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MLEC Gene

protein-coding   GIFtS: 53
GCID: GC12P121124

Malectin

(Previous name: KIAA0152)
(Previous symbol: KIAA0152)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
malectin1 2
KIAA01521 2 3 5
Oligosaccharyltransferase Complex Subunit (Non-Catalytic)1 2

External Ids:    HGNC: 289731   Entrez Gene: 97612   Ensembl: ENSG000001109177   OMIM: 6138025   UniProtKB: Q141653   

Export aliases for MLEC gene to outside databases

Previous GC identifers: GC12P119611 GC12P118134


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MLEC Gene:
MLEC (malectin) is a protein-coding gene. Diseases associated with MLEC include leprosy, and schizophrenia. GO annotations related to this gene include carbohydrate binding.

UniProtKB/Swiss-Prot: MLEC_HUMAN, Q14165
Function: Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the
early steps of protein N-glycosylation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the MLEC gene promoter:
         Elk-1   GATA-3   Brachyury   XBP-1   LCR-F1   CBF-C   CP1A   CP1C   Pax-4a   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMLEC promoter sequence
   Search Chromatin IP Primers for MLEC

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MLEC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

MLEC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MLEC gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P121124:  view genomic region     (about GC identifiers)

Start:
121,124,672 bp from pter      End:
121,139,667 bp from pter
Size:
14,996 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MLEC_HUMAN, Q14165 (See protein sequence)
Recommended Name: Malectin precursor  
Size: 292 amino acids; 32234 Da
Sequence caution: Sequence=BAA09773.2; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for MLEC: NX_Q14165

Explore proteomics data for MLEC at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn268
  • Modification sites at PhosphoSitePlus

  • See MLEC Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055545.1  
    ENSEMBL proteins: 
     ENSP00000228506   ENSP00000440746   ENSP00000438950   ENSP00000441247  
    Reactome Protein details: Q14165

    MLEC Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for MLEC

    MLEC Assay Products:

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    Cloud-Clone Corp. ELISAs for MLEC
    Cloud-Clone Corp. CLIAs for MLEC


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR021720 Malectin

    Graphical View of Domain Structure for InterPro Entry Q14165

    ProtoNet protein and cluster: Q14165

    UniProtKB/Swiss-Prot: MLEC_HUMAN, Q14165
    Similarity: Belongs to the malectin family


    MLEC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MLEC_HUMAN, Q14165
    Function: Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the
    early steps of protein N-glycosylation (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019899enzyme binding IPI--
    GO:0030246carbohydrate binding ISS--
         
    MLEC for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MLEC
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MLEC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MLEC
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MLEC

    miRNA
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    miRTarBase miRNAs that target MLEC:
    hsa-mir-24-3p (MIRT003889), hsa-mir-25-3p (MIRT050275), hsa-mir-375 (MIRT019896), hsa-mir-124-3p (MIRT022943), hsa-mir-296-3p (MIRT038439)

    Block miRNA regulation of human, mouse, rat MLEC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MLEC (see all 108):
    hsa-miR-3938 hsa-miR-3194-5p hsa-miR-1321 hsa-miR-607 hsa-miR-3921 hsa-miR-759 hsa-miR-3916 hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MLEC
    Predesigned siRNA for gene silencing in human, mouse, rat MLEC

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for MLEC

    Clone
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    OriGene clones in human, mouse for MLEC (see all 6)
    OriGene ORF clones in mouse, rat for MLEC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MLEC (NM_014730)
    Sino Biological Human cDNA Clone for MLEC
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MLEC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLEC

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLEC


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MLEC_HUMAN, Q14165: Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    plasma membrane2
    extracellular1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum ISS--
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016021integral component of membrane IEA--

    MLEC for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MLEC About    
    See pathways by source

    SuperPathContained pathways About
    1Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Asparagine N-linked glycosylation0.49
    Metabolism of proteins0.30
    Post-translational protein modification0.43
    N-glycan trimming in the ER and Calnexin/Calreticulin cycle0.00
    2TNF Signaling
    TNF Signaling0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Sino Biological Pathway for MLEC
        TNF Signaling

    1 Reactome Pathway for MLEC
        N-glycan trimming in the ER and Calnexin/Calreticulin cycle



    MLEC for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MLEC
    Interactions:

        Search GeneGlobe Interaction Network for MLEC

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for MLEC (Q141653 ENSP000002285064) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C12orf4Q9NQ893I2D: score=5 
    CLN3Q132863I2D: score=1 
    IKBKEQ141643I2D: score=1 
    MCCP235083I2D: score=1 
    SLC2A4P146723I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding TAS--
    GO:0018279protein N-linked glycosylation via asparagine TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    MLEC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MLEC



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MLEC gene: 
    NM_014730.2  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000228506(uc001tyy.1) ENST00000412616 ENST00000545525 ENST00000535656
    ENST00000535413
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MLEC using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MLEC (see all 108):
    hsa-miR-3938 hsa-miR-3194-5p hsa-miR-1321 hsa-miR-607 hsa-miR-3921 hsa-miR-759 hsa-miR-3916 hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MLEC
    Predesigned siRNA for gene silencing in human, mouse, rat MLEC
    Clone
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    OriGene clones in human, mouse for MLEC (see all 6)
    OriGene ORF clones in mouse, rat for MLEC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MLEC (NM_014730)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MLEC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MLEC
    Primer
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    OriGene qPCR primer pairs and template standards for MLEC
    OriGene qSTAR qPCR primer pairs in human, mouse for MLEC
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MLEC
      QuantiTect SYBR Green Assays in human, mouse, rat MLEC
      QuantiFast Probe-based Assays in human, mouse, rat MLEC

    Selected AceView cDNA sequences (see all 786):

    AI128671 AA343725 BQ055353 AA219772 BP428791 AA232554 AA488941 BM456352 
    BQ774109 AI358179 AL710396 AI817842 CA423273 AA171885 AA226950 F02226 
    AA565671 AI802576 BQ878042 BM761732 AW515758 BQ574473 BG575775 BU855571 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for MLEC    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b
    SP1:        -                                                               
    SP2:                                                                        
    SP3:                                -                                       
    SP4:                                                        -               
    SP5:                                                        -               


    ECgene alternative splicing isoforms for MLEC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MLEC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCCCATCC
    MLEC Expression
    About this image

    MLEC Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MLEC Protein Expression
        Custom PCR Arrays for MLEC
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MLEC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MLEC gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mlec1 , 5 malectin1, 5 88.47(n)1
    94.12(a)1
      5 (55.99 cM)5
    1091541  NM_175403.31  NP_780612.21 
     1151429815 
    chicken
    (Gallus gallus)
    Aves MLEC1 malectin 79.76(n)
    86.23(a)
      416971  XM_415264.4  XP_415264.3 
    lizard
    (Anolis carolinensis)
    Reptilia MLEC6
    malectin
    86(a)
    1 ↔ 1
    GL343338.1(166738-173782)
    African clawed frog
    (Xenopus laevis)
    Amphibia kiaa0152-prov2 hypothetical protein MGC52710 78.84(n)    BC042341.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mlec1 malectin 73.82(n)
    82.59(a)
      569613  NM_001113618.1  NP_001107090.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG92571 CG9257 55.33(n)
    48.58(a)
      35375  NM_136243.3  NP_610087.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F44E2.101 F44E2.10 49.65(n)
    37.66(a)
      185734  NM_066550.3  NP_498951.1 


    ENSEMBL Gene Tree for MLEC (if available)
    TreeFam Gene Tree for MLEC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MLEC gene

    MLEC for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MLEC
    PGOHUM00000259280


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MLEC (see all 318)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs742400751,2
    C--118132319(+) GAGAAT/CAGTAG 1 -- us2k12Minor allele frequency- C:0.20CSA EA 122
    rs1438138661,2
    --118132382(+) ACTTTC/GGGAGG 1 -- us2k10--------
    rs1875515691,2
    C--118132390(+) AGGCCA/GCGGAC 1 -- us2k10--------
    rs1149718431,2
    C,F--118132409(+) CAGGAG/AATCGA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1505981411,2
    --118132452(+) TCTAAG/TAAAAA 1 -- us2k10--------
    rs21760861,2
    C,F,A--118132487(-) AGGCGT/CGCGCC 1 -- us2k16Minor allele frequency- C:0.45NA WA CSA 11
    rs21400931,2
    C,F,A,H--118132558(+) TTGCCG/ATGAGC 1 -- us2k19Minor allele frequency- A:0.39NA WA CSA 18
    rs1133879211,2
    C--118132626(+) AAAAA-/AGAAAC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1919778661,2
    C--118132701(+) CAAAAC/TAGGGG 1 -- us2k10--------
    rs795070501,2
    --118132810(+) GATAGA/TCTCTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MLEC (121124672 - 121139667 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MLEC:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659790CNV Deletion23128226
    nsv899557CNV Loss21882294
    nsv521928CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MLEC
    DNA2.0 Custom Variant and Variant Library Synthesis for MLEC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613802    OMIM disorders: --

    2 diseases for MLEC:    
    About MalaCards
    leprosy    schizophrenia

    1 disease from the University of Copenhagen DISEASES database for MLEC:
    Leprosy

    MLEC for disorders           About GeneDecksing

    Genetic Association Database (GAD): MLEC
    Human Genome Epidemiology (HuGE) Navigator: MLEC (2 documents)

    Export disorders for MLEC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MLEC gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with MLEC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PubMed id 20347265)1, 4 Xu Y....Liu P. (Schizophr. Res. 2010)
    2. Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. (PubMed id 18524852)1, 3 Schallus T....Muhle-Goll C. (Mol. Biol. Cell 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2 Nagase T.... Nomura N. (DNA Res. 1995)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins. (PubMed id 22988243)1 Qin S.Y....Yamamoto K. (J. Biol. Chem. 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Role of malectin in Glc(2)Man(9)GlcNAc(2)-dependent quality control of I+1-antitrypsin. (PubMed id 21813736)1 Chen Y....Yamamoto K. (Mol. Biol. Cell 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9761 HGNC: 28973 AceView: KIAA0152 Ensembl:ENSG00000110917 euGenes: HUgn9761
    ECgene: MLEC H-InvDB: MLEC

    (According to HUGE)
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    HUGE: KIAA0152

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MLEC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MLEC gene:
    Search GeneIP for patents involving MLEC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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