MMADHC Gene
protein-coding GIFtS: 50
GCID: GC02M150426
|
|
methylmalonic aciduria (cobalamin deficiency) cblD type,...(Previous name: chromosome 2 open reading frame 25 )
(Previous symbol: C2orf25)
| |
Aliases
for MMADHC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methylmalonic Aciduria (Cobalamin Deficiency) CblD Type, WithHomocystinuria1 2 | | Chromosome 2 Open Reading Frame 251 | | C2orf251 2 3 5 | | Methylmalonic Aciduria And Homocystinuria Type D Protein, Mitochondrial2 | | CL250221 2 3 | | Protein C2orf25, Mitochondrial2 | | CblD1 | | |
Export aliases for MMADHC gene to outside databasesPrevious GC identifers: GC02M150135 GC02M142325 |
Summaries
for MMADHC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MMADHC:
This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12(cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonicaciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreasedlevels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 andX.(provided by RefSeq, Nov 2008)
UniProtKB/Swiss-Prot: MMAD_HUMAN, Q9H3L0Function: Involved in cobalamin metabolism
Gene Wiki entry for MMADHC
|
Genomic Views
for MMADHC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MMADHC gene promoter:
IRF-2 AML1a Pax-2b MyoD Pax-2 STAT5A Pax-2a
Other transcription factors
Search SABiosciences Chromatin IP Primers for MMADHC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMADHC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q23.2 Ensembl cytogenetic band: 2q23.2 HGNC cytogenetic band: 2q23MMADHC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M150426: view genomic region
(about GC identifiers)
Start:
|
150,426,147 bp from pter |
End:
|
150,444,330 bp from pter |
Size:
|
18,184 bases |
Orientation:
|
minus strand |
|
Proteins
for MMADHC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MMAD_HUMAN, Q9H3L0 (See
protein sequence)Recommended Name: Methylmalonic aciduria and homocystinuria type D protein, mitochondrial precursor Size: 296 amino acids; 32940 Da
Subcellular location: Mitochondrion (Potential)
Sequence caution: Sequence=AAG43124.1; Type=Frameshift; Positions=171, 178, 185, 188, 200;
Secondary accessions: B2R895 D3DP91 O95891Explore the universe of human proteins at neXtProt for MMADHC: NX_Q9H3L0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H3L0
MMADHC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056517.1
ENSEMBL proteins: ENSP00000301920 ENSP00000389060 ENSP00000408331 ENSP00000388767
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IEA | -- |
MMADHC for ontologies About GeneDecksing
MMADHC Antibody Products:
Assay Products for MMADHC: |
Protein
Domains /
Families
for MMADHC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MMADHC for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H3L0ProtoNet protein and cluster: Q9H3L0 |
Function
for MMADHC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MMAD_HUMAN, Q9H3L0Function: Involved in cobalamin metabolism
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for MMADHC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMADHC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMADHC |
2 GenomeRNAi human phenotypes for MMADHC:
|
Pathways & Interactions
for MMADHC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MMADHC
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for MMADHC (Q9H3L03 ENSP000003019204) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0009235 | cobalamin metabolic process |
IEA | -- |
MMADHC for ontologies About GeneDecksing
|
Drugs & Compounds
for MMADHC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MMADHC
Search CenterWatch for drugs/clinical trials and news about MMADHC / MMAD
|
Transcripts
for MMADHC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MMADHC gene: NM_015702.2 Unigene Cluster for MMADHC: Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria Hs.5324 [show with all ESTs]Unigene Representative Sequence: BF5723375 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000303319(uc002txc.3) ENST00000428879 ENST00000422782 ENST00000436114
ENST00000460311
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MMADHC (NM_015702) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MMADHC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMADHC |
Additional cDNA sequence: AF060224.1 AF131802.1 AF161510.1 AK310001.1 AK313284.1 BC000932.2 BC010894.1 BC022859.1 BC023995.1 19 DOTS entries: DT.100859971 DT.87017011 DT.100038482 DT.100859978 DT.70103092 DT.100038483 DT.121014890 DT.100859980 DT.121014918 DT.100859967 DT.121014895 DT.91793536 DT.95375204 DT.100859968 DT.121014850 DT.121014901 DT.121014928 DT.95375194 DT.95375198 24/1041 AceView cDNA sequences (see all 1041): AA234377 BP353542 CB160879 BM761451 CB149624 CA406443 BP356089 BM788648 BM843509 AA877327 BI522529 AA626594 BI857492 CR596944 AW501996 CR626278 CR594994 BP336849 BE766222 BP352776 BQ227417 BP374595 BM806628 AA428971
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MMADHC (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b |
|---|
|
| SP1: | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MMADHC
|
Expression
for MMADHC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MMADHC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGTTGTAGG
About this image
See MMADHC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MMADHC
SOURCE GeneReport for Unigene cluster: Hs.5324
UniProtKB/Swiss-Prot: MMAD_HUMAN, Q9H3L0Tissue specificity: Widely expressed at high levels
SABiosciences Custom PCR Arrays for MMADHC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMADHC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MMADHC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMADHC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMADHC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMADHC |
Orthologs
for MMADHC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MMADHC gene from 7/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mmadhc1 , 5 |
methylmalonic aciduria (cobalamin deficiency) cblD more1, 5 |
89.08(n)1
93.58(a)1 |
|
2 (28.92 cM)5
1091291 NM_133839.21 NP_598600.11
502798815 |
chicken
(Gallus gallus) |
Aves |
MMADHC1 |
methylmalonic aciduria (cobalamin deficiency) cblD more |
78.27(n)
83.45(a) |
|
424311 NM_001008477.1 NP_001008477.1 |
lizard
(Anolis carolinensis) |
Reptilia |
MMADHC6 |
-- |
80(a) |
1 ↔ 1 |
GL343302.1(301234-310166) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.77312 |
Xenopus laevis transcribed sequence with moderate similarity more |
76.42(n) |
|
BX843016.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.291372 |
Danio rerio My011 protein (My011) mRNA, complete cds |
72.75(n) |
|
AY391443.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG121186 |
-- |
21(a) |
1 ↔ 1 |
X(9088783-9090447) |
worm
(Caenorhabditis elegans) |
Secernentea |
Y76A2B.51 |
Protein Y76A2B.5 |
53.68(n)
42.72(a) |
|
176786 NM_067400.7 NP_499801.1 |
ENSEMBL Gene Tree for MMADHC (if available)
TreeFam Gene Tree for MMADHC (if available) |
Paralogs
for MMADHC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MMADHC gene
18 SIMAP similar genes for MMADHC using alignment to 3 protein entries: MMAD_HUMAN (see all proteins):NLRC5 SEC14L3 SNRPF COQ5 NLN ACTR10
C12orf76 DYNC2LI1 EEF1E1 RRM2B DOCK8 MST132
TUBA1C ADCK1 PFKFB3 SEPSECS KIAA0101 RHBG
MMADHC for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for MMADHC
PGOHUM00000242207 PGOHUM00000241863
|
Genomic Variants
for MMADHC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MMADHC (150426147 - 150444330 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MMADHC: --
Human Gene Mutation Database (HGMD): MMADHC
Locus Specific Mutation Databases (LSDB): MMADHC
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for MMADHC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MMADHC for disorders About GeneDecksing
OMIM gene information: 611935
OMIM disorders: 277410
UniProtKB/Swiss-Prot: MMAD_HUMAN, Q9H3L0
Defects in MMADHC are the cause of methylmalonic aciduria and homocystinuria type cblD (MMAHCD) [MIM:277410].A disorder of cobalamin metabolism characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) andmethylcobalamin (MeCbl). Clinical features include developmental delay, hyotonia, mental retardation, seizures,megaloblastic anemia. Some patients manifest combined methylmalonic aciduria and homocystinuria (referred to as cblDoriginal), some have only isolated homocystinuria (cblD variant 1), and others have only methylmalonic aciduria (cblDvariant 2)
11  diseases for MMADHC: About MalaCardscbld methylmalonic aciduria and homocystinuria methylmalonic aciduria and homocystinuria type cbld homocystinuria
methylmalonic aciduria, cbld type, variant 2 disorders of intracellular cobalamin metabolism cbld (variant 2) cbld (variant 1)
methylmalonic acidemia megaloblastic anemia anemia
2 diseases from the University of Copenhagen DISEASES database for MMADHC:Methylmalonic acidemia Homocystinuria GeneTests: MMADHC
Methylmalonic AcidemiaDisorders of Intracellular Cobalamin Metabolism
Human Genome Epidemiology (HuGE) Navigator: MMADHC (4 documents)
Export disorders for MMADHC gene to outside databases
|
Publications
for MMADHC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MMADHC gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with MMADHC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Gene identification for the cblD defect of vitamin B12 metabolism. (PubMed id 18385497)1, 2, 3 Coelho D.... Fowler B. (2008)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Molecular mechanisms leading to three different phenot ypes in the cblD defect of intracellular cobalamin metabolism. (PubMed id 22156578)1 Stucki M....Baumgartner M.R. (2012)
- Interaction between MMACHC and MMADHC, two human prot eins participating in intracellular vitamin Ba88a88 metabolism. (PubMed id 21071249)1 Plesa M....Coulton J.W. (2011)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for MMADHC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MMADHC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MMADHC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MMADHC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MMADHC | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/MMADHC |
|
| | |
About This Section
| Patent Information for MMADHC gene:
Search GeneIP for patents involving MMADHC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MMADHC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MMADHC | | OriGene shRNA RFP for MMADHC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MMADHC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MMADHC | | | OriGene Protein Over-expression Lysate for MMADHC | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MMADHC | | OriGene 3'-UTR Clone for MMADHC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MMADHC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MMADHC | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MMADHC | | OriGene Custom Protein Services for MMADHC | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MMADHC | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MMADHC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MMADHC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MMADHC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MMADHC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MMADHC |
| |
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| | | | Search Tocris compounds for MMADHC |
| |  |  |  |  | | | | |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MMADHC |
|  |  |  | | | | Search ThermoFisher Antibodies for MMADHC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MMADHC |
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