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MMS22L Gene

protein-coding   GIFtS: 45
GCID: GC06M097590

MMS22-Like, DNA Repair Protein

(Previous name: chromosome 6 open reading frame 167)
(Previous symbol: C6orf167)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MMS22-Like, DNA Repair Protein1 2
C6orf1671 2 3 5
Chromosome 6 Open Reading Frame 1671
dJ39B17.22
Protein MMS22-Like2
Methyl Methanesulfonate-Sensitivity Protein 22-Like3

External Ids:    HGNC: 214751   Entrez Gene: 2537142   Ensembl: ENSG000001462637   OMIM: 6156145   UniProtKB: Q6ZRQ53   

Export aliases for MMS22L gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MMS22L Gene:
MMS22L (MMS22-like, DNA repair protein) is a protein-coding gene.

UniProtKB/Swiss-Prot: MMS22_HUMAN, Q6ZRQ5
Function: Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of
stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during
DNA replication by promoting homologous recombination-mediated repair of replication fork-associated
double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA

Gene Wiki entry for MMS22L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MMS22L
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MMS22L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MMS22L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16.1   Ensembl cytogenetic band:  6q16.1   HGNC cytogenetic band: 6q16.3

MMS22L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MMS22L gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M097590:  view genomic region     (about GC identifiers)

Start:
97,590,037 bp from pter      End:
97,731,093 bp from pter
Size:
141,057 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MMS22_HUMAN, Q6ZRQ5 (See protein sequence)
Recommended Name: Protein MMS22-like  
Size: 1243 amino acids; 142321 Da
Subunit: Component of the MMS22L-TONSL complex, a complex at least composed of MMS22L and TONSL/NFKBIL2
Sequence caution: Sequence=CAI16668.1; Type=Erroneous gene model prediction; Sequence=CAI20426.1; Type=Erroneous
gene model prediction;
Secondary accessions: D6R9Y8 D6RBQ4 E1P529 Q5THT2 Q68CQ6 Q68D32

Explore the universe of human proteins at neXtProt for MMS22L: NX_Q6ZRQ5

Explore proteomics data for MMS22L at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys54
  • Modification sites at PhosphoSitePlus

  • See MMS22L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_940870.2  
    ENSEMBL proteins: 
     ENSP00000275053   ENSP00000358254   ENSP00000422627   ENSP00000427288   ENSP00000421225  
     ENSP00000422045  

    MMS22L Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for MMS22L
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MMS22L

     
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    antibodies-online peptides for MMS22L

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    antibodies-online kits for MMS22L (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q6ZRQ5

    UniProtKB/Swiss-Prot: MMS22_HUMAN, Q6ZRQ5
    Similarity: Belongs to the MMS22 family. MMS22L subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MMS22_HUMAN, Q6ZRQ5
    Function: Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of
    stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during
    DNA replication by promoting homologous recombination-mediated repair of replication fork-associated
    double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with MMS22L           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for MMS22L:
     Cell division defect  Increased G2M DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MMS22L

    miRNA
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    miRTarBase miRNAs that target MMS22L:
    hsa-mir-101-3p (MIRT027328), hsa-mir-128-3p (MIRT022097), hsa-mir-1 (MIRT024010), hsa-let-7b-5p (MIRT005233), hsa-mir-27a-3p (MIRT028710), hsa-mir-155-5p (MIRT020971), hsa-mir-320a (MIRT044825)

    Block miRNA regulation of human, mouse, rat MMS22L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MMS22L (see all 22):
    hsa-miR-142-5p hsa-miR-549 hsa-miR-4328 hsa-miR-429 hsa-miR-500a hsa-miR-23b* hsa-miR-29a* hsa-miR-200b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MMS22L

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: MMS22L (NM_198468)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMS22L

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMS22L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MMS22_HUMAN, Q6ZRQ5: Nucleus. Note=Localizes to DNA damage sites, accumulates at stressed replication forks

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035101colocalizes with FACT complex IDA--
    GO:0042555colocalizes with MCM complex IDA--
    GO:0043596nuclear replication fork IDA--

    Find genes that share ontologies with MMS22L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MMS22L
    Interactions:

        Search GeneGlobe Interaction Network for MMS22L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for MMS22L (Q6ZRQ51, 2, 3 ENSP000002750534) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSRP1Q089452, 3, ENSP000002784124MINT-8089790 I2D: score=1 STRING: ENSP00000278412
    TONSLQ96HA71, 2, 3, ENSP000003862394EBI-718662,EBI-1052467 MINT-8089662 MINT-8089673 MINT-8089726 MINT-8089667 MINT-8089790 I2D: score=2 STRING: ENSP00000386239
    MCM2P497362, 3, ENSP000002650564MINT-8089673 MINT-8089790 I2D: score=1 STRING: ENSP00000265056
    ASF1BQ9NVP22, 3, ENSP000002633824MINT-8089726 MINT-8089790 I2D: score=2 STRING: ENSP00000263382
    MCM4P339912, 3, ENSP000002621054MINT-8089790 I2D: score=1 STRING: ENSP00000262105
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000724double-strand break repair via homologous recombination IMP--
    GO:0031297replication fork processing IMP--

    Find genes that share ontologies with MMS22L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MMS22L (MMS22)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MMS22L gene: 
    NM_198468.2  

    Unigene Cluster for MMS22L:

    MMS22-like, DNA repair protein
    Hs.444292  [show with all ESTs]
    Unigene Representative Sequence: NM_198468
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000275053(uc011eaf.2 uc003ppb.3) ENST00000369251 ENST00000514790
    ENST00000509383(uc010kcn.1) ENST00000510018 ENST00000482634 ENST00000508976(uc003ppc.3)
    ENST00000511335 ENST00000506256 ENST00000484170 ENST00000508820 ENST00000496119

    miRNA
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    Block miRNA regulation of human, mouse, rat MMS22L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MMS22L (see all 22):
    hsa-miR-142-5p hsa-miR-549 hsa-miR-4328 hsa-miR-429 hsa-miR-500a hsa-miR-23b* hsa-miR-29a* hsa-miR-200b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MMS22L
    Predesigned siRNA for gene silencing in human, mouse, rat MMS22L
    Clone
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    OriGene clones in human, mouse for MMS22L (see all 7)
    OriGene ORF clones in mouse, rat for MMS22L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MMS22L (NM_198468)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MMS22L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMS22L
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MMS22L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MMS22L
      QuantiTect SYBR Green Assays in human, mouse, rat MMS22L
      QuantiFast Probe-based Assays in human, mouse, rat MMS22L

    Additional mRNA sequence: 

    AK128060.1 BC110860.1 BC142948.1 BX538214.1 CR749603.1 CR749822.1 

    10 DOTS entries:

    DT.99937339  DT.121334382  DT.40128770  DT.121334384  DT.91815896  DT.206471  DT.40203160  DT.91683094 
    DT.75154045  DT.121334360 

    Selected AceView cDNA sequences (see all 64):

    BX101433 BU632144 AI656894 BE018528 BX280669 AI590578 BF445436 AA669669 
    CR601989 CB122571 CA429386 CR749822 AA905574 BE302127 BX108098 BX422070 
    CR603418 BX342404 AI379624 BG531385 BU195667 AI472349 AK128060 BG504187 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MMS22L (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^
    SP1:                                                                                                              -                                             
    SP2:                                -                                                                                                                           
    SP3:                          -     -                 -                                                                                                         
    SP4:                          -     -                       -     -     -     -     -                                                                           
    SP5:                          -     -                                                                                                                           

    ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for MMS22L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MMS22L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAAAAGGT
    MMS22L Expression
    About this image

    MMS22L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MMS22L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444292
        Custom PCR Arrays for MMS22L
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    QuantiFast Probe-based Assays in human, mouse, rat MMS22L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMS22L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MMS22L gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mms22l1 , 5 MMS22-like, DNA repair protein1, 5 83.62(n)1
    81(a)1
      4 (10.36 cM)5
    2123771  NM_199467.21  NP_955761.21 
     244964515 
    chicken
    (Gallus gallus)
    Aves MMS22L1 MMS22-like, DNA repair protein 68.95(n)
    62.02(a)
      421799  XM_419826.4  XP_419826.4 
    lizard
    (Anolis carolinensis)
    Reptilia MMS22L6
    MMS22-like, DNA repair protein
    58(a)
    1 ↔ 1
    1(173346650-173449649)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mms22l1 MMS22-like, DNA repair protein 61.28(n)
    58.64(a)
      100158637  NM_001128044.1  NP_001121516.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mms22l1 MMS22-like, DNA repair protein 54.93(n)
    48.88(a)
      563411  NM_001130601.1  NP_001124073.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG148036
    --
    20(a)
    1 ↔ 1
    X(1762821-1766384)


    ENSEMBL Gene Tree for MMS22L (if available)
    TreeFam Gene Tree for MMS22L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MMS22L (see all 2649)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs763973301,2
    F--97589588(+) TTCTAT/CAGGAA 1 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1857451641,2
    --97589824(+) CTTCAA/TATTTT 1 -- ds50010--------
    rs1151909901,2
    F--97589945(+) AAATTA/GTTACT 1 -- ds50011Minor allele frequency- G:0.04WA 118
    rs1999949441,2
    C--97590062(+) ATTAT-/TATA  
            
    TATAA
    1 -- ut310--------
    rs1892934601,2
    --97590096(+) ACTCAC/TAAATA 1 -- ut310--------
    rs783226891,2
    C,F--97590163(+) TGAATT/AGGATA 1 -- ut311Minor allele frequency- A:0.04WA 118
    rs1809744791,2
    --97590193(+) TTTTAA/GTAAGT 1 -- ut310--------
    rs1417989961,2
    --97590233(+) ATTTAC/TAATGC 1 -- ut310--------
    rs797732761,2
    C--97590240(+) ATGCAA/GGTTAT 1 -- ut310--------
    rs1386077891,2
    C--97590308(+) CCCAAA/TCCAAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MMS22L (97590037 - 97731093 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MMS22L:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2485949CNV Deletion19546169
    esv2541663CNV Insertion19546169
    nsv886426CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MMS22L
    DNA2.0 Custom Variant and Variant Library Synthesis for MMS22L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615614    OMIM disorders: --


    Find genes that share disorders with MMS22L           About GenesLikeMe


    Export disorders for MMS22L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MMS22L gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with MMS22L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the MMS22L-TONSL complex that promotes homologous recombination. (PubMed id 21055984)1, 2, 3 Duro E.... Rouse J. (Mol. Cell 2010)
    2. The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. (PubMed id 21055983)1, 2, 3 O'Donnell L.... Durocher D. (Mol. Cell 2010)
    3. A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. (PubMed id 21055985)1, 2 O'Connell B.C.... Harper J.W. (Mol. Cell 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. (PubMed id 23785401)1 Leone M.A....D'Alfonso S. (PLoS ONE 2013)
    7. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis. (PubMed id 22895565)1 Nguyen M.H....Daigo Y. (Int. J. Oncol. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 253714 HGNC: 21475 AceView: C6orf167 Ensembl:ENSG00000146263 euGenes: HUgn253714
    ECgene: MMS22L H-InvDB: MMS22L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MMS22L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MMS22L gene:
    Search GeneIP for patents involving MMS22L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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