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MMP10 Gene

protein-coding   GIFtS: 72
GCID: GC11M102641

Matrix Metallopeptidase 10 (Stromelysin 2)

(Previous name: matrix metalloproteinase 10 (stromelysin 2))
(Previous symbol: STMY2)
Microbiology & Infectious Diseases Congress
  See related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Matrix Metallopeptidase 10 (Stromelysin 2)1 2     Stromelysin 22
STMY21 2 3 5     stromelysin-22
Matrix Metalloproteinase 10 (Stromelysin 2)1 2     Transin 22
Matrix Metalloproteinase-102 3     transin-22
MMP-102 3     EC
SL-22 3     Transin-23
Matrix Metalloprotease 102     EC 3.4.248

External Ids:    HGNC: 71561   Entrez Gene: 43192   Ensembl: ENSG000001666707   OMIM: 1852605   UniProtKB: P092383   

Export aliases for MMP10 gene to outside databases

Previous GC identifers: GC11M104834 GC11M103998 GC11M102675 GC11M102178 GC11M102146 GC11M098569

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MMP10 Gene:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in
normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in
disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are
activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and
fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. (provided by
RefSeq, Jul 2008)

GeneCards Summary for MMP10 Gene: 
MMP10 (matrix metallopeptidase 10 (stromelysin 2)) is a protein-coding gene. Diseases associated with MMP10 include mast cell neoplasm, and refractive error, and among its related super-pathways are Inhibition of Matrix Metalloproteinases and Metalloproteases in connective tissue degradation. GO annotations related to this gene include metalloendopeptidase activity and calcium ion binding. An important paralog of this gene is MMP20.

UniProtKB/Swiss-Prot: MMP10_HUMAN, P09238
Function: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates

summary for MMP10 Gene:
Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent
endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a
wide range of extracellular molecules and a number of bioactive molecules. 24 matrixin genes have been
identified in humans, which can be organized into six groups based on domain organization and substrate
preference: Collagenases (MMP-1, -8 and -13), Gelatinases (MMP-2 and MMP-9), Stromelysins (MMP-3, -10 and
-11), Matrilysin (MMP-7 and MMP-26), Membrane-type (MT)-MMPs (MMP-14, -15, -16, -17, -24 and -25) and others
(MMP-12, -19, -20, -21, -23, -27 and -28). MMP activity is regulated by two major endogenous inhibitors:
alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMPs play a central role in cell
proliferation, migration, differentiation, angiogenesis, apoptosis and host defences. Dysregulatoin of MMPs
has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis and cancer.
Tumour metastasis is a multistep process involving the dessemination of tumor cells from the primary tumor
to secondarys at a distant organ or tissue. One of the first steps in metastasis is the degradation of the
basement membrane, a process in which MMPs have been implicated. MMPs are secreted by tumor cells themselves
or by surrounding stromal cells stimulated by the nearby tumor. Numerous studies have linked altered MMP
expression in different human cancers with poor disease prognosis. MMP-1, -2, -3, -7, -9, -13 and -14 all
have elevated expression in primary tumors and/or metastases. Synthetic or natural inhibitors of MMPs result
in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.

Gene Wiki entry for MMP10 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MMP10 gene promoter:
         CREB   SRF   AP-1   deltaCREB   ATF-2   SRF (504 AA)   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMMP10 promoter sequence
   Search SABiosciences Chromatin IP Primers for MMP10

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMP10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q22.3   Ensembl cytogenetic band:  11q22.2   HGNC cytogenetic band: 11q22.3

MMP10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MMP10 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M102641:  view genomic region     (about GC identifiers)

102,641,233 bp from pter      End:
102,651,359 bp from pter
10,127 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MMP10_HUMAN, P09238 (See protein sequence)
Recommended Name: Stromelysin-2 precursor  
Size: 476 amino acids; 54151 Da
Cofactor: Binds 2 zinc ions per subunit
Cofactor: Calcium
Subcellular location: Secreted, extracellular space, extracellular matrix (Probable)
2 PDB 3D structures from and Proteopedia for MMP10:
1Q3A (3D)        3V96 (3D)    
Secondary accessions: B2R9X9 Q53HH9

Explore the universe of human proteins at neXtProt for MMP10: NX_P09238

Explore proteomics data for MMP10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P09238

  • 4/12 DME Specific Peptides for MMP10 (P09238) (see all 12)

    MMP10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MMP10 Protein Expression
    REFSEQ proteins: NP_002416.1  
    ENSEMBL proteins: 
     ENSP00000279441   ENSP00000441485  
    Reactome Protein details: P09238
    Human Recombinant Protein Products for MMP10: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for MMP10 (MMP-10)
    Enzo Life Sciences proteins for MMP10
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for MMP10
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MMP10
    GenScript Custom Purified and Recombinant Proteins Services for MMP10
    Novus Biologicals MMP10 Proteins
    Novus Biologicals MMP10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MMP10 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005615extracellular space TAS2844164
    GO:0031012extracellular matrix ----

    MMP10 for ontologies           About GeneDecksing

    MMP10 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for MMP10 (MMP-10)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MMP10
    GenScript Custom Superior Antibodies Services for MMP10
    Novus Biologicals MMP10 Antibodies
    Abcam antibodies for MMP10
    Cloud-Clone Corp. Antibodies for MMP10 
    ThermoFisher Antibody for MMP10
    LSBio Antibodies in human, mouse, rat for MMP10 

    Assay Products for MMP10: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MMP10
    R&D Systems ELISAs for MMP10 (MMP-10)         (see all)
    GenScript MMP10-Activity-based Protease Assay for Compound Screening
    Enzo Life Sciences assays for MMP10
    Cloud-Clone Corp. ELISAs for MMP10 
    Cloud-Clone Corp. CLIAs for MMP10

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: MMP10 
    Cell-surface protein and extracellular matrix metalloproteinases

    5/10 InterPro protein domains (see all 10):
     IPR024079 MetalloPept_cat_dom
     IPR021158 Pept_M10A_Zn_BS
     IPR021190 Pept_M10A
     IPR000585 Hemopexin-like_dom
     IPR018486 Hemopexin_CS

    Graphical View of Domain Structure for InterPro Entry P09238

    ProtoNet protein and cluster: P09238

    3 Blocks protein domains:
    IPB000585 Hemopexin repeat
    IPB001818 Matrixin
    IPB002477 Putative peptidoglycan binding domain 1

    UniProtKB/Swiss-Prot: MMP10_HUMAN, P09238
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting
    the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the
    Similarity: Belongs to the peptidase M10A family
    Similarity: Contains 4 hemopexin repeats

    MMP10 for domains           About GeneDecksing

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MMP10_HUMAN, P09238
    Function: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates
    Catalytic activity: Similar to stromelysin 1, but action on collagen types III, IV and V is weak

         Genatlas biochemistry entry for MMP10:
    matrix metalloproteinase 10,regulator in matrix remodeling in the MMP cluster,expressed in the developing bone

         Enzyme Numbers (IUBMB): EC 3.4.242 EC

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004222metalloendopeptidase activity IEA--
    GO:0005509calcium ion binding IEA--
    GO:0008237metallopeptidase activity ----
    GO:0008270zinc ion binding IEA--
    MMP10 for ontologies           About GeneDecksing

         1 GenomeRNAi human phenotype for MMP10:
     Proliferating cells 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Mmp10):
     cardiovascular system  immune system  normal  respiratory system 

    MMP10 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for MMP10: Mmp10tm1Jkmg Mmp10tm1Lex

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MMP10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MMP10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MMP10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MMP10 

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MMP10
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MMP10:
    SwitchGear 3'UTR luciferase reporter plasmidMMP10 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MMP10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMP10

    Gene Editing
    DNA2.0 Custom Protein Engineering Service for MMP10
    Sirion Biotech Customized adenovirus for overexpression of MMP10

    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MMP10 (see all 7)
    OriGene ORF clones in mouse, rat for MMP10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MMP10 (NM_002425)
    Sino Biological Human cDNA Clone for MMP10
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MMP10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP10
    Sirion Biotech Customized lentivirus for stable overexpression of MMP10 
                         Customized lentivirus expression plasmids for stable overexpression of MMP10 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for MMP10
    LifeMap BioReagents: cell line associated with MMP10: PureStem 7SMOO32, NCr-fac & Meso Progenitor
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP10

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MMP10 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Matrix Metalloproteinases
    Matrix Metalloproteinases0.68
    Inhibition of Matrix Metalloproteinases0.68
    2Cell adhesion ECM remodeling
    Cell adhesion ECM remodeling0.31
    Metalloproteases in connective tissue degradation0.31
    3Degradation of the extracellular matrix
    Degradation of the extracellular matrix0.79
    Activation of Matrix Metalloproteinases0.40
    Degradation of collagen0.79
    4Integrin Pathway
    UPA-UPAR Pathway0.56
    Transendothelial Migration of Leukocytes0.38
    5GPCR Pathway
    Pancreatic Adenocarcinoma0.59

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for MMP10
        Cell adhesion ECM remodeling
    Metalloproteases in connective tissue degradation

    4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MMP10
        Inhibition of Matrix Metalloproteinases
    Transendothelial Migration of Leukocytes
    UPA-UPAR Pathway
    Pancreatic Adenocarcinoma

    1 GeneGo (Thomson Reuters) Pathway for MMP10
        Cell adhesion ECM remodeling

    1 BioSystems Pathway for MMP10
        Matrix Metalloproteinases

    4        Reactome Pathways for MMP10
        Extracellular matrix organization
    Degradation of the extracellular matrix
    Degradation of collagen
    Activation of Matrix Metalloproteinases

    MMP10 for pathways           About GeneDecksing


        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MMP10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for MMP10 (P092383 ENSP000002794414) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HAPLN1P109153, ENSP000002743414I2D: score=1 STRING: ENSP00000274341
    MMP9P147803, ENSP000003614054I2D: score=1 STRING: ENSP00000361405
    BCANQ96GW73, ENSP000003312104I2D: score=2 STRING: ENSP00000331210
    MMP1ENSP000003227884STRING: ENSP00000322788
    MMP2ENSP000002190704STRING: ENSP00000219070
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0022617extracellular matrix disassembly TAS--
    GO:0030198extracellular matrix organization TAS--
    GO:0030334regulation of cell migration IEA--
    GO:0030574collagen catabolic process TAS--

    MMP10 for ontologies           About GeneDecksing

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MMP10 for compounds           About GeneDecksing

    EMD Millipore small molecules for MMP10:
    Small Molecule - inhibitor
    Enzo Life Sciences drugs & compounds for MMP10

    Compounds for MMP10 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    GI 254023XSelective ADAM10 metalloprotease inhibitor[260264-93-5]
    MarimastatBroad spectrum MMP inhibitor[154039-60-8]
    GM 6001Broad-spectrum MMP inhibitor[142880-36-2]
    UK 383367Potent and selective BMP-1 (PCP) inhibitor[348622-88-8]
    Batimastat Potent, broad spectrum MMP inhibitor [130370-60-4]

    1 HMDB Compound for MMP10    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    2 DrugBank Compounds for MMP10    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Marimastat-- 154039-60-8targetantagonist10852638 10669951

    7 Novoseek inferred chemical compound relationships for MMP10 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    (4-aminophenyl)mercuric acetate 74.2 1 9578462 (1)
    matrigel 22.8 1 12379519 (1)
    12-o-tetradecanoylphorbol 13-acetate 9.97 1 8144618 (1)
    serine 8.4 6 15870107 (3), 19762781 (1), 16983356 (1), 17069010 (1)
    vegf 4.55 3 15868281 (1), 16980307 (1), 19220217 (1)
    oligonucleotide 0 2 8269280 (1), 9550265 (1)
    calcium 0 2 19769250 (1)

    Search CenterWatch for drugs/clinical trials and news about MMP10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MMP10 gene: 

    Unigene Cluster for MMP10:

    Matrix metallopeptidase 10 (stromelysin 2)
    Hs.2258  [show with all ESTs]
    Unigene Representative Sequence: NM_002425
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000279441(uc001phg.2) ENST00000539681
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MMP10
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MMP10:
    SwitchGear 3'UTR luciferase reporter plasmidMMP10 3' UTR sequence
    Inhib. RNA
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MMP10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMP10
    OriGene clones in human, mouse for MMP10 (see all 7)
    OriGene ORF clones in mouse, rat for MMP10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MMP10 (NM_002425)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MMP10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMP10
    Sirion Biotech Customized lentivirus for stable overexpression of MMP10 
                         Customized lentivirus expression plasmids for stable overexpression of MMP10 
    OriGene qPCR primer pairs and template standards for MMP10
    OriGene qSTAR qPCR primer pairs in human, mouse for MMP10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MMP10
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP10

    Additional mRNA sequence: 

    AK222601.1 AK313960.1 BC002591.2 BT007442.1 X07820.1 

    5 DOTS entries:

    DT.106379  DT.120702938  DT.120702949  DT.99929471  DT.313463 

    24/56 AceView cDNA sequences (see all 56):

    BX281044 BP350564 BP351322 X07820 BC002591 NM_002425 BP351309 AI973162 
    BP351427 BP352259 BP352568 BP350592 BP352531 BE740153 BP351724 AW949366 
    BT007442 BP351604 BP351299 AW296143 BP351055 CF596568 BM555652 BP351598 

    GeneLoc Exon Structure

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MMP10 expression in normal human tissues (normalized intensities)      MMP10 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MMP10 Expression
    About this image

    MMP10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/17 selected tissues (see all 17) fully expand
     Endothelium (Cardiovascular System)    fully expand to see all 6 entries
             PureStem endothelial progenitor 30-SM2-1
             Human Umbilical Artery Endothelial Cells (HUAEC)   
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 3 entries
             Wharton's jelly-derived stem cells
             Human Umbilical Artery Endothelial Cells (HUAEC)   
     Intestine (Gastrointestinal Tract)    fully expand to see all 2 entries
             SMALL INTESTINE   
     Uterus (Reproductive System)
             Uterus Corpus   
     Mesoderm (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor

    See MMP10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MMP10

    SOURCE GeneReport for Unigene cluster: Hs.2258
        SABiosciences Expression via Pathway-Focused PCR Arrays including MMP10: 
              Osteogenesis in human mouse rat
              Extracellular Matrix & Adhesion Molecules in human mouse rat
              Tumor Metastasis in human mouse rat

    OriGene qPCR primer pairs and template standards for MMP10
    OriGene qSTAR qPCR primer pairs in human, mouse for MMP10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MMP10
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMP10
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMP10
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMP10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MMP10 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Mmp101 , 5 matrix metallopeptidase 101, 5 80.35(n)1
      9 (2.46 cM)5
    173841  NM_019471.21  NP_062344.11 
    (Gallus gallus)
    Aves MMP101 matrix metallopeptidase 10 (stromelysin 2) 62.55(n)
      418981  XM_417175.2  XP_417175.1 
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    many ↔ many
    many ↔ many
    (Danio rerio)
    Actinopterygii mmp301 matrix metallopeptidase 30 53.12(n)
      678531  NM_001040291.1  NP_001035381.1 

    ENSEMBL Gene Tree for MMP10 (if available)
    TreeFam Gene Tree for MMP10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68)
    About This Section
    Paralogs for MMP10 gene
    MMP202  MMP132  MMP82  MMP142  MMP252  MMP162  MMP72  MMP242  
    MMP152  MMP32  MMP272  MMP112  MMP172  MMP12  
    18 SIMAP similar genes for MMP10 using alignment to 2 protein entries:     MMP10_HUMAN (see all proteins):
    MMP3    MMP1    MMP13    MMP12    MMP27    MMP8
    MMP20    MMP7    MMP2    MMP26    MMP17    MMP14
    MMP11    MMP16    MMP19    MMP24    MMP25    MMP15

    MMP10 for paralogs           About GeneDecksing

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/386 SNPs in MMP10 are shown (see all 386)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 11 posSequence#AA
    A breast cancer sample4--see VAR_0361392 E Q mis40--------
    --102640800(+) TGAGGC/GGGAGA 1 -- ds50010--------
    C,F,A,H--102640805(+) GGGAGA/CTGAGA 1 -- ds500119Minor allele frequency- C:0.44NS EA NA WA 1416
    C,F--102640838(-) GTGGGA/TTTCCT 1 -- ds50018Minor allele frequency- T:0.12NS NA CSA 312
    --102640882(+) TGGACA/TCCAAA 1 -- ds50010--------
    C--102640935(+) ATAATA/GTGCAG 1 -- ds50010--------
    C--102640969(-) GAAATG/TGAACT 1 -- ds50011Minor allele frequency- T:0.01NS 180
    --102641024(+) TTACCC/TCTTTC 1 -- ds50010--------
    F--102641042(+) GGTGTG/ATAAGG 1 -- ds50011Minor allele frequency- A:0.01WA 118
    --102641061(+) CAATAA/TCTGTG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for MMP10 (102641233 - 102651359 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MMP10:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv463CNV Insertion18451855

    Human Gene Mutation Database (HGMD): MMP10
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MMP10
    DNA2.0 Custom Variant and Variant Library Synthesis for MMP10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 185260    OMIM disorders: --

    20/59 diseases for MMP10 (see all 59):    About MalaCards
    mast cell neoplasm    refractive error    epidermolysis bullosa dystrophica    vernal keratoconjunctivitis
    encephalomyelitis    keratoconus    pyoderma    pyoderma gangrenosum
    skin cancer    bladder transitional cell carcinoma    transitional cell carcinoma    keratoacanthoma
    arthritis    gingival overgrowth    squamous cell carcinoma of the head and neck    abdominal aortic aneurysm
    gastric adenocarcinoma    keratoconjunctivitis    epidermolysis bullosa    gingivitis

    2 diseases from the University of Copenhagen DISEASES database for MMP10:
    Lymphoma     Mast cell neoplasm

    MMP10 for disorders           About GeneDecksing

    10/24 Novoseek inferred disease relationships for MMP10 gene (see all 24)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    invasive cancer 48.3 1 19601983 (1)
    squamous cell cancer 47.3 2 19601983 (1)
    hnscc 43.4 1 16265652 (1)
    carcinoma squamous cell 42.6 7 12269770 (2), 17587817 (1), 14977049 (1), 11237387 (1)
    tumors 38.3 61 15833553 (5), 17695449 (4), 15720804 (3), 15356104 (2) (see all 20)
    metastasis 37 5 11487270 (1), 15557792 (1), 19921252 (1), 17695449 (1) (see all 5)
    keratoconus 37 1 11778801 (1)
    venous ulcer 34.3 3 11069614 (2), 8776359 (1)
    skin cancer 25.5 3 19601983 (1), 11237387 (1)
    carcinoma 24.1 7 1655673 (2), 7677979 (1), 1793490 (1), 11237387 (1)

    Genetic Association Database (GAD): MMP10
    Human Genome Epidemiology (HuGE) Navigator: MMP10 (12 documents)

    Export disorders for MMP10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MMP10 gene, integrated from 9 sources (see all 203) (see top 10):
    (articles sorted by number of sources associating them with MMP10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure of the catalytic domain of human matrix metalloproteinase 10. (PubMed id 15095982)1, 2, 9 Bertini I....Terni B. (2004)
    2. Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. (PubMed id 15944607)1, 4, 9 Ogata T....Kuivaniemi H. (2005)
    3. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    4. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    5. Interferon gamma receptor 2 gene variants are associa ted with liver fibrosis in patients with chronic hepatitis C infection. (PubMed id 20587546)1, 4 Nalpas B....Abel L. (2010)
    6. Identification of fetal and maternal single nucleotid e polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1, 4 Romero R....Menon R. (2010)
    7. A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1, 4 Romero R....Menon R. (2010)
    8. Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease. (PubMed id 18035073)1, 4 Hlatky M.A....Go A.S. (2007)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. The collagenase gene family in humans consists of at least four members. (PubMed id 2844164)1, 2 Muller D....Breathnach R. (1988)
    11. Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis. (PubMed id 17009259)1, 9 Barksby H.E....Rowan A.D. (2006)
    12. Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral di sc. (PubMed id 19695094)1, 9 Richardson S.M....Hoyland J.A. (2009)
    13. Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer. (PubMed id 18427549)1, 9 Frederick L.A....Fields A.P. (2008)
    14. Expression of MMP-10 in lung cancer. (PubMed id 17695449)1, 9 Zhang X....Xu N. (2007)
    15. Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbolesters. (PubMed id 8349617)1, 9 Windsor L.J....Birkedal-Hansen H. (1993)
    16. Matrix metalloproteinase-10 is upregulated by thrombi n in endothelial cells and increased in patients with enhanced thrombin generat ion. (PubMed id 19762781)1, 9 Orbe J....PA!ramo J.A. (2009)
    17. Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer. (PubMed id 16331256)1, 9 Aung P.P....Yasui W. (2006)
    18. Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases. (PubMed id 9578462)1, 9 Nakamura H....Okada Y. (1998)
    19. MMP-10 (Stromelysin-2) and MMP-21 in human and murine squamous cell cancer. (PubMed id 19601983)1, 9 Boyd S....Saarialho-Kere U. (2009)
    20. Transcriptional induction of MMP-10 by TGF-beta, medi ated by activation of MEF2A and downregulation of class IIa HDACs. (PubMed id 19935709)1, 9 Ishikawa F....Shibanuma M. (2010)
    21. Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in M erkel cell carcinoma. (PubMed id 19921252)1, 9 Suomela S....Saarialho-Kere U. (2009)
    22. Stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) expression in developing human bone: potential roles in skeletal development. (PubMed id 9662124)1, 9 Bord S....Compston J.E. (1998)
    23. Activation of human neutrophil procollagenase by stromelysin 2. (PubMed id 8631328)1, 9 Knauper V....Tschesche H. (1996)
    24. Vascular MMP-9/TIMP-2 and neuronal MMP-10 up-regulati on in human brain after stroke: a combined laser microdissection and protein ar ray study. (PubMed id 19317417)1, 9 Cuadrado E....Montaner J. (2009)
    25. C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis. (PubMed id 16580524)1, 9 Montero I....Paramo J.A. (2006)
    26. Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10. (PubMed id 16054593)1, 9 Schnabl B....Scholmerich J. (2005)
    27. cDNA cloning and expression of the gene encoding murine stromelysin-2 (MMP-10). (PubMed id 9427548)1, 9 Madlener M. and Werner S. (1997)
    28. Expression pattern of matrix metalloproteinases in human liver. (PubMed id 7632822)1, 9 Lichtinghagen R....Boker K.H. (1995)
    29. Beta-carotene inhibits UVA-induced matrix metalloprotease 1 and 10 expression in keratinocytes by a singlet oxygen-dependent mechanism. (PubMed id 15288123)1, 9 Wertz K....Goralczyk R. (2004)
    30. Phenotypic alterations in fos-transgenic mice correlate with changes in Fos/Jun-dependent collagenase type I expression. Regulation of mouse metalloproteinases by carcinogens, tumor promoters, cAMP, and Fos oncoprotein. (PubMed id 8144618)1, 9 Gack S....Angel P. (1994)
    31. Stromelysins in placental membranes and amniotic fluid with premature rupture of membranes. (PubMed id 10472874)1, 9 Fortunato S.J....Lombardi S.J. (1999)
    32. Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein. (PubMed id 7694569)1, 9 Nguyen Q....Roughley P.J. (1993)
    33. Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins. (PubMed id 1874716)1, 9 Fosang A.J....Hamilton J.A. (1991)
    34. Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization. (PubMed id 2369069)1, 9 Jung J.Y....Rumpler Y. (1990)
    35. The role of DNA hypomethylation in the control of stromelysin gene expression. (PubMed id 16516860)1, 9 Couillard J....St-Pierre Y. (2006)
    36. A genome-wide association study of brain lesion distri bution in multiple sclerosis. (PubMed id 23412934)1 Gourraud P.A....Baranzini S.E. (2013)
    37. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)
    38. C-terminal truncated hepatitis B virus x protein is as sociated with metastasis and enhances invasiveness by C-Jun/matrix metalloprotei nase protein 10 activation in hepatocellular carcinoma. (PubMed id 22821423)1 Sze K.M....Ng I.O. (2013)
    39. Matrix metalloproteinases and educational attainment i n refractive error: evidence of gene-environment interactions in the Age-Related Eye Disease Study. (PubMed id 23098370)1 Wojciechowski R....Stambolian D. (2013)
    40. Application of MMP-7 and MMP-10 in assisting the diagn osis of malignant pleural effusion. (PubMed id 22524815)1 Cheng D....Li Y.H. (2012)
    41. Overexpression of matrix metalloproteinase 10 is assoc iated with poor survival in patients with early stage of esophageal squamous cel l carcinoma. (PubMed id 22121946)1 Liu H....Guan X.Y. (2012)
    42. Synergistic effect of thrombin and CD40 ligand on endo thelial matrix metalloproteinase-10 expression and microparticle generation in v itro and in vivo. (PubMed id 22492089)1 Martinez de Lizarrondo S....Orbe J. (2012)
    43. Matrix metalloproteinase-10 is required for lung cance r stem cell maintenance, tumor initiation and metastatic potential. (PubMed id 22545096)1 Justilien V....Fields A.P. (2012)
    44. Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and c rystal structure. (PubMed id 22427646)1 Batra J....Radisky E.S. (2012)
    45. Genetic variations in matrix metalloproteinases may b e associated with increased risk of ulcerative colitis. (PubMed id 21925226)1 Morgan A.R....Ferguson L.R. (2011)
    46. Type-specific dysregulation of matrix metalloproteina ses and their tissue inhibitors in end-stage heart failure patients: relationsh ip between MMP-10 and LV remodelling. (PubMed id 20219015)1 Wei Y....Hu S. (2011)
    47. Age- and gender-dependent changes in connective tissu e remodeling: physiological differences in circulating MMP-3, MMP-10, TIMP-1 an d TIMP-2 level. (PubMed id 20215736)1 Komosinska-Vassev K....Olczyk K. (2011)
    48. Matrix metalloproteinase-10 promotes Kras-mediated br onchio-alveolar stem cell expansion and lung cancer formation. (PubMed id 22022614)1 Regala R.P....Fields A.P. (2011)
    49. A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. (PubMed id 21121903)4 Rasi S....Rossi D. (2011)
    50. MMP-10/stromelysin-2 promotes invasion of head and ne ck cancer. (PubMed id 21998657)1 Deraz E.M....Takata T. (2011)
    51. Matrix metalloproteinase-10 effectively reduces infar ct size in experimental stroke by enhancing fibrinolysis via a thrombin-activat able fibrinolysis inhibitor-mediated mechanism. (PubMed id 22104553)1 Orbe J....PA!ramo J.A. (2011)
    52. Immunohistochemical and transcriptional expression of matrix metalloproteinases in full-term human umbilical cord and human umbilica l vein endothelial cells. (PubMed id 20936527)1 Mauro A....Gerbino A. (2010)
    53. Nitric oxide-mediated invasion in Barrett's high-grad e dysplasia and adenocarcinoma. (PubMed id 20584750)1 Clemons N.J....Fitzgerald R.C. (2010)
    54. Association of matrix metalloproteinase gene polymorp hisms with refractive error in Amish and Ashkenazi families. (PubMed id 20484597)1 Wojciechowski R....Stambolian D. (2010)
    55. Expression profiling of ETS and MMP factors in VEGF-a ctivated endothelial cells: role of MMP-10 in VEGF-induced angiogenesis. (PubMed id 20432469)1 Heo S.H....Cho J.Y. (2010)
    56. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    57. Matrix metalloproteinases (MMP) 1 and MMP10 but not M MP12 are potential oral cancer markers. (PubMed id 19489686)1 Yen C.Y....Chang H.W. (2009)
    58. VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis. (PubMed id 18617643)1 Ha C.H....Jin Z.G. (2008)
    59. Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma. (PubMed id 17543340)1 Asano T....Kondo S. (2008)
    60. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    61. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    62. Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. (PubMed id 15371548)1 Krampert M....Werner S. (2004)
    63. Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer. (PubMed id 15375490)1 Lin T.S....Chow K.C. (2004)
    64. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    65. Clinical potential of matrix metalloprotease inhibito rs in cancer therapy. (PubMed id 10852638)7 Heath E.I. and Grochow L.B. (2000)
    66. Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites. (PubMed id 10986281)1 Nakamura H....Okada Y. (2000)
    67. The Protein Data Bank. (PubMed id 10592235)7 Berman H.M....Bourne P.E. (2000)
    68. Matrix metalloproteinases. (PubMed id 10419448)1 Nagase H. and Woessner J.F. (1999)
    69. MMP inhibitors: experimental and clinical studies. (PubMed id 10669951)7 Belotti D....Giavazzi R. (1999)
    70. Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview. (PubMed id 9042108)1 Chandler S....Gearing A.J. (1997)
    71. Activation of type IV procollagenases by human tumor-associated trypsin-2. (PubMed id 9261109)1 Sorsa T....Stenman U.H. (1997)
    72. Fine physical mapping of the human matrix metalloproteinase genes clustered on chromosome 11q22.3. (PubMed id 8921407)1 Pendas A.M....Lopez-Otin C. (1996)
    73. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
    74. Human T lymphocytes express a member of the Matrix Metalloproteinase gene family. (PubMed id 8003069)1 Conca W. and Willmroth F. (1994)
    75. Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. (PubMed id 2605216)1 Sirum K.L. and Brinckerhoff C.E. (1989)
    76. IL-6 regulates MMP-10 expression via JAK2/STAT3 signa ling pathway in a human lung adenocarcinoma cell line. (PubMed id 20032397)9 Zhang X....Xu N. (2009)
    77. Expression of matrix metalloproteinase-10 in human bladder transitional cell carcinoma. (PubMed id 15833553)9 Seargent J.M....Gill J.H. (2005)
    78. Stromelysin-2 (matrix metalloproteinase 10) is inducible in lymphoma cells and accelerates the growth of lymphoid tumors in vivo. (PubMed id 15356104)9 Van Themsche C....St-Pierre Y. (2004)
    79. MMP-10 is overexpressed, proteolytically active, and a potential target for therapeutic intervention in human lung carcinomas. (PubMed id 15720804)9 Gill J.H....Loadman P.M. (2004)
    80. Metalloproteinases and atherothrombosis: MMP-10 mediates vascular remodeling promoted by inflammatory stimuli. (PubMed id 17981764)9 Rodriguez J.A....Paramo J.A. (2008)
    81. Independent association of matrix metalloproteinase-10, cardiovascular risk factors and subclinical atherosclerosis. (PubMed id 17059420)9 Orbe J....Paramo J.A. (2007)
    82. Expression of matrix metalloproteinase-10 in renal cell carcinoma and its prognostic role. (PubMed id 17207914)9 Miyata Y....Kanetake H. (2007)
    83. Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing. (PubMed id 15545168)9 Salmela M.T....Saarialho-Kere U. (2004)
    84. Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers. (PubMed id 11237387)9 Kerkela E....Saarialho-Kere U. (2001)
    85. Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins. (PubMed id 8463259)9 Sanchez-Lopez R....Werb Z. (1993)
    86. Celecoxib inhibits serum amyloid a-induced matrix metalloproteinase-10 expression in human endothelial cells. (PubMed id 18552508)9 Zhao Y....Heng C.K. (2009)
    87. Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines. (PubMed id 11069614)9 Rechardt O....Saarialho-Kere U. (2000)
    88. [The effect of Nifedipine and mechanical strain on ma trix metalloproteinase expression in human periodontal ligament fibroblast] (PubMed id 19769250)9 Ni H....Sun M. (2009)
    89. Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mort ality in sepsis. (PubMed id 19799791)9 Lorente L....PA!ramo J.A. (2009)
    90. Expression of stromelysin and stromelysin-2 in rabbit and human fibroblasts. (PubMed id 1480018)9 Brinckerhoff C.E....Auble D.T. (1992)
    91. Adenovirus-driven overexpression of proteinases in or gan-cultured normal human corneas leads to diabetic-like changes. (PubMed id 19828126)9 Saghizadeh M....Ljubimov A.V. (2010)
    92. Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through mod ulation of MMP-10 expression. (PubMed id 19682763)9 Tomomatsu T....Akagi Y. (2009)
    93. Elevated gene expression of MMP-1, MMP-10, and TIMP-1 reveal changes of molecules involved in turn-over of extracellular matrix in cyclosporine-induced gingival overgrowth. (PubMed id 16670920)9 Dannewitz B....Steinberg T. (2006)
    94. Induction of matrix metalloproteinase gene expression in an endothelial cell line by direct interaction with malignant cells. (PubMed id 17054435)9 Hasebe Y....Nose K. (2007)
    95. Disturbances of the expression of metalloproteinases and their tissue inhibitors cause destruction of the basement membrane in pemphigoid. (PubMed id 17019968)9 Narbutt J....Zebrowska A. (2006)
    96. MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. (PubMed id 15870107)9 Saunders W.B....Davis G.E. (2005)
    97. MMP expression profiling in recurred stage IB lung cancer. (PubMed id 14647437)9 Cho N.H....Cho S.H. (2004)
    98. Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation. (PubMed id 14977049)9 Ramos M.C....Brenneisen P. (2004)
    99. Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas. (PubMed id 14666700)9 Thorns V....Thorns C. (2003)
    100. Human diabetic corneas preserve wound healing, basement membrane, integrin and MMP-10 differences from normal corneas in organ culture. (PubMed id 12873452)9 Kabosova A....Ljubimov A.V. (2003)
    101. Exclusion of stromelysin-1, stromelysin-2, interstitial collagenase and fibronectin genes as the mutant loci in a family with recessive epidermolysis bullosa dystrophica and a form of cerebellar ataxia. (PubMed id 1353052)9 Colombi M....Barlati S. (1992)
    102. Regulation of extracellular matrix remodeling following transforming growth factor-beta1/epidermal growth factor-stimulated epithelial-mesenchymal transition in human premalignant keratinocytes. (PubMed id 17587817)9 Wilkins-Port C.E. and Higgins P.J. (2007)
    103. Stromelysin-2 overexpression in human esophageal squamous cell carcinoma: potential clinical implications. (PubMed id 12269770)9 Mathew R....Ralhan R. (2002)
    104. Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10. (PubMed id 12379519)9 Tolboom T.C....Huizinga T.W. (2002)
    105. Overexpression of matrix metalloproteinase-10 and matrix metalloproteinase-3 in human diabetic corneas: a possible mechanism of basement membrane and integrin alterations. (PubMed id 11159210)9 Saghizadeh M....Ljubimov A.V. (2001)
    106. 1alpha,25-dihydroxyvitamin D3 inhibits matrix metallo proteinases induced by Mycobacterium tuberculosis infection. (PubMed id 19178594)9 Coussens A....Martineau A.R. (2009)
    107. Matrix metalloproteinases: discrete elevations in ess ential hypertension and hypertensive end-stage renal disease. (PubMed id 19886850)9 Friese R.S....O'Connor D.T. (2009)
    108. Cytokines, matrix metalloproteases, angiogenic and growth factors in tears of normal subjects and vernal keratoconjunctivitis patients. (PubMed id 19220217)9 Leonardi A....Sack R. (2009)
    109. Signal-dependent Regulation of Transcription by Histone Deacetylase 7 Involves Recruitment to Promyelocytic Leukemia Protein Nuclear Bodies. (PubMed id 18463162)9 Gao C....Kao H.Y. (2008)
    110. Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum. (PubMed id 18001410)9 Bister V....Saarialho-Kere U. (2007)
    111. Expression of matrix metalloproteinases 3, 10 and 11 (stromelysins 1, 2 and 3) and matrix metalloproteinase 7 (matrilysin) by cancer cells in non-small cell lung neoplasms. Clinicopathologic studies. (PubMed id 16506596)9 Kren L....Ross J.S. (2006)
    112. Molecular balance of capillary tube formation versus regression in wound repair: role of matrix metalloproteinases and their inhibit ors. (PubMed id 17069010)9 Davis G.E. and Saunders W.B. (2006)
    113. Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers. (PubMed id 9710383)9 Saarialho-Kere U.K. (1998)
    114. Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. (PubMed id 8040294)9 Saarialho-Kere U.K....Welgus H.G. (1994)
    115. The order and orientation of a cluster of metalloproteinase genes, stromelysin 2, collagenase, and stromelysin, together with D11S385, on chromosome 11q22-q23. (PubMed id 8486377)9 Formstone C.J....Taylor A.M. (1993)
    116. Detection of mRNAs encoding collagenase I and stromelysin 2 in carcinomas of the head and neck by in situ hybridization. (PubMed id 1655673)9 Polette M....Birembaut P. (1991)
    117. (PubMed id 16983356)9 
    118. A study of matrix metalloproteinase expression and ac tivity in atopic dermatitis using a novel skin wash sampling assay for function al biomarker analysis. (PubMed id 19804592)9 Harper J.I....Chandler S. (2010)
    119. Effects of ultrafine TiO2 particles on gene expressio n profile in human keratinocytes without illumination: involvement of extracell ular matrix and cell adhesion. (PubMed id 19695317)9 Fujita K....Nakanishi J. (2009)
    120. Expression of activated signal transducer and activat or of transcription 3 predicts poor clinical outcome in gastric adenocarcinoma. (PubMed id 19664131)9 Lee J....Park C.K. (2009)
    121. Clinical and biological significance of CXCR5 express ed by prostate cancer specimens and cell lines. (PubMed id 19610059)9 Singh S....Lillard J.W. (2009)
    122. Polyclonal immunoglobulins (IVIg) induce expression o f MMP-9 in microglia. (PubMed id 19833395)9 Pul R....Stangel M. (2009)
    123. CCAAT enhancer binding protein-beta regulates matrix metalloproteinase-1 expression in interleukin-1beta-stimulated A549 lung carcin oma cells. (PubMed id 19723873)9 Armstrong D.A....Vincenti M.P. (2009)
    124. Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease a fter immunosuppressive treatment correlate with histological score and calprote ctin values. (PubMed id 19652986)9 MAokitalo L....Saarialho-Kere U. (2009)
    125. Gingival transcriptome patterns during induction and resolution of experimental gingivitis in humans. (PubMed id 19961380)9 Offenbacher S....Ho B. (2009)
    126. Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. (PubMed id 19243594)9 Eiseler T....Storz P. (2009)
    127. Matrix metalloproteinases and their inhibitors: promi sing novel biomarkers in severe sepsis? (PubMed id 20017890)9 Hoffmann U....Borggrefe M. (2009)
    128. Association between matrix metalloproteinase-10 concentration and smoking in individuals without cardiovascular disease. (PubMed id 19080965)9 PA!ramo J.A....Orbe J. (2008)
    129. Proto-oncogene ACTR/AIB1 promotes cancer cell invasion by up-regulating specific matrix metalloproteinase expression. (PubMed id 18162290)9 Li L.B....Zou J.X. (2008)
    130. Alterations of extracellular matrix components and proteinases in human corneal buttons with INTACS for post-laser in situ keratomileusis keratectasia and keratoconus. (PubMed id 18520507)9 Maguen E....Ljubimov A.V. (2008)
    131. Extracellular matrix mediates a molecular balance between vascular morphogenesis and regression. (PubMed id 18391785)9 Davis G.E. and Senger D.R. (2008)
    132. Correlations of long-term matrix metalloproteinase localization in human corneas after successful laser-assisted in situ keratomileusis with minor complications at the flap margin. (PubMed id 18268205)9 Fournie P.R....Fini M.E. (2008)
    133. Co-activation of synovial fibroblasts by laminin-111 and transforming growth factor-beta induces expression of matrix metalloproteinases 3 and 10 independently of nuclear factor-kappaB. (PubMed id 17720720)9 Warstat K....Aicher W.K. (2008)
    134. Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls. (PubMed id 18034264)9 Boyd S....Saarialho-Kere U. (2008)
    135. Novel bis-(arylsulfonamide) hydroxamate-based selective MMP inhibitors. (PubMed id 18442906)9 Subramaniam R....Mallik S. (2008)
    136. The carbon monoxide-releasing molecule tricarbonyldichlororuthenium(II) dimer protects human osteoarthritic chondrocytes and cartilage from the catabolic actions of interleukin-1beta. (PubMed id 18195133)9 MegA-as J....Alcaraz M.J. (2008)
    137. No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population. (PubMed id 18768525)9 Qiu W....He F. (2008)
    138. The role of stratifin in fibroblast-keratinocyte interaction. (PubMed id 17646930)9 Medina A....Ghahary A. (2007)
    139. mRNA profiling for body fluid identification by multiplex quantitative RT-PCR. (PubMed id 17868268)9 Juusola J. and Ballantyne J. (2007)
    140. Downstream target genes of the neuropeptide S-NPSR1 pathway. (PubMed id 16926187)9 Vendelin J....Kere J. (2006)
    141. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. (PubMed id 16980307)9 Abid M.R....Aird W.C. (2006)
    142. Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells. (PubMed id 16205632)9 Itoh M....Yoshida K. (2006)
    143. Metalloproteinases and their inhibitors: influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas. (PubMed id 16265652)9 Gorogh T....Maune S. (2006)
    144. Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections. (PubMed id 17129374)9 Kanangat S....Schaberg D. (2006)
    145. Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas. (PubMed id 16699496)9 Kuivanen T.T....Saarialho-Kere U.K. (2006)
    146. Regulation of vascular responses to inflammation: inducible matrix metalloproteinase-3 expression in human microvascular endothelial cells is sensitive to antiinflammatory Boswellia. (PubMed id 16677108)9 Roy S....Sen C.K. (2006)
    147. Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis. (PubMed id 15899818)9 Meyer E....Stamenkovic I. (2005)
    148. Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- and phase-specific differential control in vivo. (PubMed id 16046583)9 Vassilev V....Henriet P. (2005)
    149. Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds. (PubMed id 15840104)9 Impola U....Saarialho-Kere U. (2005)
    150. Metalloproteinase expression by control and telomerase immortalized human endometrial endothelial cells. (PubMed id 15944920)9 Krikun G....Lockwood C.J. (2005)
    151. Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response. (PubMed id 16316467)9 Ritter M....Seither P. (2005)
    152. Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas. (PubMed id 16186340)9 Saghizadeh M....Ljubimov A.V. (2005)
    153. A matrix metalloproteinase protein array reveals a strong relation between MMP-9 and MMP-13 with diffusion-weighted image lesion increase in human stroke. (PubMed id 15947272)9 Rosell A....Montaner J. (2005)
    154. Localization of matrix metalloproteinases, (MMPs) their tissue inhibitors, and vascular endothelial growth factor (VEGF) in growth plates of children and adolescents indicates a role for MMPs in human postnatal growth and skeletal maturation. (PubMed id 15868281)9 Haeusler G....Egerbacher M. (2005)
    155. Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities. (PubMed id 15716237)9 Roebuck M.M....Frostick S.P. (2005)
    156. Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases. (PubMed id 15469875)9 Ljumovic D....Kouroumalis E.A. (2004)
    157. Expression and functional role of CCR9 in prostate cancer cell migration and invasion. (PubMed id 15623660)9 Singh S....Lillard J.W. (2004)
    158. Expression of matrix metalloproteinases and their specific inhibitors in normal and different human thyroid tumor cell lines. (PubMed id 15671765)9 Baldini E....D'Armiento M. (2004)
    159. Matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase mRNA levels are specifically altered in torn rotator cuff tendons. (PubMed id 15262646)9 Lo I.K....Frank C.B. (2004)
    160. Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases. (PubMed id 15564854)9 Xie M....Li Y. (2004)
    161. CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. (PubMed id 15467730)9 Singh S....Lillard J.W. (2004)
    162. Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease. (PubMed id 15082589)9 Kirkegaard T....Brynskov J. (2004)
    163. Temporal and spatial expression of matrix metalloprot einases during wound healing of human corneal tissue. (PubMed id 14609553)9 Daniels J.T....Saarialho-Kere U. (2003)
    164. Effects of HDL3 on the expression of matrix-degrading proteases in human endothelial cells. (PubMed id 12792812)9 Norata G.D....Eriksson P. (2003)
    165. Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. (PubMed id 12235077)9 Salmela M.T....Pender S.L. (2002)
    166. C-erbB receptors in squamous cell carcinomas of the head and neck: clinical significance and correlation with matrix metalloproteinases and vascular endothelial growth factors. (PubMed id 11755824)9 O-charoenrat P....Eccles S.A. (2002)
    167. Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma. (PubMed id 11487270)9 Salmela M.T....Saarialho-Kere U. (2001)
    168. Is the corneal degradation in keratoconus caused by matrix-metalloproteinases? (PubMed id 11778801)9 Collier S.A. (2001)
    169. Expression of matrix metalloproteinases and their inhibitors correlates with invasion and metastasis in squamous cell carcinoma of the head and neck. (PubMed id 11448356)9 O-Charoenrat P....Eccles S.A. (2001)
    170. Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions. (PubMed id 11380613)9 Suomela S....Saarialho-Kere U. (2001)
    171. Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis. (PubMed id 11247893)9 Salmela M.T....Saarialho-Kere U. (2001)
    172. Expression and activity of matrix metalloproteases in human malignant mesothelioma cell lines. (PubMed id 11267973)9 Liu Z....Klominek J. (2001)
    173. Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines. (PubMed id 11561728)9 Kim J.H....Lee S.T. (2001)
    174. Induction of collagenase-3 (MMP-13) in rheumatoid arthritis synovial fibroblasts. (PubMed id 11040455)9 Moore B.A....Windsor L.J. (2000)
    175. MMP and TIMP gene expression in head and neck squamous cell carcinomas and adjacent tissues. (PubMed id 11355270)9 Birkedal-Hansen B....Stetler-Stevenson W.G. (2000)
    176. Messenger ribonucleic acid expression of 16 matrix metalloproteinases in bone-implant interface tissues of loose artificial hip joints. (PubMed id 11033543)9 Takei I....Konttinen Y.T. (2000)
    177. Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion. (PubMed id 10760816)9 O-Charoenrat P....Eccles S. (2000)
    178. High collagenolytic activity in spontaneously highly metastatic variants derived from a human pancreatic cancer cell line (SUIT-2) in nude mice. (PubMed id 11688961)9 Kitamura N....Setoguchi T. (2000)
    179. Tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) distribution in normal and pathological human bone. (PubMed id 10071915)9 Bord S....Compston J.E. (1999)
    180. Differential expression of matrix metalloproteinases in bacterial meningitis. (PubMed id 10430840)9 Kieseier B.C....Hartung H.P. (1999)
    181. Purification of active matrix metalloproteinase catalytic domains and its use for screening of specific stromelysin-3 inhibitors. (PubMed id 10336863)9 Kannan R....Basset P. (1999)
    182. Overview of matrix metalloproteinase expression in cultured human cells. (PubMed id 9550265)9 Giambernardi T.A....Klebe R.J. (1998)
    183. Effect of glucose and heparin on mesangial alpha 1(IV)COLL and MMP-2/TIMP-2 mRNA expression. (PubMed id 9075122)9 Caenazzo C....Gambaro G. (1997)
    184. Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds. (PubMed id 8776359)9 Vaalamo M....Saarialho-Kere U.K. (1996)
    185. Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. (PubMed id 8686751)9 Heppner K.J....Rodgers W.H. (1996)
    186. mRNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in interface tissue around implants in loosening total hip arthroplasty. (PubMed id 8953151)9 Ishiguro N....Iwata H. (1996)
    187. The human collagenase-3 (CLG3) gene is located on chromosome 11q22.3 clustered to other members of the matrix metalloproteinase gene family. (PubMed id 7607691)9 Pendas A.M....Lopez-Otin C. (1995)
    188. Neutrophil procollagenase can be activated by stromel ysin-2. (PubMed id 7978810)9 KnAouper V....Tschesche H. (1994)
    189. Metalloproteinase and TIMP expression by the human breast carcinoma cell line 8701-BC. (PubMed id 8370623)9 Alessandro R....Woolley D.E. (1993)
    190. Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas. (PubMed id 7677979)9 Muller D....Methlin G. (1993)
    191. Isolation and characterization of a high molecular weight type IV collagenase isolated from human carcinoma tissue. (PubMed id 8384126)9 Tsuda T.T....Tsuda M. (1993)
    192. Overproduction of metalloproteinases by v-mos-transfo rmed rat kidney (6m2) cells. (PubMed id 1602817)9 Chan J.C. (1992)
    193. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. (PubMed id 1793490)9 McDonnell S....Matrisian L.M. (1991)
    194. TGF-beta1 + EGF-initiated invasive potential in transformed human keratinocytes is coupled to a plasmin/MMP-10/MMP-1-dependent collagen remodeling axis: role for PAI-1. (PubMed id 19383899)9 Wilkins-Port C.E....Higgins P.J. (2009)
    195. [Laminin-dependent inflammatory response in synovial fibroblasts of rheumatoid arthritis patients] (PubMed id 18214499)9 Aicher W.K....Gay S. (2008)
    196. Gene expression changes in SNAP-stimulated and iNOS-transfected tenocytes--expression of extracellular matrix genes and its implications for tendon-healing. (PubMed id 16865710)9 Molloy T.J....Murrell G.A. (2006)
    197. Prognostic significance of stromelysin-3 and tissue inhibitor of matrix metalloproteinase-2 in esophageal cancer. (PubMed id 15557792)9 Sharma R....Ralhan R. (2004)
    198. Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer. (PubMed id 14694517)9 Impola U....Saarialho-Kere U. (2004)

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    Entrez Gene: 4319 HGNC: 7156 AceView: MMP10 Ensembl:ENSG00000166670 euGenes: HUgn4319
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