Aliases for MNX1 Gene
External Ids for MNX1 Gene
Previous HGNC Symbols for MNX1 Gene
Previous GeneCards Identifiers for MNX1 Gene
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for MNX1 Gene
MNX1 (Motor Neuron And Pancreas Homeobox 1) is a Protein Coding gene. Diseases associated with MNX1 include Currarino Syndrome and Imperforate Anus. Among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Regulation of beta-cell development. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is GBX2.
UniProtKB/Swiss-Prot for MNX1 Gene
Putative transcription factor involved in pancreas development and function.