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MLF2 Gene

protein-coding   GIFtS: 55
GCID: GC12M006857

Myeloid Leukemia Factor 2

  See MLF2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Myeloid Leukemia Factor 21 2
Myelodysplasia-Myeloid Leukemia Factor 22 3
NTN42

External Ids:    HGNC: 71261   Entrez Gene: 80792   Ensembl: ENSG000000896937   OMIM: 6014015   UniProtKB: Q157733   

Export aliases for MLF2 gene to outside databases

Previous GC identifers: GC12P006734 GC12P006859 GC12M006553 GC12M006727


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MLF2 Gene:
MLF2 (myeloid leukemia factor 2) is a protein-coding gene. Diseases associated with MLF2 include myeloid leukemia, and leukemia. An important paralog of this gene is MLF1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_009759.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the MLF2 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 4   AP-2alpha isoform 2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMLF2 promoter sequence
   Search Chromatin IP Primers for MLF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MLF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13

MLF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MLF2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M006857:  view genomic region     (about GC identifiers)

Start:
6,857,158 bp from pter      End:
6,876,641 bp from pter
Size:
19,484 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MLF2_HUMAN, Q15773 (See protein sequence)
Recommended Name: Myeloid leukemia factor 2  
Size: 248 amino acids; 28147 Da

Explore the universe of human proteins at neXtProt for MLF2: NX_Q15773

Explore proteomics data for MLF2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MLF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005430.1  
    ENSEMBL proteins: 
     ENSP00000203630   ENSP00000438671   ENSP00000446317   ENSP00000439789   ENSP00000443829  
     ENSP00000442444   ENSP00000403941  

    MLF2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MLF2

     
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    antibodies-online proteins for MLF2 (2 products) 

     
    antibodies-online peptides for MLF2

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    antibodies-online antibodies for MLF2 (25 products) 

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    Cloud-Clone Corp. CLIAs for MLF2
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    antibodies-online kits for MLF2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019376 Myeloid_leukemia_factor

    Graphical View of Domain Structure for InterPro Entry Q15773

    ProtoNet protein and cluster: Q15773

    UniProtKB/Swiss-Prot: MLF2_HUMAN, Q15773
    Similarity: Belongs to the MLF family


    Find genes that share domains with MLF2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for MLF2:
    myelodysplasia/myeloid leukemia factor 2,cytoplasmic,ubiquitously expressed currently no evidence for the
    involvement of MLF2 in hematologic malignancies

    Phenotypes:
         1 GenomeRNAi human phenotype for MLF2:
     Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MLF2

    miRNA
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    miRTarBase miRNAs that target MLF2:
    hsa-mir-296-3p (MIRT038370), hsa-mir-92a-3p (MIRT049518), hsa-mir-744-5p (MIRT037535), hsa-mir-16-5p (MIRT051088)

    Block miRNA regulation of human, mouse, rat MLF2 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate MLF2:
    hsa-miR-587 hsa-miR-125a-5p hsa-miR-125b hsa-miR-3613-3p hsa-miR-889 hsa-miR-551b* hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidMLF2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MLF2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLF2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MLF2_HUMAN, Q15773: Cytoplasm (By similarity). Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with MLF2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MLF2
    Interactions:

        Search GeneGlobe Interaction Network for MLF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for MLF2 (Q157732, 3 ENSP000002036304) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABCD3P282883, ENSP000003592334I2D: score=2 STRING: ENSP00000359233
    AIFM1O958313, ENSP000002872954I2D: score=2 STRING: ENSP00000287295
    BAG2O958163, ENSP000003597274I2D: score=2 STRING: ENSP00000359727
    CIAO1O760713, ENSP000004182874I2D: score=2 STRING: ENSP00000418287
    MMS19Q96T763, ENSP000003598184I2D: score=2 STRING: ENSP00000359818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006952defense response IMP8661158

    Find genes that share ontologies with MLF2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MLF2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MLF2 gene: 
    NM_005439.2  

    Unigene Cluster for MLF2:

    Myeloid leukemia factor 2
    Hs.524214  [show with all ESTs]
    Unigene Representative Sequence: BM919311
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000203630(uc001qqp.3) ENST00000541305 ENST00000542154 ENST00000539187(uc009zey.1)
    ENST00000537126 ENST00000541346 ENST00000540710 ENST00000564181 ENST00000536207
    ENST00000536249 ENST00000435120(uc010sfi.2)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MLF2 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate MLF2:
    hsa-miR-587 hsa-miR-125a-5p hsa-miR-125b hsa-miR-3613-3p hsa-miR-889 hsa-miR-551b* hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidMLF2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MLF2
    Predesigned siRNA for gene silencing in human, mouse, rat MLF2
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    GenScript: all cDNA clones in your preferred vector: MLF2 (NM_005439)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLF2
    Primer
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    OriGene qPCR primer pairs and template standards for MLF2
    OriGene qSTAR qPCR primer pairs in human, mouse for MLF2
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MLF2
      QuantiTect SYBR Green Assays in human, mouse, rat MLF2
      QuantiFast Probe-based Assays in human, mouse, rat MLF2

    Additional mRNA sequence: 

    AF070539.1 AK289869.1 AK313998.1 BC000898.2 BC002340.2 BT019393.1 BT019432.1 CR541700.1 
    NR_026581.1 U57342.1 

    Selected DOTS entries (see all 28):

    DT.446208  DT.97764865  DT.100808935  DT.100885810  DT.100885826  DT.92470076  DT.40106225  DT.100758921 
    DT.121122958  DT.100765729  DT.100804081  DT.100885813  DT.121122841  DT.40132214  DT.92470108  DT.95187711 
    DT.100804491  DT.100885812  DT.100885815  DT.100885819  DT.121122840  DT.86835785  DT.86838340  DT.92470075 

    Selected AceView cDNA sequences (see all 725):

    BQ676790 CR594751 BM922110 BM845663 BQ949338 CB112654 BC000898 BE890938 
    CR612884 BI914764 BQ771948 AI148736 CD172295 AJ710334 AA316108 AI357711 
    BF594202 CR597712 BP339203 BF771912 AL555971 BM849168 CR590498 BM693920 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MLF2 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b
    SP1:                          -                                         -                       -               
    SP2:                          -                                                                                 
    SP3:                          -                             -     -     -     -     -           -               
    SP4:                          -                 -     -     -     -     -     -                                 
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for MLF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MLF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTGAAGGG
    MLF2 Expression
    About this image


    MLF2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 21) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
     
     Ovary (Reproductive System)
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    MLF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MLF2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.524214

    UniProtKB/Swiss-Prot: MLF2_HUMAN, Q15773
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLF2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MLF2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mlf21 , 5 myeloid leukemia factor 21, 5 89.47(n)1
    97.17(a)1
      6 (59.17 cM)5
    308531  NM_145385.21  NP_663360.11 
     1249313885 
    chicken
    (Gallus gallus)
    Aves MLF21 myeloid leukemia factor 2 77.82(n)
    86.36(a)
      418284  NM_001030776.2  NP_001025947.1 
    lizard
    (Anolis carolinensis)
    Reptilia MLF26
    myeloid leukemia factor 2
    85(a)
    1 ↔ 1
    GL343453.1(109015-120074)
    African clawed frog
    (Xenopus laevis)
    Amphibia CD303631.12   -- 71.95(n)    CD303631.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj39f092 Transcribed sequence with weak similarity to protein more 78.91(n)    CK138593.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mlf6
    Myelodysplasia/myeloid leukemia factor
    19(a)
    1 → many
    2R(11823398-11827578)


    ENSEMBL Gene Tree for MLF2 (if available)
    TreeFam Gene Tree for MLF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MLF2 gene
    MLF12  
    2 SIMAP similar genes for MLF2 using alignment to 5 protein entries:     MLF2_HUMAN (see all proteins):
    MLF1    DKFZp313B1621

    Find genes that share paralogs with MLF2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for MLF2
    PGOHUM00000260417


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MLF2 (see all 228)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0364294
    A colorectal cancer sample4--see VAR_0364292 F C mis40--------
    rs110643621,2
    C,F,H--6856696(+) TCTAGG/TCTCCT 2 -- ds50018Minor allele frequency- T:0.07NS NA WA 914
    rs778991801,2
    F--6856795(+) GGTTAT/CCTGAA 2 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1917287281,2
    --6856887(+) CCCAAC/TACATC 2 -- ds50010--------
    rs1415845751,2
    --6856960(+) TCACGA/CCCCAG 2 -- ds50010--------
    rs21786951,2
    C,F,A--6857000(+) ACCTGG/CCAGTG 2 -- ds50017Minor allele frequency- C:0.22NA WA CSA EA 366
    rs1846915351,2
    --6857074(+) GAGACA/GAGGAA 2 -- ds50010--------
    rs1899870311,2
    --6857141(+) AAAAGG/TACAGC 2 -- ds50010--------
    rs1930232101,2
    --6857195(+) AACACC/GTAGTT 2 -- ut31 nc-transcript-variant0--------
    rs10506291,2
    C,F,H--6857289(-) GGTTCC/TTAACT 2 -- ut31 nc-transcript-variantese315Minor allele frequency- T:0.05MN NS EA CSA WA NA 2256

    HapMap Linkage Disequilibrium report for MLF2 (6857158 - 6876641 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MLF2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv898635CNV Loss21882294
    nsv832323CNV Loss17160897
    nsv832322CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MLF2
    DNA2.0 Custom Variant and Variant Library Synthesis for MLF2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601401    OMIM disorders: --

    2 diseases for MLF2:    
    About MalaCards
    myeloid leukemia    leukemia


    Find genes that share disorders with MLF2           About GenesLikeMe

    Genetic Association Database (GAD): MLF2
    Human Genome Epidemiology (HuGE) Navigator: MLF2 (2 documents)

    Export disorders for MLF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MLF2 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with MLF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning, tissue distribution, and chromosomal localization of myelodysplasia/myeloid leukemia factor 2 (MLF2). (PubMed id 8661158)1, 2, 3 Kuefer M.U.... Morris S.W. (Genomics 1996)
    2. Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers. (PubMed id 18095154)1, 4 Walker L.C....Spurdle A.B. (Breast Cancer Res. Treat. 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    6. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    7. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PubMed id 22678362)1 Stehling O.... Lill R. (Science 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8079 HGNC: 7126 AceView: MLF2 Ensembl:ENSG00000089693 euGenes: HUgn8079
    ECgene: MLF2 H-InvDB: MLF2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MLF2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MLF2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MLF2 gene:
    Search GeneIP for patents involving MLF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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