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MN1 Gene

protein-coding GIFtS: 51

GC22M026468

meningioma (disrupted in balanced translocation) 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MGCR ^², ⁵
MGCR1 ^²
MGCR1-PEN ^¹, ²
OTTHUMP00000028743 ^²
dJ353E16.2 ^²

Descriptions
bK437G10B.1 (meningioma (disrupted in balanced translocation) 1) ^²
meningioma (disrupted in balanced translocation) 1 ^²
meningioma (translocation balanced) ^²
meningioma 1 ^²
meningioma chromosome region 1 ^²
probable tumor suppressor protein MN1 ^²

External Ids
HGNC: 7180¹
Entrez Gene: 4330²
UniProtKB: Q10571³
Ensembl: ENSG00000169184⁷

Search outside databases for aliases for MN1 gene

Previous GC identifer: GC22M024840

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MN1:

Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation

(4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.

[provided by RefSeq]

UniProtKB/Swiss-Prot: MN1_HUMAN, Q10571

Function: May play a role in tumor suppression

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MN1 gene

Entrez Gene cytogenetic band: 22q11|22q12.1 Ensembl cytogenetic band: 22q12.1 HGNC cytogenetic band: 22q12.1

MN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22M026468: (about GC identifiers)

Start:	26,474,265 bp from pter
End:	26,527,486 bp from pter
Size:	53,222 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MN1_HUMAN, Q10571 (See protein sequence)

Recommended Name: Probable tumor suppressor protein MN1

Size: 1320 amino acids; 136001 Da

Secondary accessions: A9Z1V9

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002421.3

ENSEMBL proteins:

ENSP00000304956

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MN1)
	Human Recombinant Proteins from Abnova (MN1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005634	nucleus	IDA	18029348

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Antibodies for MN1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MN1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (MN1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for MN1

Assays for MN1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q10571

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MN1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002430

Applied Biosystems Silencer® siRNAs for MN1

Sigma-Aldrich siRNA for MN1

Sigma-Aldrich shRNA for MN1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002430
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002430
untagged cDNA clone in CMV expression vector: NM_002430

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002430

UniProtKB/Swiss-Prot: MN1_HUMAN, Q10571

Function: May play a role in tumor suppression

8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mn1):

behavior/neurological	craniofacial	digestive/alimentary	homeostasis/metabolism	lethality-prenatal/perinatal
respiratory system	skeleton	tumorigenesis

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for MN1

5/7 Interacting proteins for MN1 (ENSP00000304956³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ETV6	ENSP00000266427³	STRING (score=.905)
DHRS9	ENSP00000350154³	STRING (score=.89)
IGFBP5	ENSP00000233813³	STRING (score=.871)
AP1B1	ENSP00000350199³	STRING (score=.802)
CHIC2	ENSP00000263921³	STRING (score=.78)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--
GO:0045786	negative regulation of cell cycle	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MN1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MN1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002430

Sigma-Aldrich siRNA for MN1

Sigma-Aldrich shRNA for MN1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002430

REFSEQ mRNAs for MN1 gene:

NM_002430.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002430

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002430
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002430
                                 untagged cDNA clone in CMV expression vector: NM_002430

Additional cDNA sequence:

AK307152.1 X82209.2 Z70218.1

3 DOTS entries:

DT.313671 DT.120648456 DT.95157898

24/61 AceView cDNA sequences (see all 61 ):

AA340204 BQ446922 CB132163 BQ017335 BU158459 AI338832 BF530976 BI914686

AA339316 BE045553 Z39850 AA340193 AU118290 BM821195 BF433623 AW043606

AL134518 BQ067881 BI497169 BM927002 BG059788 D51800 CF264930 Z28469

highest scoring ESTs for MN1:

X82209 AA339316 AA340193 AA340204 AA928721 AI277624 AI290447 AI307241 AI334967 AI637666

Unigene Cluster for MN1:

Meningioma (disrupted in balanced translocation) 1

Hs.268515 [show with all ESTs]

Unigene Representative Sequence: NM_002430

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000302326

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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MN1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MN1

¹ / ² / ³

4 probe-sets matching MN1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37283_at²^{, 3}	U95-A	1	1.00	1.00	0.96	1.54	X82209	1.00	1.00	1.00	1
31486_s_at²^{, 3}	U95-A	1	1.00	1.00	0.85	0.51	Z70218	0.60	1.00	0.82	1
205330_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002430	0.60	1.00	0.82	1
205330_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MN1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AAATTGAGTG

SOURCE GeneReport for Unigene cluster: Hs.268515
Expression variation in blood from EXPOLDB for MN1
UniProtKB/Swiss-Prot: MN1_HUMAN, Q10571
Tissue specificity: Ubiquitously expressed. Highest levels in skeletal muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MN1 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
cow (Bos taurus)	MN1¹	--	meningioma (disrupted in balanced translocation) 1	83.24(n) 83.82(a)	786290 XM_001254017.1 XP_001254018.1
rat (Rattus norvegicus)	Mn1¹	--	meningioma 1	85.69(n) 91.24(a)	498194 XM_573413.2 XP_573413.2
mouse (Mus musculus)	Mn1^{1, 5}	5 (59.00 cM)⁵	meningioma 1^{1, 5}	85.81(n)¹ 91.21(a)¹	433938¹ NM_001081235.1¹ NP_001074704.1¹ AA003644⁵ AA009236⁵ (see all 8)
zebrafish (Danio rerio)	LOC572077¹	--	similar to meningioma 1	62.14(n) 60.21(a)	572077 XM_001919740.1 XP_001919775.1
tropical clawed frog (Silurana tropicalis)	137723142²	--	--	84.16(n)	137723142

About this table Species with no ortholog for MN1

ENSEMBL Gene Tree for MN1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/518 NCBI SNPs in MN1 are shown (see all 518 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 146)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs6005627^1,2	A,C,F,H	26528577(+)	`CCCAGA/GCCCTC`	1	--	ng3¹		9	EU EA WA NS	600
	rs8136754^1,2	A,C,F,H	26527815(+)	`CGGGCT/CCGGGG`	1	--	ng3¹		11	EA WA NS	782
	rs6519725^1,2	A,C,F,H	26475925(+)	`GAGAAC/TAGCCT`	1	--	ut3¹ ese³		13	EU EA WA NS	1026
	rs3788407^1,2	A,C,F,H	26529417(+)	`aatttT/Gaatta`	1	--	ng3¹ tfbs³		9	EU EA WA NS	590
	rs5762340^1,2	C,F,H	26474624(+)	`TATTCT/GTTCCA`	1	--	ut3¹		12	EU EA WA NA NS	734
	rs5752632^1,2	C,F,H	26475148(+)	`GGACCG/AGCAGA`	1	--	ut3¹ ese³		12	EU EA WA NA NS	684
	rs17476776^1,2	C,F,H	26475605(+)	`TGCAAC/TAGGGT`	1	--	ut3¹ ese³		11	NA EU EA WA	982
--	rs41277851^1,2	C,F	26476277(+)	`CAGGCG/AGAATA`	1	--	ut3¹		5	NS	182
--	rs41277849^1,2	C,F	26475327(+)	`GGGGTG/AGGGGA`	1	--	ut3¹		5	NS	170
--	rs9613530^1,2	C,F	26527126(+)	`GATCCG/ACTCGC`	1	--	ut5¹		5	NS	190

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HapMap Linkage Disequilibrium images for MN1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 156100 disorders: 607174

UniProtKB/Swiss-Prot: MN1_HUMAN, Q10571

A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML).

Translocation t(12;22)(p13;q11) with TEL

Defects in MN1 may be a cause of meningiomas, slowly growing benign tumors derived from

the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord.

Meningiomas are believed to be the most common primary tumors of the central nervous system in man

4 Novoseek disease relationships for MN1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
meningioma	68.94	5	7731706 (3), 18632758 (1), 17242174 (1)
chromosomal aberrations	46.54	1	17335728 (1)
leukemia	32.73	1	18632758 (1)
tumors	0.00	2	16398473 (1), 17335728 (1)

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Human Genome Epidemiology Navigator: MN1 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/24 PubMed articles for MN1 gene (see all 24 ):

Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. (PubMed id 7731706)^{1, 2, 3, 4} Deprez R.H.L.... Zwarthoff E.C. (1995)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription. (PubMed id 12569362)^{2, 3} van Wely K.H....Zwarthoff E.C. (2003)
MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression. (PubMed id 18632758)^{1, 3} Meester-Smoor M.A....Zwarthoff E.C. (2008)
The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence. (PubMed id 17242174)^{1, 3} Meester-Smoor M.A....Zwarthoff E.C. (2007)
Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. (PubMed id 7731705)^{1, 3} Buijs A....Hagemeijer A. (1995)
Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)³ Trynka G....Wijmenga C. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
MN1 overexpression is an important step in the development of inv(16) AML. (PubMed id 17525718)³ Carella C....Grosveld G.C. (2007)
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. (PubMed id 17494859)³ Heuser M....Humphries R.K. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 4330	HGNC: 7180	AceView: MN1	Ensembl:ENSG00000169184	euGenes: HUgn4330
ECgene: MN1	H-InvDB: MN1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for MN1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MN1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for MN1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MN1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MN1		Antibodies for MN1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MN1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Recombinant & Natural Proteins

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MN1 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for MN1

Summaries
for MN1

Genomic Location
for MN1

Proteins
for MN1

Protein Domains/
Families
for MN1

Gene Function
for MN1

Pathways & Interactions
for MN1

Drugs & Compounds
for MN1

Transcripts
for MN1

Expression
for MN1

Orthologs
for MN1

Paralogs
for MN1

SNPs/Variants
for MN1

Disorders & Mutations
for MN1

Medical News
for MN1

Publications
for MN1

Search for MN1

Genome Databases showing MN1

Other Databases showing MN1

Specialized Databases showing MN1

Licensable Technologies
for MN1

Services
for MN1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MN1 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor MN1

Summariesfor MN1

Genomic Locationfor MN1

Proteinsfor MN1

Protein Domains/Familiesfor MN1

Gene Functionfor MN1

Pathways & Interactionsfor MN1

Drugs & Compoundsfor MN1

Transcriptsfor MN1

Expression for MN1

Orthologsfor MN1

Paralogsfor MN1

SNPs/Variantsfor MN1

Disorders & Mutationsfor MN1

Medical Newsfor MN1

Publicationsfor MN1

Search for MN1

Genome Databases showing MN1

Other Databases showing MN1

Specialized Databases showing MN1

Licensable Technologiesfor MN1

Servicesfor MN1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MN1

Summaries
for MN1

Genomic Location
for MN1

Proteins
for MN1

Protein Domains/
Families
for MN1

Gene Function
for MN1

Pathways & Interactions
for MN1

Drugs & Compounds
for MN1

Transcripts
for MN1

Expression
for MN1

Orthologs
for MN1

Paralogs
for MN1

SNPs/Variants
for MN1

Disorders & Mutations
for MN1

Medical News
for MN1

Publications
for MN1

Licensable Technologies
for MN1

Services
for MN1