MLX Gene
protein-coding GIFtS: 56
GCID: GC17P040719
|
|
MLX, MAX dimerization protein(Previous names: transcription factor-like 4, MAX-like protein X )
(Previous symbol: TCFL4)
| |
Aliases
for MLX gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MLX, MAX Dimerization Protein1 2 | | Max-Like BHLHZip Protein2 3 | | TCFL41 2 3 5 | | Transcription Factor-Like Protein 42 3 | | BHLHd131 | | Transcription Factor-Like 41 | | MAD71 2 | | BigMax Protein2 | | MXD71 2 | | BHLHD133 | | MAX-Like Protein X1 2 | | Protein BigMax3 | | Class D Basic Helix-Loop-Helix Protein 132 3 | | |
Export aliases for MLX gene to outside databasesPrevious GC identifers: GC17P037973 GC17P036483 |
Summaries
for MLX gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MLX:
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcriptionfactors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination anddifferentiation. This gene product may act to diversify Mad family function by its restricted association with asubset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcriptvariants encoding different isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MLX_HUMAN, Q9UH92Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes aretranscriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved inglucose-responsive gene regulation
Gene Wiki entry for MLX
|
Genomic Views
for MLX gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MLX gene promoter:
Egr-3 PPAR-gamma1 Pax-6 Pax-2a PPAR-gamma2 C/EBPalpha HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MLX
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLX |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.1 Ensembl cytogenetic band: 17q21.2 HGNC cytogenetic band: 17q21.1MLX Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P040719: view genomic region
(about GC identifiers)
Start:
|
40,719,078 bp from pter |
End:
|
40,725,257 bp from pter |
Size:
|
6,180 bases |
Orientation:
|
plus strand |
|
Proteins
for MLX gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MLX_HUMAN, Q9UH92 (See
protein sequence)Recommended Name: Max-like protein X Size: 298 amino acids; 33300 Da
Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAD1,MAD4, MNT, WBSCR14 and MLXIP. Can also bind DNA as a homodimer
Subcellular location: Isoform Alpha: Cytoplasm. Note=Found predominantly in the cytoplasm
Subcellular location: Isoform Beta: Cytoplasm. Note=Found predominantly in the cytoplasm
Subcellular location: Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus
Secondary accessions: A8K2J3 B2RAV8 B2RD73 Q53XM6 Q96FL2 Q9H2V0 Q9H2V1 Q9H2V2 Q9NXN3Alternative splicing: 3 isoforms: Q9UH92-1 Q9UH92-2 Q9UH92-3 Explore the universe of human proteins at neXtProt for MLX: NX_Q9UH92
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UH92
MLX Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_733752.1 NP_937847.1 NP_937848.1
ENSEMBL proteins: ENSP00000416627 ENSP00000246912 ENSP00000320913 ENSP00000464697 Reactome Protein details: Q9UH92
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MLX for ontologies About GeneDecksing
MLX Antibody Products:
Assay Products for MLX: |
Protein
Domains /
Families
for MLX gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MLX for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9UH92ProtoNet protein and cluster: Q9UH92 1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH
UniProtKB/Swiss-Prot: MLX_HUMAN, Q9UH92Similarity: Contains 1 bHLH (basic helix-loop-helix) domain |
Function
for MLX gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MLX_HUMAN, Q9UH92Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes aretranscriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved inglucose-responsive gene regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLX (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLX (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MLX (NM_198204) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLX | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLX |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLX |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
MLX for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MLX:
|
Pathways & Interactions
for MLX gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Regulation of Insulin Secretion | | | 3 | Saturated fatty acid biosynthesis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for MLX
MLX for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MLX
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/15 Interacting proteins for MLX (Q9UH922, 3 ENSP000002469124) via UniProtKB, MINT, STRING, and/or I2D (see all 15)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006112 | energy reserve metabolic process |
TAS | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | 10918583 | | GO:0006913 | nucleocytoplasmic transport |
IEA | -- | | GO:0031325 | positive regulation of cellular metabolic process |
TAS | -- |
MLX for ontologies About GeneDecksing
|
Drugs & Compounds
for MLX gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MLX for compounds About GeneDecksing
 Browse Tocris compounds for MLX
2 Novoseek chemical compound relationships for MLX gene About this table
Search CenterWatch for drugs/clinical trials and news about MLX
|
Transcripts
for MLX gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MLX gene (3 alternative transcripts): NM_170607.2 NM_198204.1 NM_198205.1 Unigene Cluster for MLX: MLX, MAX dimerization protein Hs.714749 [show with all ESTs]Unigene Representative Sequence: AB20923511 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000435881(uc002iaf.3) ENST00000246912(uc002iag.3) ENST00000346833(uc002iah.3)
ENST00000590050 ENST00000591024 ENST00000590084 ENST00000592717 ENST00000585403
ENST00000586393 ENST00000591195 ENST00000588320
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLX (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLX (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): MLX (NM_198204) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLX | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLX |
Additional cDNA sequence: AB209235.1 AF203978.1 AF213666.1 AF213667.1 AF213668.1 AK000150.1 AK290258.1 AK296114.1 AK303221.1 AK309628.1 AK314378.1 AK315432.1 BC010689.2 BT009812.1 24 DOTS entries: DT.92408048 DT.100828409 DT.218914 DT.100828407 DT.40228569 DT.100029552 DT.100029556 DT.436496 DT.100828411 DT.100828413 DT.95144397 DT.102828323 DT.92458983 DT.92458956 DT.100828408 DT.120921202 DT.120921218 DT.91856392 DT.91975284 DT.95200371 DT.120921227 DT.91883573 DT.92416326 DT.95167154 24/808 AceView cDNA sequences (see all 808): CA443298 BU193826 BM480288 AL134943 BE676231 AA836879 BU676002 BM560518 BM835182 BM755564 BG697372 BQ013840 BM666748 BM825430 AX747572 AL583142 BM781531 BM694192 NM_198205 BM789014 BM722801 CB112870 BQ718106 BU737373
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for MLX (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | - | | | | - | | | | | | - | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | - | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP5: | | | | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MLX
|
Expression
for MLX gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MLX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTCAGTGTT
About this image
See MLX Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MLX
SOURCE GeneReport for Unigene cluster: Hs.714749
UniProtKB/Swiss-Prot: MLX_HUMAN, Q9UH92Tissue specificity: Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon,peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain,placenta and lung
SABiosciences Expression via Pathway-Focused PCR Array including MLX:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MLX
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MLX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MLX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MLX | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLX |
Orthologs
for MLX gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MLX gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MLX1 |
MAX-like protein X |
79.69(n)
84.87(a) |
|
420026 NM_001030930.1 NP_001026101.1 |
lizard
(Anolis carolinensis) |
Reptilia |
MLX6 |
-- |
84(a) |
1 ↔ 1 |
6(61752727-61760359) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.150072 |
Xenopus laevis transcribed sequence with moderate similarity more |
76.21(n) |
|
CA789463.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
CD052797.12 |
-- |
78.1(n) |
|
322434 CD052797.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
bigmax1 |
CG3350-PA |
60(n)
51(a) |
|
43293 NM_143299.2 NP_651556.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
mxl-26 |
MaX-Like family member (mxl-2) |
17(a) |
1 ↔ 1 |
III(186944-188130) |
ENSEMBL Gene Tree for MLX (if available)
TreeFam Gene Tree for MLX (if available) |
Paralogs
for MLX gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MLX gene
- MLXIP2 MLXIPL2
2 SIMAP similar genes for MLX using alignment to 2 protein entries: MLX_HUMAN (see all proteins):MAX ARNTL
MLX for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MLX
PGOHUM00000241121
|
Genomic Variants
for MLX gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MLX (40719078 - 40725257 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MLX: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MLX |
|
Disorders
/ Diseases
for MLX gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MLX for disorders About GeneDecksing
OMIM gene information: 602976
OMIM disorders: --
4  diseases for MLX: About MalaCardswilliams-beuren syndrome cerebrovascular accident hepatitis prostatitis
3 diseases from the University of Copenhagen DISEASES database for MLX:Cerebrovascular accident Heart disease Hypertension Human Genome Epidemiology (HuGE) Navigator: MLX (2 documents)
Export disorders for MLX gene to outside databases
|
Publications
for MLX gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MLX gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with MLX) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mlx, a novel Max-like bHLHZip protein that interacts with the Max network of transcription factors. (PubMed id 10593926)1, 2, 9 Billin A.N.... Ayer D.E. (1999)
- Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? (PubMed id 10918583)1, 2, 9 Meroni G....Reymond A. (2000)
- TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor. (PubMed id 8973301)1, 3, 9 Bjerknes M. and Cheng H. (1996)
- MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. (PubMed id 16782875)1, 2 Sans C.L.... Ayer D.E. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex. (PubMed id 12446771)1, 2 Eilers A.L.... Ayer D.E. (2002)
- Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. (PubMed id 18458340)1, 9 Stoltzman C.A....Ayer D.E. (2008)
- Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes. (PubMed id 15664996)1, 9 Ma L....Towle H.C. (2005)
- MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network. (PubMed id 11073985)1, 9 Billin A.N.... Ayer D.E. (2000)
|
External Searches for MLX gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MLX gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MLX gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MLX gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MLX | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MLX gene:
Search GeneIP for patents involving MLX
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MLX gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MLX | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MLX | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MLX | | | OriGene Protein Over-expression Lysate for MLX | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MLX | | OriGene 3'-UTR Clone for MLX | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLX | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLX | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MLX | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MLX | | OriGene Custom Protein Services for MLX | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MLX | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MLX | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLX | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MLX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MLX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MLX |
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| | | | Search Tocris compounds for MLX |
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 | | | MLX Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLX |
|  |  |  | | | | Search ThermoFisher Antibodies for MLX |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLX |
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