Aliases for MMD Gene
External Ids for MMD Gene
Previous GeneCards Identifiers for MMD Gene
This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]
GeneCards Summary for MMD Gene
MMD (Monocyte To Macrophage Differentiation Associated) is a Protein Coding gene. Diseases associated with MMD include Muscular Dystrophy, Limb-Girdle, Type 2B and Myopathy, Distal, With Anterior Tibial Onset. GO annotations related to this gene include protein kinase activity and receptor activity. An important paralog of this gene is MMD2.
UniProtKB/Swiss-Prot for MMD Gene
Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion.