MLF1 Gene
protein-coding GIFtS : 59 GCID: GC03 P158288
myeloid leukemia factor 1
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Aliasesfor MLF1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Myeloid Leukemia Factor 1 1 2 Myelodysplasia-Myeloid Leukemia Factor 12 3
Export aliases for MLF1 gene to outside databases Previous GC identifers: GC03P155550 GC03P159236 GC03P159570 GC03P159609 GC03P159771 GC03P155686
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Summariesfor MLF1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for MLF1 : This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Sep 2010) UniProtKB/Swiss-Prot: MLF1_HUMAN, P58340 Function : Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation andenhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus Gene Wiki entry for MLF1
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Genomic Viewsfor MLF1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NC_018914.1 NT_005612.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MLF1 gene promoter:Pax-6 NCX/Ncx POU6F1 (c2) FOXL1 POU2F1 POU2F1b POU2F1a FOXJ2 (long isoform) FOXJ2 POU2F1c Other transcription factors Search SABiosciences Chromatin IP Primers for MLF1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLF1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3q25.1 Ensembl cytogenetic band: 3q25.32 HGNC cytogenetic band: 3q25 MLF1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03P158288: view genomic region
(about GC identifiers )
Start: 158,288,952 bp from pter End:
158,325,041 bp from pter
Size: 36,090 bases Orientation:
plus strand
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Proteinsfor MLF1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MLF1_HUMAN, P58340 See
protein sequence )Recommended Name: Size : 268 amino acids; 30627 DaSubunit : Interacts with MLF1IP. Also interacts with NRBP1/MADM, YWHAZ/14-3-3-zeta and HNRPUL2/MANP. NRBP1 recruits aserine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 then binds to YWHAZ and is retained in the cytoplasm. Retained in the nucleus by binding to HNRPUL2. Binds to COPS3/CSN3 which is required for suppression of RFWD2 and activation of p53
Subcellular location : Cytoplasm. Nucleus. Note=In non-hematopoietic cells, resides primarily in the cytoplasm with somepunctate nuclear localization. Shuttles between the cytoplasm and nucleus. In hematopoietic cells, located preferentially in the nucleus. Found in the nucleolus when fused to NPM
2 PDB 3D structures from :3UAL (3D) 3UBW (3D) Secondary accessions : E9PEU9 Q2TLE3 Q2TLE5 Q8N8F8 Q96MH1Alternative splicing : 5 isoforms : P58340-1 P58340-2 P58340-3 P58340-5 P58340-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MLF1: NX_P58340 Post-translational modifications:
Phosphorylation is required for binding to YWHAZ (By similarity)1 View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_P58340 MLF1 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (6 alternative transcripts): NP_001123628.1 NP_001123629.1 NP_001182361.1 NP_001182362.1 NP_001182363.1 NP_071888.1 ENSEMBL proteins: ENSP00000420410 ENSP00000348157 ENSP00000417835 ENSP00000352025 ENSP00000419636 ENSP00000419637 ENSP00000419775 ENSP00000420134 ENSP00000418595 ENSP00000417141 ENSP00000417777 ENSP00000419241 ENSP00000417278 ENSP00000376568 Human Recombinant Protein Products for MLF1: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing MLF1 Antibody Products: Assay Products for MLF1:
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Protein
Domains /for MLF1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry P58340 ProtoNet protein and cluster: P58340
UniProtKB/Swiss-Prot: MLF1_HUMAN, P58340 Similarity : Belongs to the MLF family
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Functionfor MLF1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: MLF1_HUMAN, P58340 Function : Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation andenhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus
Genatlas biochemistry entry for MLF1 myelodysplasia/myeloid leukemia factor 1.31kDa,fused with NPM1 in myelodysplastic syndrome with translocation t(3;5)(q25.1;q34),cytoplasmic protein expressed in a variety of tissues,homolog to murine hemopoietic lineage switch HLS7 Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for MLF1 :Animal Models: Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 9 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 6 ): MLF1 (NM_001130156 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MLF1
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLF1
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Pathways & Interactionsfor MLF1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MLF1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)5/16 Interacting proteins for MLF1 (P58340 2 , 3 ENSP00000348157 4 via UniProtKB, MINT, STRING , and/or I2D (see all 16 )About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
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Drugs & Compoundsfor MLF1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for MLF1 1 Novoseek chemical compound relationship for MLF1 gene About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
glutamine
22.3
1
12354791 (1)
MLF1
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Transcriptsfor MLF1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MLF1 gene (6 alternative transcripts): NM_001130156.2 NM_001130157.2 NM_001195432.1 NM_001195433.1 NM_001195434.1 NM_022443.4 Unigene Cluster for MLF1:
Myeloid leukemia factor 1 Hs.85195 [show with all ESTs ] Unigene Representative Sequence: BX641078 15 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000491767 ENST00000355893 (uc003fcb.3 ) ENST00000484955 ENST00000359117 (uc003fbz.3 uc003fca.3 uc010hvx.3 )ENST00000498592 ENST00000477042 ENST00000495452 ENST00000471745 ENST00000497004 (uc003fbx.3 uc003fcc.3 uc003fby.3 )ENST00000469452 ENST00000482628 ENST00000478894 ENST00000487838 ENST00000466246 ENST00000392822 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 9 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 6 ): MLF1 (NM_001130156 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MLF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MLF1
Additional cDNA sequence: AK056948.1 AK096889.1 AK297488.1 AK315402.1 AY848700.1 AY848701.1 AY848702.1 BC007045.1 BC095437.1 BX641078.1 BX647666.1 L49054.1
10 DOTS entries : DT.455878 DT.91768024
DT.91768025 DT.75102922 DT.99940054 DT.86853276 DT.91768026 DT.100789206 DT.100789207 DT.40117533 24/203 AceView cDNA sequences (see all 203 ):
AI565360 NM_022443 BM823975 AI766972 AA843166 BU674539 BG546401 W56334 BC007045 BI520174 AW573287 AI686260 CA418910 AW131588 BG055075 BX647666 AA625682 AI140690 AK056948 T19178 AA974317 AL120066 AI220091 AI332753 GeneLoc Exon Structure 5/11 Alternative Splicing Database (ASD) splice patterns (SP) for MLF1 (see all 11 ) About this scheme ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b SP1 : - SP2 : - - SP3 : - - - - - SP4 : - - - - SP5 : - - - -
ECgene alternative splicing isoforms for MLF1
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Expression for MLF1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section MLF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAGGTCCTAGAbout this image MLF1 expression in embryonic tissues and stem cells About this table
See MLF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MLF1 SOURCE GeneReport for Unigene cluster: Hs.85195 UniProtKB/Swiss-Prot: MLF1_HUMAN, P58340 Tissue specificity : Most abundant in testis, ovary, skeletal muscle, heart, kidney and colon. Low expression in spleen,thymus and peripheral blood leukocytes SABiosciences Custom PCR Arrays for MLF1 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLF1
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Orthologsfor MLF1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for MLF1 gene from 5/18 species (see all 18 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves MLF11
myeloid leukemia factor 1
68.03(n) 55.61(a)
425019 XM_422822.3 XP_422822.2
lizard Reptilia MLF16
--
73(a)
1 ↔ 1
3(14155857-14158735)
zebrafish Actinopterygii Dr.124892
Transcribed sequence with weak similarity to protein more
75.43(n)
BQ074144.1
fruit fly Insecta Mlf6
Myelodysplasia/myeloid leukemia factor
19(a)
1 → many
2R(11823398-11827578)
worm Secernentea Y17G7B.176
Protein Y17G7B.17
19(a)
1 → many
II(12092358-12099925)
ENSEMBL Gene Tree for MLF1 (if available)TreeFam Gene Tree for MLF1 (if available)
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Paralogsfor MLF1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for MLF1 gene MLF2 2 2 SIMAP similar genes for MLF1 using alignment to 8 protein entries: MLF1_HUMAN (see all proteins ):DKFZp313B1621 MLF2 About GeneDecksing
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Genomic Variantsfor MLF1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 3 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for MLF1 (158288952 - 158325041 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 7 variations for MLF1 7 CNVs 79983 79982 91663 79980 91664 91665 79981
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor MLF1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 601402 OMIM disorders : 601626 UniProtKB/Swiss-Prot: MLF1_HUMAN, P58340 Note=A chromosomal aberration involving MLF1 is a cause of myelodysplastic syndrome (MDS). Translocation t(3;5)(q25.1;q34) with NPM1/NPM 10 : About MalaCards myeloid leukemia acute myeloid leukemia myelodysplastic syndrome leukemia squamous cell carcinoma lung squamous cell carcinoma gastric cancer glioblastoma carcinoma esophagitis 1 disease from the University of Copenhagen DISEASES database for MLF1 :Acute myeloid leukemia 8 Novoseek disease relationships for MLF1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: MLF1 (2 documents) Export disorders for MLF1 gene to outside databases
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Publicationsfor MLF1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MLF1 gene, integrated from 9 sources (see all 40 ):(articles sorted by number of sources associating them with MLF1) Utopia : connect your pdf to the dynamic
The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. (PubMed id 8570204) 1 , 2 , 3, 9(1996) Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3. (PubMed id 15861129) 1 , 2 , 9(2005) Structural insights of the MLF1/14-3-3 interaction. (PubMed id 22151054) 1 , 2 (2012) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) cDNA cloning and characterization of a novel gene encoding the MLF1- interacting protein MLF1IP. (PubMed id 15116101) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Detection of t(3;5) and NPM1/MLF1 rearrangement in an elderly patient with acute myeloid leukemia: clinical and laboratory study wit h review of the literature. (PubMed id 20471513) 1 , 9(2010) Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia. (PubMed id 14506644) 1 , 9(2003) NPM-MLF1 synergizes with Npm haploinsufficiency to enh ance myeloid progenitor activity. (PubMed id 22193965) 1 (2012) Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048) 1 (2011)
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External Searches for MLF1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing MLF1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing MLF1 gene
(According to HUGE )
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Specialized Databases showing MLF1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for MLF1 gene: MLF1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MLF1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
OriGene Antibodies for MLF1 OriGene shRNA RFP for MLF1 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for MLF1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for MLF1 OriGene 3'-UTR Clone for MLF1 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for MLF1 OriGene Custom Protein Services for MLF1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MLF1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MLF1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for MLF1
Recombinant Protein for MLF1
MLF1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLF1
ThermoFisher Antibody for MLF1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MLF1
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and Proteopedia 
for MLF1:
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
