1A gene:
Search GeneIP for patents involving MOB1A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MOB1A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MOB1A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MOB1A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MOB1A | | | OriGene Protein Over-expression Lysate for MOB1A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MOB1A | | OriGene 3'-UTR Clone for MOB1A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MOB1A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MOB1A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MOB1A | | OriGene Custom Protein Services for MOB1A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MOB1A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MOB1A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOB1A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MOB1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MOB1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MOB1A |
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| | Antibodies & Assays for MOB1A |
| | | | Search Tocris compounds for MOB1A |
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 | | | MOB1A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MOB1A |
|  |  |  | | | | ThermoFisher Antibodies for MOB1A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MOB1A |
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