MKS1 Gene
protein-coding GIFtS: 51
GCID: GC17M056282
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|
Meckel syndrome, type 1
(Previous symbol: MKS)
| |
Aliases
for MKS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Meckel Syndrome, Type 11 2 | | MES2 | | BBS131 2 5 | | FABB Proteome-Like Protein2 | | MKS1 2 5 | | Meckel Syndrome Type 1 Protein2 | | POC121 2 | | POC12 Centriolar Protein Homolog2 | | FLJ203451 | | |
Export aliases for MKS1 gene to outside databasesPrevious GC identifers: GC17U990060 GC17M053638 GC17M051643 |
Summaries
for MKS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MKS1:
The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium inciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type13. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Sep2009)
UniProtKB/Swiss-Prot: MKS1_HUMAN, Q9NXB0Function: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia andacting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involvedin centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure andfunction, including a role in regulating length and appropriate number through modulating centrosome duplication.Required for cell branching morphology
Gene Wiki entry for MKS1
|
Genomic Views
for MKS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MKS1 gene promoter:
Nkx6-1 p53 STAT3 RelA IRF-1 NF-kappaB NF-kappaB1 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MKS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MKS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q22 Ensembl cytogenetic band: 17q22 HGNC cytogenetic band: 17q21-q24MKS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M056282: view genomic region
(about GC identifiers)
Start:
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56,282,797 bp from pter |
End:
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56,296,966 bp from pter |
Size:
|
14,170 bases |
Orientation:
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minus strand |
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Proteins
for MKS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MKS1_HUMAN, Q9NXB0 (See
protein sequence)Recommended Name: Meckel syndrome type 1 protein Size: 559 amino acids; 64528 Da
Subunit: Part of the tectonic-like complex (also named B9 complex) (By similarity). Interacts with TCTN3 and AHI1 (Bysimilarity). Interacts with FLNA
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, centrosome. Note=Localizesat the transition zone, a region between the basal body and the ciliary axoneme (By similarity)
Sequence caution: Sequence=AAH10061.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA91105.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B7WNX4 F5H885 Q284T0 Q96G13Alternative splicing: 3 isoforms: Q9NXB0-1 Q9NXB0-2 Q9NXB0-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MKS1: NX_Q9NXB0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NXB0
MKS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001159399.1 NP_060247.2
ENSEMBL proteins: ENSP00000376827 ENSP00000316631 ENSP00000442096 ENSP00000376828 ENSP00000462179 ENSP00000462460 ENSP00000463826 ENSP00000462129 ENSP00000462423 ENSP00000462411 ENSP00000338407 ENSP00000443012
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
MKS1 for ontologies About GeneDecksing
MKS1 Antibody Products:
Assay Products for MKS1: |
Protein
Domains /
Families
for MKS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MKS1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NXB0ProtoNet protein and cluster: Q9NXB0 UniProtKB/Swiss-Prot: MKS1_HUMAN, Q9NXB0Similarity: Contains 1 B9 domain |
Function
for MKS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MKS1_HUMAN, Q9NXB0Function: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia andacting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involvedin centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure andfunction, including a role in regulating length and appropriate number through modulating centrosome duplication.Required for cell branching morphology
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): MKS1 (NM_017777) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MKS1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MKS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MKS1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
MKS1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MKS1:
Animal Models:
15/20 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Mks1) (see all 20):
MKS1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MKS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MKS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/14 Interacting proteins for MKS1 (Q9NXB02, 3 ENSP000003768274) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
MKS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MKS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MKS1
Search CenterWatch for drugs/clinical trials and news about MKS1
|
Transcripts
for MKS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MKS1 gene (2 alternative transcripts): NM_001165927.1 NM_017777.3 Unigene Cluster for MKS1: Meckel syndrome, type 1 Hs.408843 [show with all ESTs]Unigene Representative Sequence: NM_01777715 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393119(uc002ivr.2 uc010wnq.2 uc021uam.1) ENST00000313863
ENST00000537529 ENST00000393120 ENST00000583577 ENST00000577315 ENST00000577824
ENST00000585134 ENST00000579358 ENST00000581761 ENST00000580127 ENST00000578789
ENST00000581180 ENST00000337050 ENST00000546108
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MKS1 (NM_017777) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MKS1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MKS1 |
Additional cDNA sequence: AK000352.1 AK301020.1 AK310815.1 BC010061.2 CR457229.1 DQ185029.1 9 DOTS entries: DT.114202 DT.97791161 DT.97836893 DT.75110828 DT.40254276 DT.120962415 DT.100801416 DT.120962405 DT.86858279 24/140 AceView cDNA sequences (see all 140): AI041746 BU848884 BX107256 BX472007 BG777703 AL524883 CR606585 AI675614 N32900 BM746116 BQ014063 BE378121 BX350482 BQ953274 BE208563 BM128665 AI075045 N42042 AA478968 AI684299 BM791742 BU148482 BM741365 AA928120
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MKS1 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b |
|---|
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| SP1: | | | | | | | | | | | - | | | | | | | | - | | | | | | - | | - | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for MKS1
|
Expression
for MKS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MKS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGAGGCCC
About this image
See MKS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MKS1
SOURCE GeneReport for Unigene cluster: Hs.408843
SABiosciences Expression via Pathway-Focused PCR Array including MKS1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MKS1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MKS1 |
Orthologs
for MKS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MKS1 gene from 5/19 species (see all 19) About this table
ENSEMBL Gene Tree for MKS1 (if available)
TreeFam Gene Tree for MKS1 (if available) |
Paralogs
for MKS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MKS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MKS1 (56282797 - 56296966 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MKS1: --
Human Gene Mutation Database (HGMD): MKS1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MKS1 |
|
Disorders
/ Diseases
for MKS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MKS1 for disorders About GeneDecksing
OMIM gene information: 609883
OMIM disorders: 249000 209900
UniProtKB/Swiss-Prot: MKS1_HUMAN, Q9NXB0
Defects in MKS1 are the cause of Meckel syndrome type 1 (MKS1) [MIM:249000]. MKS1 is an autosomal recessivedisorder characterized by a combination of renal cysts and variably associated features including developmentalanomalies of the central nervous system (typically encephalocele), hepatic ductal dysplasia and cysts, and polydactyly Defects in MKS1 are the cause of Bardet-Biedl syndrome type 13 (BBS13) [MIM:209900]. Bardet-Biedl syndrome(BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentaryretinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondaryfeatures include diabetes mellitus, hypertension and congenital heart disease. A relatively high incidence of BBS isfound in the mixed Arab populations of Kuwait and in Bedouin tribes throughout the Middle East, most likely due to thehigh rate of consaguinity in these populations and a founder effect
16  diseases for MKS1: About MalaCardsmeckel syndrome, type 1 meckel syndrome bardet-biedl syndrome bardet-biedl syndrome 13
senior-loken syndrome encephalocele encephaloceles pigmentary retinopathy
congenital nystagmus joubert syndrome nephronophthisis cystic kidney
nystagmus polydactyly myelofibrosis hepatitis
3 diseases from the University of Copenhagen DISEASES database for MKS1:Polydactyly Cystic kidney Nephronophthisis GeneTests: MKS1
Bardet-Biedl Syndrome
Human Genome Epidemiology (HuGE) Navigator: MKS1 (3 documents)
Export disorders for MKS1 gene to outside databases
|
Publications
for MKS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MKS1 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with MKS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome. (PubMed id 18327255)1, 2, 3 Leitch C.C....Katsanis N. (2008)
- MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome. (PubMed id 16415886)1, 2, 3 Kyttala M....Kestila M. (2006)
- The Meckel-Gruber syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation. (PubMed id 17185389)1, 2, 9 Dawe H.R.... Johnson C.A. (2007)
- Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins. (PubMed id 19208769)1, 2, 9 Bialas N.J.... Leroux M.R. (2009)
- Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3. (PubMed id 19515853)1, 2 Tammachote R.... Harris P.C. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The locus for Meckel syndrome with multiple congenital anomalies maps to chromosome 17q21-q24. (PubMed id 7550354)1, 3 Paavola P....Peltonen L. (1995)
- A disease causing deletion of 29 base pairs in intron 15 in the MKS1 gene is highly associated with the campomelic variant of the Meckel-Gruber syndrome. (PubMed id 17935508)1, 9 Auber B....Rehder H. (2007)
- Spectrum of MKS1 and MKS3 mutations in Meckel syndrome: a genotype-phenotype correlation. Mutation in brief #960. Online. (PubMed id 17397051)1, 9 Khaddour R....Attie-Bitach T. (2007)
|
External Searches for MKS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MKS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MKS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MKS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MKS1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/MKS1 |
|
| | |
About This Section
| Patent Information for MKS1 gene:
Search GeneIP for patents involving MKS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MKS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MKS1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MKS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MKS1 | | | OriGene Protein Over-expression Lysate for MKS1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MKS1 | | OriGene 3'-UTR Clone for MKS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MKS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MKS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MKS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MKS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MKS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MKS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MKS1 |
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| |  |  |  |  | | | | |
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 | | | MKS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MKS1 |
|  |  |  | | | | Search ThermoFisher Antibodies for MKS1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MKS1 |
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