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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MMD2 Gene

protein-coding   GIFtS: 47
GCID: GC07M004945

Monocyte To Macrophage Differentiation-Associated 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Monocyte To Macrophage Differentiation-Associated 21 2     Monocyte To Macrophage Differentiation Factor 22
Progestin And AdipoQ Receptor Family Member 102 3     Monocyte-To-Macrophage Differentiation Factor 22
Progestin And AdipoQ Receptor Family Member X2 3     Monocyte-To-Macrophage Differentiation-Associated Protein 22
PAQR102 3     

External Ids:    HGNC: 301331   Entrez Gene: 2219382   Ensembl: ENSG000001362977   OMIM: 6145815   UniProtKB: Q8IY493   

Export aliases for MMD2 gene to outside databases

Previous GC identifers: GC07M004691 GC07M004719 GC07M004912 GC07M004861


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MMD2 Gene:
This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are
evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined
by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to
modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms.
(provided by RefSeq, Jun 2012)

GeneCards Summary for MMD2 Gene: 
MMD2 (monocyte to macrophage differentiation-associated 2) is a protein-coding gene. Diseases associated with MMD2 include muscular dystrophy, and crohn's disease. An important paralog of this gene is MMD.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MMD2 gene promoter:
         MAZR   NRSF form 1   Nkx5-1   NRSF form 2   GATA-1   Egr-2   HSF2   FOXO1a   STAT3   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MMD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MMD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1   Ensembl cytogenetic band:  7p22.1   HGNC cytogenetic band: 7p22

MMD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MMD2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M004945:  view genomic region     (about GC identifiers)

Start:
4,945,620 bp from pter      End:
4,998,844 bp from pter
Size:
53,225 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 4,991,975-5,045,199     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PAQRA_HUMAN, Q8IY49 (See protein sequence)
Recommended Name: Monocyte to macrophage differentiation factor 2  
Size: 270 amino acids; 31264 Da
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein
Secondary accessions: B5MBW4 Q6NVU5 Q6TCH0
Alternative splicing: 3 isoforms:  Q8IY49-1   Q8IY49-2   Q8IY49-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MMD2: NX_Q8IY49

Explore proteomics data for MMD2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IY49

  • MMD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MMD2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001094070.1  NP_001257304.1  NP_940685.3  

    ENSEMBL proteins: 
     ENSP00000385963   ENSP00000384690   ENSP00000384141  

    Human Recombinant Protein Products for MMD2: 
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    Novus Biologicals MMD2 Protein
    Novus Biologicals MMD2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for MMD2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0048471perinuclear region of cytoplasm IDA--

    MMD2 for ontologies           About GeneDecksing



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    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MMD2 
    Cloud-Clone Corp. CLIAs for MMD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004254 HlyIII-related

    Graphical View of Domain Structure for InterPro Entry Q8IY49

    ProtoNet protein and cluster: Q8IY49

    1 Blocks protein domain: IPB004254 Hly-III related proteins

    UniProtKB/Swiss-Prot: PAQRA_HUMAN, Q8IY49
    Similarity: Belongs to the ADIPOR family


    MMD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MMD2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MMD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MMD2 
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    miRNA
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate MMD2 (see all 22):
    hsa-miR-3910 hsa-miR-193a-3p hsa-miR-892b hsa-miR-3673 hsa-miR-429 hsa-miR-4288 hsa-miR-632 hsa-miR-346
    SwitchGear 3'UTR luciferase reporter plasmidMMD2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for MMD2
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    GenScript: all cDNA clones in your preferred vector: MMD2 (NM_016094)
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMD2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MMD2

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019835cytolysis ----

    MMD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MMD2 (PAQRA)

    Search CenterWatch for drugs/clinical trials and news about MMD2 / PAQRA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MMD2 gene (3 alternative transcripts): 
    NM_001100600.1  NM_001270375.1  NM_198403.3  

    Unigene Cluster for MMD2:

    Monocyte to macrophage differentiation-associated 2
    Hs.558694  [show with all ESTs]
    Unigene Representative Sequence: NM_001100600
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000406755(uc010ksq.3) ENST00000404774(uc003snl.1 uc003snn.4 uc003sno.4)
    ENST00000401401
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MMD2
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate MMD2 (see all 22):
    hsa-miR-3910 hsa-miR-193a-3p hsa-miR-892b hsa-miR-3673 hsa-miR-429 hsa-miR-4288 hsa-miR-632 hsa-miR-346
    SwitchGear 3'UTR luciferase reporter plasmidMMD2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MMD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMD2
    Clone
    Products:
         
    OriGene clones in human, mouse for MMD2 (see all 13)
    OriGene ORF clones in mouse, rat for MMD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MMD2 (NM_016094)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MMD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMD2
    Sirion Biotech Customized lentivirus for stable overexpression of MMD2 
                         Customized lentivirus expression plasmids for stable overexpression of MMD2 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MMD2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MMD2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMD2

    Additional mRNA sequence: 

    AK094524.1 AY424288.1 BC037881.1 BC048346.1 BC067905.1 NR_072989.1 

    2 DOTS entries:

    DT.101979445  DT.206969 

    24/72 AceView cDNA sequences (see all 72):

    BM725350 AK000997 AI076876 BF114928 CR598494 AL044980 AB058752 BQ070639 
    AW296772 BM799509 AK001186 NM_018059 AK094524 BQ232134 AL535725 BQ422998 
    BE728860 BC048346 BX415125 BE276824 BE885462 BF448533 AU118216 AI041242 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MMD2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:                                -                           
    SP2:                                            -               
    SP3:                                -           -               


    ECgene alternative splicing isoforms for MMD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MMD2 expression in normal human tissues (normalized intensities)      MMD2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATCTGGGGC
    MMD2 Expression
    About this image


    MMD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 11 entries
             Thalamus
             ganglion/cranial/facial VII   
     
     Neural Tube (Nervous System)    fully expand to see all 8 entries
             Metencephalon
             brain/midbrain/lateral wall   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Periportal Hepatocytes Liver Lobule
             Liver Lobule
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See MMD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MMD2

    SOURCE GeneReport for Unigene cluster: Hs.558694

    UniProtKB/Swiss-Prot: PAQRA_HUMAN, Q8IY49
    Tissue specificity: Shows restricted expression with highest levels in brain and testis

        SABiosciences Custom PCR Arrays for MMD2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MMD2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mmd21 , 5 monocyte to macrophage differentiation-associated 21, 5 88.98(n)1
    96.69(a)1
      5 (81.53 cM)5
    751041  NM_175217.61  NP_780426.11 
     1425634805 
    chicken
    (Gallus gallus)
    Aves MMD21 monocyte to macrophage differentiation-associated 2 81.71(n)
    83.74(a)
      416480  XM_414787.2  XP_414787.2 
    lizard
    (Anolis carolinensis)
    Reptilia MMD26
    Uncharacterized protein
    76(a)
    1 ↔ 1
    GL343591.1(243043-256518)
    zebrafish
    (Danio rerio)
    Actinopterygii mmd21 progestin and adipoQ receptor 10 72.78(n)
    74.58(a)
      558749  NM_001174058.1  NP_001167529.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG46156
    --
    33(a)
    1 → many
    X(6992611-6996333)
    worm
    (Caenorhabditis elegans)
    Secernentea Y71G12B.236
    Protein Y71G12B.23, isoform b
    36(a)
    1 → many
    I(1670079-1672742)


    ENSEMBL Gene Tree for MMD2 (if available)
    TreeFam Gene Tree for MMD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MMD2 gene
    MMD2  
    1 SIMAP similar gene for MMD2 using alignment to 2 protein entries:     PAQRA_HUMAN (see all proteins):
    MMD

    MMD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1839 SNPs in MMD2 are shown (see all 1839)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1450153841,2
    --4915889(+) TCCTTC/GACCTC 4 -- us2k10--------
    rs1164097651,2
    F--4915967(+) ATTTCG/ACCACT 4 -- us2k11Minor allele frequency- A:0.06WA 118
    rs355812221,2
    C,F--4916003(+) TAAGTA/GGATGC 4 -- us2k18Minor allele frequency- G:0.28NA CSA WA EA 367
    rs1486864681,2
    --4916053(+) GTGGGA/GGATGG 4 -- us2k10--------
    rs2006078321,2
    C--4931383(+) CCTATC/GTATGT 1 -- ds50010--------
    rs1419076841,2
    C--4931387(+) CTATG-/TATC  
            
    TATCT
    1 -- ds50010--------
    rs2019644541,2
    C--4931442(+) ATCTAC/TCTACC 1 -- ds50010--------
    rs1998601591,2
    C--4931446(+) ACCTAC/TCTATC 1 -- ds50010--------
    rs2015965381,2
    C--4931455(+) TCTATC/GTATCT 1 -- ds50010--------
    rs3698230821,2
    C--4931455(+) CTATG-/TATC  
            
    TATCT
    1 -- ds50010--------

    HapMap Linkage Disequilibrium report for MMD2 (4945620 - 4998844 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MMD2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2659019CNV Deletion23128226
    nsv887389CNV Loss21882294
    nsv528748CNV Loss19592680
    nsv8033CNV Loss18304495

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for MMD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614581    OMIM disorders: --

    6 diseases for MMD2:    About MalaCards
    muscular dystrophy    crohn's disease    pneumonia    tuberculosis
    hepatitis b    hepatitis


    MMD2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MMD2
    Human Genome Epidemiology (HuGE) Navigator: MMD2 (5 documents)

    Export disorders for MMD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MMD2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with MMD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the topology and functional domains of PAQR10. (PubMed id 22339580)1, 2 Jin T.... Chen Y. (2012)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Fucosyltransferase 2 (FUT2) non-secretor status is as sociated with Crohn's disease. (PubMed id 20570966)1, 4 McGovern D.P....Rotter J.I. (2010)
    4. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
    5. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. (PubMed id 16044242)1, 2 Tang Y.T....Funk W.D. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    8. PAQR10 and PAQR11 mediate Ras signaling in the Golgi a pparatus. (PubMed id 21968647)1 Jin T....Chen Y. (2012)
    9. Mesenchymal stem cell derived hematopoietic cells are permissive to HIV-1 infection. (PubMed id 21226936)1 Nazari-Shafti T.Z....Izadpanah R. (2011)
    10. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221938 HGNC: 30133 AceView: FLJ10324 Ensembl:ENSG00000136297 euGenes: HUgn221938
    ECgene: MMD2 H-InvDB: MMD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MMD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MMD2 gene:
    Search GeneIP for patents involving MMD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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