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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MKX Gene

protein-coding   GIFtS: 51
GCID: GC10M028003

Mohawk Homeobox

(Previous names: chromosome 10 open reading frame 48, iroquois homeobox protein-like...)
(Previous symbols: C10orf48, IRXL1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mohawk Homeobox1 2     IFRX2 5
IRXL11 2 3 5     Chromosome 10 Open Reading Frame 481
C10orf481 2 3     Homeobox Protein Mohawk2
Iroquois Homeobox Protein-Like 11 2     Iroquois Family Related Homeodomain Protein2

External Ids:    HGNC: 237291   Entrez Gene: 2830782   Ensembl: ENSG000001500517   OMIM: 6013325   UniProtKB: Q8IYA73   

Export aliases for MKX gene to outside databases

Previous GC identifer: GC10M027682


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MKX Gene:
The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion.
Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants
encoding the same protein have been found for this gene.(provided by RefSeq, Jun 2011)

GeneCards Summary for MKX Gene: 
MKX (mohawk homeobox) is a protein-coding gene. Diseases associated with MKX include smallpox. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is IRX1.

UniProtKB/Swiss-Prot: MKX_HUMAN, Q8IYA7
Function: May act as a morphogenetic regulator of cell adhesion (By similarity)

Gene Wiki entry for MKX Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_008705.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MKX gene promoter:
         Elk-1   Pax-5   POU3F1   STAT5A   IRF-1   Cdc5   AP-2beta   Cart-1   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMKX promoter sequence
   Search SABiosciences Chromatin IP Primers for MKX

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MKX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p12.1   Ensembl cytogenetic band:  10p12.1   HGNC cytogenetic band: 10p12.1

MKX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MKX gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M028003:  view genomic region     (about GC identifiers)

Start:
27,961,803 bp from pter      End:
28,034,989 bp from pter
Size:
73,187 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MKX_HUMAN, Q8IYA7 (See protein sequence)
Recommended Name: Homeobox protein Mohawk  
Size: 352 amino acids; 39331 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: B3KWM5

Explore the universe of human proteins at neXtProt for MKX: NX_Q8IYA7

Explore proteomics data for MKX at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IYA7

  • MKX Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MKX Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001229631.1  NP_775847.2  

    ENSEMBL proteins: 
     ENSP00000364946   ENSP00000452751   ENSP00000453746   ENSP00000400896  

    Human Recombinant Protein Products for MKX: 
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    OriGene Protein Over-expression Lysate for MKX
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    Novus Biologicals MKX Proteins
    Novus Biologicals MKX Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MKX 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    MKX for ontologies           About GeneDecksing



    MKX Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TALE: Homeoboxes / TALE class

    4 InterPro protein domains:
     IPR008422 Homeobox_KN_domain
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q8IYA7

    ProtoNet protein and cluster: Q8IYA7

    UniProtKB/Swiss-Prot: MKX_HUMAN, Q8IYA7
    Similarity: Belongs to the TALE/IRO homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    MKX for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MKX_HUMAN, Q8IYA7
    Function: May act as a morphogenetic regulator of cell adhesion (By similarity)

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IEA--
    GO:0001085RNA polymerase II transcription factor binding IEA--
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0005515protein binding ----
         
    MKX for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MKX:
     Increased cilium length after  

         4 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Mkx):
     limbs/digits/tail  muscle  no phenotypic analysis  skeleton 

    MKX for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for MKX: Mkxtm1Miu Mkxtm1.2Jian

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MKX 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MKX

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MKX 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MKX 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MKX
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate MKX (see all 29):
    hsa-miR-548j hsa-miR-548i hsa-miR-485-3p hsa-miR-374a hsa-miR-570 hsa-miR-1304 hsa-miR-124 hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidMKX 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MKX

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for MKX (Q8IYA73 ENSP000003649464) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTF2A1P526553, ENSP000002981734I2D: score=1 STRING: ENSP00000298173
    TBPP202263, ENSP000002303544I2D: score=1 STRING: ENSP00000230354
    SIN3AQ96ST33, ENSP000003536224I2D: score=1 STRING: ENSP00000353622
    GTF2BQ004033, ENSP000003595314I2D: score=1 STRING: ENSP00000359531
    HDAC1Q135473, ENSP000003626494I2D: score=1 STRING: ENSP00000362649
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0002932tendon sheath development IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006366transcription from RNA polymerase II promoter ----
    GO:0007517muscle organ development ISS16408284

    MKX for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MKX

    Search CenterWatch for drugs/clinical trials and news about MKX

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MKX gene (2 alternative transcripts): 
    NM_001242702.1  NM_173576.2  

    Unigene Cluster for MKX:

    Mohawk homeobox
    Hs.128193  [show with all ESTs]
    Unigene Representative Sequence: NM_173576
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000375790(uc001itx.4) ENST00000460919 ENST00000561227 ENST00000419761(uc001ity.4)

    miRNA
    Products:
         
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    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate MKX (see all 29):
    hsa-miR-548j hsa-miR-548i hsa-miR-485-3p hsa-miR-374a hsa-miR-570 hsa-miR-1304 hsa-miR-124 hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidMKX 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MKX
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MKX

    Additional mRNA sequence: 

    AK125339.1 BC036207.1 

    2 DOTS entries:

    DT.97774780  DT.40127308 

    24/39 AceView cDNA sequences (see all 39):

    BF108805 AK125339 F01353 Z41276 AI075375 BI491189 BQ961518 AW298102 
    BM542857 BI769578 BF940586 BM474155 BC036207 AI910541 AI805198 BI547447 
    Z41858 NM_173576 AI339844 BQ937643 BF058244 AI910533 CB121713 BM977383 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MKX    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:                                            -         
    SP2:                                            -         
    SP3:                                                      


    ECgene alternative splicing isoforms for MKX

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MKX expression in normal human tissues (normalized intensities)      MKX embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MKX Expression
    About this image


    MKX expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Fibroblast
             X-gene Foreskin Fibroblasts   
     
     Tendon & Ligament (Muscoskeletal System)    fully expand to see all 4 entries
             Early Tenocyte Cells Limb Tendon Primordia
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mandibular Process
             Normal Human osteoblasts (NHOST)   
     
     Uncategorized (Uncategorized)    fully expand to see all 2 entries
             PureStem Progenitor E72
     
     Dermis (Uncategorized)    fully expand to see all 2 entries
             BH2 Dermal Fibroblasts   

    See MKX Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MKX

    SOURCE GeneReport for Unigene cluster: Hs.128193
        SABiosciences Expression via Pathway-Focused PCR Array including MKX: 
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MKX gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mkx1 , 5 mohawk homeobox1, 5 85.51(n)1
    89.2(a)1
      18 (4.53 cM)5
    2107191  NM_177595.41  NP_808263.21 
     69350005 
    chicken
    (Gallus gallus)
    Aves MKX1 mohawk homeobox 81.09(n)
    85.97(a)
      771284  XM_001233725.2  XP_001233726.2 
    lizard
    (Anolis carolinensis)
    Reptilia MKX6
    Uncharacterized protein
    87(a)
    1 ↔ 1
    6(14173003-14238954)
    zebrafish
    (Danio rerio)
    Actinopterygii mkxa1 mohawk homeobox a 66.67(n)
    72.09(a)
      799136  NM_001098733.2  NP_001092203.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG116176
    --
    19(a)
    1 ↔ 1
    2L(204743-207297)


    ENSEMBL Gene Tree for MKX (if available)
    TreeFam Gene Tree for MKX (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MKX gene
    IRX12  IRX32  IRX52  IRX22  IRX62  IRX42  
    2 SIMAP similar genes for MKX using alignment to 3 protein entries:     MKX_HUMAN (see all proteins):
    TGIF1    PKNOX1

    MKX for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1546 SNPs in MKX are shown (see all 1546)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs719477991,2
    C--27699748(+) AAAAT-/AATA  
      TATA
    /T
    ATATA
    2 -- int10--------
    rs1468334571,2
    C--27713965(+) AAAAA-/TCGACT 2 -- int10--------
    rs719962291,2
    C--27725221(+) AAAAA-/GGAGAG 2 -- int10--------
    rs30631911,2
    C--27731941(-) AAAGT-/AA/AAA
            
    AAAAA
    4 -- int1 cds1 trp30--------
    rs28155491,2
    C,F,A--27867646(+) GAAACC/TAGATA 2 -- ds500112Minor allele frequency- N:0.03EA NA CSA WA 584
    rs796776261,2
    F--27867659(+) AATGAC/TTAAGT 2 -- ds50012Minor allele frequency- T:0.04CSA WA 120
    rs1472652961,2
    C--27867750(+) ACAAA-/TAATGC 2 -- ds50010--------
    rs28155501,2
    C,F,A,H--27867788(+) ATTACG/CTGAAA 2 -- ds500123Minor allele frequency- C:0.18NS EA NA WA CSA 2144
    rs28155511,2
    C,F,A,H--27867855(+) GTCTTT/CGAAAG 2 -- ds500127Minor allele frequency- C:0.25NS EA NA CSA WA 2914
    rs47492591,2
    C,F,A,H--27867916(+) ACTCCC/TATATC 2 -- ds500127Minor allele frequency- T:0.20NS EA NA CSA WA 2974

    HapMap Linkage Disequilibrium report for MKX (27961803 - 28034989 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for MKX:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2677848CNV Deletion23128226
    esv2734661CNV Deletion23290073
    esv4953CNV Deletion18987735
    esv2734639CNV Deletion23290073
    esv2734650CNV Deletion23290073
    esv2734606CNV Deletion23290073
    nsv831813CNV Loss17160897
    esv7833CNV Loss19470904

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MKX
    DNA2.0 Custom Variant and Variant Library Synthesis for MKX

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601332    OMIM disorders: --

    2 diseases for MKX:    About MalaCards
    smallpox    


    MKX for disorders           About GeneDecksing

    Genetic Association Database (GAD): MKX
    Human Genome Epidemiology (HuGE) Navigator: MKX (1 document)

    Export disorders for MKX gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MKX gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with MKX)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1, 4 Jugessur A....Murray J.C. (2010)
    2. Mohawk is a novel homeobox gene expressed in the developing mouse embryo. (PubMed id 16408284)1, 3 Anderson D.M....Rawls A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. In silico characterization of an Iroquois family-related homeodomain protein. (PubMed id 16077953)1, 9 Weinmann A....Teufel A. (2005)
    5. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    6. Genome-wide association study of antibody response to smallpox vaccine. (PubMed id 22542470)1 Ovsyannikova I.G....Poland G.A. (2012)
    7. The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. (PubMed id 20696843)1 Liu W....Jiang R. (2010)
    8. The Mohawk homeobox gene is a critical regulator of t endon differentiation. (PubMed id 20498044)1 Ito Y....Asahara H. (2010)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    10. The homeobox gene Mohawk represses transcription by recruiting the sin3A/HDAC co-repressor complex. (PubMed id 19235719)1 Anderson D.M....Rawls A. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 283078 HGNC: 23729 AceView: C10orf48 Ensembl:ENSG00000150051 euGenes: HUgn283078
    ECgene: MKX H-InvDB: MKX

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MKX Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MKX gene:
    Search GeneIP for patents involving MKX

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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