Aliases for MMP23B Gene
External Ids for MMP23B Gene
Previous HGNC Symbols for MMP23B Gene
Previous GeneCards Identifiers for MMP23B Gene
This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]
GeneCards Summary for MMP23B Gene
MMP23B (Matrix Metallopeptidase 23B) is a Protein Coding gene. Diseases associated with MMP23B include Chromosome 1P36 Deletion Syndrome. Among its related pathways are GPCR Pathway and Integrin Pathway. GO annotations related to this gene include metalloendopeptidase activity and metallopeptidase activity. An important paralog of this gene is MMP19.
UniProtKB/Swiss-Prot for MMP23B Gene
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent endopeptidases and the major proteases in ECM degradation. MMPs are capable of degrading several extracellular molecules and a number of bioactive molecules.