MLLT10 Gene
protein-coding GIFtS: 54
GCID: GC10P021825
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|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog,...(Previous names: myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila)...)
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Aliases
for MLLT10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila);Translocated To, 101 2 | | Protein AF-102 | | AF101 2 3 5 | | Type I AF10 Protein2 | | ALL1-Fused Gene From Chromosome 10 Protein2 3 | | Type III AF10 Protein2 | | Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog);Translocated To, 101 | | Type IV AF10 Protein2 |
Export aliases for MLLT10 gene to outside databasesPrevious GC identifers: GC10P021558 GC10P021973 GC10P021827 GC10P021863 GC10P021469 |
Summaries
for MLLT10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MLLT10:
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomalrearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have beenfound for this gene. (provided by RefSeq, Sep 2010)
UniProtKB/Swiss-Prot: AF10_HUMAN, P55197Function: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivationactivity. Binds to cruciform DNA
Gene Wiki entry for MLLT10
|
Genomic Views
for MLLT10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MLLT10 gene promoter:
POU3F1 HFH-1 Ik-3 Arnt c-Ets-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MLLT10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLLT10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p12 Ensembl cytogenetic band: 10p12.31 HGNC cytogenetic band: 10p12MLLT10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P021825: view genomic region
(about GC identifiers)
Start:
|
21,823,094 bp from pter |
End:
|
22,032,559 bp from pter |
Size:
|
209,466 bases |
Orientation:
|
plus strand |
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Proteins
for MLLT10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AF10_HUMAN, P55197 (See
protein sequence)Recommended Name: Protein AF-10 Size: 1027 amino acids; 109026 Da
Subunit: Self-associates. Interacts with FSTL3 isoform 2; the interaction enhances MLLT10 in vitro transcriptionalactivity and self-association. Interacts with YEATS4. Interacts with SS18. Interacts with DOT1L
Subcellular location: Nucleus
Secondary accessions: B1ANA8 Q5JT37 Q66K63Alternative splicing: 3 isoforms: P55197-1 P55197-2 P55197-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MLLT10: NX_P55197
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P55197
MLLT10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001182555.1 NP_001182556.1 NP_001182557.1 NP_001182559.1 NP_004632.1
ENSEMBL proteins: ENSP00000366304 ENSP00000366272 ENSP00000307411 ENSP00000366295 ENSP00000397800 ENSP00000408281 ENSP00000399883 ENSP00000401406 ENSP00000366258
Human Recombinant Protein Products for MLLT10:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MLLT10 for ontologies About GeneDecksing
MLLT10 Antibody Products:
Assay Products for MLLT10: |
Protein
Domains /
Families
for MLLT10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MLLT10 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P55197ProtoNet protein and cluster: P55197 1 Blocks protein family: IPB001965 Zn-finger-like
UniProtKB/Swiss-Prot: AF10_HUMAN, P55197Similarity: Contains 2 PHD-type zinc fingers |
Function
for MLLT10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: AF10_HUMAN, P55197Function: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivationactivity. Binds to cruciform DNA Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
MLLT10 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for MLLT10:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): MLLT10 (NM_001195627) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLLT10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLLT10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLLT10 |
|
Pathways & Interactions
for MLLT10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MLLT10
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/23 Interacting proteins for MLLT10 (P551973 ENSP000003662724) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
-- | -- | | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter |
IDA | 17868029 |
MLLT10 for ontologies About GeneDecksing
|
Drugs & Compounds
for MLLT10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MLLT10 for compounds About GeneDecksing
 Browse Tocris compounds for MLLT10
3 Novoseek chemical compound relationships for MLLT10 gene About this table
Search CenterWatch for drugs/clinical trials and news about MLLT10 / AF10
|
Transcripts
for MLLT10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MLLT10 gene (6 alternative transcripts): NM_001195626.1 NM_001195627.1 NM_001195628.1 NM_001195630.1 NM_004641.3 NM_001009569.1 Unigene Cluster for MLLT10: Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 Hs.30385 [show with all ESTs]Unigene Representative Sequence: AB20975516 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377100(uc001iqr.2 uc001iqu.2 uc001iqq.2) ENST00000377072(uc001iqs.3 uc001iqv.3 uc001iqt.3)
ENST00000307729(uc021pny.1 uc001ira.3 uc001irb.3) ENST00000377091
ENST00000471315 ENST00000495130(uc001iqx.1 uc009xkf.1 uc009xke.1 uc001iqw.1)
ENST00000476557 ENST00000430455 ENST00000462999 ENST00000480415 ENST00000479634
ENST00000438473 ENST00000468309 ENST00000420525 ENST00000446906 ENST00000377059
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): MLLT10 (NM_001195627) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLLT10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLLT10 |
Additional cDNA sequence: AB209755.1 AF060927.1 AF060929.1 AF060932.1 AF060934.1 AF060935.1 AF060936.1 AF060937.1 AF060938.1 AF272385.1 AK126642.1 AK301213.1 AK310803.1 AL137295.1 AY598745.1 BC032532.1 BC052798.1 BC065376.1 BC080577.1 BC094844.1 BC129946.1 BX640774.1 BX648210.1 U13948.1 19 DOTS entries: DT.416343 DT.101980714 DT.95172977 DT.95172979 DT.101977940 DT.91741124 DT.121300683 DT.92471719 DT.40118519 DT.100764476 DT.107987 DT.121300612 DT.121300661 DT.75135685 DT.101968555 DT.121300666 DT.100823172 DT.309851 DT.87017228 24/220 AceView cDNA sequences (see all 220): BE551854 AL704352 NM_004641 BQ012851 BQ056555 AL046668 BM670709 AI630181 AI147420 AI537971 AF060937 AK128264 AA431263 BX109927 BX385970 AW129353 AI656923 BC052798 AF060935 BU617758 BU849048 BX648210 D62802 BE466876
GeneLoc Exon Structure
|
Expression
for MLLT10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MLLT10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTAAAATG
About this image
See MLLT10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MLLT10
SOURCE GeneReport for Unigene cluster: Hs.30385
UniProtKB/Swiss-Prot: AF10_HUMAN, P55197Tissue specificity: Expressed abundantly in testis
SABiosciences Custom PCR Arrays for MLLT10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MLLT10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MLLT10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MLLT10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MLLT10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLLT10 |
Orthologs
for MLLT10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MLLT10 gene from 8/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MLLT101 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax more |
84.76(n)
87.17(a) |
|
420509 XM_418610.3 XP_418610.3 |
lizard
(Anolis carolinensis) |
Reptilia |
MLLT106 |
-- |
78(a) |
1 ↔ 1 |
6(16565221-16690150) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.162972 |
Transcribed sequence with moderate similarity to protein more |
79.48(n) |
|
BX701108.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
mllt101 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax more |
71.01(n)
77.64(a) |
|
492342 XM_003201290.1 XP_003201338.1 |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
22(a) |
1 → many |
Group8.21(17358-22482) |
worm
(Caenorhabditis elegans) |
Secernentea |
zfp-13 |
Expression: intestine, pharynx, phasmid
sensilla, more |
59(a) |
|
III(8864569-8866029) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G778006 |
PHD finger-containing protein |
6(a) |
1 → many |
1(29253396-29260617) |
rice
(Oryza sativa) |
Liliopsida |
---- |
PHD-finger domain containing protein, putative, ex...PHD-finger domain containing protein, putative, ex... |
8(a)6(a) |
many ↔ manymany ↔ many |
6(5574868-5583374) 2(32378762-32390225) |
ENSEMBL Gene Tree for MLLT10 (if available)
TreeFam Gene Tree for MLLT10 (if available) |
Paralogs
for MLLT10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MLLT10 gene
- PHF152 PHF142 PHF172 PHF162 BRPF12 BRD12 MLLT62 BRPF32
7 SIMAP similar genes for MLLT10 using alignment to 6 protein entries: AF10_HUMAN (see all proteins):MLL/AF10 fusion AF10 DKFZp686E10210 DKFZp779J0967 PHF15 MLLT6
BRPF3
MLLT10 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for MLLT10
PGOHUM00000259181 PGOHUM00000262355 PGOHUM00000247503 PGOHUM00000245795
|
Genomic Variants
for MLLT10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MLLT10 (21823094 - 22032559 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MLLT10
2 CNVs: 70934 100889 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MLLT10 |
|
Disorders
/ Diseases
for MLLT10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MLLT10 for disorders About GeneDecksing
OMIM gene information: 602409
OMIM disorders: 601626
UniProtKB/Swiss-Prot: AF10_HUMAN, P55197
Note=A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocationt(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein Note=A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocationt(10;11)(p13;q14) with PICALM
16  diseases for MLLT10: About MalaCardsleukemia acute monocytic leukemia acute biphenotypic leukemia monocytic leukemia
lymphoblastic leukemia myeloid leukemia synovial sarcoma mediastinitis
acute lymphoblastic leukemia acute myeloid leukemia acute leukemia emphysema
sarcoma retinoblastoma myeloma schizophrenia
1 disease from the University of Copenhagen DISEASES database for MLLT10:Leukemia 10/11 Novoseek disease relationships for MLLT10 gene (see all 11) About this table
Human Genome Epidemiology (HuGE) Navigator: MLLT10 (3 documents)
Export disorders for MLLT10 gene to outside databases
|
Publications
for MLLT10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MLLT10 gene, integrated from 9 sources (see all 72):
(articles sorted by number of sources associating them with MLLT10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia. (PubMed id 7888665)1, 2, 3 Chaplin T.... Young B.D. (1995)
- AF10-dependent transcription is enhanced by its interaction with FLRG. (PubMed id 17868029)1, 2, 9 Forissier S....Rimokh R. (2007)
- The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex. (PubMed id 11756182)1, 2, 9 Debernardi S.... Young B.D. (2002)
- The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10. (PubMed id 11423977)1, 2, 9 de Bruijn D.R....Geurts van Kessel A. (2001)
- Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation. (PubMed id 10860745)1, 2, 9 Linder B.... Saha V. (2000)
- hDOT1L links histone methylation to leukemogenesis. (PubMed id 15851025)1, 2, 9 Okada Y.... Zhang Y. (2005)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10- CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14- q21) suggests a potential role for truncated AF10 polypeptides. (PubMed id 9737689)1, 9 Silliman C.C.... Hunger S.P. (1998)
- The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10. (PubMed id 11986236)2, 9 DiMartino J.F....Cleary M.L. (2002)
- The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions. (PubMed id 12482966)1, 9 Perrin L....Dura J.M. (2003)
|
External Searches for MLLT10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MLLT10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MLLT10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MLLT10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MLLT10 gene:
Search GeneIP for patents involving MLLT10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MLLT10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for MLLT10 | | OriGene shRNA RFP for MLLT10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MLLT10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MLLT10 | | | OriGene Protein Over-expression Lysate for MLLT10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MLLT10 | | OriGene 3'-UTR Clone for MLLT10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MLLT10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MLLT10 | | OriGene Custom Protein Services for MLLT10 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MLLT10 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MLLT10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLLT10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MLLT10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MLLT10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MLLT10 |
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| | | | Search Tocris compounds for MLLT10 |
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 | | | MLLT10 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLLT10 |
|  |  |  |  | | | | ThermoFisher Antibodies for MLLT10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLLT10 |
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