Aliases for MLEC Gene
External Ids for MLEC Gene
Previous HGNC Symbols for MLEC Gene
Previous GeneCards Identifiers for MLEC Gene
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for MLEC Gene
MLEC (Malectin) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Transport to the Golgi and subsequent modification. GO annotations related to this gene include enzyme binding and carbohydrate binding.
UniProtKB/Swiss-Prot for MLEC Gene
Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).