MMP23B Gene
protein-coding GIFtS: 56
GCID: GC01P001559
|
|
matrix metallopeptidase 23B(Previous name: matrix metalloproteinase 23B )
(Previous symbol: MMP22)
| |
Aliases
for MMP23B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Matrix Metallopeptidase 23B1 2 | | MMP-232 3 | | MMP221 2 3 5 | | MMP23A2 | | MIFR-11 2 3 | | Femalysin3 | | MIFR1 2 | | Matrix Metalloproteinase 222 | | Matrix Metalloproteinase 23B1 2 | | Matrix Metalloproteinase In The Female Reproductive Tract2 | | Matrix Metalloproteinase-212 3 | | Matrix Metalloproteinase-232 | | Matrix Metalloproteinase-222 3 | | EC 3.4.24.-3 | | MMP-212 3 | | Femalysin3 | | MMP-222 3 | | MMP213 |
Export aliases for MMP23B gene to outside databasesPrevious GC identifers: GC01P001188 GC01P001437 GC01P001500 GC01P001580 GC01P9N0048 GC01P001558 GC01P000843 |
Summaries
for MMP23B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MMP23B:
This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated regionof chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown ofextracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissueremodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomericcopy of the duplicated region. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MMP23_HUMAN, O75900Function: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmicreticulum (By similarity)
 summary
for MMP23B: Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent
endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a
wide range of extracellular molecules and a number of bioactive molecules. 24 matrixin genes have been
identified in humans, which can be organized into six groups based on domain organization and substrate
preference: Collagenases (MMP-1, -8 and -13), Gelatinases (MMP-2 and MMP-9), Stromelysins (MMP-3, -10 and
-11), Matrilysin (MMP-7 and MMP-26), Membrane-type (MT)-MMPs (MMP-14, -15, -16, -17, -24 and -25) and others
(MMP-12, -19, -20, -21, -23, -27 and -28). MMP activity is regulated by two major endogenous inhibitors:
alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMPs play a central role in cell
proliferation, migration, differentiation, angiogenesis, apoptosis and host defences. Dysregulatoin of MMPs
has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis and cancer.
Tumour metastasis is a multistep process involving the dessemination of tumor cells from the primary tumor
to secondarys at a distant organ or tissue. One of the first steps in metastasis is the degradation of the
basement membrane, a process in which MMPs have been implicated. MMPs are secreted by tumor cells themselves
or by surrounding stromal cells stimulated by the nearby tumor. Numerous studies have linked altered MMP
expression in different human cancers with poor disease prognosis. MMP-1, -2, -3, -7, -9, -13 and -14 all
have elevated expression in primary tumors and/or metastases. Synthetic or natural inhibitors of MMPs result
in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.
Gene Wiki entry for MMP23B
|
Genomic Views
for MMP23B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NT_004350.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MMP23B gene promoter:
c-Fos AP-1 Tal-1 p53 c-Jun C/EBPalpha Roaz ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for MMP23B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMP23B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.3 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1p36.3MMP23B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P001559: view genomic region
(about GC identifiers)
Start:
|
1,567,474 bp from pter |
End:
|
1,570,639 bp from pter |
Size:
|
3,166 bases |
Orientation:
|
plus strand |
|
Proteins
for MMP23B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MMP23_HUMAN, O75900 (See
protein sequence)Recommended Name: Matrix metalloproteinase-23 precursor Size: 390 amino acids; 43935 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity). Membrane;Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist (Probable)
Secondary accessions: A2AGN0 A2AGN1 O75894 O75895 Q5QPQ8 Q76P96 Q7LDM6 Q7LDM7 Q9UBR9 Q9UJK8Alternative splicing: 3 isoforms: O75900-1 O75900-2 O75900-3 Explore the universe of human proteins at neXtProt for MMP23B: NX_O75900
Post-translational modifications:
N-glycosylated1
Proteolytic cleavage might yield an active form (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75900
MMP23B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008914.1
ENSEMBL proteins: ENSP00000348308 ENSP00000424976 ENSP00000423780 ENSP00000367945 ENSP00000426293 ENSP00000405867 ENSP00000426857 ENSP00000462142
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
MMP23B for ontologies About GeneDecksing
MMP23B Antibody Products:
Assay Products for MMP23B: |
Protein
Domains /
Families
for MMP23B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MMP23B for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry O75900ProtoNet protein and cluster: O75900 2 Blocks protein families: IPB003582 Metridin-like ShK toxin IPB003599 Immunoglobulin subtype
UniProtKB/Swiss-Prot: MMP23_HUMAN, O75900Domain: The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolarrange. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4 (By similarity)Similarity: Belongs to the peptidase M10A familySimilarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain |
Function
for MMP23B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MMP23_HUMAN, O75900Function: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmicreticulum (By similarity)Enzyme regulation: Inhibited by TIMP2 (By similarity) Genatlas biochemistry entry for MMP23B:matrix metalloproteinase 23B,regulator in matrix remodeling,with three alternatively spliced isoforms A,B,C,expressedin ovary,testis,prostate
Enzyme Number (IUBMB): EC 3.4.24.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MMP23B (NM_006983) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MMP23B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP23B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP23B |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
MMP23B for ontologies About GeneDecksing
|
Pathways & Interactions
for MMP23B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Matrix Metalloproteinases | | | 2 | Integrin Pathway | | | 3 | GPCR Pathway | |
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MMP23B
1  BioSystems Pathway for MMP23B
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MMP23B
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for MMP23B (ENSP000003483084) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
MMP23B for ontologies About GeneDecksing
|
Drugs & Compounds
for MMP23B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for MMP23B available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| CP 471474 | Broad spectrum MMP inhibitor | [210755-45-6] | | Marimastat | Broad spectrum MMP inhibitor | [154039-60-8] | | ONO 4817 | Broad spectrum MMP inhibitor | [223472-31-9] | | Batimastat | Potent, broad spectrum MMP inhibitor | [130370-60-4] | | PD 166793 | Broad spectrum MMP inhibitor | [199850-67-4] |
Search CenterWatch for drugs/clinical trials and news about MMP23B / MMP23
|
Transcripts
for MMP23B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MMP23B gene: NM_006983.1 Unigene Cluster for MMP23B: Matrix metallopeptidase 23B Hs.192316 [show with all ESTs]Unigene Representative Sequence: BM80514310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000356026(uc001agp.3) ENST00000472264 ENST00000512731 ENST00000378675(uc001agq.3 uc001agr.3 uc009vki.3)
ENST00000479814 ENST00000435358 ENST00000503792 ENST00000489782 ENST00000486400
ENST00000490017
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MMP23B (NM_006983) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MMP23B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP23B |
Additional cDNA sequence: AB010961.1 AF056200.1 AJ005256.1 AK297700.1 BC025719.1 7 DOTS entries: DT.100778024 DT.452256 DT.121399135 DT.91831762 DT.100662335 DT.100021964 DT.92422118 24/40 AceView cDNA sequences (see all 40): BM679806 BQ575307 BM930943 AF086353 CR608527 BX100332 BX096766 BI517766 AJ707857 BI829304 AF057061 CB048617 BM717784 CF127824 AI815030 BM796874 AF057062 AA151428 BM544158 BI518194 AB010962 AB010961 AI347985 AA626131
GeneLoc Exon Structure
|
Expression
for MMP23B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MMP23B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAGGCTCT
About this image
See MMP23B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MMP23B
SOURCE GeneReport for Unigene cluster: Hs.192316
UniProtKB/Swiss-Prot: MMP23_HUMAN, O75900Tissue specificity: Predominantly expressed in ovary, testis and prostate
SABiosciences Custom PCR Arrays for MMP23B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMP23B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MMP23B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP23B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP23B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP23B |
Orthologs
for MMP23B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MMP23B gene from 6/13 species (see all 13) About this table
ENSEMBL Gene Tree for MMP23B (if available)
TreeFam Gene Tree for MMP23B (if available) |
Paralogs
for MMP23B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MMP23B gene
- MMP212 MMP192 MMP72 MMP262
3 SIMAP similar genes for MMP23B using alignment to 7 protein entries: MMP23_HUMAN (see all proteins):MMP23A mifr-2 MMP1
MMP23B for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for MMP23B
PGOHUM00000251106 PGOHUM00000251107
|
Genomic Variants
for MMP23B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MMP23B (1567474 - 1570639 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for MMP23B
6 CNVs: 2042 2295 63709 30362 74286 3276 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MMP23B |
|
Disorders
/ Diseases
for MMP23B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MMP23B for disorders About GeneDecksing
OMIM gene information: 603321
OMIM disorders: --
10  diseases for MMP23B: About MalaCardsencephalomyelitis arthritis transient hypogammaglobulinemia choanal atresia
craniosynostosis adenoma prostatitis carcinoma
adenocarcinoma pancreatitis
2 diseases from the University of Copenhagen DISEASES database for MMP23B:Transient hypogammaglobulinemia Choanal atresia Export disorders for MMP23B gene to outside databases
|
Publications
for MMP23B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MMP23B gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with MMP23B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and characterization of two novel metalloproteinase genes linked to the Cdc2L locus on human chromosome 1p36.3. (PubMed id 9740677)1, 2, 3, 9 Gururajan R.... Kidd V.J. (1998)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning and characterization of a rat ortholog of MMP-23 (matrix metalloproteinase-23), a unique type of membrane-anchored matrix metalloproteinase and conditioned switching of its expression during the ovarian follicular development. (PubMed id 11328856)1, 2 Ohnishi J....Takahashi T. (2001)
- Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members. (PubMed id 9988691)1, 2 Velasco G....Lopez-Otin C. (1999)
- Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2. (PubMed id 9750192)1, 3 Gururajan R....Kidd V.J. (1998)
- Delineation of mechanisms and regions of dosage imbalance in complex rearrangements of 1p36 leads to a putative gene for regulation of cranial suture closure. (PubMed id 15483646)1 Gajecka M....Shaffer L.G. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes. (PubMed id 10949161)1 Terp G.E....Jorgensen F.S. (2000)
- Matrix metalloproteinases. (PubMed id 10419448)1 Nagase H. and Woessner J.F. (1999)
|
External Searches for MMP23B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MMP23B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MMP23B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MMP23B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MMP23B gene:
Search GeneIP for patents involving MMP23B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MMP23B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MMP23B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MMP23B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMP23B | | | OriGene Protein Over-expression Lysate for MMP23B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MMP23B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMP23B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MMP23B | | OriGene Custom Protein Services for MMP23B | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MMP23B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MMP23B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMP23B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMP23B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP23B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP23B |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | MMP23B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP23B |
|  |  |  | | | | ThermoFisher Antibodies for MMP23B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP23B |
|
|
|
|
