MMP26 Gene
protein-coding GIFtS: 56
GCID: GC11P004726
|
|
matrix metallopeptidase 26(Previous name: matrix metalloproteinase 26 )
| |
Aliases
for MMP26 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Matrix Metallopeptidase 261 2 | | Matrilysin 22 | | Endometase3 | | Matrilysin-23 | | Matrix Metalloproteinase 261 2 | | Matrix Metalloproteinase-262 | | MMP-262 3 | | EC 3.4.24.-3 | | MGC1265901 | | Endometase3 | | MGC1265921 | | Matrilysin-23 |
Export aliases for MMP26 gene to outside databasesPrevious GC identifers: GC11P005575 GC11P005311 GC11P004968 GC11P004973 GC11P004966 GC11P004745 GC11P004669 |
Summaries
for MMP26 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MMP26:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated whencleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein,vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, andactivates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminalprotein domain. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MMP26_HUMAN, Q9NRE1Function: May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinaseinhibitor. Is also able to activate progelatinase B
 summary
for MMP26: Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent
endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a
wide range of extracellular molecules and a number of bioactive molecules. 24 matrixin genes have been
identified in humans, which can be organized into six groups based on domain organization and substrate
preference: Collagenases (MMP-1, -8 and -13), Gelatinases (MMP-2 and MMP-9), Stromelysins (MMP-3, -10 and
-11), Matrilysin (MMP-7 and MMP-26), Membrane-type (MT)-MMPs (MMP-14, -15, -16, -17, -24 and -25) and others
(MMP-12, -19, -20, -21, -23, -27 and -28). MMP activity is regulated by two major endogenous inhibitors:
alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMPs play a central role in cell
proliferation, migration, differentiation, angiogenesis, apoptosis and host defences. Dysregulatoin of MMPs
has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis and cancer.
Tumour metastasis is a multistep process involving the dessemination of tumor cells from the primary tumor
to secondarys at a distant organ or tissue. One of the first steps in metastasis is the degradation of the
basement membrane, a process in which MMPs have been implicated. MMPs are secreted by tumor cells themselves
or by surrounding stromal cells stimulated by the nearby tumor. Numerous studies have linked altered MMP
expression in different human cancers with poor disease prognosis. MMP-1, -2, -3, -7, -9, -13 and -14 all
have elevated expression in primary tumors and/or metastases. Synthetic or natural inhibitors of MMPs result
in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.
Gene Wiki entry for MMP26
|
Genomic Views
for MMP26 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MMP26 gene promoter:
p53 SREBP-1c CUTL1 Tal-1beta HNF-3beta LCR-F1 SREBP-1b PPAR-alpha SREBP-1a ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for MMP26
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMP26 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15MMP26 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P004726: view genomic region
(about GC identifiers)
Start:
|
4,726,157 bp from pter |
End:
|
5,013,659 bp from pter |
Size:
|
287,503 bases |
Orientation:
|
plus strand |
|
Proteins
for MMP26 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MMP26_HUMAN, Q9NRE1 (See
protein sequence)Recommended Name: Matrix metalloproteinase-26 precursor Size: 261 amino acids; 29708 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Cofactor: Calcium (By similarity)
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: Q3MJ78 Q9GZS2 Q9NR87Explore the universe of human proteins at neXtProt for MMP26: NX_Q9NRE1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRE1
MMP26 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_068573.2
ENSEMBL proteins: ENSP00000369753 ENSP00000300762
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005578 | proteinaceous extracellular matrix |
NAS | 10801841 |
MMP26 for ontologies About GeneDecksing
MMP26 Antibody Products:
Assay Products for MMP26: |
Protein
Domains /
Families
for MMP26 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MMP26 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NRE1ProtoNet protein and cluster: Q9NRE1 UniProtKB/Swiss-Prot: MMP26_HUMAN, Q9NRE1Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting theenzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzymeSimilarity: Belongs to the peptidase M10A family |
Function
for MMP26 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MMP26_HUMAN, Q9NRE1Function: May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinaseinhibitor. Is also able to activate progelatinase BEnzyme Number (IUBMB): EC 3.4.24.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MMP26 (NM_021801) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MMP26 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP26 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP26 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004222 | metalloendopeptidase activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
MMP26 for ontologies About GeneDecksing
|
Pathways & Interactions
for MMP26 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Matrix Metalloproteinases | | | 2 | Integrin Pathway | | | 3 | GPCR Pathway | |
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MMP26
1  BioSystems Pathway for MMP26
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MMP26
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for MMP26 (Q9NRE13 ENSP000003007624) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
MMP26 for ontologies About GeneDecksing
|
Drugs & Compounds
for MMP26 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MMP26 for compounds About GeneDecksing
Compounds for MMP26 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| CP 471474 | Broad spectrum MMP inhibitor | [210755-45-6] | | Marimastat | Broad spectrum MMP inhibitor | [154039-60-8] | | ONO 4817 | Broad spectrum MMP inhibitor | [223472-31-9] | | Batimastat | Potent, broad spectrum MMP inhibitor | [130370-60-4] | | PD 166793 | Broad spectrum MMP inhibitor | [199850-67-4] |
1 HMDB Compound for MMP26 About this table
1 DrugBank Compound for MMP26 About this table
6 Novoseek chemical compound relationships for MMP26 gene About this table
Search CenterWatch for drugs/clinical trials and news about MMP26
|
Transcripts
for MMP26 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MMP26 gene: NM_021801.3 Unigene Cluster for MMP26: Matrix metallopeptidase 26 Hs.204732 [show with all ESTs]Unigene Representative Sequence: AF2486463 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000477339 ENST00000380390(uc001lzv.3) ENST00000300762
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MMP26 (NM_021801) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MMP26 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP26 |
Additional cDNA sequence: AF230354.1 AF248646.1 AF291664.1 AJ251531.1 BC101541.1 BC101543.1 1 DOTS entry: DT.433369 14 AceView cDNA sequences: BX281588 BG189720 AA336600 AI743415 AF248646 AJ251531 AF230354 BX094260 BI831623 NM_021801 AF291664 AA336367 BG198356 AW966183
GeneLoc Exon Structure
|
Expression
for MMP26 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MMP26 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATATGAAGCC
About this image
See MMP26 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MMP26
SOURCE GeneReport for Unigene cluster: Hs.204732
UniProtKB/Swiss-Prot: MMP26_HUMAN, Q9NRE1Tissue specificity: Expressed specifically in uterus and placenta. Is also widely expressed in malignant tumors fromdifferent sources as well as in diverse tumor cell lines
SABiosciences Custom PCR Arrays for MMP26
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMP26
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MMP26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP26 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP26 |
Orthologs
for MMP26 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MMP26 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for MMP26 (if available)
TreeFam Gene Tree for MMP26 (if available) |
Paralogs
for MMP26 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MMP26 gene
- MMP212 MMP23B2 MMP192 MMP72
18 SIMAP similar genes for MMP26 using alignment to 1 protein entry: MMP26_HUMAN:MMP7 MMP8 MMP2 MMP11 MMP13 MMP20
MMP27 MMP28 MMP10 MMP12 MMP17 MMP1
MMP3 MMP16 MMP19 MMP14 MMP24 MMP15
MMP26 for paralogs About GeneDecksing
|
Genomic Variants
for MMP26 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MMP26 (4726157 - 4976157 bp, first 250kb of MMP26)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MMP26
1 CNV: 3835 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MMP26 |
|
Disorders
/ Diseases
for MMP26 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MMP26 for disorders About GeneDecksing
OMIM gene information: 605470
OMIM disorders: --
20/33  diseases for MMP26 (see all 33): About MalaCardsencephalomyelitis arthritis pyoderma gangrenosum pyoderma
polycystic ovary syndrome esophageal squamous cell carcinoma squamous cell carcinoma aggressive periodontitis
coronary heart disease ductal carcinoma in situ skin disease endometrial carcinoma
periodontitis endometrial cancer carcinoma kawasaki disease
celiac disease prostate cancer prostate cancer, progression of multiple sclerosis
10/22 Novoseek disease relationships for MMP26 gene (see all 22) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| endometrial hyperplasia |
40.7 |
2 |
15350356 (1) |
| squamous cell cancer |
40.1 |
1 |
15816845 (1) |
| hyperplasia |
34.6 |
4 |
19448419 (3), 14744773 (1) |
| cancer |
34.2 |
24 |
11389678 (3), 19674198 (2), 16510592 (2), 19895737 (2) (see all 15) |
| endometrial carcinoma |
33.9 |
9 |
12491508 (4), 12798711 (3) |
| carcinoma |
30.8 |
17 |
19818727 (1), 12798711 (1), 15006646 (1), 11389678 (1) (see all 9) |
| invasive cancer |
29.4 |
2 |
16940965 (1), 14694517 (1) |
| inflammation |
25.4 |
6 |
15816845 (2), 15574774 (1), 16584348 (1), 16641547 (1) |
| premalignant |
21.4 |
6 |
15779297 (3), 15350356 (2) |
| carcinoma ductal |
19.8 |
1 |
16510592 (1) |
Human Genome Epidemiology (HuGE) Navigator: MMP26 (5 documents)
Export disorders for MMP26 gene to outside databases
|
Publications
for MMP26 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MMP26 gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with MMP26) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of Homo sapiens endometase (matrix metalloproteinase-26) from endometrial tumor. (PubMed id 10801841)1, 2, 3, 9 Park H.I.... Sang Q.-X.A. (2000)
- Cloning of MMP-26 A novel matrilysin-like proteinase. (PubMed id 10824119)1, 2, 3, 9 Begnoit de Coignac A....Gauchat J.-F. (2000)
- Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin. (PubMed id 11389678)1, 2, 9 Marchenko G.N.... Strongin A.Y. (2001)
- Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity. (PubMed id 10987280)1, 2, 9 Uria J.A. and Lopez-Otin C. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Expression of Matrix Metalloproteinase-26 promotes hu man glioma U251 cell invasion in vitro and in vivo. (PubMed id 19956866)1, 9 Deng Y....Li Y. (2010)
- Matrix metalloproteinase-26 (matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer. (PubMed id 15350356)1, 9 Pilka R....Casslen B. (2004)
- Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells. (PubMed id 12586837)1, 9 Zhao Y.G....Sang Q.X. (2003)
- Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma. (PubMed id 15333466)1, 9 Yamamoto H....Imai K. (2004)
- GnRH I and II up-regulate MMP-26 expression through t he JNK pathway in human cytotrophoblasts. (PubMed id 20074375)1, 9 Liu J....Wang Y.L. (2010)
|
External Searches for MMP26 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MMP26 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MMP26 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MMP26 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MMP26 gene:
Search GeneIP for patents involving MMP26
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MMP26 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MMP26 | | OriGene shRNA RFP for MMP26 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MMP26 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMP26 | | | OriGene Protein Over-expression Lysate for MMP26 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MMP26 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP26 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MMP26 | | OriGene Custom Protein Services for MMP26 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MMP26 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MMP26 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMP26 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMP26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP26 |
| |
 |  |  |  | |
| | | | Tocris compounds for MMP26 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MMP26 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP26 |
|  |  |  | | | | ThermoFisher Antibodies for MMP26 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP26 |
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